... the interruption or elimination of sensory nerve impulses by injuring or damaging sensory nerve fibers) because injury to the ... Retrograde transneuronal degeneration is degeneration caused by loss of trophic support from the target. It occurs in ... It is often termed "dying forward," and is also referred to as trans-synaptic degeneration. Anterograde degeneration can occur ... There are varying degrees of degeneration. In mild degeneration the cytoplasmic areas shrinks and increases in density and ...
... is a peripheral neuropathy involving the degeneration of myelin sheathing and/or nerves that innervate the head, body, and ... Normal impulses in peripheral nerves of the legs travel at 40-45 m/s, and those in peripheral nerves of the arms at 50-65 m/s. ... Nerve conduction studies are performed as follows: Two electrodes are attached to the subject's skin over the nerve being ... Carpal tunnel syndrome (CTS) is a form of nerve compression syndrome caused by the compression of the median nerve at the wrist ...
Nerve injury) Connective tissue in the peripheral nervous system Neuroregeneration Wallerian degeneration "Peripheral Nerve ... Classification of nerve injury was described by Seddon in 1943 and by Sunderland in 1951. The lowest degree of nerve injury in ... There is no nerve conduction distal to the site of injury (3 to 4 days after lesion). EMG and NCV findings show no distal ... There is no nerve conduction distal to the site of injury (3 to 4 days after injury). EMG shows fibrillation potentials (FP), ...
... observation of spinal nerve root degeneration". Anesthesia and Analgesia. 75 (6): 895-9. doi:10.1213/00000539-199212000-00006. ... cervical nerve block, occipital nerve block. mandibular nerve block or maxillary nerve block for dental anesthesia, ophthalmic ... anesthesia via infraorbital nerve block, ulnar nerve block, paravertebral block, intercostal nerve block, sciatic nerve block, ... It is also used for obstetric anesthesia including pudendal nerve block and paracervical block. Chloroprocaine is also ...
Hinton, D. R., Sadun, A. A., Blanks, J. C., & Miller, C. A. (1986). Optic-nerve degeneration in Alzheimer's disease. New ... Hinton, David R.; Sadun, Alfredo A.; Blanks, Janet C.; Miller, Carol A. (August 21, 1986). "Optic-Nerve Degeneration in ... Carelli, Valerio; Ross-Cisneros, Fred N.; Sadun, Alfredo A. (May 1, 2002). "Optic nerve degeneration and mitochondrial ... Sadun has focused his research on diseases of the optic nerve, diseases of mitochondrial impairment, optic nerve regeneration, ...
"Macular Degeneration types and risk factors". Archived from the original on 2010-01-10. Retrieved 2010-01-26. Wedl C. Grundzüge ... Optical coherence tomography scans of the orbits or head, calcification at the head of the optic nerve without change in size ... "Age-Related Macular Degeneration". National Eye Institute. March 2008. Archived from the original on 2008-05-12. Retrieved 2008 ... Hard drusen' may coalesce into 'soft drusen' which is a manifestation of macular degeneration. Around 1850, three authors, Carl ...
In tellurium-induced demylenation with no axon degeneration, nerve crush with axon degeneration, and nerve transection with ... Wallerian degeneration is a process that occurs before nerve regeneration and can be described as a cleaning or clearing ... Electrically, the nerve shows rapid and complete degeneration, with loss of voluntary motor units. Regeneration of the motor ... on nerve autografts and tissue-engineered nerve grafts". Muscle & Nerve. 26 (1): 87-93. doi:10.1002/mus.10165. PMID 12115953. ...
LNGFR also activates a caspase-dependent signaling pathway that promotes developmental axon pruning, and axon degeneration in ... "The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's ... Nerve growth factor (NGF) is a neurotrophin that promotes neuronal growth, and, in the absence of NGF, neurons die. Neuronal ... Nerve+Growth+Factor+Receptor,+Low-Affinity at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Articles ...
"Capsaicin Induces Degeneration of Cutaneous Autonomic Nerve Fibers". Annals of Neurology. 68 (6): 888-898. doi:10.1002/ana. ... and proximal thigh prepared for standard analysis of intraepidermal nerve fiber density (IENFD). Nerve fibers innervating sweat ... As the test lacks an axon-reflex response, it has a limited ability to assess nerve fiber function. SSR refers to the change in ... NPhys Trial". Muscle & Nerve. 42 (2): 157-164. doi:10.1002/mus.21661. PMC 2956592. PMID 20658599. Vitale, G.I.; Quatrale, R.P ...
Capsaicin causes reversible degeneration of epidermal nerve fibers. Notably the capsaicin used for the relief of neuropathic ... Cranial nerves Nerve Neuralgia Neuritis Neuropathy DiBonaventura, Marco D.; Sadosky, Alesia; Concialdi, Kristen; Hopps, Markay ... Galen also suggested nerve tissue as the transferring route of pain to the brain through the invisible psychic pneuma. The idea ... Neuropathic pain is common in cancer as a direct result of cancer on peripheral nerves (e.g., compression by a tumor), or as a ...
Iwashita, H.; Inoue, N.; Kuroiwa, Y. (1969). "Familial optic and acoustic nerve degeneration with distal amyotrophy". Lancet. ...
Axonal degeneration was correlated with degree of endoneurial edema. In a few case reports (surgical resection of nerve, ... While nerve decompression may be used on any nerve, nerve resection should only be used on purely sensory nerves when the loss ... The superior cluneal nerves, middle cluneal nerves, posterior femoral cutaneous nerve, lateral femoral cutaneous nerve are all ... Outcomes for nerve resection is similar to nerve decompression. One disadvantage of nerve resections is that traumatic injury ...
Patients with cerebellar degeneration experience a progressive loss of nerve cells (Purkinje cells) throughout the cerebellum. ... "Cerebellar degeneration". Clinical Advisor. 2016-12-20. Retrieved 2018-10-09. "Cerebellar degeneration". Genetic and Rare ... There are two types of cerebellar degeneration; paraneoplastic cerebellar degeneration, and alcoholic or nutritional cerebellar ... Nutritional and alcoholic cerebellar degeneration, being more prevalent than paraneoplastic cerebellar degeneration, affects ...
Oppenheim, Janet (1991). "Nervous Degeneration". "Shattered Nerves": Doctors, patients, and depression in Victorian England. ... The forces of degeneration opposed those of evolution, and those afflicted with degeneration were thought to represent a return ... Degeneration theory achieved a detailed articulation in Bénédict Morel's Treatise on Degeneration of the Human Species (1857), ... He rarely made a specific references to the theory of degeneration, and his attitude towards degeneration theory was not ...
He examined the degeneration of nerve endings in Eimer's organ in moles following sectioning of the trigeminal nerve. His group ... His major experimental work was on nerve degeneration and regeneration. In 1940 he published Problems of nervous anatomy which ... In 1925 he and a colleague examined the regeneration of sensation of a colleague who had lacerated a nerve at his wrist. Blair ... While in Naples he met the Hungarian histologist István Apáthy who introduced him to the complexity of nerves and the problems ...
Degeneration of nerve tissue in the spinal cord causes the ataxia; particularly affected are the sensory neurons essential for ... Degeneration of nerve tissue in the spinal cord causes ataxia. The sensory neurons essential for directing muscle movement of ... The disease primarily affects the spinal cord and peripheral nerves. The spinal cord becomes thinner and nerve cells lose some ... In peripheral nerves, a loss of large myelinated sensory fibers occurs. Structures in the brain are also affected by FRDA, ...
Iron overload primarily affects nerve cells in the substantia nigra and basal ganglia. Here, a slowly progressive degeneration ... Testicular atrophy, erectile dysfunction and degeneration of penile tissue degeneration (shrinking of the shaft) in male ...
Abnormalities were found in muscle and sural nerves. It was concluded by Mousa-Al et al. that the disease is different from a ... Symptoms include a combination of spinocerebellar degeneration and corneal dystrophy. Mental retardation and slowly progressive ... "OMIM Entry - 271310 - SPINOCEREBELLAR DEGENERATION AND CORNEAL DYSTROPHY". OMIM. 21 October 2014. Retrieved 18 May 2016. Der ... "Familial spinocerebellar degeneration with corneal dystrophy". Am. J. Med. Genet. 20 (2): 325-39. doi:10.1002/ajmg.1320200216. ...
The result is muscle degeneration and demyelination of peripheral nerves. The mouse model of laminin-α2-deficient congenital ... MPTP-induced nigrostriatal degeneration, and oxidopamine-induced neuronal injury. Omigapil also prevents the death of ...
There may also be demyelination (loss of the nerve's myelin sheath) and degeneration of the nerve in the affected area but it ... Facial nerve decompression is a type of nerve decompression surgery where abnormal compression on the facial nerve is relieved ... Pressure and compression of any cause on a peripheral nerve can cause nerve impulse block. That is, the nerve is no longer able ... The facial nerve is a mixed nerve (i.e. containing both sensory and motor nerve fibres) and therefore compression can create ...
Axonal degeneration and regeneration are common processes in many nerve disorders. As a consequence of myelin remodeling, the ... Changes in the geometry of the nerve due to loss of axons within the peripheral nerve likely cause this shift in rheobase. A ... As a result, sensory nerves have a longer strength-duration time constant and a lower rheobase than motor nerves. Many studies ... Krarup, C., & Mihai, M. (2009). "Nerve conduction and excitability studies in peripheral nerve disorders". Current Opinion in ...
... and degeneration of the nerve that stimulates the diaphragm (phrenic nerve). This can prolong the time it takes to wean a ... and nerve and muscle degeneration are difficult to distinguish from each other in this condition. Terms used for the condition ... Nerve biopsy would show axonal neuropathy, but it is no longer indicated. A muscle biopsy of critical illness myopathy would ... The peroneal nerve test is a validated, high-sensitivity, minimally invasive, non-volitional and quick diagnostic test which ...
"Very early activation of m-calpain in peripheral nerve during Wallerian degeneration". J. Neurol. Sci. 196 (1-2): 9-20. doi: ... as well as secondary degeneration resulting from acute cellular stress following myocardial ischemia, cerebral (neuronal) ...
"Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging". Nature Communications. 7 (1 ...
He died on September 11, 2005, in Warsaw, Poland of progressive nerve degeneration. 1948 - Five Golds Medals, International ...
They may cause axon degeneration, or they may simply cause axons to malfunction. The myelin sheath allows nerve cells to ... Sensory and proprioceptive nerves in the hands and feet are often damaged, while unmyelinated pain nerves are left intact. ... CMT can be diagnosed through three different forms of tests: measurement of the speed of nerve impulses (nerve conduction ... Nerve signals are conducted by an axon with a myelin sheath wrapped around it. Most mutations in CMT affect the myelin sheath, ...
This degeneration also occurs in normal aging but is a much slower process. The most common symptoms include: tremors, slowness ... Movement is normally controlled by dopamine; a chemical that carries signals between the nerves in the brain. When cells that ... Too much iron in the body can create free radicals which could influence the degeneration of the blood-brain barrier. One other ... Many factors such as genetics and neural degeneration have a part in causing memory disorders. In order to diagnose Alzheimer's ...
He was the first to describe the degeneration of severed nerve fibers, now known as Wallerian degeneration. The son of William ... and he invented the degeneration method of studying the paths of nerve impulses. He practically rediscovered the power which ... The function of the ganglion on the posterior root of each spinal nerve is published in the 'Comptes Rendus' (xxxv. 524). 'The ... The Wallerian degeneration is described in the 'Comptes Rendus,' 1 Dec. 1851. The demonstration of the cilio-spinal centre was ...
Pressure on the nerves as they exit the spinal cord (radiculopathy) causes pain in the area where the nerves originated (leg ... Degeneration happens more frequently at these levels due to increased motion and stress. The thoracic spine is more immobile, ... Each technique varies depending on the level of the spine and the location of the compressed spinal cord/nerves. After the ... Adjacent segment disease - degeneration of vertebrae above/below the fused segments due altered biomechanical stresses or ...
Kujawa SG, Liberman MC (November 2009). "Adding insult to injury: cochlear nerve degeneration after "temporary" noise-induced ... Kujawa SG, Liberman MC (November 2009). "Adding insult to injury: cochlear nerve degeneration after "temporary" noise-induced ... Kujawa SG, Liberman MC (December 2015). "Synaptopathy in the noise-exposed and aging cochlea: Primary neural degeneration in ... Kujawa has examined the vulnerability of the synapses that connect hair cells in the cochlea to auditory nerve fibers. Their ...
... and retinal degeneration. Occasional findings include optic nerve atrophy. This condition has many complications associated ... It is a type of progressive vitreotapetoretinal degeneration. This condition is more common among Marrano Jews living in ... retinal degeneration, and nightblindness. If they remain un-treated, they can end up in severe vision impairment. Goldmann- ... "Clinical features of Goldmann-Favre vitreoretinal degeneration". Archivos de la Sociedad Española de Oftalmología (English ...
He also won the Ellis Prize in Physiology for his essay, "The chemistry of nerve degeneration." In 1913, he joined the staff of ... "The chemistry of nerve degeneration". {{cite journal}}: Cite journal requires ,journal= (help) Hayward, J. A. (8 September 1923 ...
... is an active process of degeneration that results when a nerve fiber is cut or crushed and the part of ... The only known effect is that the Wallerian degeneration is delayed by up to three weeks on average after injury of a nerve. At ... Turner JE, Glaze KA (March 1977). "The early stages of Wallerian degeneration in the severed optic nerve of the newt (Triturus ... Stoll G, Müller HW (April 1999). "Nerve injury, axonal degeneration and neural regeneration: basic insights". Brain Pathology. ...
"Degeneration of Axenfeld nerve loop: a clinicopathologic case report". Canadian Journal of Ophthalmology. 50 (2): e33-34. doi: ... "Axenfeld's nerve loop": A posterior ciliary nerve loop that is noticeable in the sclera. "Axenfeld syndrome": A syndrome ...