Amanita gemmata
It is a toxic mushroom, containing ibotenic acid and muscimol, also found in many species in section Amanita of the Amanita ... Toxicity is suspected to be due to the presence of muscimol and ibotenic acid. Generally, symptoms of poisoning appear within ...
GABAA receptor positive allosteric modulator
In addition, these steroids might enhance the binding of muscimol and benzodiazepines to GABAA receptors. Structure- activity ... enhanced both stimulus-evoked inhibition and the effects of exogenously applied muscimol, which is a GABAA selective agonist. ...
CL-218,872
"Spatial learning deficits induced by muscimol and CL218,872: lack of effect of prenatal malnutrition". Nutritional Neuroscience ...
Quisqualamine
Quisqualic acid Muscimol Evans RH, Francis AA, Hunt K, Martin MR, Watkins JC (June 1978). "Quisqualamine, a novel gamma- ...
Dorsomedial hypothalamic nucleus
The inhibition of neuronal activation using muscimol in the DMH inhibited 85% of heart rate response and 68% of blood pressure ... Stotz-Potter, Elizabeth H.; Willis, Lynn R.; DiMicco, Joseph A. (February 1996). "Muscimol acts in dorsomedial but not ...
Nucleus raphe pallidus
Conversely, microinjections of muscimol, a GABA-a agonist, inhibit tachycardia in rats under air-stress stimuli. In both of ... Microinjection of muscimol into raphe pallidus suppresses tachycardia associated with air stress in conscious rats. Journal of ...
Convection enhanced delivery
"Convection Enhanced Delivery of Muscimol to Study the Pathophysiology Underlying the Clinical Features of Parkinson's Disease ...
Amanita muscaria
Almost no muscimol is excreted when pure ibotenic acid is eaten, but muscimol is detectable in the urine after eating A. ... Ibotenic acid and muscimol act like these neurotransmitters, muscimol being a potent GABAA agonist, while ibotenic acid is an ... Muscimol is the product of the decarboxylation (usually by drying) of ibotenic acid. Muscimol and ibotenic acid were discovered ... Ibotenic acid, a neurotoxin, serves as a prodrug to muscimol, with a small amount likely converting to muscimol after ingestion ...
Entheogenics and the Maya
Some of the psychoactive components of the plants were narcotic analgesics, psilocybin, mescaline, DMT, muscimol, and others.[ ...
Amanita regalis
Chemical analysis has shown that this species contains muscimol, the same psychoactive compound found in A. muscaria. Amanita ... Chemical analysis has shown that this species contains ibotenic acid and muscimol, the same toxic constituents as Amanita ...
GABA analogue
GABAA receptor partial agonist Muscimol - constituent of Amanita muscaria mushrooms; GABAA receptor agonist Nipecotic acid - ...
Eyeblink conditioning
Methods used to temporarily inactivate nervous tissue include use of a cooling probe (< 10 °C), and locally infusing Muscimol ... For example, Krupa (1993) inactivated lobule HVI with the GABAA receptor agonist Muscimol and found significant acquisition ...
Dissociation (psychology)
... muscimol, atropine, ibogaine, and minocycline. Psychoactive substances that cause temporary dissociation tend to be NMDA ...
Sleep onset
"Long-lasting insomnia induced by preoptic neuron lesions and its transient reversal by muscimol injection into the posterior ...
Mushroom
... contain the psychoactive compound muscimol. The muscimol-containing chemotaxonomic group of Amanitas contains no amatoxins or ...
Neuroscience of sleep
"Long-lasting insomnia induced by preoptic neuron lesions and its transient reversal by muscimol injection into the posterior ...
Amanita pantherina
The effects of muscimol and ibotenic acid most closely resemble that of a Z drug, like Ambien at high doses, and not a ... While ibotenic acid is mostly broken down into the body to muscimol, what remains of the ibotenic acid is believed[according to ... As with other wild-growing mushrooms, the ratio of ibotenic acid to muscimol depends on countless external factors, including: ... A. pantherina contains the psychoactive compounds ibotenic acid and muscimol, two psychoactive constituents which can cause ...
Amanita muscaria var. formosa
The effects of muscimol and ibotenic acid most closely resemble that of a Z drug, like Ambien at high doses, and not a ... Ibotenic acid is mostly broken down into the body to muscimol, but what remains of the ibotenic acid is believed[according to ... As with other wild-growing mushrooms, the ratio of ibotenic acid to muscimol depends on countless external factors, including: ... As with other Amanita muscaria, the formosa variety contains ibotenic acid, and muscimol, two psychoactive constituents which ...
Edible mushroom
... and hallucinations due to the presence of muscimol. Although present in A. muscaria, ibotenic acid is not in high enough ... with the former containing alkaloids such as muscimol and the latter predominately psilocybin. Both have the potential to ... with the former containing alkaloids such as muscimol and the latter predominately psilocybin. Edible mushrooms include many ...
Effects of stress on memory
When the researchers inactivated that brain region by administering Muscimol to the females, no gender differences in classical ...
Etazolate
... and muscimol". Life Sciences. 24 (9): 833-41. doi:10.1016/0024-3205(79)90367-9. PMID 449623. Zezula J, Slany A, Sieghart W ( ...
Amanita muscaria var. inzengae
The effects of muscimol and ibotenic acid most closely resemble that of any GABAergic compound, but with a dissociative effect ... As with other wild-growing mushrooms, the ratio of ibotenic acid to muscimol depends on countless external factors, including: ... As with other Amanita muscaria, the inzengae variety contains ibotenic acid, and muscimol, two psychoactive constituents which ... Ibotenic acid is mostly broken down into the body to muscimol, but what remains of the ibotenic acid is believed[according to ...
Psychopharmacology
Such drugs include various psychoactive mushrooms containing psilocybin or muscimol and cacti containing mescaline and other ...
Nefiracetam
It was able to potently inhibit 80% of muscimol binding to the GABAA receptor, although it failed to displace the remaining 20 ... of specific muscimol binding. Nefiracetam is able to reverse the amnesia caused by the GABAA receptor antagonists picrotoxin ...
Alan Rockefeller
... "known and possibly new types of psilocybin and muscimol mushrooms." Mycology is an underfunded field that relies more than many ...
Muscarine
... though the pharmacologically more relevant compound from this mushroom is the Z-drug-like alkaloid muscimol. A. muscaria ...
Hypothalamus
... and inactivation with muscimol prior to exposure to the context abolishes the defensive behavior. Therefore, the hypothalamus, ...
Inverse agonist
Agonists for GABAA receptors (such as muscimol) create a relaxant effect, whereas inverse agonists have agitation effects (for ...
C4H6N2O2
... a reagent used in organic chemistry Muscimol, the major psychoactive alkaloid present in many mushrooms of the genus Amanita ...
List of MeSH codes (D03)
... muscimol MeSH D03.383.129.462.580 - oxadiazoles MeSH D03.383.129.462.580.200 - 5-amino-3-((5-nitro-2-furyl)vinyl)-1,2,4- ...