May 2010). "Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury". Stem Cell Research. 4 (3): 214-22. doi: ...
"Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice". FASEB Journal. 22 (10): 3549-60. doi: ... HDIs are also being studied as protection of heart muscle in acute myocardial infarction. Miller TA, Witter DJ, Belvedere S ( ...
Alam, M.R.; D. Baetz; M. Ovize (2015). "Cyclophilin D and myocardial ischemia-reperfusion injury: a fresh perspective". J Mol ... Reperfusion injury Reperfusion therapy Eltzschig, H.K. & T. Eckle (2011). "Ischemia and reperfusion-from mechanism to ... Ischemia-reperfusion (IR) tissue injury is the resultant pathology from a combination of factors, including tissue hypoxia, ... The ischemia-reperfusion injury associated with surgical tourniquets is typically not clinically apparent when used for less ...
"Effect of trapidil in myocardial ischemia-reperfusion injury in rabbit". Indian Journal of Pharmacology. 46 (2): 207-210. doi: ...
"Nerve growth factor reduces myocardial ischemia/reperfusion injury in rat hearts". Journal of Basic and Clinical Physiology and ... and traumatic brain injury. Lazarovici also contributed to the characterization of NGF angiogenic properties and ... "Ischemia"-Stressed PC12 Pheochromocytoma Cells". Brain Sciences. 8 (2): 32. doi:10.3390/brainsci8020032. PMC 5836051. PMID ... pan-hematopoietic subpopulation derived from human umbilical cord blood in a traumatic brain injury model". Cytotherapy. 20 (2 ...
Neuhof C, Neuhof H (2014). "Calpain system and its involvement in myocardial ischemia and reperfusion injury". World J Cardiol ... ischemia, traumatic brain injury and spinal cord injury. Excessive amounts of calpain can be activated due to Ca2+ influx after ... as well as secondary degeneration resulting from acute cellular stress following myocardial ischemia, cerebral (neuronal) ... or some types of traumatic brain injury such as diffuse axonal injury. Increase in concentration of calcium in the cell results ...
"Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice". Arteriosclerosis, Thrombosis, and ...
A deletion of the C-terminal 19 amino acids was found during myocardial ischemia-reperfusion injury in Langendorff perfused rat ... "Troponin I degradation and covalent complex formation accompanies myocardial ischemia/reperfusion injury". Circulation Research ... It was also seen in myocardial stunning in coronary bypass patients. Over-expression of the C-terminal truncated cardiac TnI ( ... Ni CY (2002). "Cardiac troponin I: a biomarker for detection and risk stratification of minor myocardial damage". Clinical ...
Moens, A.L.; Claeys, M.J.; Timmermans, J.P.; Vrints, C.J. (April 2005). "Myocardial ischemia/reperfusion-injury, a clinical ... However, it is more commonly associated with reperfusion after myocardial injury. AIVR is generally considered to be a benign ... Norris, RM; Mercer, CJ (Mar-Apr 1974). "Significance of idioventricular rhythms in acute myocardial infarction". Progress in ... Accelerated idioventricular rhythm is the most common reperfusion arrhythmia in humans. However, ventricular tachycardia and ...
Hydrogen Sulfide Donor Protects Against Acute Myocardial Ischemia-Reperfusion Injury". Circulation. 114 (suppl_18): II_172. doi ... Reperfusion injury, sometimes called ischemia-reperfusion injury (IRI) or reoxygenation injury, is the tissue damage caused ... Repeated bouts of ischemia and reperfusion injury also are thought to be a factor leading to the formation and failure to heal ... For example brain ischemia/reperfusion injury is mediated via complex I redox-dependent inactivation. It was found that lack of ...
"AGGF1 protects from myocardial ischemia/reperfusion injury by regulating myocardial apoptosis and angiogenesis". Apoptosis. 19 ... Additionally, AGGF1 has been shown to protect against inflammation and ischemic injuries. During embryongenesis, AGGF1 is ... for Blocking Neointimal Formation After Vascular Injury". Journal of the American Heart Association. 6 (6): e005889. doi: ... has also been implicated in treatment after vascular smooth muscle cell damage due to coronary artery disease and myocardial ...
November 2013). "Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury". Journal of ... which play a role in myocardial reperfusion injury. This was a result of the relation between Nox2 and signaling necessary for ... the protein can be a potential target for drug medication due to its negative effect on myocardial reperfusion. Recent evidence ... It has also been shown to play a part in determining the size of a myocardial infarction due to its connection to ROS, ...
"Protective role of deoxyschizandrin and schisantherin a against myocardial ischemia-reperfusion injury in rats". PLOS ONE. 8 (4 ...
"Cardioprotection with forsythoside B in rat myocardial ischemia-reperfusion injury: relation to inflammation response". ... January 2019). "Protective effect of forsythoside B against lipopolysaccharide-induced acute lung injury by attenuating the ...
In addition, palmatine might have the antiarrhythmic effect, and provideprotection from myocardial ischemia-reperfusion injury ...
... protects the isolated rat heart from the myocardial injuries produced by ischemia and reperfusion. Planta Med, 1993 ... Cyclobuxine was in this way able to suppress the damage (myocardial injury) produced by ischemia. As indicated above, research ... cyclobuxine was also found to have a protective effect on myocardial cells against ischemia and reperfusion (in an isolated rat ... proven to inhibit the release of ATP metabolites and prevent the release of creatine phosphokinase that is induced by ischemia ...
A major topic of research is the impact of hydrogen sulfide on reducing myocardial ischemia-reperfusion injury. Reperfusion ... "Roles of the nitric oxide signaling pathway in cardiac ischemic preconditioning against myocardial ischemia-reperfusion injury ... Reperfusion triggers an inflammatory response and often results in oxidative damage. H2S decreases injury through many ... The mitochondria has been known to protect the heart from ischemic-reperfusion injury through the opening of the ATP-sensitive ...
"Mitochondrial connexin43 as a new player in the pathophysiology of myocardial ischaemia-reperfusion injury". Cardiovascular ... In still other cells connexons have been shown to occur in mitochondrial membranes and appear to play a role in heart ischaemia ... In the central nervous system (CNS), connexons play a major role in conditions such as epilepsy, ischemia, inflammation, and ... which plays a part in ventricular remolding and healing of wounds after a myocardial infarction, are present in structural ...
... binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury ...
"Beta3-Adrenoreceptor Stimulation Ameliorates Myocardial Ischemia-Reperfusion Injury Via Endothelial Nitric Oxide Synthase and ...
In a mouse model of infarction the A3 selective agonist CP-532,903 protected against myocardial ischemia and reperfusion injury ... protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP-sensitive potassium channel". The Journal of ... reduces ischemia/reperfusion injury in mice by activating the A3 adenosine receptor". The Journal of Pharmacology and ... Dougherty C, Barucha J, Schofield PR, Jacobson KA, Liang BT (December 1998). "Cardiac myocytes rendered ischemia resistant by ...
Prevents Spontaneous Ventricular Arrhythmias and Reduces Infarct Size During Myocardial Ischemia/Reperfusion Injury in Open- ... Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide ...
Her research primarily focuses on the molecular basis of myocardial ischemia/reperfusion injury and on developing ways to ... with particular attention to the molecular basis of myocardial ischemia/reperfusion injury and in developing ways to mitigate ... Her subsequent work has explored the role of proteases and mitochondrial dysfunction in ischemia/reperfusion injury, and most ... "Enhancing Macroautophagy Protects against Ischemia/Reperfusion Injury in Cardiac Myocytes". "Gottlieb Lab". Delbridge, Lea M. D ...
"Sulodexide attenuates myocardial ischemia/reperfusion injury and the deposition of C-reactive protein in areas of infarction ... Research has also demonstrated the beneficial effects of sulodexide in animal models of reperfusion injury and the treatment of ...
Zheng, Pengfei (2017-02-20). "Plin5 alleviates myocardial ischaemia/reperfusion injury by reducing oxidative stress through ... deficiency in PLIN5 initiates excessive phosforilation of PI3K/Akt which contributes to ischemia-reperfusion injury aggravation ... Wang, Hong (2013). "Cardiomyocyte-specific perilipin 5 overexpression leads to myocardial steatosis and modest cardiac ...
In solid-organ transplantation, ischemia-reperfusion injury can occur when blood returns to tissue for the first time in the ... Necroptosis has been implicated in the pathology of many types of acute tissue damage, including myocardial infarction, stroke ... ischemia-reperfusion injury. In addition, necroptosis is noted to contribute to atherosclerosis, pancreatitis, inflammatory ... and myocardial infarction. The signaling pathway responsible for carrying out necroptosis is generally understood. TNFα leads ...
... pressure overload and prevented myocardial ischemia/reperfusion injury in a mouse or pig model of ischemia/reperfusion. Muscle- ... "Therapeutic impact of follistatin-like 1 on myocardial ischemic injury in preclinical models". Circulation. 126 (14): 1728-38. ... FSTL1 has been shown to have a pronounced ability as a possible therapeutic to stimulate regeneration following myocardial ... Treating experimental animals (mouse and pig) with FSTL1 after myocardial infarction progressively restored heart function, at ...
Platelets protect against myocardial dysfunction and injury induced by ischemia and reperfusion in isolated rat hearts. ... Mehta's thesis topic was "studies on experimental myocardial reperfusion" which he completed under the direction of Prof. Tom ... Critical role of AT1 receptor expression after ischemia-reperfusion in isolated rat hearts: Beneficial effect of antisense ... its polymorphic variants and its role in atherogenesis and myocardial ischemia has led to new therapeutic targets now being ...
... mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce ... Midiv-1 has been demonstrated to attenuate the effects of ischemia reperfusion injury after cardiac arrest. The treatment ... FK506 was shown to also preserve mitochondrial morphology after reperfusion injury. GRCh38: Ensembl release 89: ENSG00000087470 ...
... inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury". ... In a number of severe, acute diseases (such as stroke, neurotrauma, circulatory shock, and acute myocardial infarction), PARP ... Virág L, Salzman AL, Szabó C (October 1998). "Poly(ADP-ribose) synthetase activation mediates mitochondrial injury during ...