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*  Muscimol
... converting to muscimol via decarboxylation. Muscimol is produced in the mushrooms Amanita muscaria (fly agaric) and Amanita ... While muscimol is normally thought of as a selective GABAA agonist, it is also a partial agonist at the GABAA-rho receptor, and ... Muscimol binds to the same site on the GABAA receptor complex as GABA itself, as opposed to other GABAergic drugs such as ... In A. muscaria, the layer just below the skin of the cap contains the highest amount of muscimol, and is therefore the most ...
*  Antiemetic
Muscimol is purported to have antiemetic activity. Ajwain is purported to be antiemetic. It is a popular spice in India, ... hoe 2#section1 Muscimol. Chemical Data Sheet[permanent dead link], Database of Hazardous Materials, CAMEO chemicals. ...
*  Amanita strobiliformis
It contains ibonetic acid or muscimol like Amanita muscaria and Amanita pantherina. The species can be found in light woods or ... ISBN 978-0-7216-0639-2. Ammirati Joseph F., Traquair James A.; Paul A. Horgen (1985). "11 (Ibonetic acid-muscimol)". Poisonous ...
*  Amanita muscaria var. guessowii
guessowii contains ibotenic acid and muscimol. The amount varies from mushroom to mushroom. http://www.amanitaceae.org/?Amanita ...
*  Ibotenic acid
Unlike muscimol, the principal psychoactive constituent of Amanita muscaria that is understood to cause sedation and delirium, ... In addition, due to in vivo decarboxylation into muscimol, it acts indirectly as a potent GABAA and GABAA-ρ receptor agonist. ... "Symptoms of ibotenic/muscimol poisoning (isoxazol poisoning)". Toxic Fungi of Western North America. MykoWeb. Retrieved 30 ... ibotenic acid's psychoactive effects are not known independent of it serving as a prodrug to muscimol. Ibotenic acid is an ...
*  Mushroom poisoning
Ibotenic acid: Decarboxylates into muscimol upon ingestion. The effects of muscimol vary, but nausea and vomiting are common. ... Muscimol intoxication is often considered unpleasant and undesirable, however, and as such has seen little recreational use ... Amanita pantherina, while containing the same hallucinogens as Amanita muscaria (e.g., ibotenic acid and muscimol), has been ... A. muscaria, the "Alice in Wonderland" mushroom, is known for the hallucinatory experiences caused by muscimol, but A. ...
*  Psychoactive Amanita mushroom
They contain isoxazoles like muscimol and/or ibotenic acid. Isoxazoles has been identified not only in Amanitas but also in ... Amanita pantherina contains the psychoactive compound muscimol, but is used as an entheogen much less often than its much more ... "Erowid Psychoactive Amanitas Vault : Info on Ibotenic Acid & Muscimol". www.erowid.org. "Amanita pantherina var. pantherina - ...
*  Isoguvacine
Gaboxadol Muscimol Wahab A, Heinemann U, Albus K (October 2009). "Effects of gamma-aminobutyric acid (GABA) agonists and a GABA ...
*  Muscarine
... the pharmacologically more relevant compound from this mushroom is muscimol. A. muscaria fruitbodies contain a variable dose of ...
*  Legal intoxicant
Amanita muscaria contains the active chemicals ibotenic acid and muscimol. It is usually boiled before being eaten and has been ...
*  R. Marthanda Varma
"Lidocaine and muscimol microinjections in subthalamic nucleus reverse parkinsonian symptoms". Brain: 2105-2118. doi:10.1093/ ...
*  Allopregnanolone
"Brain allopregnanolone regulates the potency of the GABAA receptor agonist muscimol". Neuropharmacology. 39 (3): 440-448. doi: ...
*  Rostral ventromedial medulla
MK-801 reduced the exaggeration of SP hyperalgesia induced by muscimol. Also, low doses of SP and intrathecal muscimol ... the GABA A agonist muscimol was tested in conjuncture with SP. Intrathecal muscimol significantly enhanced SP-induced ... Chronic administration of RVM SP or acute SP combined with intrathecal muscimol resulted in significantly higher levels of ... Intrathecal gabazine treatment before muscimol blocked the increase in phosphorylated NR1 expression. On- and off-cells were ...
*  Erminio Costa
... receptor agonist muscimol". Neuropharmacology. 39 (3): 440-448. doi:10.1016/s0028-3908(99)00149-5. ISSN 0028-3908. PMID ...
*  Muscazone
Ibotenic acid Muscimol Merck Index, 12th Edition, 6390 Robert Alan Lewis (1998). Lewis' Dictionary of Toxicology. CRC Press. p ...
*  Thiomuscimol
... is a GABAA receptor agonist which is structurally related to muscimol. Krogsgaard-Larsen, P; Hjeds, H; Curtis, DR ...
*  Legal status of psychoactive Amanita mushrooms
This is a list of the legality of muscimol mushrooms by country. "Therapeutic Goods Regulations". www.legislation.gov.au. " ...
*  GABAA receptor
Some such as muscimol and the z-drugs may also be hallucinogenic.[citation needed] Ligands which decrease receptor activation ... Also note that some GABAA agonists such as muscimol and gaboxadol do bind to the same site on the GABAA receptor complex as ... The active site of the GABAA receptor is the binding site for GABA and several drugs such as muscimol, gaboxadol, and ... Orthosteric agonists: GABA, gaboxadol, isoguvacine, muscimol, progabide, piperidine-4-sulfonic acid (partial agonist). ...
*  NMDA receptor antagonist
Farber, NB; Jiang, X; Dikranian, K; Nemmers, B (2003). "Muscimol prevents NMDA antagonist neurotoxicity by activating GABAA ... and muscimol. Since NMDA receptor overactivation is implicated in excitotoxicity, NMDA receptor antagonists have held much ...
*  Amanita persicina
This species contains variable amounts of the neuroactive compounds ibotenic acid and muscimol. Amanita muscaria var. persicina ...
*  Psychoactive drug
The muscimol-containing Amanita muscaria mushroom was used for ritual purposes throughout prehistoric Europe. The use of ...
*  Recreational drug use
... prodrug to muscimol) muscimol (also found in Amanita muscaria, a GABAergic) Dissociatives dextromethorphan (DXM; Robitussin, ... muscimol Amanita muscaria: ibotenic acid and muscimol Claviceps purpurea and other Clavicipitaceae: ergotamine (not ...
*  Between-systems memory interference model
The second group (Muscimol-Muscimol) had muscimol administrations again just before acquisition and retention. Because muscimol ... Using this paradigm, the rats were bilaterally injected with either muscimol or sterile physiological saline depending on if ...
*  Amanita gemmata
Toxicity is suspected to be due to the presence of muscimol and ibotenic acid. Generally, symptoms of poisoning appear within ...
*  GABAA receptor positive allosteric modulator
In addition, these steroids might enhance the binding of muscimol and benzodiazepines to GABAA receptors. Structure- activity ... enhanced both stimulus-evoked inhibition and the effects of exogenously applied muscimol which is a GABAA selective agonist. ...