In 2004, Brinkmann and colleagues described a striking observation that activation of neutrophils causes the release of web- ... Neutrophils may be subdivided into segmented neutrophils and banded neutrophils (or bands). They form part of the ... Normally, neutrophils contain a nucleus divided into 2-5 lobes. Neutrophils are a type of phagocyte and are normally found in ... Gerasimov IG, Ignatov DI (2004). "[Neutrophil activation in vitro]". Tsitologiia. 46 (2): 155-158. PMID 15174354. Gerasimov IG ...
Prieto, JA; Panyutich, AV; Heine, RP (January 1997). "Neutrophil activation in preeclampsia. Are defensins and lactoferrin ... Human neutrophil peptides are also known as α-defensins. Human neutrophil-derived alpha-defensins (HNPs) are capable of ... Initially human alpha defensin peptides were isolated from the neutrophils and are thus called human neutrophil peptides. ... Human neutrophil peptides are found in human atherosclerotic arteries, inhibit LDL metabolism and fibrinolysis and promote Lp(a ...
Lee WL, Downey GP (February 2001). "Neutrophil activation and acute lung injury". Curr Opin Crit Care. 7 (1): 1-7. doi:10.1097/ ... Neutrophils do not return to the blood; they turn into pus cells and die. Mature neutrophils are smaller than monocytes and ... Neutrophils also play a key role in the development of most forms of acute lung injury. Here, activated neutrophils release the ... Neutrophils do not normally exit the bone marrow until maturity but during an infection neutrophil precursors called ...
Knäuper V, Krämer S, Reinke H, Tschesche H (April 1990). "Characterization and activation of procollagenase from human ... Neutrophil+collagenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC 3.4.24). ... Neutrophil collagenase (EC 3.4.24.34, matrix metalloproteinase 8, PMNL collagenase, MMP-8) is an enzyme. This enzyme catalyses ... Collagenase Hasty KA, Jeffrey JJ, Hibbs MS, Welgus HG (July 1987). "The collagen substrate specificity of human neutrophil ...
"The phosphorylation of the respiratory burst oxidase component p47phox during neutrophil activation. Phosphorylation of sites ... Neutrophil cytosolic factor 1 has been shown to interact with: Moesin, Neutrophil cytosolic factor 4, and RELA. GRCh38: Ensembl ... Neutrophil cytosol factor 1, also known as p47phox, is a protein that in humans is encoded by the NCF1 gene. The protein ... Gu Y, Xu YC, Wu RF, Nwariaku FE, Souza RF, Flores SC, Terada LS (May 2003). "p47phox participates in activation of RelA in ...
EID: 2-s2.0-0022340824 Pick, Edgar (2020). "Cell-Free NADPH Oxidase Activation Assays: A Triumph of Reductionism". Neutrophil. ... Pick, Edgar (1 January 2014). "Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase". Small GTPases. 5 ( ... Bromberg, Y., and Pick, E. Activation of NADPH-dependent superoxide production in a cell-free system by sodium dodecyl sulfate ... cite book}}: ,journal= ignored (help) Pick, E.; Kroizman, T.; Abo, A. (15 December 1989). "Activation of the superoxide-forming ...
Knäuper V, Murphy G, Tschesche H (January 1996). "Activation of human neutrophil procollagenase by stromelysin 2". European ... Nakamura H, Fujii Y, Ohuchi E, Yamamoto E, Okada Y (April 1998). "Activation of the precursor of human stromelysin 2 and its ... "Activation of type IV procollagenases by human tumor-associated trypsin-2". The Journal of Biological Chemistry. 272 (34): ...
Wientjes FB, Hsuan JJ, Totty NF, Segal AW (1993). "p40phox, a third cytosolic component of the activation complex of the NADPH ... Neutrophil cytosolic factor 4 has been shown to interact with Ku70, Neutrophil cytosolic factor 1 and Moesin. ENSG00000100365 ... It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 ... Neutrophil cytosol factor 4 is a protein that in humans is encoded by the NCF4 gene. The protein encoded by this gene is a ...
Normal-density neutrophil activation correlated with MPO and PRTN3 mRNA. Increased autoantigen gene expression originating from ... The correlation between autoantigen gene expression and antibody-mediated normal-density neutrophil activation links gene ... highlights neutrophil heterogeneity where expression in normal-density neutrophils correlates with ANCA-induced activation". ... "Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro". Proceedings ...
Paulino EC, Steil AA, Jancar S (July 2006). "Effect of endothelins on human neutrophil activation by immune complexes". ... Some studies suggest that EDNRB activation by ET-2 regulates follicular rupture by antagonising effects of EDNRA stimulation. ...
... of activation. It shows a duplex role in affecting chemotaxis; while inactivating neutrophil CXCR2 receptor, generates an ... Staphopain A was shown to inhibit activation of the complement system activation by cleaving components that are part of all ... "Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis". The EMBO Journal. 31 (17): ... Staphopain A is elastinolytic to a degree fairly equal to that of neutrophil elastase, and has a very broad specificity ...
"Spatial and temporal analysis of Rac activation during live neutrophil chemotaxis". Curr. Biol. 12 (23): 2029-34. doi:10.1016/ ...
Dusi S, Rossi F (December 1993). "Activation of NADPH oxidase of human neutrophils involves the phosphorylation and the ... Neutrophil cytosol factor 2 is a protein that in humans is encoded by the NCF2 gene. This gene encodes neutrophil cytosolic ... "Entrez Gene: NCF2 neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2)". Wientjes FB, Segal AW ( ... This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene ...
Schymeinsky J, Mócsai A, Walzog B (August 2007). "Neutrophil activation via beta2 integrins (CD11/CD18): molecular mechanisms ... However, other therapies using small allosteric CD11b agonists seem to be a promising tool as their activation of CD11b leads ... Consequently, this leads to a reduced activation of NF-κB and lower production of above-mentioned pro-inflammatory cytokines. ... Beside TLR signalling, CD11b also negatively regulates B cell receptor (BCR) signalling, and it suppresses T cell activation ...
October 2016). "Treatment with the GPR55 antagonist CID16020046 increases neutrophil activation in mouse atherogenesis". ... It was found to block a number of GPR55 mediated responses such as wound healing and activation of immune system T-cells and B- ...
... neutrophil activation and intravascular bubbles following open-water scuba diving. Goldman, S (2013); An improved new class of ... neutrophil activation and intravascular bubbles following open-water scuba diving". Undersea & Hyperbaric Medicine. 112 (8): ...
... neutrophil activation, and intravascular bubbles following open-water SCUBA diving". Journal of Applied Physiology. 112 (8): ...
Dwivedi, N., & Radic, M. (2012). Neutrophil activation and B-cell stimulation in the pathogenesis of Felty's syndrome. Polskie ... In Felty's syndrome, chronic activation of neutrophils progresses to neutropenia and unabated infections. Neutropenia is a ... Neutrophils are the most abundant cells among white blood cells and play an important role in the immune system by destroying ... Inflammatory chemicals draw neutrophils to the area where they congregate and fight infection. A decrease in the number of ...
"The phosphorylation of the respiratory burst oxidase component p47phox during neutrophil activation. Phosphorylation of sites ...
Schymeinsky J, Mócsai A, Walzog B (August 2007). "Neutrophil activation via beta2 integrins (CD11/CD18): molecular mechanisms ... Several transforming viruses contain "Immunoreceptor Tyrosine Activation Motifs" (ITAMs) which lead to activation of Syk ... However, activation of SYK relies less on phosphorylation by Src family kinases than ZAP70. SYK and ZAP70 share a common ... "Differential effect of the inhibition of Grb2-SH3 interactions in platelet activation induced by thrombin and by Fc receptor ...
Schymeinsky J, Mócsai A, Walzog B (August 2007). "Neutrophil activation via beta2 integrins (CD11/CD18): molecular mechanisms ... This is especially important for neutrophils, as cellular adhesion plays a large role in extravasation from the blood vessels. ... Gahmberg CG, Fagerholm S (August 2002). "Activation of leukocyte beta2-integrins". Vox Sanguinis. 83 Suppl 1: 355-8. doi: ... neutrophils and NK cells. LFA-1 is involved in adhesion and binding to antigen presenting cells through interactions with the ...
Neutrophils are also an important component of oncomodulin activation. Without neutrophils present, macrophages are less ... This is because neutrophils enter the area of inflammation before macrophages do. In addition to macrophages, neutrophils are ... "Neutrophils Express Oncomodulin and Promote Optic Nerve Regeneration". Journal of Neuroscience. 33 (37): 14816-14824. doi: ...
... resulting in the activation of macrophages. Macrophages secrete more IL-8, propagating the neutrophil-mediated inflammatory ... recruiting neutrophils. Neutrophil recruitment results in a very rapid onset of inflammation. Therefore, co-infection with ... Macrophages may be stimulated to secrete IL-8 by the same process as is seen in the gut, causing neutrophils to accumulate at ... Neutrophils produce pus in the dermal papillae, generating characteristic blisters. IL-31 accumulation at the blisters may ...
11 May 2022). "Acute inflammatory response via neutrophil activation protects against the development of chronic pain". Science ...
"Activation of human polymorphonuclear neutrophil functions by interferon-gamma and tumor necrosis factors". Journal of ... Formation of LT-α1-β2 complex enables binding to LT-β receptors and subsequent activation of signaling pathways. Activation of ... In order for activation to occur, LT-α must form a complex with LT-β to form the LT-α1-β2 complex. ... Activation of LT-β receptors is capable of inducing cell death of cancerous cells and suppressing tumor growth. The process of ...
2002). "Protein-tyrosine phosphatase MEG2 is expressed by human neutrophils. Localization to the phagosome and activation by ...
"Activation of human neutrophils by electronically transmitted phorbol-myristate acetate". Medical Hypotheses. 54 (1): 33-39. ... Thomas, Y.; Schiff, M.; Belkadi, L.; Jurgens, P.; Kahhak, L.; Benveniste, J. (2000). "Activation of Human Eurtrophils by ...
Thomas, Y.; Schiff, M.; Belkadi, L.; Jurgens, P.; Kahhak, L.; Benveniste, J. (2000). "Activation of human neutrophils by ...
13 (A163). J. Benveniste; Thomas Y; Schiff M; Belkadi L; Jurgens P; Kahhak L (2000). "Activation of human neutrophils by ... Thomas, Y.; Schiff, M.; Belkadi, L.; Jurgens, P.; Kahhak, L.; Benveniste, J. (2000). "Activation of Human Eurtrophils by ... "Histamine dilutions modulate basophil activation". Inflammation Research. Birkhäuser Basel. 53 (5): 181-188. doi:10.1007/s00011 ...
Activation of a nerve causes lower pH in the vesicles, and a larger pH in the cell. Calcium and hydrogen antiporters are ... Neutrophils, "degranulation," and "phagocytosis" from protein kinase C increases vATPase. vATPase activity creates immune ... V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor ... response against pathogens by macrophage activation. Dendritic cells require vATPase to mature. ENSG00000234920, ...
"Caspase-catalyzed cleavage and activation of Mst1 correlates with eosinophil but not neutrophil apoptosis". Blood. 99 (9): 3432 ... In addition to activation by straurosporine and FAS ligand, STK3 has been found to be activated through dissociation of GLRX ... Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis ... This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast 'sterile 20' ( ...