"Host cell cathepsins potentiate Moloney murine leukemia virus infection". Journal of Virology. 81 (19): 10506-14. doi:10.1128/ ...
Human immunodeficiency virus type 1 and Moloney murine leukemia virus enzymes prefer to cleave the RNA strand one nucleotide ... "Crystal structure of the moloney murine leukemia virus RNase H domain". Journal of Virology. 80 (17): 8379-89. doi:10.1128/jvi. ... Taylor JM (March 1977). "An analysis of the role of tRNA species as primers for the transcription into DNA of RNA tumor virus ... Leo B, Schweimer K, Rösch P, Hartl MJ, Wöhrl BM (September 2012). "The solution structure of the prototype foamy virus RNase H ...
Coffin, JM; Hageman RC; Maxam AM; Haseltine WA (1978). "Structure of the Genome of Moloney Murine Leukemia Virus: A Terminally ... Rose, J; Haseltine WA; Baltimore D (1976). "5'-Terminus of Moloney Murine Leukemia Virus 35s RNA is m7G5ppp5'GmpCp". Journal of ... Haseltine, WA; Coffin JM; Hageman TC (1979). "Structure of Product of the Moloney Murine Leukemia Virus Endogenous DNA ... "Identification of RNA Primer of DNA Synthesis of Moloney Murine Leukemia Virus". Journal of Virology. 21 (3): 1031-41. doi: ...
"NMR structure of the 101-nucleotide core encapsidation signal of the Moloney murine leukemia virus". Journal of Molecular ... The Friend virus (FV) is a strain of murine leukemia virus. The Friend virus has been used for both immunotherapy and vaccines ... The murine leukemia viruses (MLVs or MuLVs) are retroviruses named for their ability to cause cancer in murine (mouse) hosts. ... The murine leukemia viruses are group/type VI retroviruses belonging to the gammaretroviral genus of the Retroviridae family. ...
"NMR structure of the 101-nucleotide core encapsidation signal of the Moloney murine leukemia virus". J Mol Biol. 337 (2): 427- ... D'Souza V, Summers MF (2004). "Structural basis for packaging the dimeric genome of Moloney murine leukaemia virus". Nature. ... signal is an RNA element known to be essential for stable dimerisation and efficient genome packaging during virus assembly. ...
"Proviral Integration Site for Moloney Murine Leukemia Virus (PIM) Kinases Promote Human T Helper 1 Cell Differentiation". The ... PIM2 or Proviral Integrations of Moloney virus 2 is serine/threonine kinase that has roles in cell growth, proliferation, ... "Increased Expression of the hPim-2 Gene In Human Chronic lymphocytic Leukemia and Non-Hodgkin Lymphoma". Leukemia & Lymphoma. ... The studies showed higher levels of expression in NHL over normal lymphocytes as well as in chronic lymphocytic leukemia over ...
Campbell, Andrew G. (July 2001). "Expression of Moloney Murine Leukemia Virus RNase H Rescues the Growth Defect of an ... As a President's Postdoctoral Fellow at UCSF Campbell studied Hepatitis B Virus with William J. Rutter, founder of the Chiron ...
... such as Moloney murine leukemia virus (MoMLV), feline leukemia virus (FLV), and feline sarcoma virus (FESV). This family also ... "Atomic resolution structure of Moloney murine leukemia virus matrix protein and its relationship to other retroviral matrix ... Matrix proteins are also components of beta-retroviruses such as Mason-Pfizer monkey virus (MPMV) and mouse mammary tumor virus ... Stansell E, Tytler E, Walter MR, Hunter E (May 2004). "An early stage of Mason-Pfizer monkey virus budding is regulated by the ...
A highly efficient helper virus commonly used when growing A-MuLV in vitro is Moloney murine leukemia virus (M-MuLV). It causes ... Shields A, Rosenberg N, Baltimore D (1979). "Virus production by Abelson murine leukemia virus-transformed lymphoid cells". J. ... The Abelson murine leukemia virus (Ab-MLV or A-MuLV) is a retrovirus (Class VI) used to induce malignant transformation of ... The Abelson murine leukemia virus is named for the American pediatrician Herbert T. Abelson, who together with Louise S ...
In the first system, a wild-type Moloney Murine Leukemia Virus (M-MLV) reverse transcriptase was fused to the Cas9 H840A ... A fusion protein consisting of a Cas9 H840A nickase fused to a Moloney Murine Leukemia Virus (M-MLV) reverse transcriptase. ... The target organism can then be transduced by the virus to synthesize the base editor in vivo. Common laboratory vectors of ... so proposed human therapies often centered around adeno-associated virus (AAV) because AAV infections are largely asymptomatic ...
M-MLV reverse transcriptase from the Moloney murine leukemia virus is a single 75 kDa monomer. AMV reverse transcriptase from ... murine leukemia virus and again Rous sarcoma virus. For their achievements, they shared the 1975 Nobel Prize in Physiology or ... Biology portal Viruses portal cDNA library DNA polymerase msDNA Reverse transcribing virus RNA polymerase Telomerase ... ISBN 978-0-87969-382-4. Bernstein A, Weiss R, Tooze J (1985). "RNA tumor viruses". Molecular Biology of Tumor Viruses (2nd ed ...
... purified as a sequence-specific DNA-binding protein that regulated the disease specificity of the Moloney murine Leukemia virus ... a protein that binds the conserved core site in murine leukemia virus enhancers". Mol Cell Biol. 12 (1): 89-102. doi:10.1128/ ... "Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor". Mol ... Perry C, Eldor A, Soreq H (March 2002). "Runx1/AML1 in leukemia: disrupted association with diverse protein partners". Leukemia ...
A few examples of the virus are Moloney murine leukemia virus, xenotropic MuLB-related virus, feline leukemia virus, and feline ... Example species are the murine leukemia virus and the feline leukemia virus. They cause various sarcomas, leukemias and immune ... over 50 human cancer cell lines that were claimed to be linked to murine leukemia virus-related virus or murine leukemia virus ... One specific gammaretrovirus that is commonly used as a retroviral vector is the Moloney murine leukemia virus. A specific ...
The recombinant retroviruses such as the Moloney murine leukemia virus have the ability to integrate into the host genome in a ... This concern remained theoretical until gene therapy for ten SCID-X1 patients using Moloney murine leukemia virus resulted in ... Tobacco mosaic virus (TMV) is the first virus to be discovered. Viral vectors based on tobacco mosaic virus include those of ... Adeno-associated virus (AAV) is a small virus that infects humans and some other primate species. AAV is not currently known to ...
"Oligomerization and transport of the envelope protein of Moloney murine leukemia virus-TB and of ts1, a neurovirulent ... For the virus to penetrate the cytosol of a host cell, a low pH is necessary. The env gene of Murine Leukemia Virus (MLV) codes ... The Env proteins of the Avian Sarcoma and Leukosis virus (ASLV) and the Murine Leukemia Virus (MLV) are both trimers of SU-TM ... This membrane receptor was isolated from Rauscher murine leukemia virus (R-MuLV). The retroviral protein env has been captured ...
The main use of BOSC 23 is the production of recombinant retroviruses; it stably expresses Moloney murine leukemia virus ... The cell line does not produce detectable replication-competent virus, an important safety feature.[citation needed] BOSC 23 ...
The earliest retroviral vectors were based on the Moloney murine leukemia virus (MMLV) which when pseudotyped with GaLV ... "The receptors for gibbon ape leukemia virus and amphotropic murine leukemia virus are not downregulated in productively ... "Gibbon ape leukemia virus-Hall's Island: new strain of gibbon ape leukemia virus". Journal of Virology. 29 (1): 395-400. doi: ... J, McKee; N, Clark; F, Shapter; G, Simmons (April 2017). "A New Look at the Origins of Gibbon Ape Leukemia Virus". Virus Genes ...
... has been seen to demonstrate antiviral activity against a number of viruses including Moloney murine leukemia virus, ... Rauscher murine leukemia virus, and the human immunodeficiency virus. Its effects against the proliferation of viruses is ... Myricetin was identified as a competitive inhibitor of the reverse transcriptase of Rauscher murine leukemia virus and a ... "Myricetin-induced oxidative stress suppresses murine T lymphocyte activation". Cell Biology International. 42 (8): 1069-1075. ...
The M-MLV reverse transcriptase from the Moloney murine leukemia virus is commonly used due to its reduced RNase H activity ... Some viruses also use cDNA to turn their viral RNA into mRNA (viral RNA → cDNA → mRNA). The mRNA is used to make viral proteins ... Here, the host cell membrane becomes attached to the virus' lipid envelope which allows the viral capsid with two copies of ... This mechanism is shared with viruses with the exclusion of the generation of infectious particles. cDNA library - Type of DNA ...
... immunodeficiency virus type 1 and simian immunodeficiency virus and to the p12Gag protein of Moloney murine leukemia virus". ... Mazzé FM, Degrève L (2006). "The role of viral and cellular proteins in the budding of human immunodeficiency virus". Acta ... Unanchored ubiquitin in virus uncoating". Science. 346 (6208): 427-8. doi:10.1126/science.1261509. PMID 25342790. S2CID ...
... as it was the locus most frequently activated by the Moloney murine leukemia virus. Subsequently, the oncogene has been ... a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials ... Human, murine and rat Pim-1 contain 313 amino acids, and have a 94 - 97% amino acid identity. The active site of the protein, ... The pim-1 oncogene was first described in relation to murine T-cell lymphomas, ...
... immunodeficiency virus type 1 and simian immunodeficiency virus and to the p12Gag protein of Moloney murine leukemia virus". ... Mazzé FM, Degrève L (2006). "The role of viral and cellular proteins in the budding of human immunodeficiency virus". Acta ... Gottwein E, Kräusslich HG (Jul 2005). "Analysis of human immunodeficiency virus type 1 Gag ubiquitination". Journal of Virology ...
B cell-specific Moloney murine leukemia virus integration site 1). BMI1 is a polycomb ring finger oncogene. BMI1 (B lymphoma Mo ... a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex". J ...
... moloney murine leukemia virus MeSH B04.820.650.375.525.750 - radiation leukemia virus MeSH B04.820.650.375.525.770 - rauscher ... leukemia virus, feline MeSH B04.820.650.375.510 - leukemia virus, gibbon ape MeSH B04.820.650.375.525 - leukemia virus, murine ... moloney murine leukemia virus MeSH B04.909.574.807.375.525.750 - radiation leukemia virus MeSH B04.909.574.807.375.525.770 - ... moloney murine leukemia virus MeSH B04.909.777.731.375.525.750 - radiation leukemia virus MeSH B04.909.777.731.375.525.770 - ...
"Murine leukemia virus reverse transcriptase: structural comparison with HIV-1 reverse transcriptase". Virus Research. 134 (1-2 ... "Insight into the mechanism of the stabilization of moloney murine leukaemia virus reverse transcriptase by eliminating RNase H ... Retroviral RT proteins from HIV-1 and murine leukemia virus are the best-studied members of the family. Retroviral RT is ... Pathogenic examples include human immunodeficiency virus and hepatitis B virus, respectively. Both encode large multifunctional ...
... including Murine leukemia virus and Feline leukemia virus Genus Deltaretrovirus; including Bovine leukemia virus and the cancer ... One difficulty faced with some retroviruses, such as the Moloney retrovirus, involves the requirement for cells to be actively ... causing a type of leukemia in humans, and murine leukemia viruses (MLVs) in mice. Lentiviruses (slow viruses) include HIV-1 and ... Some viruses contain additional genes. The lentivirus genus, the spumavirus genus, the HTLV / bovine leukemia virus (BLV) genus ...
CB5A Murciavirus CPP1m Murine coronavirus Murine leukemia virus Murine mastadenovirus A Murine mastadenovirus B Murine ... contagiosum virus Mollymurvirus mollymur Mollyvirus colly Mollyvirus molly Moloevirus chthonenecus Moloney murine sarcoma virus ... virus A Potato virus H Potato virus M Potato virus P Potato virus S Potato virus T Potato virus V Potato virus X Potato virus Y ... Garlic mite-borne filamentous virus Garlic virus A Garlic virus B Garlic virus C Garlic virus D Garlic virus E Garlic virus X ...
Young, Neal S. Viruses and Bone Marrow: Basic Research and Clinical Practice. New York: M. Dekker, 1993. Young, Neal S., and ... Efficacy of JAK1/2 inhibition in murine immune bone marrow failure. Blood. 2023 Jan 5;141(1):72-89. Web Page at NIH NS Young, ... He later found that telomerase mutations also are a risk factor for acute myeloid leukemia and hepatic liver cirrhosis. In his ... Moloney Lectureship, Brigham and Women's Hospital, Harvard Medical School, Boston, 2009 Outstanding Work in Science as Related ...
Cytotoxic cells with specificity for mouse Moloney leukemia cells. Characteristics of the killer cell". European Journal of ... Chikungunya virus, HIV, or viral hepatitis. However, whether these virus infections trigger the expansion of adaptive NKG2C+ NK ... In mice, the majority of research was carried out with murine cytomegalovirus (MCMV) and in models of hapten-hypersensitivity ... It has been shown that this kind of NK cell has enhanced interferon-γ production and cytotoxicity against leukemia cell lines ...