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*  Molecular mimicry
The prerequisite for molecular mimicry to occur is thus the sharing of the immunodominant epitope between the pathogen and the ... Molecular mimicry, from these examples, has therefore been shown to occur in the absence of any true sequence homology. There ... Molecular mimicry has been characterized as recently as the 1970s as another mechanism by which a pathogen can generate ... Molecular mimicry is, however, only one mechanism by which an autoimmune disease can occur in association with a pathogen. ...
*  Betty Diamond
Molecular Mimicry, Microbes and Autoimmunity. (editors) M.W. Cunningham and R.S. Fujinami. ASM press. Chapter 10:127-141. (2000 ... Molecular mimicry: anti-DNA antibodies bind microbial and non-nucleic acid self-antigens. In Encyclopedi of Neuroimmunology, ... Molecular Immunol. 42:811-820 (2005). Davidson, A., Diamond, B., Wofsy, D., and Daikh D. Block and tackle: CTLA4Ig takes on ... Molecular Immunology 32:130-2 (2011). Yildirm-Toruner, C. and Diamond, B. Novel Therapeutics in Treatment of SLE. J Allergy and ...
*  Anti-dsDNA antibodies
... can also be produced through infection via a mechanism known as molecular mimicry. Upon exposure to ... Poole BD, Scofield RH, Harley JB, James JA (February 2006). "Epstein-Barr virus and molecular mimicry in systemic lupus ... Blank M, Barzilai O, Shoenfeld Y (February 2007). "Molecular mimicry and auto-immunity". Clin Rev Allergy Immunol. 32 (1): 111- ...
*  Lyme disease
The production of this reaction might be due to a form of molecular mimicry, where Borrelia avoids being killed by the immune ... Oldstone MB (October 1998). "Molecular mimicry and immune-mediated diseases" (PDF). FASEB J. 12 (13): 1255-65. PMID 9761770. ... Bolz DD, Weis JJ (August 2004). "Molecular mimicry to Borrelia burgdorferi: pathway to autoimmunity?". Autoimmunity. 37 (5): ... primary source) Auwaerter PG, Aucott J, Dumler JS (January 2004). "Lyme borreliosis (Lyme disease): molecular and cellular ...
*  Clonal deletion
It is possible, but uncommon for molecular mimicry to lead to an autoimmune disease. Superantigens are composed of viral or ... Complete clonal deletion can lead to opportunities for molecular mimicry, which has adverse effects for the host. Therefore, ... Rose, Noel R. (2015-06-21). "Molecular Mimicry and Clonal Deletion: A Fresh Look". Journal of Theoretical Biology. 375: 71-76. ...
*  Behavior-altering parasite
Other sources suggest a possible origin in molecular mimicry. Mermithid nematodes infect arthropods, residing in their ...
*  Rheumatic fever
... but it is known to involve molecular mimicry and genetic predisposition that lead to autoimmune reactions. Molecular mimicry ... In RHD, molecular mimicry results in incorrect T cell activation, and these T lymphocytes can go on to activate B cells, which ... This cross-reactivity is a type II hypersensitivity reaction and is termed molecular mimicry. Usually, self reactive B cells ... Guilherme, L; Kalil, J; Cunningham, M (2006). "Molecular mimicry in the autoimmune pathogenesis of rheumatic heart disease". ...
*  Aggressive mimicry
Treated separately is molecular mimicry, which also shares some similarity; for instance a virus may mimic the molecular ... Aggressive mimicry stands in semantic contrast with defensive mimicry, where it is the prey that acts as a mimic, with ... Aggressive mimicry is a form of mimicry in which predators, parasites or parasitoids share similar signals, using a harmless ... In Batesian mimicry, the mimic is modeled on a dangerous (usually unpalatable) species, while in Müllerian mimicry both species ...
*  Lipopolysaccharide
The molecular mimicry of some LOS molecules is thought to cause autoimmune-based host responses, such as flareups of multiple ... Furthermore, LOS molecules are responsible for the ability of some bacterial strains to display molecular mimicry and antigenic ... Moran AP, Prendergast MM, Appelmelk BJ (1996). "Molecular mimicry of host structures by bacterial lipopolysaccharides and its ... "Molecular mimicry as an inducing trigger for CNS autoimmune demyelinating disease". Immunol. Rev. 245 (1): 227-38. doi:10.1111/ ...
*  Chemorepulsion
1996). "Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV". Science. 274 (5293): 1739-1744. doi: ... 1998). "Molecular mimicry of the inflammation modulatory proteins (IMPs) of poxviruses: evasion of the inflammatory response to ... doi:10.1111/j.1600-065X.1999.tb01293.x. Murphy, PM (1994). "Molecular piracy of chemokine receptors by herpesviruses". Infect ... Kotwal, GJ (2000). "Poxviral mimicry of complement and chemokine system components: what's the end game?". Immunol Today. 21 (5 ...
*  Autoimmunity
The idea of molecular mimicry arose in the context of Rheumatic Fever, which follows infection with Group A beta-haemolytic ... In contrast to molecular mimicry, the other epitopes need not be structurally similar to the primary one. Epitope modification ... Molecular Mimicry - An exogenous antigen may share structural similarities with certain host antigens; thus, any antibody ... Although rheumatic fever has been attributed to molecular mimicry for half a century no antigen has been formally identified ( ...
*  Human herpesvirus 6
The molecular mimicry hypothesis, in which T cells are essentially confusing an HHV-6 viral protein with myelin basic protein, ... Their early research suggested that molecular mimicry may not be a mechanism that is involved in MS. A few months later, ... Although, a few mechanisms have been suggested: molecular mimicry, phosphorylation pathways, and cytokines. The first study to ... Arbuckle, Jesse H.; Medveczky, Peter G. (2011). "The molecular biology of human herpesvirus-6 latency and telomere integration ...
*  Vitamin B12 deficiency anemia
A long-standing H. pylori infection may cause gastric autoimmunity by a mechanism known as molecular mimicry. Antibodies ...
*  Interleukin 33
Roussel L, Erard M, Cayrol C, Girard JP (October 2008). "Molecular mimicry between IL-33 and KSHV for attachment to chromatin ... "Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules". The ...
*  Systemic scleroderma
It may also be caused by an immune reaction to a virus (molecular mimicry) or by toxins. The Juvenile Scleroderma Network is an ... Jimenez SA, Derk CT (2004). "Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis ...
*  Autoimmune disease
The concept of molecular mimicry describes a situation in which a foreign antigen can initiate an immune response in which a T ... Wucherpfennig KW, Strominger JL (1995). "Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T ...
*  AnkB F-Box
The presence of the F-box domain is an example of molecular mimicry of eukaryotic F-box by which Legionella exploits the ... Molecular mimicry by an F-Box Effector of Legionella pneumophila hijacks a conserved polyubiquitination machinery within ...
*  Anti-nuclear antibody
Molecular and epidemiological studies suggest that anti-Sm antibodies may be induced by molecular mimicry because the protein ... Molecular mimicry has also been suggested as a possible mechanism for the production of antibodies to these proteins because of ... The retroviral gag protein shows similarity to the La protein and is proposed as a possible example for molecular mimicry in ... The antibodies may also be produced through molecular mimicry, where cross reactive antibodies bind to both virus and human ...
*  Sjögren syndrome
Viral proteins, engulfed molecules, or degraded self-structures may initiate autoimmunity by molecular mimicry and increase the ... Reveille JD: The molecular genetics of systemic lupus erythematosus and Sjögren's syndrome. Curr Opin Rheumatol 1992, 4:644-656 ... Voulgarelis, Michael; Skopouli, Fotini N. (2007). "Clinical, immunologic, and molecular factors predicting lymphoma development ... and which specific molecular mechanisms are involved in the process of viral reactivation. Epithelial cells in SS lesions are ...
*  Harvey Cantor
Zhao ZS, Granucci F, Yeh L, Schaffer PA, Cantor H. Molecular mimicry by herpes simplex virus-1: Autoimmune disease after viral ... His laboratory continues to investigate the molecular and cellular elements that regulate the immune response and maintain self ...
*  Anti-neutrophil cytoplasmic antibody
... this is the theory of molecular mimicry. Staphylococcal and streptococcal superantigens have been characterised in autoimmune ...
*  APC Family
Simmons-Willis, TA; Koh, AS; Clarkson, TW; Ballatori, N (October 1, 2002). "Transport of a neurotoxicant by molecular mimicry: ... by molecular mimicry. Hip1 of S. cerevisiae (TC #2.A.3.1.5) has been implicated in heavy metal transport. Subfamilies of the ...
*  Myelin basic protein
... "molecular mimicry" hypothesis of multiple sclerosis has been suggested, in which T cells are, in essence, confusing MBP with ...
*  Major urinary proteins
The reason for this is not known, however molecular mimicry between Mups and structurally similar human lipocalins has been ... Mups are members of a large family of low-molecular weight (~19 kDa) proteins known as lipocalins. They have a characteristic ... Kurtz DT (1981). "Rat alpha 2u globulin is encoded by a multigene family". Journal of Molecular and Applied Genetics. 1 (1): 29 ... Robertson DH, Cox KA, Gaskell SJ, Evershed RP, Beynon RJ (1996). "Molecular heterogeneity in the Major Urinary Proteins of the ...
*  Klebsiella pneumoniae
Research conducted at King's College, London has implicated molecular mimicry between HLA-B27 and two Klebsiella surface ... and E. coli are: this facilitates performing the test in the microbiology laboratory without the use of molecular methods, and ...
*  Strikeforce: Morituri
John Crenella (Wildcard) - Power Mimicry (limited to copying the super powers of other Morituri); Died from the Morituri effect ... Burke O'Halloran (Hardcase) - Density control (limited to enhancing the molecular density of any object to make it nearly ... Aline Pagrovna (Blackthorn) - Disrupt molecular bonds, causing things to melt and break; During an encounter with Wildcard ( ... energy waves from hands that could slice through objects on the molecular level with a range of one meter; fell to his death in ...