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*  Neutrophil cytosolic factor 4
... has been shown to interact with Ku70, Neutrophil cytosolic factor 1 and Moesin. ENSG00000100365 ... It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 ... Neutrophil cytosol factor 4 is a protein that in humans is encoded by the NCF4 gene. The protein encoded by this gene is a ... "Entrez Gene: NCF4 neutrophil cytosolic factor 4, 40kDa". Muise AM, Xu W, Guo CH, Walters TD, Wolters VM, Fattouh R, Lam GY, Hu ...
*  Neutrophil cytosolic factor 2
Neutrophil cytosol factor 2 is a protein that in humans is encoded by the NCF2 gene. This gene encodes neutrophil cytosolic ... This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene ... 1990). "Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src". Science. 248 (4956 ... Dusi S, Rossi F (1994). "Activation of NADPH oxidase of human neutrophils involves the phosphorylation and the translocation of ...
*  Neutrophil swarming
... is a specific type of neutrophil migration behaviour characterised by a high coordination between ... neutrophils, clustering of neutrophils to the inflammation site and signalling to other neutrophils further away. This specific ... Tan, Sioh-Yang; Weninger, Wolfgang (February 2017). "Neutrophil migration in inflammation: intercellular signal relay and ... "Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo". Nature. 498 (7454): 371-375. doi:10.1038/ ...
*  Cathepsin G
Brandt E, Van Damme J, Flad HD (July 1991). "Neutrophils can generate their activator neutrophil-activating peptide 2 by ... such as neutrophil elastase and the granzymes. As a neutrophil serine protease, was first identified as degradative enzyme that ... "Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus ... It localizes to Neutrophil extracellular traps (NETs), via its high affinity for DNA, an unusual property for serine proteases ...
*  Neutrophil Oxidative Index
Neutrophil Oxidative Burst Test (or Chronic Granulomatous Disease (CGD) Test) is a measure of neutrophil oxidation is a useful ... From total blood, neutrophils can be purified and the NADPH oxidase activity can be measured with different methods in these ... Neutrophil respiratory burst in term and preterm neonates without signs of infection and in those with increased levels of C- ... In the Neutrophil Oxidative Burst Test heparinized whole blood is incubated at 37 °C with phorbol myristate acetate (PMA), a ...
*  Neutrophil extracellular traps
... (NETs) are networks of extracellular fibers, primarily composed of DNA from neutrophils, which ... NETs allow neutrophils to kill extracellular pathogens while minimizing damage to the host cells. Upon in vitro activation with ... Neutrophils are the immune system's first-line of defense against infection and have conventionally been thought to kill ... Platelet-induced NET formation occurs very rapidly (in minutes) and may or may not result in death of the neutrophils. NETs ...
*  Formyl peptide receptor 1
Thomas KM, Pyun HY, Navarro J (Nov 1990). "Molecular cloning of the fMet-Leu-Phe receptor from neutrophils". The Journal of ... FPR1 is widely expressed by circulating blood neutrophils, eosinophils, basophils, monocytes, and platelets; tissue-bound ... is a neutrophil chemotactic factor that operates through receptors whose genes cluster with those for the three formly peptide ... C3a is a neutrophil chemotactic factor which operates through a G protein coupled chemotactic factor receptor, the C3a receptor ...
*  Chronic granulomatous disease
... neutrophils and macrophages) require an enzyme to produce reactive oxygen species to destroy bacteria after they are ingested ( ... clearing pre-existing infections and demonstrating increased oxidase activity in their neutrophils. However, long-term ...
*  Neutrophil
Neutrophils may be subdivided into segmented neutrophils and banded neutrophils (or bands). They form part of the ... Neutrophils from women exhibit a small additional X chromosome structure, known as a "neutrophil drumstick". Neutrophils will ... Normally, neutrophils contain a nucleus divided into 2-5 lobes. Neutrophils are a type of phagocyte and are normally found in ... Decreases in neutrophil function have been linked to hyperglycemia. Dysfunction in the neutrophil biochemical pathway ...
*  Hypersegmented neutrophil
Normally, the number of segments in the nucleus of a neutrophil increases as it matures and ages after the neutrophil is ... Although normal neutrophils only contain three or four nuclear lobes (the "segments"), hypersegmented neutrophils contain six ... Because of the short life-span of neutrophils, these abnormal hypersegmented neutrophils characteristically appear even before ... A hypersegmented neutrophil is a clinical laboratory finding. It is visualized by drawing blood from a patient and viewing the ...
*  Neutrophil elastase
The gene encoding neutrophil elastase, ELA2, consists of five exons. Neutrophil elastase is closely related to other cytotoxic ... There appear to be two forms of neutrophil elastase, termed IIa and IIb. In humans, neutrophil elastase is encoded by the ELANE ... Neutrophil elastase (EC 3.4.21.37, leukocyte elastase, ELANE, ELA2, elastase 2, neutrophil, elaszym, serine elastase, subtype ... Neutrophil elastase hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins ...
*  Neutrophil collagenase
... (EC 3.4.24.34, matrix metalloproteinase 8, PMNL collagenase, MMP-8) is an enzyme. This enzyme catalyses ... Neutrophil collagenase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular Biology ... Human Neutrophil Collagenase. A distinct gene product with homology to other matrix metalloproteinases". J. Biol. Chem. 265 (20 ... The collagen substrate specificity of human neutrophil collagenase". J. Biol. Chem. 262 (21): 10048-10052. PMID 3038863. Hasty ...
*  Absolute neutrophil count
... (ANC) is a measure of the number of neutrophil granulocytes (also known as polymorphonuclear cells, ... PMN's, polys, granulocytes, segmented neutrophils or segs) present in the blood. Neutrophils are a type of white blood cell ... This is known as the "I/T ratio". Al-Gwaiz LA, Babay HH (2007). "The diagnostic value of absolute neutrophil count, band count ... Russell GA, Smyth A, Cooke RW (July 1992). "Receiver operating characteristic curves for comparison of serial neutrophil band ...
*  Neutrophil immunodeficiency syndrome
... is a condition caused by mutations in the Rac2 gene. Immunodeficiency with hyper-IgM List ...
*  Neutrophil-specific granule deficiency
... however a lack of defensins and lactoferrin drastically weakens the neutrophil innate ability to fight infection. Neutrophils ... Neutrophils and eosinophils will contain hyposegmented nuclei (a pseudo-Pelger-Huet anomaly). A majority of patients with SGD ... The defect in CEBPE appears to block the ability of neutrophils to mature past the promyelocyte stage in bone marrow. Since ... Neutrophil-specific granule deficiency (SGD, previously known as lactoferrin deficiency) is a rare congenital immunodeficiency ...
*  Anti-neutrophil cytoplasmic antibody
1990). "Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro". ... Furthermore, neutrophils release chemoattractive signalling molecules that recruit more neutrophils to the endothelium, acting ... Immunofluorescence (IF) on ethanol-fixed neutrophils is used to detect ANCA, although formalin-fixed neutrophils may be used to ... whereby activated neutrophils and ANCA-reactive B-cells engage in intercellular cross-talk, which leads not only to neutrophil ...
*  Neutrophil cytosolic factor 1
... has been shown to interact with: Moesin, Neutrophil cytosolic factor 4, and RELA. GRCh38: Ensembl ... Neutrophil cytosol factor 1, also known as p47phox, is a protein that in humans is encoded by the NCF1 gene. The protein ... Volpp BD, Nauseef WM, Clark RA (1988). "Two cytosolic neutrophil oxidase components absent in autosomal chronic granulomatous ... NCF1 neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1)". "Study of complex genetic region finds ...
*  Neutrophil to lymphocyte ratio
Wang J (Jan 2014). "The clinical significance of tumor-infiltrating neutrophils and neutrophil-to-CD8+lymphocyte ratio in ... In medicine neutrophil to lymphocyte ratio (NLR) is used as a marker of subclinical inflammation. It is calculated by dividing ... Wang X (Mar 2014). "Neutrophil to lymphocyte ratio in relation to risk of all-cause mortality and cardiovascular events among ... Xue P (Apr 2014). "Neutrophil-to-lymphocyte ratio for predicting palliative chemotherapy outcomes in advanced pancreatic cancer ...
*  Nonspecific immune cell
This process characterizes neutrophils as a type of phagocyte. Neutrophils contain neutrophil extracellular traps (NETs), ... Neutrophils are a type of phagocyte, abundant in blood, that phagocytize pathogens in acute inflammation. Neutrophils, along ... After stimulation of the neutrophil response, neutrophils lose their shape, allowing euchromatin and heterochromatin to ... Neutrophils are some of the first immune cells to travel to sites of infection that aid in fighting infection by ingesting ...
*  Pearson syndrome
Neutrophils 2. Pancreas. Pearson Syndrome causes the exocrine pancreas to not function properly because of scarring and atrophy ... With Pearson Syndrome, the bone marrow fails to produce white blood cells called neutrophils. The syndrome also leads to anemia ...
*  Oxidative stress
Segal, AW (2005). "How neutrophils kill microbes". Annu Rev Immunol. 23 (5): 197-223. doi:10.1146/annurev.immunol.23.021704. ... platelets and polymorphonuclear neutrophils of patients with sickle cell disease exhibit oxidative stress that can be ...
*  C5a receptor
Sengeløv H (1996). "Complement receptors in neutrophils". Critical Reviews in Immunology. 15 (2): 107-31. doi:10.1615/ ...
*  MMP3
Neutrophils carry MMP-9., which has also been shown to degrade occludin. This leads to further disruption of the BBB and BSCB ... The increase in blood-brain barrier and blood-spinal cord barrier permeability allows for more neutrophils to infiltrate the ... Gurney KJ, Estrada EY, Rosenberg GA (Jul 2006). "Blood-brain barrier disruption by stromelysin-1 facilitates neutrophil ... "Neutrophils mediate blood-spinal cord barrier disruption in demyelinating neuroinflammatory diseases". Journal of Immunology. ...
*  Neutrophilia
... is leukocytosis of neutrophils, that is, a high number of neutrophil granulocytes in the blood. Neutrophils are the primary ... A "left shift" refers to the presence of increased proportions of younger, less well differentiated neutrophils and neutrophil- ... Granulocytosis (often used as synonym) Neutropenia (having too few neutrophils) Absolute neutrophil count "neutrophilia" at ... Neutrophils are also increased in any acute inflammation, so will be raised after a heart attack, other infarct or burns. Some ...
*  White blood cell
A decrease in levels of neutrophils on lab tests is due to either decreased production of neutrophils or increased removal from ... Neither dead cell debris nor attacking microorganisms can be dealt with effectively by the neutrophils. Unlike neutrophils, ... Neutrophils are the most common cell type seen in the early stages of acute inflammation. The life span of a circulating human ... Neutrophils are active in phagocytosing bacteria and are present in large amount in the pus of wounds. These cells are not able ...