Kristy M. Ainslie
Ainslie, Kristy; Garanich, Jeffery; Dull, Randall; Tarbell, John (2005). "Vascular smooth muscle cell glycocalyx influences ... focusing on shear stress modulation of vascular smooth muscle cell contraction. Two years later in 2005, she completed her PhD ... Ainslie, Kristy; Shi, Z; Garanich, Jeffery; Tarbell, John (2004). "Rat aortic smooth muscle cells contract in response to serum ... Civelek, Mete; Ainslie, Kristy; Garanich, Jeffery; Tarbell, John (2002). "Smooth muscle cells contract in response to fluid ...
Theobromine
It is a bronchodilator and causes relaxation of vascular smooth muscle. It is not currently used as a prescription drug. The ... Also, chocolate may be a factor for heartburn in some people because theobromine may affect the esophageal sphincter muscle in ...
Durotaxis
The pathology of atherosclerosis is largely dependent on the migration of vascular smooth muscle cells (VSMCs) into the tunica ... Isenberg, BC; Dimilla, PA; Walker, M; Kim, S; Wong, JY (2 September 2009). "Vascular smooth muscle cell durotaxis depends on ... Rudijanto, A (2007). "The role of vascular smooth muscle cells on the pathogenesis of atherosclerosis". Acta Medica Indonesiana ... "Effect of substrate stiffness and PDGF on the behavior of vascular smooth muscle cells: Implications for atherosclerosis". ...
Alpha-2C adrenergic receptor
Mechanotaxis
"Directed Movement of Vascular Smooth Muscle Cells on Gradient-Compliant Hydrogels". Langmuir. 19 (5): 1908-1913. doi:10.1021/ ...
Tadalafil
PDE1 is found in the brain, heart, and vascular smooth muscle. It is thought that the inhibition of PDE1 by sildenafil and ... in smooth muscle cells.[medical citation needed] cGMP relaxes smooth muscle and increases blood flow to the corpus cavernosum.[ ... stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and the smooth muscle of ... PDE11 is expressed in skeletal muscle, the prostate, the liver, the kidney, the pituitary gland, and the testes. The effects on ...
Renal ultrasonography
They are composed of fat, smooth muscle tissue and vascular elements. The echogenicity is governed by the composition of these ... A solid renal mass appears in the US exam with internal echoes, without the well-defined, smooth walls seen in cysts, often ... Most renal masses are simple cortical renal cysts with a round appearance and a smooth thin capsule encompassing anechoic fluid ...
Vinpocetine
Hagiwara M, Endo T, Hidaka H (February 1984). "Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle ...
Traction force microscopy
"The contractile strength of vascular smooth muscle myocytes is shape dependent." Integrative Biology 6.2 (2014): 152-163. ...
Elizabeth Nabel
Gene therapy for vascular smooth muscle cell proliferation after arterial injury. Science 1994;265:781-784 Capell BC, Olive M, ... Nabel's studies on Hutchinson-Gilford progeria syndrome have characterized the vascular smooth muscle cell defect leading to ... and clarified the processes of cell division and growth of vascular smooth muscle cells in blood vessels. ... Her vascular biology laboratory characterized the role of cell cycle inhibitors on vascular proliferation and inflammation, and ...
Cl-formate exchanger
It is also present in vascular smooth muscle and cardiac muscle. Knauf, Felix; Yang, Chao-Ling; Thomson, R. Brent; Mentone, Sue ... Aronson Presence of chloride-formate exchange in vascular smooth muscle and cardiac cells M Soleimani and RL Howard. Department ...
MEF2B
"MEF2B-Nox1 signaling is critical for stretch-induced phenotypic modulation of vascular smooth muscle cells". Arteriosclerosis, ... MEF2B mRNA is present in skeletal, smooth, brain and heart muscles. MEF2B is directly involved in smooth muscle myosin heavy ... "MEF2B is a component of a smooth muscle-specific complex that binds an A/T-rich element important for smooth muscle myosin ... "MEF2B is a component of a smooth muscle-specific complex that binds an A/T-rich element important for smooth muscle myosin ...
Birthmark
They are caused by overgrowth of blood vessels, melanocytes, smooth muscle, fat, fibroblasts, or keratinocytes. Dermatologists ... A little over 1 in 10 babies have a vascular birthmark present by age 1. Several birthmark types are part of the group of skin ... Vascular birthmarks, also called red birthmarks, are caused by increased blood vessels and include macular stains (salmon ... Vascular birthmarks may require reduction or removal for cosmetic reasons. Treatments include administering oral or injected ...
Adenosine A1 receptor
A1 receptors are also present in smooth muscle throughout the vascular system. The adenosine A1 receptor has been found to be ... Caffeine may reduce cerebral blood flow in premature infants, it is presumed by blocking vascular A2 ARs. Thus, it may prove ... Tawfik HE, Schnermann J, Oldenburg PJ, Mustafa SJ (March 2005). "Role of A1 adenosine receptors in regulation of vascular tone ...
SMTN
2001). "Identification and characterization of novel smoothelin isoforms in vascular smooth muscle". J. Vasc. Res. 38 (2): 120- ... development of a smooth muscle cell in vitro system and identification of a vascular variant". Cell Struct. Funct. 22 (1): 65- ... This gene encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress ... 1999). "A novel isoform of the smooth muscle cell differentiation marker smoothelin". J. Mol. Med. 77 (2): 294-8. doi:10.1007/ ...
Amrinone
PDE III is present in cardiac muscle, vascular smooth muscle and platelets. PDE III degrades the phosphodiester bond in cAMP to ... An increase in cAMP with the administration of amrinone in vascular smooth muscle produces vasodilation by facilitating calcium ... levels fall in vascular smooth muscle. This impairs relaxation in the vasculature and is a part of the vicious cycle of CHF. ... "Effects of Phosphodiesterase Inhibition on Skeletal Muscle Vasculature". American Journal of Cardiology. 3 (2): 27-30. doi: ...
RAR-related orphan receptor alpha
Migita H, Morser J, Kawai K (March 2004). "Rev-erbalpha upregulates NF-kappaB-responsive genes in vascular smooth muscle cells ... Lau P, Bailey P, Dowhan DH, Muscat GE (January 1999). "Exogenous expression of a dominant negative RORalpha1 vector in muscle ...
George Stouffer
"Thrombin and vascular smooth muscle cell proliferation: implications for atherosclerosis and restenosis". Seminars in ... Stouffer's laboratory has a long-standing interest in understanding the direct effects of thrombin on smooth muscle cells (SMC ... Stouffer's early studies examined the mechanisms by which soluble growth factors stimulate smooth muscle cell proliferation. ... and thrombin-induced proliferation of cultured smooth muscle cells". Circulation. 97 (9): 907-915. doi:10.1161/01.cir.97.9.907 ...
Irreversible electroporation
... novel technology for vascular smooth muscle cells ablation". PLOS ONE. 4 (3): e4757. Bibcode:2009PLoSO...4.4757M. doi:10.1371/ ... novel technology for vascular smooth muscle cells ablation". PLOS ONE. 4 (3): e4757. Bibcode:2009PLoSO...4.4757M. doi:10.1371/ ... Maor et el have demonstrated the safety and efficiency of IRE as an ablation modality for smooth muscle cells in the walls of ... In general muscle relaxants are administered, since even under general anesthetics, strong muscle contractions are induced by ...
Sergolexole
Koba S, Pakala R, Watanabe T, Katagiri T, Benedict CR (November 1999). "Vascular smooth muscle proliferation: synergistic ...
Sodium nitroprusside
Myosin light chains are involved in smooth muscle contraction. The result is vascular smooth muscle relaxation, which allow ... NO activates guanylate cyclase in vascular smooth muscle and increases intracellular production of cGMP. cGMP activates protein ... Apprehension Restlessness Confusion Dizziness Headache Somnolence Rash Sweating Thyroid suppression Muscle twitch Oliguria ...
Calcium-activated potassium channel subunit alpha-1
"A human calcium-activated potassium channel gene expressed in vascular smooth muscle". The American Journal of Physiology. 269 ... They control the contraction of smooth muscle and are involved with the electrical tuning of hair cells in the cochlea. BK ... BK channels are essential for the regulation of several key physiological processes including smooth muscle tone and neuronal ... activated K+ channel from smooth muscle". The Journal of Biological Chemistry. 269 (25): 17274-8. doi:10.1016/S0021-9258(17) ...
TMEM38A
These results are thought to reflect a role for TRIC-A in the excitability of vascular smooth muscle cells. TRIC-A has been ... "TRIC-A Channels in Vascular Smooth Muscle Contribute to Blood Pressure Maintenance". Cell Metabolism. 14 (2): 231-241. doi: ... implicated in the regulation of arterial blood pressure through regulating the excitability of vascular smooth muscle cells. ... is a monovalent cation channel in the SR and nuclear membranes of skeletal muscle cells, encoded by the transmembrane protein ...
Vasomotion
In this model, high gap junction coupling is present between the vascular smooth muscle cells, the endothelial cells and the ... Intracellular calcium (Ca2+) concentration exhibits periodic oscillations in vascular smooth muscle cells. This is thought to ... depolarization occurs in the endothelial layer at the same time as the underlying vascular smooth muscle. The cause of the ... a low ATP cycling state of prolonged force generation common in vascular smooth muscle. Finally, vasomotion has been shown to ...
Adeno-associated virus
AAV2 presents natural tropism towards skeletal muscles, neurons, vascular smooth muscle cells and hepatocytes. Three cell ... "Adeno-associated virus vector transduction of vascular smooth muscle cells in vivo". Physiological Genomics. 2 (3): 117-27. doi ... In mice, the AAV genome has been observed persisting for long periods of time in quiescent tissues, such as skeletal muscles, ... April 2003). "AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B". Blood. 101 (8): ...
Life extension
November 2020). "Reactive Oxygen Species: Modulators of Phenotypic Switch of Vascular Smooth Muscle Cells". International ... Administration of IGF-1Eb (mechanogrowth factor) stimulates proliferation of myoblasts and induces muscle hypertrophy. ... one way of multiple they can be detrimental is by inhibiting adaptation to exercise such as muscle hypertrophy (e.g. during ... Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging". The Journal of Nutrition. 151 (12): ...
Cystic duct
The outer fibromuscular layer contains smooth muscle continuous with that of the gallbladder; some of the smooth muscle extends ... The subepithelial layer consists of elastic connective tissue and is highly vascular; vessels that are adjacent to the ...
Endothelin A receptor
Lin HY, Kaji EH, Winkel GK, Ives HE, Lodish HF (April 1991). "Cloning and functional expression of a vascular smooth muscle ... "Endothelin-1 and ETA receptor expression in vascular smooth muscle cells from human placenta: a new ETA receptor messenger ... Molecular cloning of human endothelin receptors and their expression in vascular endothelial cells and smooth muscle cells]". ...
Rev-ErbA alpha
Migita H, Morser J, Kawai K (Mar 2004). "Rev-erbalpha upregulates NF-kappaB-responsive genes in vascular smooth muscle cells". ... In mouse smooth muscle cells, the protein up-regulates expression of interleukin 6 (IL-6) and cyclooxygenase-2. In humans, it ... In humans, NR1D1 (REV-ERBÉ‘) is highly expressed in the brain and metabolic tissues, including skeletal muscle, adipose tissue, ... the expression of genes involved in muscle cell differentiation and is expressed in a circadian manner in mouse skeletal muscle ...
NOX4
2004). "Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cells". Arterioscler. Thromb. Vasc. Biol ... 2005). "Human urotensin II is a novel activator of NADPH oxidase in human pulmonary artery smooth muscle cells". Arterioscler. ... 2002). "Cytochrome b558-dependent NAD(P)H oxidase-phox units in smooth muscle and macrophages of atherosclerotic lesions". ... H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle ...