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*  Molecular cloning
... or make more subtle mutations using regional mutagenesis or site-directed mutagenesis. Obtaining the molecular clone of a gene ...
*  Mutagenesis
Directed mutagenesis Site-directed mutagenesis PCR mutagenesis Insertional mutagenesis Signature tagged mutagenesis Transposon ... Early methods of mutagenesis produced entirely random mutations; however, later methods of mutagenesis may produce site- ... Mutagenesis as a science was developed based on work done by Hermann Muller, Charlotte Auerbach and J. M. Robson in the first ... Mutagenesis may also arise as a result of the presence of environmental mutagens that induce changes to the DNA. The mechanism ...
*  Transposon mutagenesis
... is much more effective than chemical mutagenesis, with a higher mutation frequency and a lower chance of ... Transposon mutagenesis, or transposition mutagenesis, is a biological process that allows genes to be transferred to a host ... 2-2. Seifert, H S; Chen, E Y; So, M; Heffron, F (1986-02-01). "Shuttle mutagenesis: a method of transposon mutagenesis for ... Transposon mutagenesis was first studied by Barbara McClintock in the mid-20th century during her Nobel Prize-winning work with ...
*  Insertional mutagenesis
Directed mutagenesis Insertion (genetics) PCR mutagenesis Site-directed mutagenesis Transposon mutagenesis Biology-online Biffi ... Insertional mutagenesis is mutagenesis of DNA by the insertion of one or more bases. Insertional mutations can occur naturally ... mutagenesis caused by viral infections is a fairly common occurrence. Not all integrating viruses cause insertional mutagenesis ... Virus insertional mutagenesis is possible with both replication competent virus and the self-inactivating vectors that are ...
*  Cassette mutagenesis
... is a type of site-directed mutagenesis that uses a short, double-stranded oligonucleotide sequence (gene ... Unlike many site directed mutagenesis methods, cassette mutagenesis also does not involve primer extension by DNA polymerase. ... Compared to mutagenesis methods that requires the synthesis of double stranded DNA using a single stranded template (1-30% in ... Kegler-Ebo, D. M.; Docktor, C. M.; Dimaio, D (1994). "Codon cassette mutagenesis: A general method to insert or replace ...
*  Saturation mutagenesis
... is a random mutagenesis technique, in which a single codon or set of codons is randomised to produce all ... Sequence Saturation Mutagenesis Reetz, M. T.; Carballeira J. D. (2007). "Iterative saturation mutagenesis (ISM) for rapid ... Saturation mutagenesis is commonly achieved by artificial gene synthesis, with a mixture of nucleotides used at the codons to ... "Iterative Saturation Mutagenesis Accelerates Laboratory Evolution of Enzyme Stereoselectivity: Rigorous Comparison with ...
*  Directed mutagenesis
... was necessary for the directed mutagenesis observed by Cairns and colleagues in 1989. The directed mutagenesis hypothesis was ... Directed mutagenesis, also known as directed mutation, was a hypothesis proposing that organisms can respond to environmental ...
*  Sequence saturation mutagenesis
... (SeSaM) is a chemo-enzymatic random mutagenesis method applied for the directed evolution of ... "Transversion-enriched sequence saturation mutagenesis (SeSaM-Tv+): A random mutagenesis method with consecutive nucleotide ... Wong, T.S.; Tee, K.L.; Hauer, B.; Schwaneberg, U. (2004). "Sequence Saturation Mutagenesis (SeSaM): a novel method for directed ... 1. Wong, T.S.; Roccatano, D.; Zacharias, M.; Schwaneberg, U. (2006). "A statistical analysis of random mutagenesis methods used ...
*  Signature-tagged mutagenesis
... (STM) is a genetic technique used to study gene function. Recent advances in genome sequencing ... Saenz HL, Dehio C (October 2005). "Signature-tagged mutagenesis: technical advances in a negative selection method for ...
*  Site-directed mutagenesis
Also called site-specific mutagenesis or oligonucleotide-directed mutagenesis, it is used for investigating the structure and ... Nobel Lecture on Invention of Site-Directed Mutagenesis OpenWetWare Diagram summarizing site-directed mutagenesis. ... and mutagenesis may be performed in vivo with relative ease. Early attempts at mutagenesis using radiation or chemical mutagens ... These methods of mutagenesis, however, are limited by the kind of mutation they can achieve, and they are not as specific as ...
*  Mutagenesis (molecular biology technique)
... has also allowed for the editing or mutagenesis of the genome in vivo. Early approaches to mutagenesis rely on methods which ... Combinatorial mutagenesis is a technique whereby large number of mutants may be screened for a particular characteristic. In ... Insertional mutagenesis using transposons, retrovirus such as mouse mammary tumor virus and murine leukemia virus may be used ... Mutagenesis in the laboratory is an important technique whereby DNA mutations are deliberately engineered to produce mutant ...
*  DNA Repair and Mutagenesis
... is a college-level textbook about DNA repair and mutagenesis written by Errol Friedberg, Graham ... DNA repair and mutagenesis (2nd ed.). ASM Press. ISBN 978-1-55581-319-2. Eugene A. Davidson. "DNA repair and mutagenesis, Errol ... In its second edition as of 2009, DNA Repair and Mutagenesis contains over 1,000 pages, 10,000 references and 700 illustrations ...
*  Environmental Mutagenesis and Genomics Society
The initial aim was to support the study of environmental mutagenesis, originally in germ-cell mutagenesis, but the scope soon ... In 1979, the EMS began publishing its own journal, Environmental Mutagenesis, renamed Environmental and Molecular Mutagenesis ... Shelby, Michael D. (December 1978). "EMIC: A Centralized Source of Chemical Mutagenesis Information". Environmental Health ... "outstanding contributions in the application of the principles and techniques of environmental mutagenesis to the protection of ...
*  Decaffeination
Mutagenesis. 11 (6): 597-603. doi:10.1093/mutage/11.6.597. Savolainen, H (1992). "Tannin content of tea and coffee". J Appl ...
*  Cancer
Jacinto FV, Esteller M (July 2007). "Mutator pathways unleashed by epigenetic silencing in human cancer". Mutagenesis. 22 (4): ...
*  Tobacco smoking
Mutagenesis. 17 (3): 183-7. doi:10.1093/mutage/17.3.183. PMID 11971987. Pu X, Kamendulis LM, Klaunig JE (2009). "Acrylonitrile- ...
*  DNA repair
P Raychaudhury; Basu, Ashis K. (2011). "Genetic requirement for mutagenesis of the G[8,5-Me]T cross-link in Escherichia coli: ... Friedberg EC, Walker GC, Siede W, Wood RD, Schultz RA, Ellenberger T. (2006). DNA Repair and Mutagenesis, part 3. ASM Press. ... Paromita Raychaudhury and Ashis Basu studied the toxicity and mutagenesis of the same lesion in Escherichia coli by replicating ... Volkert MR (1988). "Adaptive response of Escherichia coli to alkylation damage". Environmental and Molecular Mutagenesis. 11 (2 ...
*  ERCC4
Mutagenesis. 4 (5): 349-54. doi:10.1093/mutage/4.5.349. PMID 2687628. Brookman KW, Lamerdin JE, Thelen MP, Hwang M, Reardon JT ... DNA Repair and Mutagenesis. ASM Press. ISBN 1555813194. "Entrez Gene: ERCC4 excision repair cross-complementing rodent repair ... Environmental and Molecular Mutagenesis. 51 (6): 520-6. doi:10.1002/em.20569. PMC 3017513 . PMID 20658645. Sargent RG, Rolig RL ... Environmental and Molecular Mutagenesis. 51 (6): 567-81. doi:10.1002/em.20583. PMID 20658648. Clauson C, Schärer OD, ...
*  Nondisjunction
Mutagenesis. 26 (3): 421-9. doi:10.1093/mutage/geq110. PMID 21273273. McHale CM, Smith MT, Zhang L (2014). "Application of ...
*  Colcemid
Mutagenesis. 28 (4): 457-464. doi:10.1093/mutage/get021. ISSN 0267-8357. PMID 23702691. Yamamoto, Mika; Wakata, Akihiro; Aoki, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 762: 10-16. doi:10.1016/j.mrfmmm.2014.02.002. ...
*  Erythrosine
Mutagenesis. 1 (4): 253-259. doi:10.1093/mutage/1.4.253. PMID 2457780. Jennings, A. S.; Schwartz S. L.; Balter N. J.; Gardner D ...
*  Mitotic catastrophe
Mutagenesis. 13: 337-44. PMID 9717169. Castedo M; Perfettini JL; Roumier T; Andreau K; Medema R; Kroemer G. (12 April 2004). " ...
*  3-Nitrobenzanthrone
Mutagenesis. 20 (6): 399-410. doi:10.1093/mutage/gei057. PMID 16199526. Fred Pearce (Oct 25, 1997). "Devil in the diesel". New ...
*  Extrachromosomal DNA
Shimizu, Noriaki (2011). "Molecular mechanisms of the origin of micronuclei from extrachromosomal elements". Mutagenesis. 26 (1 ...
*  Diesel exhaust
Mutagenesis. 20 (6): 399-410. doi:10.1093/mutage/gei057. PMID 16199526. Arlt, Volker M.; Glatt, Hansruedi; Muckel, Eva; Pabel, ...