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*  Neuroregeneration
Influence of insulin-like growth factor-I (IGF-I) on nerve autografts and tissue-engineered nerve grafts. Muscle Nerve. 2002;26 ... Human axon growth rates can reach 1 mm/day in small nerves and 5 mm/day in large nerves. The distal segment, however, ... The expectations after surgical repair of a divided peripheral nerve depends on several factors: Age: Recovery of a nerve after ... This is called peripheral nerve reconstruction. The injured nerve is identified and exposed so that normal nerve tissue can be ...
*  Nerve growth factor
... at the US National Library of Medicine Medical Subject Headings (MeSH) NCBI: nerve growth factor (beta ... "Human CD4+ T cell clones produce and release nerve growth factor and express high-affinity nerve growth factor receptors". The ... Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance ... by NGF Neurotrophin Neurotrophin-3 Neurotrophin-4 Nerve growth factor receptor Growth factor Brain-derived neurotrophic factor ...
*  Nerve growth factor IB
... is a member of the Nur nuclear receptor family of intracellular transcription factors. NGFIB is involved ... Nerve growth factor IB binds as a monomer or homodimer to response element NBRE and as a homodimer to NurRE. It is also capable ... The nerve growth factor IB (NGFIB) also known as Nur77 or NR4A1 (nuclear receptor subfamily 4 group A member 1) is a protein ... Nerve growth factor IB has the systematic HUGO gene symbol NR4A1. It belongs to a group of three closely related orphan ...
*  Low-affinity nerve growth factor receptor
The low-affinity nerve growth factor receptor (nerve growth factor receptor (TNFR superfamily, member 16), also called the ... Nerve growth factor, the prototypical growth factor, is a protein secreted by a neuron's target. NGF is critical for the ... nerve growth factor (NGF), brain derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). ... Low-affinity nerve growth factor receptor has been shown to interact with: FSCN1, MAGEH1, NDN, NGFRAP1 NGF, PRKACB, TRAF2, and ...
*  Neurotrophin
Nerve growth factor (NGF), the prototypical growth factor, is a protein secreted by a neuron's target cell. NGF is critical for ... nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). The term ... nerve growth factor (NGF), brain derived neurotrophic factor (BDNF), neurotrophin 3 (NT-3), and neurotrophin 4 (NT-4)' (April 4 ... Inoue S, Ikeda K, Hayashi K, Koyama J (1992). "Purification and amino-acid sequence of a nerve growth factor from the venom of ...
*  Wound licking
Nam JW, Chung JW, Kho HS, Chung SC, Kim YK (March 2007). "Nerve growth factor concentration in human saliva". Oral Dis. 13 (2 ... which will inhibit bacterial growth. Saliva contains growth factors such as epidermal growth factor, VEGF, TGF-β1, leptin, IGF- ... Li AK, Koroly MJ, Schattenkerk ME, Malt RA, Young M (July 1980). "Nerve growth factor: acceleration of the rate of wound ... Kawamoto K, Matsuda H (2004). "Nerve growth factor and wound healing". Prog. Brain Res. Progress in Brain Research. 146: 369-84 ...
*  Cholinergic neuron
... which increases the degradation of Nerve Growth Factor and reduces its production. This double failure of Nerve Growth Factor ... Nerve Growth Factor protects cholinergic neurons. The small non-toxic molecule urea has no neuroprotective effect on ... If the supply of Nerve Growth Factor is interrupted, cholinergic atrophy could begin to occur in these neurons and change their ... A pathway exists for both the maturation and degradation of Nerve Growth Factor, which causes cholinergic neurons to become ...
*  MAPK13
Sofroniew MV, Howe CL, Mobley WC (2001). "Nerve growth factor signaling, neuroprotection, and neural repair". Annu. Rev. ... Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase. ...
*  Rita Levi-Montalcini
... isolating nerve growth factor (NGF) from observations of certain cancerous tissues that cause extremely rapid growth of nerve ... Aloe, L. (1999). "Rita Levi-Montalcini: A brief biographic view of past and present studies on nerve growth factor". Microscopy ... Aloe, L. (2004). "Rita Levi-Montalcini: The discovery of nerve growth factor and modern neurobiology". Trends in Cell Biology. ... Cowan, W. M. (2001). "Viktor Hamburger Andrita Levi-Montalcini: The Path to the Discovery of Nerve Growth Factor". Annual ...
*  MAPK12
Sofroniew MV, Howe CL, Mobley WC (2001). "Nerve growth factor signaling, neuroprotection, and neural repair". Annu. Rev. ...
*  GAB2
Wu C, Lai CF, Mobley WC (August 2001). "Nerve growth factor activates persistent Rap1 signaling in endosomes". The Journal of ... Upon stimulation by growth hormone, insulin, epidermal growth factor (EFG), etc., the GAB2 protein can be recruited from the ... Hibi M, Hirano T (April 2000). "Gab-family adapter molecules in signal transduction of cytokine and growth factor receptors, ... "Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors". Blood ...
*  Fulranumab
... is a monoclonal antibody against nerve growth factor. It was designed for the treatment of pain. Johnson & Johnson ... List of investigational analgesics Monoclonal Antibodies Targeted Against Nerve Growth Factor For the Treatment of Chronic Pain ...
*  Diagonal band of Broca
Its behavior can be altered by nerve growth factor. This article incorporates text in the public domain from the 20th edition ... "Chronic exposure to nerve growth factor increases acetylcholine and glutamate release from cholinergic neurons of the rat ... This is a cholinergic bundle of nerve fibers posterior to the anterior perforated substance. It interconnects the paraterminal ...
*  CRKL
Wu C, Lai CF, Mobley WC (August 2001). "Nerve growth factor activates persistent Rap1 signaling in endosomes". The Journal of ... "Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the ... "c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination". Journal ... van Dijk TB, van Den Akker E, Amelsvoort MP, Mano H, Löwenberg B, von Lindern M (November 2000). "Stem cell factor induces ...
*  Superior cervical ganglion
SCG cells were used to study nerve growth factor (NGF) and its ability to direct growth of neurons. Results showed that NGF did ... Campenot, RB (1977). "Local control of neurite development by nerve growth factor". Proc Natl Acad Sci U S A. 74 (10): 4516-9. ... Schwartz, JP; Breakefield, XO (February 1980). "Altered nerve growth factor in fibroblasts from patients with familial ... Postganglionic fibers then leave the SCG via the internal carotid nerve and the external carotid nerve. This pathway of SCG ...
*  CCDC116
NGFRAP is a nerve growth factor receptor associated protein. This gene is believed to play a role in the pathogenesis of ...
*  RAPGEF1
Wu C, Lai CF, Mobley WC (Aug 2001). "Nerve growth factor activates persistent Rap1 signaling in endosomes". The Journal of ... "Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the ... "Identification of Tyr-762 in the platelet-derived growth factor alpha-receptor as the binding site for Crk proteins". Oncogene ... Rap guanine nucleotide exchange factor 1 is a protein that in humans is encoded by the RAPGEF1 gene. The protein encoded by ...
*  Congenital insensitivity to pain with anhidrosis
NTRK1 is a receptor for nerve growth factor (NGF). This protein induces outgrowth of axons and dendrites and promotes the ... missense mutations on autophosphorylation of the receptor tyrosine kinase for nerve growth factor". Human Molecular Genetics. ... CIPA is caused by a genetic mutation which prevents the formation of nerve cells which are responsible for transmitting signals ... In addition, patients typically lack unmyelinated and small myelinated nerve fibers in the dorsal root ganglion. Both are ...
*  Anicequol
TF-0356 which has nerve growth factor-like neurotrophic activity. It was under investigation by Taisho Pharmaceutical in Japan ... discovery of low molecular weight compounds that stimulate neurite outgrowth and substitute for nerve growth factor". J. ...
*  Fellutamide
... A and B, a tripeptide derivative from Penicillium fellutanum, stimulate nerve growth factor synthesis in vitro. ... May 2008). "Proteasome inhibition by fellutamide B induces nerve growth factor synthesis". Chem Biol. 15 (5): 501-512. doi: ... "Stimulation of nerve growth factor synthesis and secretion by fellutamide A in vitro". Biosci Biotechnol Biochem. 57 (2): 195- ...
*  Apomorphine
"Effects of nerve growth factor (NGF), fluoxetine, and amitriptyline on gene expression profiles in rat brain". Neuropeptides. ... "Epigenetic down regulation of nerve growth factor during alcohol withdrawal". Addiction Biology. 18 (3): 508-510. doi:10.1111/j ... Apomorphine is a powerful upregulator of certain neural growth factors, in particular NGF and BDNF, epigenetic downregulation ... It is classically thought that an excess of dopamine stimulation is a factor in schizophrenia, but it appears this relationship ...
*  PTPRR
The rat counterpart of this gene was reported to be regulated by the nerve growth factor, which suggested the function of this ... Sharma E, Lombroso PJ (1995). "A neuronal protein tyrosine phosphatase induced by nerve growth factor". J. Biol. Chem. 270 (1 ... PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, ... gene in neuronal growth and differentiation. PTPRR has been shown to interact with MAPK7. GRCh38: Ensembl release 89: ...
*  Dependence receptor
June 2013). "Dependence receptor UNC5D mediates nerve growth factor depletion-induced neuroblastoma regression". The Journal of ... Neogenin p75NTR Ptch1 CDON PLXND1 RET TrkA TrkC EphA4 c-Met Insulin Receptor IR Insulin-like growth factor 1 receptor ALK ( ... A trophic ligand is a molecule whose protein binding stimulates cell growth, differentiation, and/or survival. Cells depend for ... Apoptosis Axon guidance Metastasis suppressor Programmed cell death Signal transduction Trophic factor Tumor suppressor genes. ...
*  SERPINI1
2002). "Neuroserpin regulates neurite outgrowth in nerve growth factor-treated PC12 cells". J. Neurochem. 82 (6): 1406-15. doi: ... "Neuroserpin regulates neurite outgrowth in nerve growth factor-treated PC12 cells". J. Neurochem. England. 82 (6): 1406-15. doi ...
*  NGFRAP1
"Entrez Gene: NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1". Kimura MT, Irie S, Shoji-Hoshino S, Mukai J ... NGFRAP1 has been shown to interact with YWHAE and Low affinity nerve growth factor receptor. GRCh38: Ensembl release 89: ... identification of regions that mediate nerve growth factor-induced apoptosis". J. Biol. Chem. 277 (16): 13973-82. doi:10.1074/ ... Tong X, Xie D, Roth W, Reed J, Koeffler HP (2003). "NADE (p75NTR-associated cell death executor) suppresses cellular growth in ...
*  Communist Party of China
With other social factors, the conflicts culminated in the 1989 Tiananmen Square protests. The protests having been crushed, ... The insistence on focusing on economic growth led to a wide range of serious social problems. To address these, Hu introduced ... "nerve centre", in charge of day-to-day administrative work, including communications, protocol, and setting agendas for ... While asserting the political power of the Party, the change in policy generated significant economic growth. The new ideology ...
*  Kalirin
"Critical role for Kalirin in nerve growth factor signaling through TrkA". Mol. Cell. Biol. 25 (12): 5106-18. doi:10.1128/MCB. ... Is also known to play an important role in nerve growth and axonal development. Kalirin is a member of the Dbl family of ... with a rac1 guanine nucleotide exchange factor domain". Hum. Mol. Genet. 6 (9): 1519-25. doi:10.1093/hmg/6.9.1519. PMID 9285789 ... proteins and is a Rho guanine nucleotide exchange factor. It is named after the multiple-handed Hindu goddess Kali for its ...