Tuberculosis is a disease caused by the bacterium Mycobacterium tuberculosis. The nature of the host-pathogen interaction ... observed in a subset of individuals with a genetic defect that results in increased susceptibility to Mycobacterial infection.[ ... Tuberculosis. Recent Genome-wide association studies (GWAS) have identified three genetic risk loci, including at positions ... "Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians". Nature Communications. 10 (1 ...
Sendai virus is used as a backbone for vaccine development against Mycobacterium tuberculosis that causes tuberculosis, against ... If a mouse survives a SeV infection, it develops a lifelong immunity to subsequent viral infections. There are SeV-resistant ... February 2000). "Green fluorescent protein gene insertion of Sendai Virus infection in nude mice: possibility as an infection ... "Immunogenicity and therapeutic effects of Ag85A/B chimeric DNA vaccine in mice infected with Mycobacterium tuberculosis". FEMS ...
... as well as for the bacterium Mycobacterium tuberculosis, the major causative agent of tuberculosis. In this latter case, ICL ... For instance, increased gene expression of icl1 has been seen in the fungus Leptosphaeria maculans upon infection of canola. ... "Potential inhibitors for isocitrate lyase of Mycobacterium tuberculosis and non-M. tuberculosis: a summary". BioMed Research ... "Selection of genes of Mycobacterium tuberculosis upregulated during residence in lungs of infected mice". Tuberculosis. 88 (3 ...
... and is about twice as potent as ofloxacin against Mycobacterium tuberculosis and other mycobacteria, including Mycobacterium ... Levofloxacin is used to treat infections including: respiratory tract infections, cellulitis, urinary tract infections, ... urinary tract infections, and abdominal infections. As of 2007 the Infectious Disease Society of America (IDSA) and the ... uncomplicated skin infections, complicated urinary tract infections, and acute pyelonephritis. Levofloxacin is marketed by ...
... disseminated or extrapulmonary Mycobacterium, other species, disseminated or extrapulmonary Mycobacterium tuberculosis, any ... facilitating further systemic infection and inflammation. In physiologically typical individuals, the infection will generally ... Mycobacterium tuberculosis, any site (pulmonary) Pneumonia (recurrent) Additional conditions are included for children younger ... of brain Mycobacterium avium complex or Mycobacterium kansasii, ... Toxoplasma, like most parasites, carries out its infection in ...
... is a specific type of bacterial meningitis caused by the Mycobacterium tuberculosis infection of the meninges-the system of ... Mycobacterium tuberculosis of the meninges is the cardinal feature and the inflammation is concentrated towards the base of the ... The two most common commercially available tests are the amplified mycobacterium tuberculosis direct test (MTD, Gen-Probe) and ... "A systematic review of rapid diagnostic tests for the detection of tuberculosis infection". Health Technol Assess. 11 (3): 1- ...
He also contributed important initial studies on the two co-evolved human pathogens, namely, Mycobacterium tuberculosis and ... "Niyaz Ahmed - Editorial Board - Infection, Genetics and Evolution - Journal - Elsevier". "Helicobacter". doi:10.1111/(ISSN)1523 ... Editor in Chief Infection Genetics and Evolution - Receiving Editor Helicobacter - Editorial Board Member Ahmed has been ... Implications for Global Infection Control Priorities". The Journal of Infectious Diseases. 224 (Supplement_7): S876-S882. doi: ...
... by Mycobacterium tuberculosis during infection of host cells, and by SARS-CoV-2 ORF3a's MLKL-like action at the plama membrane ... such as Mycobacterium tuberculosis). This has placed immunity and infection on the repertoire of autophagy's sphere of ... "Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages". Cell. 119 (6 ... "Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages". Cell. 119 (6 ...
Diagnosis of urogenital C. trachomatis infections Detection of Mycobacterium tuberculosis Detection of HIV RNA or DNA Detection ... Diagnosis of Gonococcal and other Neisserial infections: Amplification of specific N. gonorrhoea DNA or RNA sequences for ... Ridderhof, John C (2009). Tuberculosis. Elsevier. pp. 738-745. Gillespie, Susan L. (2013). Clinical Immunology (Fourth Edition ...
... to the modern era as carbon monoxide currently has preclinical evidence of treating Mycobacterium tuberculosis infection ... Tuberculosis was a primary disease physicians had attempted to treat with factitious airs, particularly since James Watt's ... September 2016). "The emerging role of gasotransmitters in the pathogenesis of tuberculosis". Nitric Oxide. 59: 28-41. doi: ... John Carmichael had reported successfully treating a patient suffering from tuberculosis using hydrocarbonate. This application ...
Infections HIV/AIDS Tuberculosis Mycobacterium avium-intracellulare infection Infectious mononucleosis Fungal infections ( ...
... disease is believed to be spread through respiratory droplets in close quarters like its relative Mycobacterium tuberculosis, ... Early infection is characterized by a well demarcated, usually pale, skin lesion which has lost its hair, and there may be many ... In this form of leprosy Mycobacterium leprae are found in lesion in large numbers. This is the most unfavorable clinical ... and signs of infection may not appear for years. Family members of those with the disease, and especially children, are most at ...
Guidelines for Using the QuantiFERON-TB Gold Test for Detecting Mycobacterium tuberculosis Infection, United States British ... Collins, LF; Geadas, C; Ellner, JJ (2016), "Diagnosis of latent tuberculosis infection: too soon to pull the plug on the ... latent tuberculosis infection diagnosis and treatment is considered for any BCG-vaccinated person whose skin test is 10 mm or ... and is useful for initial and serial testing of persons with an increased risk of latent or active tuberculosis infection. ...
This may be associated with infections due to bacteria like Mycobacterium tuberculosis, the cause of tuberculosis, and fungi ... 2008). "Orbital tuberculosis: A review of the literature". Orbit. Amsterdam, Netherlands. 27 (4): 267-77. doi:10.1080/ ... Tuberculous cervical lymphadenitis Garg, RK; Somvanshi, DS (2011). "Spinal tuberculosis: A review". The Journal of Spinal Cord ... Cold abscess refers to an abscess that lacks the intense inflammation usually associated with infection. ...
Macrophages are polarized toward the M1 profile during the early phase of Mycobacterium tuberculosis infection, as well as ... "Differential pattern of cytokine expression by macrophages infected in vitro with different Mycobacterium tuberculosis ... A number of studies have shown that bacterial infection induces polarization of macrophages toward the M1 phenotype, resulting ... Kreider T, Anthony RM, Urban JF, Gause WC (August 2007). "Alternatively activated macrophages in helminth infections". Current ...
... caused by Mycobacterium leprae) and Mycobacterium avium-intracellulare infection (caused by Mycobacterium avium complex) in ... Mycobacterium bovis causes tuberculosis in cattle. Since tuberculosis can be spread to humans, milk is pasteurized to kill any ... Mycobacterium tuberculosis that causes tuberculosis (TB) in humans is an airborne bacterium that typically infects the human ... caused by Mycobacterium tuberculosis) and other diseases caused by atypical mycobacteria, such as leprosy ( ...
However, lipoxins also have harmful effects in these models: aerosol infection with Mycobacterium tuberculosis in transgenic ... Lipoxins have protective effects in animal models of infection-based inflammation: a) LXA4 and a LXA4 analog decreased systemic ... Tampa Liposuction Basil MC, Levy BD (2016). "Specialized pro-resolving mediators: endogenous regulators of infection and ...
Mycobacterium tuberculosis, the main cause of tuberculosis in humans, and Mycobacterium bovis, the main cause of tuberculosis ... It is caused by the bacterium Mycobacterium avium subspecies paratuberculosis. Infections normally affect ruminants (mammals ... by the lack of Mycobacterium tuberculosis, rather than the presence of any specific infectious agent, leaving ambiguous the ... Late in the infection, antibody production by the animal occurs to M. paratuberculosis in serum of animals, and is an indicator ...
The impact of co-infections by micro-organisms such as Mycobacterium tuberculosis can be important in disease progression, ... Individuals with a broad expansion of the V-beta chain of the T cell receptor of CD8+ T cells during primo-infection appear to ... Co-infection with DNA viruses such as HTLV-1, herpes simplex virus-2, varicella zoster virus and cytomegalovirus may enhance ... Following infection with HIV-1, the rate of clinical disease progression varies between individuals. Factors such as host ...
... or after infection of monocytes herpes virus, Mycobacterium tuberculosis and Candida albicans (Figure 2). The prevailing ... Ahmad A, Ahmad R, Iannello A, Toma E, Morisset R, Sindhu ST (July 2005). "IL-15 and HIV infection: lessons for immunotherapy ... In humans with history of acute infectious mononucleosis (the syndrome associated with primary Epstein-Barr virus infection), ... following infection by virus(es). This cytokine induces the proliferation of natural killer cells, i.e. cells of the innate ...
... notably Mycobacterium tuberculosis) can trick the body into getting locked in the wrong mode of attack, using an antibody- ... Viral infections increase cortisol levels through activation of the HPA axis by cytokines. Intense (high VO2 max) or prolonged ... But in a severe infection or in a situation where the immune system is overly sensitized to an antigen (such as in allergic ... The activation of the stress system (and resulting increase in cortisol and Th2 shift) seen during an infection is believed to ...
Mycobacterium bovis, M. tuberculosis and M. microti) have been isolated from cats and associated with infection with the ... This infection in humans is sometimes mistaken for tuberculosis. Onchocercosis has been associated with pet cats in a few cases ... When the infection has expanded to severe symptoms, it can be lethal. The signs of cowpox infection in cats can be seen as, ... If jaundice is a symptom the infection becomes more severe and rapidly progresses. Different strains of the tuberculosis ...
... while presenting increased resistance to infection with tuberculosis (Mycobacterium bovis) compared to their forebears. The ...
Comparative and Functional Genomics of Mycobacterium tuberculosis 2004 Stanley Falkow, Thoughts on Persistent Bacterial ... My Favourite Infection 1990 Paul M. Nurse (now Sir Paul), On Fission 1992 John R. Guest, Oxygen-regulated Gene Expression in E ... Infections 2006 Sir John Skehel, Invasion by Influenza Viruses 2008 Alan B. Rickinson, Studies with an Oncogenic Virus: How to ...
This includes fungal infections, mycobacterial infections such as tuberculosis or mycobacterium avium intracellulare, ...
Xu H, Hazra S, Blanchard JS (June 2012). "NXL104 irreversibly inhibits the β-lactamase from Mycobacterium tuberculosis". ... The most important use of beta-lactamase inhibitors is in the treatment of infections known or believed to be caused by gram- ... is a slow substrate that inhibits the β-lactamase from Mycobacterium tuberculosis". Biochemistry. 53 (22): 3671-8. doi:10.1021/ ... "Can inhibitor-resistant substitutions in the Mycobacterium tuberculosis β-Lactamase BlaC lead to clavulanate resistance?: a ...
2015). "Eighteenth-century genomes show that mixed infections were common at time of peak tuberculosis in Europe". Nature ... 2014). "Culture-independent detection and characterisation of Mycobacterium tuberculosis and M. africanum in sputum samples ... recovering 200-year-old Mycobacterium tuberculosis genomes from human remains and a medieval Brucella genome sequence. With ... Subsequently, in an opinion piece in the journal New Microbes and New Infections and an invited talk for Bergey's International ...
Hepatitis B and Hepatitis C Histoplasmosis Herpes virus infections Mycobacterium avium complex disease Tuberculosis Established ... Through innovative studies of the treatment of HIV-1 infection and its complications, ACTG research focuses on: New therapies ... playing a major role in setting standards of care for HIV infection and opportunistic diseases related to HIV and AIDS in the ... for many opportunistic infections and malignancies. In 1986, the original AIDS Treatment and Evaluation Units were established ...
... on Mycobacterium tuberculosis and the Enzymes Implicated in Its Cell Wall: A Link Between Mycobacterial Infection and ... In nonclinical assessments, fucoxanthin showed the capacity to notably inhibit the growth of Mycobacterium tuberculosis. Its ...
The symptoms of infection resemble those of M. tuberculosis. It is a member of the Mycobacterium tuberculosis complex. There ... M. africanum tuberculosis is treated with an identical regime to tuberculosis caused by M. tuberculosis. The overall rate of ... "Progression to Active Tuberculosis, but Not Transmission, Varies by Mycobacterium tuberculosis Lineage in The Gambia". The ... March 2002). "A new evolutionary scenario for the Mycobacterium tuberculosis complex". Proc. Natl. Acad. Sci. U.S.A. 99 (6): ...
"Oral delivery of Mycobacterium bovis BCG in a lipid formulation induces resistance to pulmonary tuberculosis in mice". ... The technology is limited by the risk of systemic infections, adverse metabolic activities and the risk of gene transfer. ... Infection and Immunity. 71 (1): 101-108. doi:10.1128/IAI.71.1.101-108.2003. PMC 143408. PMID 12496154. Park JH, Um JI, Lee BJ, ... Pylori infections, atopic inflammations, lactose intolerance and immune modulation, amongst others. The proposed mechanism of ...