When Mutagenesis Occurs[edit]. Germline mutations can occur before fertilization and during various stages of zygote ...
Site-directed mutagenesis[edit]. In 1971, Clyde Hutchison and Marshall Edgell showed that it is possible to produce mutants ... "The Development of Site-directed Mutagenesis by Michael Smith" (PDF). Journal of Biological Chemistry. 281 (39).. ... Clyde A. Hutchison III is an American biochemist and microbiologist notable for his research on site-directed mutagenesis and ... Hutchison, C.A. III; Swanstrom, R. & Loeb, D.D. (1991). "Complete Mutagenesis of Protein Coding Domains". Methods in Enzymology ...
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As discovered by site-directed mutagenesis, glutamate-268 is a key component of liver acetaldehyde dehydrogenase and is also ... aldehyde dehydrogenase as probed by site-directed mutagenesis". Biochemistry. 34 (1): 237-43. doi:10.1021/bi00001a028. PMID ...
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Mutagenesis 13(1): 1-8. PDF fulltext. *. Olive, P.L.; Wlodek, D. & Banath, J.P. (1991): DNA double-strand breaks measured in ... "Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 375 (2): 183-193. doi:10.1016/S0027-5107(97)00013-4. ... Environmental and Molecular Mutagenesis. 35 (3): 206-21. doi:10.1002/(SICI)10982280. PMID 10737956.. .mw-parser-output cite. ... Environmental and Molecular Mutagenesis 35(3): 206-221. doi:10.1002/(SICI)10982280 ...
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However, D. melanogaster also has importance in environmental research and mutagenesis. Being such great model organisms allows ... Mutation Research/Environmental Mutagenesis and Related Subjects. 85 (3): 141-146. doi:10.1016/0165-1161(81)90029-7. PMID ...
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