Molecular modeling[edit]. Main article: Molecular modeling. Nonlinear optimization methods are widely used in conformational ... Gradient descent is used to update Weights in a Neural Network Model, i.e. update and tune the Model's parameters in a ... Also, agents are often modeled as being risk-averse, thereby preferring to avoid risk. Asset prices are also modeled using ... Space mapping is a concept for modeling and optimization of an engineering system to high-fidelity (fine) model accuracy ...
ISBN 978-0-471-33368-5. "Quantum Computational Software; Molecular Modeling; Visualization". www.q-chem.com. Retrieved 2020-01- ... "Advances in molecular quantum chemistry contained in the Q-Chem 4 program package". Molecular Physics. 113 (2): 184-215. doi: ... a molecular builder, and general visualization capabilities (MOs, densities, molecular vibrations, reaction pathways, etc.). ... by libwfa developed by Felix Plasser and co-workers Janus QM/MM interface YinYang Atom model without linked atoms ONIOM model ...
Korneev, K. V. (18 October 2019). "Mouse Models of Sepsis and Septic Shock". Molecular Biology. 53 (5): 704-717. doi:10.1134/ ... Immune cells not only recognise pathogen-associated molecular patterns but also damage-associated molecular patterns from ... The molecular character of this material was determined by Luderitz et al. in 1973. It was discovered in 1965 that a strain of ... The authors called for abandoning the use of mouse models in sepsis research; others rejected that but called for more caution ...
In QSAR modeling, the predictors consist of physico-chemical properties or theoretical molecular descriptors of chemicals; the ... Quantitative structure-activity relationship models (QSAR models) are regression or classification models used in the chemical ... Leach AR (2001). Molecular modelling: principles and applications. Englewood Cliffs, N.J: Prentice Hall. ISBN 978-0-582-38210-7 ... Like other regression models, QSAR regression models relate a set of "predictor" variables (X) to the potency of the response ...
By studying animal models and keeping in mind the innate differences in CYP3A4 activation, investigators can better predict ... Gonzalez FJ (2007). "CYP3A4 and pregnane X receptor humanized mice". Journal of Biochemical and Molecular Toxicology. 21 (4): ... Robertson GR, Field J, Goodwin B, Bierach S, Tran M, Lehnert A, Liddle C (July 2003). "Transgenic mouse models of human CYP3A4 ... In addition to providing an in vivo model, humanized CYP3A4 mice (hCYP3A4) have been used to further emphasize gender ...
2011 "Multiscale Modeling" 2010 "Regulation & Control in Biological Systems" 2009 "Molecular Evolution" 2008 "Computational ... ". "Multiscale Modeling". "Regulation and Control in Biological Systems". "Molecular Evolution". "Computational Structural ... 2021 [BC]2 Basel Computational Biology Conference 2019 [BC]2 Basel Computational Biology Conference "Big Data in Molecular ... " "BC2 Conference". "[BC]2 "Big Data in Molecular Medicine"". "13th [BC]2 Conference 2017". "12th [BC]2 Conference 2015 - ...
2. Palms on an oceanic island". Molecular Ecology. 16 (14): 2910-2921. doi:10.1111/j.1365-294x.2007.03304.x. PMID 17614906. ... Gavrilets, Sergei; Vose, Arron (2007). "Case studies and mathematical models of ecological speciation. ... Wallis, G.P.; Trewick, Steve A. (2009). "New Zealand phylogeography: evolution on a small continent". Molecular Ecology. 18 (17 ...
... (DAAO; also OXDA, DAMOX) is an enzyme with the function on a molecular level to oxidize D-amino acids to ... Olney JW, Newcomer JW, Farber NB (November 1999). "NMDA receptor hypofunction model of schizophrenia". Journal of Psychiatric ... Pilone MS (November 2000). "D-Amino acid oxidase: new findings". Cellular and Molecular Life Sciences. 57 (12): 1732-47. doi: ... September 2008). "Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and ...
Anon (2008). "A Special Issue in Honour of Professor Anthony J. Stone". Molecular Physics. 106 (12): 3. doi:10.1080/ ... Price, Sarah L. (1980). Model intermolecular pair potentials. ethos.bl.uk (PhD thesis). University of Cambridge. OCLC 557224619 ... Molecular Physics. 5 (5): 417-424. Bibcode:1962MolPh...5..417L. doi:10.1080/00268976200100471. ISSN 0026-8976. ...
"Quantum Computational Software; Molecular Modeling; Visualization". www.Q-Chem.com. Retrieved 2 January 2018. "Faculty Profile ... Molecular Physics, and Wires Computational Molecular Science. She has served as a guest editor for a special issue of J. Phys. ... Her Ph.D. research at the Fritz Haber Center focused on molecular dynamics in rare gas clusters and matrices. Upon completing ... In addition, she is an elected member of the International Academy of Quantum Molecular Science. In addition to her permanent ...
He later studied with Christopher A. Fields at New Mexico State University, gaining his PhD in molecular biology in 1992. From ... "Microbial gene identification using interpolated Markov models". Nucleic Acids Research. 26 (2): 544-8. doi:10.1093/nar/26.2. ... CS1 maint: discouraged parameter (link) "Recent Graduates , Molecular Biology". molb.research.nmsu.edu. Retrieved 15 September ...
Molecular Microbiology. 44 (6): 1575-87. doi:10.1046/j.1365-2958.2002.02978.x. PMID 12067345. SWISS-MODEL. Matched templates ... McDevitt CA, Hugenholtz P, Hanson GR, McEwan AG (June 2002). "Molecular analysis of dimethyl sulphide dehydrogenase from ... Model report Other data Dimethyl+sulfide:cytochrome+c2+reductase at the US National Library of Medicine Medical Subject ...
... and for the most typical models of relationships, Dk is close to 1, which means most of these models can be used to estimate ... Molecular Ecology. 9, 2056, 2015. ISSN 0962-1083 Legarra, Andres (2016). "Comparing estimates of genetic variance across ... However, different models may give different estimates of genetic variances. They found that expected genetic variances usually ... In this research, the researchers use the different relationship models to compare estimates of genetic variance components and ...
Locuson CW, Rock DA, Jones JP (June 2004). "Quantitative binding models for CYP2C9 based on benzbromarone analogues". ... Molecular Pharmacology. 68 (3): 644-51. doi:10.1124/mol.105.013763. PMC 1552103. PMID 15955872. ...
Troncale studied at the Catholic University of America from 1966 to 1970, and received his Ph.D. in 1970 in Molecular Biology. ... Systems Thinking and Dynamic Modeling Conference (June 25-27, 2000) Archived 2001-11-17 at archive.today. General info. ... Later in the 1970s he became Professor Cellular and Molecular Biology, and Director of the Institute for Advanced Systems ... Lenard Raphael Troncale (born 1943) is an American biologist, systems theorist, Professor Emeritus of Cellular and Molecular ...
Geyer MA, McIlwain KL, Paylor R (2002). "Mouse genetic models for prepulse inhibition: an early review". Molecular Psychiatry. ... Murine models are widely used to test hypotheses linking genetic components of various diseases with sensorimotor gating. While ... Dopamine, which plays a major role in schizophrenia, had been shown to regulate sensorimotor gating in rodent models. These ... Many animal studies of PPI are undertaken in order to understand and model the pathology of schizophrenia. Schizophrenia-like ...
Abbas A (2018). Cellular and molecular immunology. Elsevier. p. 447. ISBN 978-0-323-47978-3. Monroe EW, Daly AF, Shalhoub RF ( ... Andersen HH, Elberling J, Arendt-Nielsen L (September 2015). "Human surrogate models of histaminergic and non-histaminergic ... Haenisch B, Nöthen MM, Molderings GJ (November 2012). "Systemic mast cell activation disease: the role of molecular genetic ... Brady S (2012). Basic Neurochemistry - Principles of Molecular, Cellular and Medical Neurobiology. 225 Wyman Street, Waltham, ...
Molecular Ecology. 15 (2): 301. doi:10.1111/j.1365-294X.2006.02899.x. Dennis, C.; Wright, J. (2006). "Model Mentors". Nature. ... Butlin, R.; Rieseberg, L.; Smith., H. (2006). "Godfrey Hewitt - Recipient of 2005 Molecular Ecology Prize". Molecular Ecology. ... He was awarded the 2005 Molecular Ecology Prize, and he received a Lifetime Achievement Award for creative mentoring in science ... Butlin, R.; Rieseberg, L.; Smith., H. (2006). "Godfrey Hewitt - Recipient of 2005 Molecular Ecology Prize". ...
"Molecular modelling of the GABAA ion channel protein". Journal of Molecular Graphics & Modelling. 25 (5): 721-730. doi:10.1016/ ... Journal of Molecular Graphics and Modelling. 26 (4): 760-774. doi:10.1016/j.jmgm.2007.04.012. Miller PS, Aricescu AR (August ... Vijayan RS, Trivedi N, Roy SN, Bera I, Manoharan P, Payghan PV, Bhattacharyya D, Ghoshal N (November 2012). "Modeling the ... The ionotropic GABAA receptor protein complex is also the molecular target of the benzodiazepine class of tranquilizer drugs. ...
ISBN 978-0-9636769-4-8. Leach, Andrew R. (1996). Molecular Modelling. Harlow: Longman. pp. 83-85. ISBN 978-0-582-23933-3. ... Additionally, various important molecular properties calculated at MP3 and MP4 level are no better than their MP2 counterparts ... Helgaker, Trygve; Poul Jorgensen; Jeppe Olsen (2000). Molecular Electronic Structure Theory. Wiley. ISBN 978-0-471-96755-2. ... Pople, John A.; Binkley, J. Stephen; Seeger, Rolf (1976). "Theoretical models incorporating electron correlation". ...
Korneev, K. V. (18 October 2019). "Mouse Models of Sepsis and Septic Shock". Molecular Biology. 53 (5): 704-717. doi:10.1134/ ... Animal Testing Animal model BALB/c C57BL/6 Mouse models of colorectal and intestinal cancer Preclinical imaging Rat Park ... Information about mouse models from HOPES:Huntington's Disease Outreach Project for Education at Stanford Animal Model of ... They are widely considered to be the prime model of inherited human disease and share 99% of their genes with humans. With the ...
A tetrahedral model". Molecular Pharmacology. 28 (5): 391-9. PMID 2932631. Burt DR, Creese I, Snyder SH (April 1977). " ...
Kolafa, Jiří; Nezbeda, Ivo (May 1987). "Monte Carlo simulations on primitive models of water and methanol". Molecular Physics. ... Patchy particles are used as a shorthand for modelling anisotropic colloids, proteins and water and for designing approaches to ... Fusco, Diana; Charbonneau, Patrick (2013). "The crystallization of asymmetric patchy models for globular proteins in solution ... representation of the discontinous potential described above enables the simulation of patchy particles using molecular ...
In 2009, he joined Bar Ilan University as an associate professor at the Department of Chemistry leading the molecular modeling ... Molecular modelling, Computer-Aided Drug Design, and Chemoinformatics. Hanoch Senderowitz received his Ph.D. in 1993 from Tel ... "Molecular Dynamics Flexible Fitting Simulations Identify New Models of the Closed State of the Cystic Fibrosis Transmembrane ... Yosipof, Abraham; Senderowitz, Hanoch (2014). "Optimization of Molecular Representativeness". Journal of Chemical Information ...
Lamond AI, Spector DL (August 2003). "Nuclear speckles: a model for nuclear organelles". Review. Nature Reviews. Molecular Cell ... A second model proposes that proto-eukaryotic cells evolved from bacteria without an endosymbiotic stage. This model is based ... The first model known as the "syntrophic model" proposes that a symbiotic relationship between the archaea and bacteria created ... 2016). Molecular Cell Biology (Eighth ed.). New York: W.H. Freeman. ISBN 978-1-4641-8339-3. Alberts B, Johnson A, Lewis J, Raff ...
The first one is the one-ring embrace model, and the second one is the dimeric handcuff-model. The one-ring embrace model ... Haering CH, Löwe J, Hochwagen A, Nasmyth K (April 2002). "Molecular architecture of SMC proteins and the yeast cohesin complex ... Zhang N, Kuznetsov SG, Sharan SK, Li K, Rao PH, Pati D (December 2008). "A handcuff model for the cohesin complex". The Journal ... According to the handcuff model, each ring has one set of RAD21, SMC1, and SMC3 molecules. The handcuff is established when two ...
The Zucker rat was bred to be a genetic model for research on obesity and hypertension. They are named after Lois M. Zucker and ... August 1996). "Molecular cloning of rat leptin receptor isoform complementary DNAs--identification of a missense mutation in ... "Research Animal Models". CRiver.com. Charles River Laboratories. Archived from the original on 24 May 2013. Retrieved 5 August ... Like NOD mice, biobreeding rats are used as an animal model for Type 1 diabetes. The strain re-capitulates many of the features ...
It has a cage-like molecular structure, whose carbon skeleton can be viewed as three fused cyclohexane rings in the boat ... "Extensions in the use of plastic tetrahedral models". J. Chem. Educ. 42 (8): 408-412. doi:10.1021/ed042p408. CS1 maint: ... discouraged parameter (link) Hargittai, M.; Hargittai, I. (2013). "Polyhedral Molecular Geometries". In Senechal, M. (ed.). ...
If they are damaged, a molecular brake stops them from dividing until they are repaired. If they can't be repaired, they commit ... Cesare, Anthony J.; Reddel, Roger R. (2010). "Alternative lengthening of telomeres: Models, mechanisms and implications". ... Greenberg, RA (March 2005). "Telomeres, crisis and cancer". Current Molecular Medicine. 5 (2): 213-8. doi:10.2174/ ...
Liu, Dongyou (2017). Laboratory Models for Foodborne Infections. CRC Press. ISBN 9781498721684. Sails, Andrew (2014). Molecular ...
Single-neuron modeling[edit]. Main article: Biological neuron models. Even single neurons have complex biophysical ... We know from molecular biology that distinct parts of the nervous system release distinct chemical cues, from growth factors to ... Earlier models of memory are primarily based on the postulates of Hebbian learning. Biologically relevant models such as ... Lapicque introduced the integrate and fire model of the neuron in a seminal article published in 1907.[16] This model is still ...
Advances in the fields of molecular biology and genetics, as well as the use of animal models have been of great importance in ... "Human Molecular Genetics. 6 (10): 1647-56. doi:10.1093/hmg/6.10.1647. PMID 9300656.. ... Part A, Clinical and Molecular Teratology. 82 (2): 78-85. doi:10.1002/bdra.20426. PMID 18050313.. ... Mulliken JB, Gripp KW, Stolle CA, Steinberger D, Müller U (June 2004). "Molecular analysis of patients with synostotic frontal ...
Neuberger, M. S.; Honjo, T.; Alt, Frederick W. (2004). Molecular biology of B cells. Amsterdam: Elsevier. pp. 189-191. ISBN 0- ... B cells differentiate into plasma cells that produce antibody molecules closely modelled after the receptors of the precursor B ...
Sun T, Han X (2019). "Death versus dedifferentiation: The molecular bases of beta cell mass reduction in type 2 diabetes". ... "Projections of type 1 and type 2 diabetes burden in the U.S. population aged ,20 years through 2050: dynamic modeling of ... The Journal of Steroid Biochemistry and Molecular Biology. 114 (1-2): 40-3. doi:10.1016/j.jsbmb.2008.12.022. PMID 19444934.. ...
Molecular ageing in progeroid syndromes: Hutchinson-Gilford progeria syndrome as a model. Immun Ageing. 2009, 6: 4. PMC 2674425 ... Trends in molecular medicine. 2004, 9 (9): 370-5. PMID 13129702. doi:10.1016/S1471-4914(03)00162-X.. ...
"Journal of Molecular Biology. 354 (4): 789-800. doi:10.1016/j.jmb.2005.09.095. PMC 1403828. PMID 16277992.. ... 3D model (JSmol). *Interactive image. SMILES. *. CC(C)(C)NC(=O)[[email protected]@H]1CN(CCN1C[[email protected]](C[[email protected]@H](Cc2ccccc2)C(=O)N[[email protected]]3c4ccccc4C[[email protected] ...
... and an incorrect model of the anatomy and physiology of internal organs.[8][59][60][61][62][63] ... Trends in Molecular Medicine. 20 (9): 473-76. doi:10.1016/j.molmed.2014.06.007. PMID 25150944.. ... molecular biology, biophysics, and other natural sciences to clinical practice, using scientific methods to establish the ... Snyderman and Weil remarked that by the early twentieth century the Flexner model had helped to create the 20th-century ...
Due to scanty fossil evidence it is unclear which ape or apes contributed to the modern hominid clade, but molecular evidence ... and thus modern cycads are not a good model for a "living fossil".[17] ...
One possible way to achieve this, which has been successful in mouse models, is to use inhibitors of Ras activation in order to ... Nature Reviews Molecular Cell Biology. 10 (4): 276-86. doi:10.1038/nrm2654. PMID 19305417. MacDonald BT, Tamai K, He X (July ...
... which is a central premise of his model of selection in nature.[5] Later in his career, Castle would refine his model for ... Methods in Molecular Biology, Springer US, pp. 15-25, doi:10.1007/978-1-4939-9865-4_3, ISBN 9781493998654. , PMID 31541435. ... are based on a comparison of single QTL models with a model assuming no QTL. For instance in the "interval mapping" method[23] ... Methods in Molecular Biology, Springer US, 2072, pp. 15-25, doi:10.1007/978-1-4939-9865-4_3, ISBN 9781493998654. , PMID ...
Molecular properties can be modeled through sedimentation velocity analysis or sedimentation equilibrium analysis. During the ... it had exactly the same molecular weight.[11][12] How something of such a large molecular mass could be consistently found, ... Cao, W., Demeler B. Modeling Analytical Ultracentrifugation Experiments with an Adaptive Space-Time Finite Element Solution for ... Sedimentation Velocity Analysis of Heterogeneous Protein-Protein Interactions: Lamm Equation Modeling and Sedimentation ...
Resulting information can be used to build biological models, design experiments, or get up to speed in an area of research. ... The software has been cited in thousands of scientific molecular biology publications and is one of several tools for systems ... "Best of Show Award Winners Named at the Fifteenth International Molecular Medicine Tri-Conference" (Press release). Cambridge ... "Ingenuity Systems releases IPA™ 5.0 software, offering new biomarker and molecular toxicology capabilities" (PDF) (Press ...
1999). "Synthesis of multi-subunit domain gonadotropin complexes: a model for alpha/beta heterodimer formation". Biochemistry. ... Molecular function. • follicle-stimulating hormone activity. • ربط بروتيني. • فعالية الهرمون. Cellular component. • ...
Brioche T, Pagano AF, Py G, Chopard A (April 2016). "Muscle wasting and aging: Experimental models, fatty infiltrations, and ... cellular and molecular responses to depressed metabolism and low temperature". Physiol. Rev. 83 (4): 1153-81. doi:10.1152/ ... Brioche T, Pagano AF, Py G, Chopard A (April 2016). "Muscle wasting and aging: Experimental models, fatty infiltrations, and ...
... with terms containing particulate volumes and refractive indices replaced with terms for molecular polarizability.[8] ... Rayleigh sky model. *Ricean fading. *Optical phenomenon. *Dynamic light scattering. *Raman scattering ... can also be written in terms of individual molecules by expressing the dependence on refractive index in terms of the molecular ...
Função molecular. •extracellular matrix structural constituent. •protein binding. •extracellular matrix constituent conferring ... 2009). «Integrative predictive model of coronary artery calcification in atherosclerosis». Circulation. 120 (24): 2448-54. PMC ... Dyksterhuis LB, Weiss AS (2010). «Homology models for domains 21-23 of human tropoelastin shed light on lysine crosslinking». ... use of recombinantly expressed human elastin polypeptides as a model for investigations of structure and self-assembly of ...
... since more sophisticated models of the scanner Physics can be incorporated into the likelihood model than those used by ... 2003). "11C-metomidate PET imaging of adrenocortical cancer". European Journal of Nuclear Medicine and Molecular Imaging. 30 (3 ... Crump Institute for Molecular Imaging. Archived from the original (PDF) on May 18, 2015.. ... Vardi, Y.; L. A. Shepp; L. Kaufman (1985). "A statistical model for positron emission tomography". Journal of the American ...
Volkow ND, Koob GF, McLellan AT (January 2016). "Neurobiologic Advances from the Brain Disease Model of Addiction". N. Engl. J ... Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). New York: McGraw-Hill Medical. pp. 364-375. ISBN ... Thus, kindling has been suggested as a model for temporal lobe epilepsy in humans, where stimulation of a repetitive type ( ... Morimoto K, Fahnestock M, Racine RJ (2004). "Kindling and status epilepticus models of epilepsy: Rewiring the brain". Prog ...
Feugier, François (14 December 2006). Models of Vascular Pattern Formation in Leaves (PhD Thesis). University of Paris VI.. ... On the basis of molecular genetics, Eckardt and Baum (2010) concluded that "it is now generally accepted that compound leaves ... Read and Stokes (2006) consider two basic models, the "hydrostatic" and "I-beam leaf" form (see Fig 1).[40] Hydrostatic leaves ... "Modeling and Visualization of Leaf Venation Patterns". ACM SIGGRAPH 2005 Papers. 24 (3): 702-711. CiteSeerX 10.1.1.102.1926. ...
Disease models. Animal models and in particular non-human primates are being used to study different aspects of Ebola virus ... Klenk, Hans-Dieter; Feldmann, Heinz (2004). Ebola and Marburg viruses: molecular and cellular biology (Limited preview). ... Developments in organ-on-a-chip technology have led to a chip-based model for Ebola haemorrhagic syndrome.[262] ... Trends in Molecular Medicine. 12 (5): 206-15. doi:10.1016/j.molmed.2006.03.006. PMID 16616875.. ...
"Interaction model - Probing space weather with comets". KVI atomics physics. Archived from the original on 2006-02-13. ... "Rosetta finds molecular oxygen on comet 67P (Update)". phys.org. Retrieved 2017-01-08.. ...
Main articles: Mandala (political model), Greater India, and Indosphere. The Rajamandala (or Raja-mandala; circle of states) ... Hasegawa, Masami (2017). "Phylogeny mandalas for illustrating the Tree of Life". Molecular Phylogenetics and Evolution. 117: ... This mandala is generally structured according to the model of the universe as taught in a Buddhist classic text the Abhidharma ... but it originally meant to represent wholeness and a model for the organizational structure of life itself, a cosmic diagram ...
Molecular structureEdit. The 154 kb chloroplast DNA map of a model flowering plant (Arabidopsis thaliana: Brassicaceae) showing ... Alternative model of replicationEdit. One of the main competing models for cpDNA asserts that most cpDNA is linear and ... Leading model of cpDNA replicationEdit. Chloroplast DNA replication via multiple D loop mechanisms. Adapted from Krishnan NM, ... Alberts B (2002). Molecular biology of the cell (4. ed.). New York [u.a.]: Garland. ISBN 978-0-8153-4072-0. .. ...
"WHO Model List of Essential Medicines (19th List)" (PDF). World Health Organization. April 2015. Archived (PDF) from the ... Seyfizadeh, Narges; Seyfizadeh, Nayer; Hasenkamp, J; Huerta-Yepez, S (2016). "A molecular perspective on rituximab: A ...
"Molecular Reproduction, Development and Genetics at IISc". www.mrdg.iisc.ernet.in.. ... "A Small Animal Model of ETEC-Mediated Diarrhea - Grand Challenges". gcgh.grandchallenges.org.. ... She is currently the Chairperson of the Department of Molecular Reproduction, Development and Genetics[1] and the Co-chair of ... In 1993, she was appointed as Assistant Professor at the Department of Molecular Reproduction, Development and Genetics,[12] ...
Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions ...
They have combined molecular and genetic approaches to answer some of Darwins key questions about the natural variation of ... developing models for the evolution of genetic systems, including sex and recombination, inbreeding and outbreeding, separate ... Distinguished for his work on molecular evolution, in particular on the role of stochastic events in determining the rate of ...
Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions ...
"Molecular Biology of the Cell. 6 (5): 509-24. doi:10.1091/mbc.6.5.509. PMC 301212 . PMID 7545030.. ... American Journal of Respiratory Cell and Molecular Biology. 24 (2): 101-7. doi:10.1165/ajrcmb.24.2.4264. PMID 11159042.. ... Spacefilling model of substance P. Identifiers. Symbol. TAC1. Alt. symbols. TAC2, NKNA. ...
Russo J, Russo I (1987). "Biological and molecular bases of mammary carcinogenesis". Laboratory Investigation 57 (2): 112-37. ... but the parallelism between the DMBA-induced rat mammary carcinoma model and the human situation is striking. …Abortion would ...