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*  NF-kappa-B-activating protein
... is a protein that in humans is encoded by the NKAP gene. GRCh38: Ensembl release 89: ... "Entrez Gene: NKAP NF-kappaB activating protein". Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial ... Zhande R, Karsan A (2007). "Erythropoietin promotes survival of primary human endothelial cells through PI3K-dependent, NF- ... 2004). "Inverse correlation between p16INK4A expression and NF-kappaB activation in melanoma progression". Hum. Pathol. 35 (8 ...
*  TRAF3IP2
Li X, Commane M, Nie H, Hua X, Chatterjee-Kishore M, Wald D, Haag M, Stark GR (Oct 2000). "Act1, an NF-kappa B-activating ... Qian Y, Zhao Z, Jiang Z, Li X (2002). "Role of NF kappa B activator Act1 in CD40-mediated signaling in epithelial cells". Proc ... 2002). "Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon ... This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor ...
*  CASP8AP2
"FLASH coordinates NF-kappa B activity via TRAF2". J. Biol. Chem. 276 (27): 25073-7. doi:10.1074/jbc.M102941200. PMID 11340079. ... "FLASH coordinates NF-kappa B activity via TRAF2". J. Biol. Chem. 276 (27): 25073-7. doi:10.1074/jbc.M102941200. PMID 11340079. ... "Role of FLASH in caspase-8-mediated activation of NF-kappaB: dominant-negative function of FLASH mutant in NF-kappaB signaling ...
*  TRAF2
"FLASH coordinates NF-kappa B activity via TRAF2". J. Biol. Chem. 276 (27): 25073-7. doi:10.1074/jbc.M102941200. PMID 11340079. ... "Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death". J. ... "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97-105. ... activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase ...
*  MTPN
Sivasubramanian N, Adhikary G, Sil PC, Sen S (1996). "Cardiac myotrophin exhibits rel/NF-kappa B interacting activity in vitro ... 2002). "Myotrophin/V-1, a protein up-regulated in the failing human heart and in postnatal cerebellum, converts NFkappa B p50- ... converts NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers". J. Biol. Chem. United States. 277 (26): 23888-97. ...
*  Rel homology domain
PDB: 1SVC​;Müller CW, Rey FA, Sodeoka M, Verdine GL, Harrison SC (January 1995). "Structure of the NF-kappa B p50 homodimer ... The Rel homology domain (RHD) is a protein domain found in a family of eukaryotic transcription factors, which includes NF-κB, ... element-specific transcriptional activity of differentially phosphorylated nuclear factor-kappa B". J. Biol. Chem. 280 (1): 244 ...
*  Bharat Aggarwal
"Patent number 5,891,924 -- Curcumin (diferuloylmethane) inhibition of NF.kappa.B activation. Inventor: Bharat B. Aggarwal ( ... In 1996, Aggarwal patented curcumin as an inhibitor of NF-κB activation, and he co-founded a company in 2004 called Curry ...
*  PPARGC1A
Akt and calcineurin are both activators of NF kappa B (p65). Through their activation PGC-1α seems to activate NF kappa B. ... Other groups found that PGC-1s inhibit NF kappa B activity. The effect was demonstrated for PGC-1 alpha and beta. PGC-1α has ... Increased activity of NF kappa B in muscle has recently been demonstrated following induction of PGC-1α. The finding seems to ... Viatour P, Merville MP, Bours V, Chariot A (January 2005). "Phosphorylation of NF-kappaB and IkappaB proteins: implications in ...
*  RELA
Scheinman RI, Beg AA, Baldwin AS (Oct 1993). "NF-kappa B p100 (Lyt-10) is a component of H2TF1 and can function as an I kappa B ... Baldwin AS (1996). "The NF-kappa B and I kappa B proteins: new discoveries and insights". Annual Review of Immunology. 14: 649- ... "DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide". Cell. 64 (5): 961-9. ... newly synthesized I kappa B beta in persistent activation of NF-kappa B". Molecular and Cellular Biology. 16 (10): 5444-9. doi: ...
*  HIV disease progression rates
Baeuerle, P.A. (1991). "The inducible transcription activator NF-kappa B: regulation by distinct protein subunits". Biochimica ... release IFN-alpha which acts on an autocrine and paracrine loop that up-regulates the levels of physiologically active NF-kappa ...
*  NFKB2
Scheinman RI, Beg AA, Baldwin AS (Oct 1993). "NF-kappa B p100 (Lyt-10) is a component of H2TF1 and can function as an I kappa B ... Baldwin AS (1996). "The NF-kappa B and I kappa B proteins: new discoveries and insights". Annual Review of Immunology. 14 (1): ... Nuclear factor NF-kappa-B p100 subunit is a protein that in humans is encoded by the NFKB2 gene. NFKB has been detected in ... Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, ...
*  AKT1
"Complex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation ... "Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription". Mol. Cell. Biol. 22 ... Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB (Sep 1999). "NF-kappaB activation by tumour necrosis factor ... Romashkova JA, Makarov SS (Sep 1999). "NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling". Nature. 401 (6748): 86- ...
*  MAP3K8
"ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability". Molecular and ... "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nature Cell Biology. 6 (2): 97- ... "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nature Cell Biology. 6 (2): 97- ... "Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription". Molecular and ...
*  Interleukin-12 subunit beta
"Regulation of interleukin 12 p40 expression through an NF-kappa B half-site". Mol. Cell. Biol. 15 (10): 5258-67. PMC 230773 . ...
*  Minocycline
... through blockade of NF-kappa B nuclear translocation.[citation needed] A 2007 study reported the impact of the antibiotic ...
*  IκBα
Verma IM, Stevenson JK, Schwarz EM, Van Antwerp D, Miyamoto S (1995). "Rel/NF-kappa B/I kappa B family: intimate tales of ... "Control of NF-kappa B transcriptional activation by signal induced proteolysis of I kappa B alpha". Philos. Trans. R. Soc. Lond ... Prigent M, Barlat I, Langen H, Dargemont C (November 2000). "IkappaBalpha and IkappaBalpha /NF-kappa B complexes are retained ... IκBα inhibits NF-κB by masking the nuclear localization signals (NLS) of NF-κB proteins and keeping them sequestered in an ...
*  NFKBID
"Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor". Mol. Cell. 9 (3): 637-48 ... After NF-κB activation atypical IκBs are induced by the transcription factor Atypical IκBs, in turn, can regulate the NF-κB ... IκBNS is a member of the atypical inhibitors of NF-κB (also called the nuclear IκBs). NF-κB is a transcription factor, which ... Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta also known as IκBNS is a protein in humans ...
*  Heat shock protein 90kDa alpha (cytosolic), member A1
"The activity of hsp90 alpha promoter is regulated by NF-kappa B transcription factors". Oncogene. 27 (8): 1175-8. doi:10.1038/ ... NF-κB or RELA also induces HSP90AA1 expression possibly explaining the pro-survival ability of NF-κB-driven transcription. ... Hu Y, Mivechi NF (May 2003). "HSF-1 interacts with Ral-binding protein 1 in a stress-responsive, multiprotein complex with ... Bohonowych JE, Hance MW, Nolan KD, Defee M, Parsons CH, Isaacs JS (Apr 2014). "Extracellular Hsp90 mediates an NF-κB dependent ...
*  PYCARD
... a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B". J. Biol. Chem. 277 (13 ... "ASC is an activating adaptor for NF-kappa B and caspase-8-dependent apoptosis". Biochem. Biophys. Res. Commun. 303 (1): 69-73. ... a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing ... "The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation". ...
*  HIVEP2
Rustgi AK, Van 't Veer LJ, Bernards R (November 1990). "Two genes encode factors with NF-kappa B- and H2TF1-like DNA-binding ... These proteins bind specific DNA sequences, including the kappa-B motif (GGGACTTTCC), in the promoters and enhancer regions of ...
*  NFRKB
Urban MB, Schreck R, Baeuerle PA (1991). "NF-kappa B contacts DNA by a heterodimer of the p50 and p65 subunit". EMBO J. 10 (7 ... Nuclear factor related to kappa-B-binding protein is a protein that in humans is encoded by the NFRKB gene. GRCh38: Ensembl ... Adams BS, Leung KY, Hanley EW, Nabel GJ (1992). "Cloning of R kappa B, a novel DNA-binding protein that recognizes the ... "Localization of the gene encoding R kappa B (NFRKB), a tissue-specific DNA binding protein, to chromosome 11q24-q25". Genomics ...
*  RELB
"A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site". ... Taylor JP, Pomerantz RJ, Oakes JW, Khalili K, Amini S (Jan 1995). "A CNS-enriched factor that binds to NF-kappa B and is ... Liu J, Perkins ND, Schmid RM, Nabel GJ (Jun 1992). "Specific NF-kappa B subunits act in concert with Tat to stimulate human ... "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nature Cell Biology. 6 (2): 97- ...
*  IKBKG
NF-kappa-B essential modulator (NEMO) also known as inhibitor of nuclear factor kappa-B kinase subunit gamma (IKK-γ) is a ... Li X, Commane M, Nie H, Hua X, Chatterjee-Kishore M, Wald D, Haag M, Stark GR (September 2000). "Act1, an NF-kappa B-activating ... Li X, Commane M, Nie H, Hua X, Chatterjee-Kishore M, Wald D, Haag M, Stark GR (September 2000). "Act1, an NF-kappa B-activating ... Shifera AS, Horwitz MS (March 2008). "Mutations in the zinc finger domain of IKK gamma block the activation of NF-kappa B and ...
*  HIVEP3
Rustgi AK, Van 't Veer LJ, Bernards R (Nov 1990). "Two genes encode factors with NF-kappa B- and H2TF1-like DNA-binding ... Bettelli E, Dastrange M, Oukka M (Apr 2005). "Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to ... These proteins bind specific DNA sequences, including the kappa-B motif (GGGACTTTCC), in the promoters and enhancer regions of ...
*  Mothers against decapentaplegic homolog 7
"A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA". Genes Dev. 14 (2): 187-97. doi:10.1101/gad.14.2.187 ... The interaction blocks the formation of the IRAK1-mediated IL-1R/TLR signaling complex therefore abrogates NF-κB activity, ...
*  Zymosan
2003). "Direct binding of Toll-like receptor 2 to zymosan, and zymosan-induced NF-kappa B activation and TNF-alpha secretion ...