Tigecycline
November 1996). "A novel mechanism of action of tetracyclines: effects on nitric oxide synthases". Proceedings of the National ...
5-HT2B receptor
"PDZ-dependent activation of nitric-oxide synthases by the serotonin 2B receptor". The Journal of Biological Chemistry. 275 (13 ...
HSPA8
Kiang JG (Dec 2004). "Inducible heat shock protein 70 kD and inducible nitric oxide synthase in hemorrhage/resuscitation- ...
Coronary vasospasm
... these agents work by enhancing the production of nitric oxide from endothelial nitric oxide synthase. Normally, nitric oxide ... Vasodilatory agents with mechanisms dependent on a functional endothelial nitric oxide synthase can cause vasoconstriction ... Endothelial dysfunction wherein there is a deficiency in the production of nitric oxide has been found to be associated with ... the pathogenesis of coronary vasospasm through their damaging effects on vascular endothelial cells and degrading nitric oxide ...
DLGAP1
2001). "The hDLG-associated protein DAP interacts with dynein light chain and neuronal nitric oxide synthase". Genes Cells. 5 ( ...
Striatum
Also, there are GABAergic interneurons that express tyrosine hydroxylase, somatostatin, nitric oxide synthase and neuropeptide- ...
Atrial natriuretic peptide receptor
Instead, vascular endothelial cells will use L-arginine to make nitric oxide via nitric oxide synthase. The nitric oxide will ... The nitroglycerine will be metabolized to nitric oxide, which will stimulate soluble guanylyl cyclase. This will result in a ...
Reactive nitrogen species
... produced via the enzymatic activity of inducible nitric oxide synthase 2 (NOS2) and NADPH oxidase respectively. NOS2 is ... RNS are produced in animals starting with the reaction of nitric oxide (•NO) with superoxide (O2•−) to form peroxynitrite (ONOO ... Guzik TJ, West NE, Pillai R, Taggart DP, Channon KM (June 2002). "Nitric oxide modulates superoxide release and peroxynitrite ... Pacher P, Beckman JS, Liaudet L (January 2007). "Nitric oxide and peroxynitrite in health and disease". Physiol. Rev. 87 (1): ...
Plasma membrane Ca2+ ATPase
Isoform PMCA4b interacts with nitric oxide synthase and reduces synthesis of nitric oxide by that enzyme. PMCA isoform 4 has a ... a major regulator of nitric oxide synthase I". J. Cell Biol. 155 (2): 201-205. doi:10.1083/jcb.200104131. PMC 2198825. PMID ...
Chlamydia pneumoniae
Long-term potentiation
Nitric oxide synthase activity may also result in the subsequent activation of guanylyl cyclase and PKG. Similarly, activation ... Early thoughts focused on nitric oxide, while most recent evidence points to cell adhesion proteins. Before the local protein ... Lu YF, Kandel ER, Hawkins RD (December 1999). "Nitric oxide signaling contributes to late-phase LTP and CREB phosphorylation in ...
Claudius cell
... localization of nitric oxide synthase". Acta Otolaryngol Suppl (554): 12-6. doi:10.1080/03655230410018444. PMID 15513504. Jahn ...
4-PPBP
... decreases neuronal nitric oxide synthase (nNOS) activity and ischemia-evoked nitric oxide (NO) production. 4-PPBP ... piperidine modulates neuronal nitric oxide synthase/postsynaptic density-95 coupling mechanisms and protects against neonatal ...
DYNLL2
2001). "The hDLG-associated protein DAP interacts with dynein light chain and neuronal nitric oxide synthase". Genes Cells. 5 ( ...
Dynorphin
Further, authors found that administration of nitric oxide synthase (NOS) inhibitors reduced dynorphin A1-17 levels in the ... Sharma HS, Alm P (2002). "Nitric oxide synthase inhibitors influence dynorphin A (1-17) immunoreactivity in the rat brain ... They further hypothesized that nitric oxide was part of this mechanism. Ansonoff et al. found that hypothermic effects are ...
VAC14
Human Vac14/ArPIKfyve also interacts with the PDZ (post-synaptic density) domain of neuronal nitric oxide synthase but the ... Lemaire JF, McPherson PS (December 2006). "Binding of Vac14 to neuronal nitric oxide synthase: Characterisation of a new ...
Acadesine
AICAR triggers a preconditioned anti-inflammatory state by increasing NO production from endothelial nitric oxide synthase. ...
S100-A1
... deficiency impairs postischemic angiogenesis via compromised proangiogenic endothelial cell function and nitric oxide synthase ...
Dipshikha Chakravortty
Chakravortty D, Hensel M, 2003, Inducible nitric oxide synthase and control of intracellular bacterial pathogens. Microbes ... SPI2-dependent suppression of inducible nitric oxide synthase in activated macrophages. Microbiology, 155, 2476-2489. 125. ... Morikawa A, Koide N, Kato Y, Sugiyama T, Chakravortty D, Yoshida T, Yokochi T,2000, Augmentation of nitric oxide production by ... Eswarappa SM, Pareek V,Chakravortty D,2008, Role of actin cytoskeleton in LPS-induced NF-kappaB activation and nitric oxide ...
Fire ant
... a potent and selective inhibitor of neuronal nitric oxide synthase". International Journal of Toxicology. 22 (2): 81-6. doi: ...
Csaba Szabo (pharmacologist)
"Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock". ... such as selective inhibitors of the inducible isoform of nitric oxide synthase. Subsequent work conducted by Szabo and his ... a small diffusible biological mediator produced by nitric oxide synthases) in the blood vessel dysfunction and organ injury ... a potent and selective inhibitor of inducible nitric oxide synthase". Proceedings of the National Academy of Sciences. 91 (26 ...
Hemoprotein
Nitric Oxide Synthase Activity and Mitochondrial Function in Fish Hearts". Antioxidants. 10 (7): 1072. doi:10.3390/ ... Oxygen (O2), nitric oxide (NO), carbon monoxide (CO) and hydrogen sulfide (H2S) bind to the iron atom in heme proteins. Once ... Found in neurons, nueroglobin is responsible for driving nitric oxide to promote neuron cell survival Neuroglobin is believed ...
Muscarinic acetylcholine receptor M2
... muscarinic receptor subtypes couple to activation of endothelial nitric oxide synthase". Pharmacology. 61 (1): 37-42. doi: ...
Gambierol
An increase in intracellular calcium concentration also activates the nitric oxide synthase to produce nitric oxide. In ... nitric oxide forms peroxynitrite and causes oxidative stress in different sorts of tissues. This explains the toxic symptoms ... "Vascular Endothelial Growth Factor Signals Endothelial Cell Production of Nitric Oxide and Prostacyclin through Flk-1/KDR ...
Morphine
Herman BH, Vocci F, Bridge P (December 1995). "The effects of NMDA receptor antagonists and nitric oxide synthase inhibitors on ... Opioids also may act on the gut indirectly through tonic gut spasms after inhibition of nitric oxide generation. This effect ... Stefano GB, Zhu W, Cadet P, Bilfinger TV, Mantione K (March 2004). "Morphine enhances nitric oxide release in the mammalian ... Calignano A, Moncada S, Di Rosa M (December 1991). "Endogenous nitric oxide modulates morphine-induced constipation". ...
Tension headache
Briefly, the enzyme nitric oxide synthase (NOS) forms NO which ultimately results in vasodilatation and activation of central ... Ashina M, Lassen LH, Bendtsen L, Jensen R, Olesen J (January 1999). "Effect of inhibition of nitric oxide synthase on chronic ... and nitric oxide (NO). Of the neurotransmitters, NO plays a major role in central pain pathways and likely contributes to the ...
Capitella teleta
"Inhibitors of nitric oxide synthase induce larval settlement and metamorphosis of the polychaete annelid Capitella teleta". ... Dai, Lina; Banta, Gary T.; Selck, Henriette; Forbes, Valery E. (2015-10-01). "Influence of copper oxide nanoparticle form and ... copper oxide nanoparticles, and silver nanoparticles. Recently, the effects of the fluoranthene-spiked sediments on the gut ...
2,5-Dimethoxy-4-iodoamphetamine
"Serotonin 5-HT2A receptor activation inhibits cytokine-stimulated inducible nitric oxide synthase in C6 glioma cells". Ann. N. ...
Solenopsin
... inhibits neuronal nitric oxide synthase (nNOS) in a manner that appears to be non-competitive with L-arginine, and inhibits ... a potent and selective inhibitor of neuronal nitric oxide synthase". Int J Toxicol. 22 (2): 81-6. doi:10.1080/10915810305090. ...
TNF inhibitor
"Serotonin 5-HT2A receptor activation inhibits cytokine-stimulated inducible nitric oxide synthase in C6 glioma cells". Annals ...