Quaternary structure Protein complex Macromolecular assembly Biomolecular complex Neuman, Nicole (2016). "The Complex ... Multienzyme complex carries out a single or a series of biochemical reactions taking place in the cells. It allows to segregate ... A multienzyme complex that functions in the histidine biosynthesis pathway has been studied at the biochemical and genetic ... Multienzyme complex contains several copies of one or several enzymes (polypeptide chains) packed into one assembly. ...
... s are multi-enzyme extracellular complexes. Cellulosomes are associated with the cell surface and mediate cell ... Cellulosome complexes are intricate, multi-enzyme machines, produced by many cellulolytic microorganisms. They are produced by ... The birth of the discrete, multi-enzyme cellulosome complex was thus documented. Currently known cellulosome-producing ... Cellulosomes exist as extracellular complexes that are either attached to the cell wall of bacteria or free in solution, where ...
Multi-enzyme complexes are likely to have more intricate regulatory mechanisms, and studies have already probed such processes ... More recent work on the regulation of eukaryotic PRK has focused on its ability to form multi-enzyme complexes with other ... Avilan L, Gontero B, Lebreton S, Ricard J (December 1997). "Information transfer in multienzyme complexes--2. The role of Arg64 ... Rault M, Gontero B, Ricard J (May 1991). "Thioredoxin activation of phosphoribulokinase in a chloroplast multi-enzyme complex ...
Leopoldseder S, Hettwer S, Sterner R (November 2006). "Evolution of Multi-Enzyme Complexes: The Case of Tryptophan Synthase". ... "Three-dimensional structure of the tryptophan synthase alpha 2 beta 2 multienzyme complex from Salmonella typhimurium". The ... TrpB2i formed transient complexes with TrpA and in the process activated TrpA unidirectionally. The other copy remained outside ... Subunits: Tryptophan synthase typically exists as an α-ββ-α complex. The α and β subunits have molecular masses of 27 and 43 ...
Kresge, Nicole; Robert D. Simoni; Robert L. Hill (21 August 2009). "Multienzyme Complexes and Hydrogen Transfer: the Work of ...
... is an enzyme component of the multienzyme pyruvate dehydrogenase complex. The pyruvate dehydrogenase complex is responsible for ... de Kok A, Hengeveld AF, Martin A, Westphal AH (Jun 1998). "The pyruvate dehydrogenase multi-enzyme complex from Gram-negative ... "Atomic structure of the cubic core of the pyruvate dehydrogenase multienzyme complex". Science. 255 (5051): 1544-50. Bibcode: ... Typically PDH is the result of a mutation in the X-linked gene for the E1 subunit of the pyruvate dehydrogenase complex. ...
"Mutations in sialidosis impair sialidase binding to the lysosomal multienzyme complex". J. Biol. Chem. 276 (20): 17286-90. doi: ... "Association of N-acetylgalactosamine-6-sulfate sulfatase with the multienzyme lysosomal complex of beta-galactosidase, ... In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter ... sialidase molecular defects in sialidosis patients suggests the structural organization of the lysosomal multienzyme complex". ...
... function and relationship in other ribonucleolytic multienzyme complexes". Biochem. Soc. Trans. 30 (2): 150-5. doi:10.1042/ ... The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein intracellular complex capable of ... Exosome complexes are found in both eukaryotic cells and archaea, while in bacteria a simpler complex called the degradosome ... In yeast, Rrp44 is associated with all exosome complexes and has a crucial role in the activity of the yeast exosome complex. ...
The composition of this multienzyme may vary depending on the organism. The multiprotein complex RNA degradosome in E. coli ... it is really difficult for RNA to scape from the complex. The RNA degradosome is a huge multi-enzyme association that is ... function and relationship in other ribonucleolytic multienzyme complexes". Biochemical Society Transactions. 30 (2): 150-5. doi ... This multi-protein complex is stimulated by a non-coding RNA, called miRNA in Eukaryotic cells and sRNA in bacteria. Small ...
... exonucleases in mammalian multienzyme DNA polymerase complexes]". Mol. Biol. (Mosk.). 36 (6): 1055-61. PMID 12500544. Shevelev ...
Spring, S (2014). "Function and Evolution of the Sox Multienzyme Complex in the Marine Gammaproteobacterium Congregibacter ... When grown in culture, C. litoralis KT71 has a generation time of 4.5 hours and prefers to grow on complex substrates where the ... used direct plating on complex low-nutrient media called MPM developed by Schut et al. MPM was designed to mimic seawater. ... and fatty acids as well as more complex substrates like yeast extract and trypticase peptone. Within its genome, genes, ...
Synthesis is conducted by multienzyme complexes, including peptide synthetases, polypeptide synthases, and tailoring enzymes. ... At the molecular level and in further detail, nodularin is processed in a complex manner to induce toxic effects. During ...
The purinosome is a putative multi-enzyme complex that carries out de novo purine biosynthesis within the cell. It is ... Thus far, isolation of a multienzyme complex inclusive of all purine biosynthesis enzymes has not been achieved. Purinosome ... The enzymes of the multi-step de novo purine biosynthesis pathway have been postulated to form a multi-enzyme complex to ... "Dynamic regulation of a metabolic multi-enzyme complex by protein kinase CK2". J Biol Chem. 285 (15): 11093-11099. doi:10.1074/ ...
Some studies have suggested the SBPase may be part of a large (900 kDa) multi-enzyme complex along with a number of other ... Suss KH, Arkona C, Manteuffel R, Adler K (June 1993). "Calvin cycle multienzyme complexes are bound to chloroplast thylakoid ... "Origin and distribution of Calvin cycle fructose and sedoheptulose bisphosphatases in plantae and complex algae: a single ... secondary origin of complex red plastids and subsequent propagation via tertiary endosymbioses". Protist. 158 (3): 263-76. doi: ...
This multi-enzyme complex is related structurally and functionally to the oxoglutarate dehydrogenase and branched-chain oxo- ... acid dehydrogenase multi-enzyme complexes. The reaction catalysed by pyruvate dehydrogenase complex is: The E1 subunit, called ... Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that converts pyruvate into acetyl-CoA by a process called ... stearothermophilus pyruvate dehydrogenase multienzyme complex and implications for eucaryote evolution". Cell. 17 (1): 85-93. ...
"Purification and partial characterization of the glycine decarboxylase multienzyme complex from Eubacterium acidaminophilum". ...
"Purification and characterization of a cellulolytic multienzyme complex produced by Neocallimastix patriciarum J11". ... "Purification and characterization of a cellulolytic multienzyme complex produced by Neocallimastix patriciarum J11". ...
Enzymes taking part in IMP synthesis constitute a multienzyme complex in the cell. Evidence demonstrates that there are ... The inosinate synthesis is complex, beginning with a 5-phosphoribosyl-1-pyrophosphate (PRPP). ...
Mowbray J, Moses V (June 1976). "The tentative identification in Escherichia coli of a multienzyme complex with glycolytic ... Consequently, the importance of these complexes for metabolism in general remains unclear. Some protein complexes contain a ... Srere PA (1987). "Complexes of sequential metabolic enzymes". Annu. Rev. Biochem. 56: 89-124. doi:10.1146/annurev.bi.56.070187. ... The cytosol is a complex mixture of substances dissolved in water. Although water forms the large majority of the cytosol, its ...
... a bacterial dehydrogenase in a multienzyme complex". FEBS Letters. 168 (2): 217-221. doi:10.1016/0014-5793(84)80249-5. ISSN ...
This enzyme is required for the complete reaction of at least five different multi-enzyme complexes. Additionally, DLD is a ... In these complexes, DLD converts dihydrolipoic acid and NAD+ into lipoic acid and NADH. DLD also has diaphorase activity, being ... November 2003). "Reduction of Fe(III) ions complexed to physiological ligands by lipoyl dehydrogenase and other flavoenzymes in ... "Organization of the cores of the mammalian pyruvate dehydrogenase complex formed by E2 and E2 plus the E3-binding protein and ...
in Russian)[2] Kurganov B.I., Lyubarev A.E. Enzymes and multienzyme complexes as controllable systems. In: Soviet Scientific ... In Chaetomium thermophilum, a complex of a metabolon exists between fatty acid synthase and a MDa carboxylase, and was observed ... This hypothesis was well accepted in the former USSR and further developed for the complex of glycolytic enzymes (Embden- ... in Russian) [1]. Kurganov B. I, Lyubarev A. E. Hypothetical structure of the complex of glycolytic enzymes (glycolytic ...
Aspartyl-tRNA synthetase (DARS) is part of a multienzyme complex of aminoacyl-tRNA synthetases. Aspartyl-tRNA synthetase ... 1999). "Genetic dissection of protein-protein interactions in multi-tRNA synthetase complex". Proc. Natl. Acad. Sci. U.S.A. 96 ... Norcum MT (1991). "Structural analysis of the high molecular mass aminoacyl-tRNA synthetase complex. Effects of neutral salts ... 2002). "Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex". Biochem. Biophys ...
His PhD thesis, titled "Multienzyme organization of encephalomyocarditis virus replication complexes", was supervised by Vadim ...
It is a multienzyme complex which possesses alpha-L-rhamnosidase and beta glucosidase active centers. The E.C. No.(EC 3.2.1.40 ...
"Action of multi-enzyme complex on protein extraction to obtain a protein concentrate from okara". Journal of Food Science and ... protein composition and does not require significant investment in complex machinery. Alkali extraction has been employed with ... Molecular formula assignment software for ultrahigh resolution mass spectrometry analysis of environmental complex mixtures". ...
"Long patch base excision repair proceeds via coordinated stimulation of the multienzyme DNA repair complex". The Journal of ...
This enzyme is also part of a larger multienzyme complex that channels the intermediates in the catalysis between subunits of ... This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2- ... "Crystal structure of the E1 component of the Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex". Journal of ... "Reduction in the E2k subunit of the alpha-ketoglutarate dehydrogenase complex has effects independent of complex activity". The ...
Such enzymes are usually secreted as part of multienzyme complexes that may include dockerins and carbohydrate-binding modules ... In plants cellulose is synthesized at the plasma membrane by rosette terminal complexes (RTCs). The RTCs are hexameric protein ... "Immunogold labeling of rosette terminal cellulose-synthesizing complexes in the vascular plant vigna angularis". The Plant Cell ...
Guiral M, Tron P, Aubert C, Gloter A, Iobbi-Nivol C, Giudici-Orticoni MT (Dec 2005). "A membrane-bound multienzyme, hydrogen- ... oxidizing, and sulfur-reducing complex from the hyperthermophilic bacterium Aquifex aeolicus". The Journal of Biological ...
The protein encoded by the human PDHA2 gene is part of the pyruvate dehydrogenase multienzyme complex. The entire human complex ... The E1 complex specifically uses the TPP cofactor to cleave the Calpha-C(=O) bond of pyruvate, and then transfer the acetyl ... Overall the complex catalyzes five reactions, with the overall reaction being: Pyruvate + CoA + NAD+ → acetyl-CoA + CO2 There ... The pyruvate dehydrogenase complex is responsible for the oxidative decarboxylation of pyruvate, with the final product being ...
April 2002). "Structure of the pyruvate dehydrogenase multienzyme complex E1 component from Escherichia coli at 1.85 A ... While defects have been identified in all 3 enzymes of the complex, the E1-α subunit is predominantly the culprit. Malfunction ... Pyruvate Dehydrogenase Complex Deficiency at eMedicine Recny MA, Hager LP (1982). "Reconstitution of native Escherichia coli ... Pyruvate dehydrogenase is usually encountered as a component, referred to as E1, of the pyruvate dehydrogenase complex (PDC). ...