*  Nicotinic agonist
Other nicotinic agonists, albeit generally with limited clinical use, include: lobeline, an agonist on Ganglion type nicotinic ... Agonist Muscarinic acetylcholine receptor Muscarinic agonist Muscarinic antagonist Nicotinic acetylcholine receptor Nicotinic ... "An improved nicotinic pharmacophore and a stereoselective CoMFA-model for nicotinic agonists acting at the central nicotinic ... A nicotinic agonist is a drug that mimics the action of acetylcholine (ACh) at nicotinic acetylcholine receptors (nAChRs). The ...
*  Depolarization
Examples include the nicotinic agonists suxamethonium and decamethonium. Zuckerman, Marvin (1991-05-31). Psychobiology of ...
*  Nicotinic antagonist
Nicotinic acetylcholine receptor Nicotinic agonist Muscarinic acetylcholine receptor Muscarinic agonist Muscarinic antagonist P ... A nicotinic antagonist is a type of anticholinergic drug that inhibits the action of acetylcholine (ACh) at nicotinic ... Succinylcholine is a nicotinic agonist. See neuromuscular blocking agents page for details on the mechanism of action. ... ISBN 0-443-07145-4. Page 149 Nicotinic antagonists at the US National Library of Medicine Medical Subject Headings (MeSH). ...
*  Epibatidine
... , a potent analgetic and nicotinic agonist, Molecular Pharmacology 1994; 45: 563-569 Sihver, Acta (2002). " ... Pharmacological Properties of a Novel Nicotinic Acetylcholine Receptor Agonist and Analgesic Agent". CNS Drug Reviews. 2 (1): ... Nicotinic acetylcholine receptors are found in the post-synaptic membranes of nerve cells. They propagate neurotransmission in ... The paralytic property of epibatidine takes place after its binding to muscle-type nicotinic receptors. Low doses of ...
*  Pfizer
Chantix/Champix (varenicline) for Nicotinic agonists, and anti nicotine drugs. Cefobid a cephalosporin antibiotic. Cyklokapron ...
*  David Colquhoun
Gardner, P.; Ogden, D. C.; Colquhoun, D. (1984). "Conductances of single ion channels opened by nicotinic agonists are ... The actual shut-open conformation change turned out to be much the same for partial agonists as it was for full agonists. In ... 2008) found that partial agonists were partial, not, as had been supposed since 1957, because of a deficiency in the open ... Lape, R.; Colquhoun, D.; Sivilotti, L. G. (2008). "On the nature of partial agonism in the nicotinic receptor superfamily". ...
*  Muscarine
Muscarinic agonists activate muscarinic receptors while nicotinic agonists activate nicotine receptors. Both are direct-acting ... Muscarinic agonists are used as drugs in treating glaucoma, postoperative ileus, congenital megacolon, urinary retention and ... Inocybe and Clitocybe contain muscarine concentrations up to 1.6%. Muscarine is a nonselective agonist of the muscarinic ... Most agonists for muscarine receptors are not selective for subtypes. A paucity of research exists on the metabolism of ...
*  Enopla
Also, many nemerteans produce toxins of which some are nicotinic agonists. Some of these toxins, originally found in a ...
*  GTS-21
... (DMBX-A) is a derivative of the natural product anabaseine that acts as a partial agonist at neural nicotinic ... Initial Phase 2 Trial of a Nicotinic Agonist in Schizophrenia. American Journal of Psychiatry. 2008 Apr 1. [Epub ahead of print ... PMID 12769624 Martin LF, Kem WR, Freedman R. Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of ... PMID 15155135 Simosky JK, Stevens KE, Freedman R. Nicotinic agonists and psychosis. Current Drug Targets. CNS and Neurological ...
*  Phantasmidine
It is a nicotinic agonist, meaning it binds to nicotinic receptors in the body and mimics the effects of the neurotransmitter ... as they would block nAChR to prevent the acetycholine agonist from binding to the acetylcholine receptors. Nicotinic agonists ... 24 October 2013). "Nicotinic Acetylcholine Receptor Agonists". United States Patent Application Publication. 1 (12/583,420): 1- ... 336-337). Phantasmidine is a nicotinic agonist that acts at acetylcholine receptors. It mimics the effects of acetylcholine on ...
*  AR-R17779
... is a drug that acts as a potent and selective full agonist for the α7 subtype of neural nicotinic acetylcholine ... Levin, E. D.; Bettegowda, C.; Blosser, J.; Gordon, J. (1999). "AR-R17779, and alpha7 nicotinic agonist, improves learning and ... is a highly selective full agonist at the alpha 7 nicotinic acetylcholine receptor". Journal of Medicinal Chemistry. 43 (22): ... a conformationally restricted analogue of acetylcholine that is a potent and selective alpha7 nicotinic receptor agonist". The ...
*  Sonogashira coupling
Altinicline is a nicotinic acetylcholine receptor agonist that has shown potential in the treatment of Parkinson's disease, ... 3.0.CO;2-G. Parkinson Study, Group (14 February 2006). "Randomized placebo-controlled study of the nicotinic agonist SIB-1508Y ... "A Practical and Efficient Synthesis of the Selective Neuronal Acetylcholine-Gated Ion Channel Agonist (S)-(−)-5-Ethynyl-3-(1- ...
*  Altinicline
... (SIB-1508Y, SIB-1765F) is a drug which acts as an agonist at neural nicotinic acetylcholine receptors with high ... Randomized placebo-controlled study of the nicotinic agonist SIB-1508Y in Parkinson disease. Neurology. 2006;66:408-410. doi: ... a novel nicotinic acetylcholine receptor agonist". Brain Research. 1234: 16-24. doi:10.1016/j.brainres.2008.07.063. PMID ... agonist". Pharmaceutica acta Helvetiae. 74 (2-3): 125-130. doi:10.1016/S0031-6865(99)00024-2. PMID 10812948. Wagner, F.; Comins ...
*  Muscarinic antagonist
Anticholinergic Muscarinic agonist Nicotinic acetylcholine receptor Nicotinic agonist Nicotinic antagonist Parasympatholytic ... Acetylcholine receptors are classified into two groups based on this: muscarinic, which respond to muscarine nicotinic, which ... Muscarinic antagonist effects and muscarinic agonist effects counterbalance each other for homeostasis. Certain substances are ...
*  Cys-loop receptor
Ion channel Nicotinic agonists Receptor (biochemistry) Tasneem A, Iyer L, Jakobsson E, Aravind L (2004). "Identification of the ... October 19, 2005). "Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding ... Once the agonist binds it brings about conformational changes (including moving a beta sheet of the amino-terminal domain, and ... It has been shown in recent literature that the Trp residue on loop B is crucial for both agonist and antagonist binding. The ...
*  Anabaena circinalis
Anatoxin-a functions as a postsynaptic nicotinic agonist, binding to acetylcholine receptors at the neuromuscular junctions. ...
*  Methyllycaconitine
"Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and ... Most recently, it has become an important molecular probe for studying the pharmacology of the nicotinic acetylcholine receptor ... Such properties are characteristic of an antagonist of acetylcholine exerting its effects at nicotinic, but not muscarinic ... These workers also reported that MLA displaced125I-α-bungarotoxin from purified Torpedo (electric ray) nicotinic acetylcholine ...
*  Lobeline
Farook, J. M.; Lewis, B; Gaddis, J. G.; Littleton, J. M.; Barron, S (2009). "Lobeline, a nicotinic partial agonist attenuates ... It also inhibits the reuptake of dopamine and serotonin, and acts as a mixed agonist-antagonist at nicotinic acetylcholine ... "Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and ... Damaj, M. I.; Patrick, G. S.; Creasy, K. R.; Martin, B. R. (1997). "Pharmacology of lobeline, a nicotinic receptor ligand". The ...
*  ABT-418
It acts as an agonist at neural nicotinic acetylcholine receptors, subtype-selective binding with high affinity to the α4β2, α7 ... Wilens TE, Decker MW (October 2007). "Neuronal nicotinic receptor agonists for the treatment of attention-deficit/hyperactivity ... nicotinic agonist) ABT-418 in Alzheimer's disease". Psychopharmacology. 142 (4): 334-342. doi:10.1007/s002130050897. PMID ... mature monkeys after intramuscular or transdermal administration of the CNS nicotinic receptor agonist ABT-418". ...
*  Alpha-7 nicotinic receptor
An α7 nicotinic agonist appears to have positive effects on neurocognition in persons with schizophrenia. Both α4β2 and α7 ... α7 subtype preferring blocker α3β2-Nicotinic receptor α3β4-Nicotinic receptor α4β2-Nicotinic receptor RIC3, a chaperone protein ... 2001). "The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist". ... The alpha-7 nicotinic receptor, also known as the α7 receptor, is a type of nicotinic acetylcholine receptor implicated in long ...
*  Arecoline
Owing to its muscarinic and nicotinic agonist properties, arecoline has shown improvement in the learning ability of healthy ... Arecoline is known to be a partial agonist of muscarinic acetylcholine M1, M2, M3 receptors and M4, which is believed to be the ... Arecoline (/əˈrɛkəliːn/) is a nicotinic acid-based alkaloid found in the areca nut, the fruit of the areca palm (Areca catechu ... Arecoline has been compared to nicotine; however, nicotine acts primarily on the nicotinic acetylcholine receptor. ...
*  Lobelia tupa
... a nicotinic agonist. The Mapuche Indians of Southern Chile consider it a sacred plant. Tupa leaves have also been found to ...
*  UB-165
... is a drug which acts as an agonist at neuronal nicotinic acetylcholine receptors being a full agonist of the α3β2 ... a novel nicotinic agonist with subtype selectivity implicates the alpha4beta2* subtype in the modulation of dopamine release ... "Synthesis of two fluoro analogues of the nicotinic acetylcholine receptor agonist UB-165". The Journal of Organic Chemistry. 68 ... "Synthesis and pharmacological characterization of novel analogues of the nicotinic acetylcholine receptor agonist (+/-)-UB-165 ...
*  Muscarinic acetylcholine receptor
Muscarinic agonist Muscarinic antagonist Nicotinic acetylcholine receptor Nicotinic agonist Nicotinic antagonist Eglen RM (July ... By contrast, nicotinic receptors use a ligand-gated ion channel mechanism for signaling. In this case, binding of the ligands ... Nicotinic receptors on the postganglionic neuron are responsible for the initial fast depolarization (Fast EPSP) of that neuron ... Also, only when bound with an agonist, those G proteins normally sensitive to PTX also become susceptible to CTX. The various G ...
*  University of California, San Diego Performance-Based Skills Assessment
Haig, G.; Wang, D.; Othman, A.A.; Zhao, J. (June 2016). "The α7 Nicotinic Agonist ABT-126 in the Treatment of Cognitive ...
*  Pre-Bötzinger complex
Several synthetic compounds have been shown to act on neurons specific to the preBötC, most being selective agonists or ... The suppression of muscarinic receptors and the activation of nicotinic receptors due to prenatal exposure to nicotine have ... An adenosine A1 receptor agonist has been shown to depress preBötC rhythmogenesis independent of the neurotransmitters GABA and ... Acetylcholine plays an important modulatory role on the respiratory system by altering nicotinic and muscarinic receptors. ...