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*  Muscarine
Other muscarinic antagonists are scopolamine and pirenzepine. Muscarinic antagonists dilate the pupil and relax the ciliary ... Muscarinic antagonists are often called parasympatholytics because they have the same effect as agents that block ... Muscarinic agonists activate muscarinic receptors while nicotinic agonists activate nicotine receptors. Both are direct-acting ... Cardiac ventricles contain muscarinic receptors that mediate a decrease in the force of contractions leading to a lower blood ...
*  Muscarinic antagonist
Effects of Muscarinic Antagonist Atropine (Muscarinic Receptor Antagonist), Cardiovascular Pharmacology Concepts, Richard E. ... A muscarinic receptor antagonist (MRA) is a type of anticholinergic agent that blocks the activity of the muscarinic ... Muscarinic antagonist effects and muscarinic agonist effects counterbalance each other for homeostasis. Certain substances are ... "Affinity profiles of various muscarinic antagonists for cloned human muscarinic acetylcholine receptor (mAChR) subtypes and ...
*  Antispasmodic
Muscarinic antagonist Parasympatholytic Phloroglucinol Spasticity "Antispasmodic". thefreedictionary.com. Retrieved February 1 ...
*  Propiverine
It is a muscarinic antagonist. A modified release preparation is also available, taken once daily. British Medical Journal ...
*  Trospium chloride
... is a muscarinic antagonist. Trospium chloride blocks the effect of acetylcholine on muscarinic receptors ... Receptor assays showed that trospium chloride has negligible affinity for nicotinic receptors as compared to muscarinic ...
*  Long-acting beta-adrenoceptor agonist
Umeclidinium bromide is a long-acting muscarinic antagonist. This combination was approved by the FDA on December 18, 2013 for ...
*  Treatments for overactive bladder
Most drugs used to treat overactive bladder are muscarinic antagonists. Consumer Reports Health Best Buy Drugs (June 2010). " ...
*  Clidinium bromide
... (INN) is an anticholinergic (specifically a muscarinic antagonist) drug. It may help symptoms of cramping and ... Clidinium inhibits muscarinic acetylcholine receptors on smooth muscles, secretory glands, and in the central nervous system to ...
*  Methoctramine
Watson, N.; Barnes, P.J.; Maclagan, J. (1992). "Actions of methoctramine, a muscarinic M2 receptor antagonist, on muscarinic ... Methoctramine is a polymethylene tetraamine that acts as a muscarinic antagonist. It preferently binds to the pre-synaptic ... Hence, the presence of the antagonist methoctramine provokes an increase of the heart rate. In marked contrast of the above, ... This mentioned toxicity has its origin in a non-muscarinic mechanism, and bears a strong resemblance to other anticholinergic ...
*  Fesoterodine
Its tolerability and side effects are similar to other muscarinic antagonists and as a new drug seems unlikely to make great ... Fesoterodine has the advantage of allowing more flexible dosage than other muscarinic antagonists. ...
*  Ligand binding assay
For example, various antagonists can bind to multiple types receptors. In the case of muscarinic antagonists, they can also ... On the other hand, such techniques are also available to create receptor antagonists in order to prevent further cascades. Such ... antagonist) that will prevent specific binding to occur. Specific binding types to ligand and receptor interactions: ...
*  Dexetimide
It is a muscarinic antagonist that is used to treat drug induced parkinsonism. Dexetimide was discovered at Janssen ...
*  Organophosphate poisoning
Atropine is a muscarinic antagonist, and thus blocks the action of acetylcholine peripherally. These antidotes are effective at ... When there is expression of muscarinic overstimulation due to excess acetylcholine at muscarinic acetylcholine receptors ... When there is an accumulation of ACh at autonomic ganglia synapses this causes overstimulation of muscarinic expression in the ... The effects of organophosphate poisoning on muscarinic receptors are recalled using the mnemonic SLUDGEM (salivation, ...
*  LY-293284
"Substituted naphthofurans as hallucinogenic phenethylamine-ergoline hybrid molecules with unexpected muscarinic antagonist ...
*  Diphenidol
... is a muscarinic antagonist employed as an antiemetic and as an antivertigo agent. It is not marketed in the United ... Recently, a series of selective mACh-receptor antagonists based on the Diphenidol molecule has been synthesized, but they have ...
*  Methylscopolamine bromide
... is a muscarinic antagonist structurally similar to the neurotransmitter acetylcholine. Its mechanism of action involves ... blocking the muscarinic acetylcholine receptors. Drugs.com: Methscopolamine Gennaro AR. Remington: The Science and Practice of ...
*  Nicotinic antagonist
Nicotinic acetylcholine receptor Nicotinic agonist Muscarinic acetylcholine receptor Muscarinic agonist Muscarinic antagonist P ... A nicotinic antagonist is a type of anticholinergic drug that inhibits the action of acetylcholine (ACh) at nicotinic ... ISBN 0-443-07145-4. Page 149 Nicotinic antagonists at the US National Library of Medicine Medical Subject Headings (MeSH). ...
*  Aclidinium bromide
... (INN) is a long-acting, inhaled muscarinic antagonist (LAMA) approved in the US on July 24, 2012 as a ... Skin reactions such as rash, as well as side effects that are typical of muscarinic antagonists (fast heart rate, palpitations ... It is expected that adverse effects of aclidinium increase if it is combined with other muscarinic antagonists. In clinical ... Aclidinium is a long-acting, reversible antagonist at muscarinic receptors, with similar affinity to all five subtypes, but ...
*  Ipratropium bromide
Ipratropium is a muscarinic antagonist, a type of anticholinergic, which works by causing smooth muscles to relax. Ipratropium ... It is a nonselective muscarinic antagonist, and does not diffuse into the blood, which prevents systemic side effects. ... It blocks muscarinic acetylcholine receptors, without specificity for subtypes, and therefore promotes the degradation of ...
*  Withania somnifera
It is also a building block of atropine, an anticholinergic drug prototypical of the muscarinic antagonist class. Cuscohygrine ...
*  Aclidinium/formoterol
... a long-acting muscarinic antagonist, and formoterol, a long-acting ╬▓2 agonist. "Duaklir Genuair". European Medicines Agency. ...
*  Effects of sleep deprivation on cognitive performance
Muscarinic antagonists, or chemicals that block ACh, impair spatial learning when administered prior to a training task among ...
*  Pralidoxime
... is often used with atropine (a muscarinic antagonist) to help reduce the parasympathetic effects of organophosphate ... Atropine, which is choice of drug to antagonise the muscarinic effects of organophosphates, is administered even before ...
*  Bronchoconstriction
Muscarinic antagonists (anti-cholinergics): Blocking the muscarinic acetylcholine receptors in pulmonary smooth muscle tissue ... These medications include short-acting muscarinic antagonists (SAMAs) such as ipratropium, and long-acting muscarinic ... These smooth muscle cells have muscarinic M3 receptors on their membrane. The activation of these receptors by acetylcholine ... antagonists (LAMA) such as tiotropium. Onset of action for SAMAs is typically between 30-60 minutes, making these drugs less ...
*  Hyperthermia
The use of anticholinergics, more specifically muscarinic antagonists are thought to cause mild hyperthermic episodes due to ...
*  Pre-B├Âtzinger complex
The suppression of muscarinic receptors and the activation of nicotinic receptors due to prenatal exposure to nicotine have ... most being selective agonists or antagonists to receptor subtypes on neurons in the vicinity. Since many of these neurons ... Activation of M3 muscarinic receptors by acetylcholine and NK1 by Substance P significantly increases NALCN currents, while ... Acetylcholine plays an important modulatory role on the respiratory system by altering nicotinic and muscarinic receptors. ...