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*  Nitric oxide synthase
Biological functions of nitric oxide Nitric-oxide synthase (NAD(P)H-dependent) Nitric oxide synthase 2 (inducible) PDB: 3N5P​; ... Nitric oxide synthases (EC 1.14.13.39) (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L- ... "Nitric oxide down-regulates hepatocyte-inducible nitric oxide synthase gene expression". Arch Surg. 132 (11): 1177-83. doi: ... which is then recaptured to enable nitric oxide release. The first nitric oxide synthase to be identified was found in neuronal ...
*  Nitric oxide synthase 2 (inducible)
Nitric oxide synthase, inducible is an enzyme that in humans is encoded by the NOS2 gene. Nitric oxide is a reactive free ... "Entrez Gene: NOS2A nitric oxide synthase 2A (inducible, hepatocytes)". Felley-Bosco E, Bender FC, Courjault-Gautier F, Bron C, ... Nitric oxide synthase 2A has been shown to interact with Caveolin 1 and Rac2. GRCh38: Ensembl release 89: ENSG00000007171 - ... This gene encodes a nitric oxide synthase which is expressed in the liver and is inducible by a combination of ...
*  Nitric-oxide synthase (NAD(P)H-dependent)
... (EC 1.14.13.165, nitric oxide synthetase, NO synthase) is an enzyme with systematic ... 2 nitric oxide + NAD(P)+ + 2 H2O Nitric-oxide synthase (NAD(P)H-dependent) binds heme (iron protoporphyrin IX) and ... "Bacterial flavodoxins support nitric oxide production by Bacillus subtilis nitric-oxide synthase". J. Biol. Chem. 282 (4): 2196 ... Nitric oxide synthase Wang, Z.Q.; Lawson, R.J.; Buddha, M.R.; Wei, C.C.; Crane, B.R.; Munro, A.W.; Stuehr, D.J. (2007). " ...
*  Citrulline
"Nos2 - Nitric Oxide Synthase". Uniprot.org. Uniprot Consortium. Retrieved 10 February 2015. Cox M, Lehninger AL, Nelson DR ( ... catalyzed by nitric oxide synthase. Citrulline is made from ornithine and carbamoyl phosphate in one of the central reactions ... Citrulline is also produced as a byproduct of the enzymatic production of nitric oxide from the amino acid arginine, ... which is then further oxidized to citrulline concomitant with release of nitric oxide. Several proteins contain citrulline as a ...
*  Naringenin
Olszanecki, R.; Gebska, A.; Kozlovski, V. I.; Gryglewski, R. J. (2002-12-01). "Flavonoids and nitric oxide synthase". Journal ...
*  CAMK1
Komeima K, Hayashi Y, Naito Y, Watanabe Y (2000). "Inhibition of neuronal nitric-oxide synthase by calcium/ calmodulin- ... 1999). "Regulation of neuronal nitric-oxide synthase by calmodulin kinases". J. Biol. Chem. 274 (29): 20597-602. doi:10.1074/ ... "Nitric oxide synthase regulatory sites. Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/ ... 2002). "Calmodulin-dependent kinase I regulates adrenal cell expression of aldosterone synthase". Endocrinology. 143 (9): 3651- ...
*  CAMK2A
Bredt DS, Ferris CD, Snyder SH (1992). "Nitric oxide synthase regulatory sites. Phosphorylation by cyclic AMP-dependent protein ...
*  CAMK4
Komeima K, Hayashi Y, Naito Y, Watanabe Y (2000). "Inhibition of neuronal nitric-oxide synthase by calcium/ calmodulin- ... 1999). "Regulation of neuronal nitric-oxide synthase by calmodulin kinases". J. Biol. Chem. 274 (29): 20597-602. doi:10.1074/ ... "Nitric oxide synthase regulatory sites. Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/ ...
*  Folliculostellate cell
Knowles, R. G.; Moncada, S. (1994-03-01). "Nitric oxide synthases in mammals". The Biochemical Journal. 298 ( Pt 2): 249-258. ... Nitric Oxide (NO), is reported to be a key modulator of endocrine cell function and has been shown that FS cells (and some ... endocrine cells) contain neuronal NO synthase, a key NO production enzyme which is responsible for the production of NO from L- ...
*  PGO waves
Nitric oxide synthase inhibition decreases pontine acetylcholinerelease. NeuroReport 6:1525-1529. Morrison, A.R., and Pompeiano ... Nitroxergic neurons use nitric oxide (NO) as a neurotransmitter. In theory, the increase of nitric oxide is seen as an ... This stems from animal testing that has shown increases in PGO waves as nitric oxide levels were increased in the pons. GABA- ...
*  Arginine
... from arginine itself via nitric oxide synthase (NOS), as a byproduct of the production of nitric oxide for signaling purposes ... Andrew PJ, Mayer B (Aug 1999). "Enzymatic function of nitric oxide synthases". (review). Cardiovascular Research. 43 (3): 521- ... It is a precursor for the synthesis of nitric oxide (NO), making it important in the regulation of blood pressure. Arginine's ... It is the precursor for the biosynthesis of nitric oxide. In humans, arginine is classified as a semiessential or conditionally ...
*  NOS1
Nitric oxide synthases (EC 1.14.13.39) (NOSs) are a family of synthases that catalyze the production of nitric oxide (NO) from ... NOS1 Nitric oxide synthase 1 (neuronal)". Grasemann H, Yandava CN, Drazen JM (December 1999). "Neuronal NO synthase (NOS1) is a ... Nitric oxide synthase 1 (neuronal), also known as NOS1, is an enzyme that in humans is encoded by the NOS1 gene. ... Leung TF, Liu EK, Tang NL, Ko FW, Li CY, Lam CW, Wong GW (October 2005). "Nitric oxide synthase polymorphisms and asthma ...
*  PIN1
"Pin1 prolyl isomerase regulates endothelial nitric oxide synthase". Arteriosclerosis, Thrombosis, and Vascular Biology. 31 (2 ...
*  Spermidine
Hu, J; Mahmoud, MI; El-Fakahany, EE (1994). "Polyamines inhibit nitric oxide synthase in rat cerebellum". Neuroscience Letters ... Inhibits neuronal nitric oxide synthase (nNOS) Binds and precipitates DNA Polyamine plant growth regulator Good dietary sources ... which has been associated with nitric oxide synthase (NOS) and cGMP/PKG pathway activation and a decrease of Na+,K+-ATPase ... Spermidine synthase (SPDS) catalyzes the formation of spermidine from putrescine. Spermidine is a precursor to further ...
*  NOSIP
Nitric oxide synthase-interacting protein is an enzyme that in humans is encoded by the NOSIP gene. GRCh38: Ensembl release 89 ... "Entrez Gene: NOSIP nitric oxide synthase interacting protein". Schleicher M, Brundin F, Gross S, et al. (2005). "Cell cycle- ... 2005). "Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity ... a novel modulator of endothelial nitric oxide synthase activity". FASEB J. 15 (1): 79-89. doi:10.1096/fj.00-0078com. PMID ...
*  Heme
Alderton, W.K. (2001). "Nitric oxide synthases: structure, function and inhibition". Biochem. J. 357 (3): 593-615. doi:10.1042/ ... and endothelial nitric oxide synthase. The word heme is derived from Greek αἷμα haima meaning blood. Hemoproteins have diverse ... synthase 1 ALAS2: aminolevulinate, δ-, synthase 2 (deficiency causes sideroblastic/hypochromic anemia) CPOX: coproporphyrinogen ... Hegg, Eric L. (2004). "Heme A Synthase Does Not Incorporate Molecular Oxygen into the Formyl Group of Heme A". Biochemistry. 43 ...
*  Hans-Joachim Schäfers
GATA5 and endothelial nitric oxide synthase expression in the ascending aorta is related to aortic size and valve morphology. ... Endothelial nitric oxide synthase in bicuspid aortic valve disease. Ann Thorac Surg. 2007; 83:1290-4 Henn D, Perttunen H, Gauer ...
*  Methylarginine
N-Methylarginine is an inhibitor of nitric oxide synthase. Chemically, it is a methyl derivative of the amino acid arginine. It ... and other endogenous nitric oxide synthase (NOS) inhibitors as an important cause of vascular insulin resistance". Hormone and ... an inhibitor of nitric oxide synthase, suppresses the development of adjuvant arthritis in rats". Arthritis & Rheumatology. 37 ... is used as a biochemical tool in the study of physiological role of nitric oxide. The inhibiting effect of N-methylarginine on ...
*  7-Nitroindazole
Babbedge RC; Bland-Ward PA; Hart SL; Moore PK (September 1993). "Inhibition of rat cerebellar nitric oxide synthase by 7-nitro ... converts arginine to citrulline and nitric oxide (NO). Nitric oxide can diffuse through the plasma membrane into neighbouring ... which is activated by nitric oxide produced by eNOS tetrahydrobiopterin, cofactor to several enzymes including nitric oxide ... Moore PK; Babbedge RC; Wallace P; Gaffen ZA; Hart SL (February 1993). "7-Nitro indazole, an inhibitor of nitric oxide synthase ...
*  Michael Palese
"Alternatively spliced neuronal nitric oxide synthase mediates penile erection. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9): ... Musicki, B; Palese, MA; Crone, JK; Burnett, AL (February 2004). "Phosphorylated endothelial nitric oxide synthase mediates ... "Akt-dependent phosphorylation of endothelial nitric-oxide synthase mediates penile erection". Proc Natl Acad Sci USA. 99 (6): ...
*  S-Nitrosothiol
Nitric oxide synthase (NOS) activity leads directly to SNO formation. NOSs are hemoproteins that combine reductase and ... Wang, P. G.; Xian, M.; Tang, X.; Wu, X.; Wen, Z.; Cai, T.; Janczuk, A. J. (2002). "Nitric Oxide Donors: Chemical Activities and ... Ernst van Faassen; Anatoly Fyodorovich Vanin (7 May 2007). Radicals for life: the various forms of nitric oxide. Elsevier. pp. ... S-Nitrosated proteins (SNOs) serve to transmit nitric oxide (NO) bioactivity and to regulate protein function through ...
*  Pimagedine
... is a diamine oxidase and nitric oxide synthase inhibitor. It acts to reduce levels of advanced glycation end ...
*  N-Acetylserotonin
NAS has also been observed to inhibit nitric oxide synthase. NAS has been reported to have anti-inflammatory effects. NAS has ... "Inhibition by N-acetyl-5-hydroxytryptamine of nitric oxide synthase expression in cultured cells and in the anaesthetized rat ...
*  PTGS1
"Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation". Proceedings of the National Academy of ... Cyclooxygenase 1 (COX-1), also known as prostaglandin G/H synthase 1, prostaglandin-endoperoxide synthase 1 or prostaglandin H2 ... "Entrez Gene: PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)". Chandrasekharan NV, ... human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and ...
*  Pseudo-nitzschia
P. multistriata was found to uniquely encode nitric oxide synthase. Pseudo-nitzschia species can be found in coastal regions ... Sequencing of Three Pseudo-nitzschia Species Reveals Comparable Gene Sets and the Presence of Nitric Oxide Synthase Genes in ...
*  N-myristoyltransferase 1
Liu J, Sessa WC (1994). "Identification of covalently bound amino-terminal myristic acid in endothelial nitric oxide synthase ...