Bioluminescence
It suggests that the original purpose of luciferases was as mixed-function oxygenases. As the early ancestors of many species ... Bioluminescence has several functions in different taxa. Steven Haddock et al. (2010) list as more or less definite functions ... The main function of this is to alert the fish to the presence of its prey. The additional pigment is thought to be assimilated ... The following functions are reasonably well established in the named organisms. In many animals of the deep sea, including ...
Oxygenase
... or mixed function oxidase, transfer one oxygen atom to the substrate, and reduce the other oxygen atom to water. Dioxygenases, ... The oxygenases form a class of oxidoreductases; their EC number is EC 1.13 or EC 1.14. Most oxygenases contain either a metal, ... Oxygenases constitute a major intracellular source of iron and carbon monoxide Two types of oxygenases are recognized: ... An oxygenase is any enzyme that oxidizes a substrate by transferring the oxygen from molecular oxygen O2 (as in air) to it. ...
Lysine 2-monooxygenase
... internal monooxygenases o internal mixed-function oxidases). The systematic name of this enzyme class is L-lysine:oxygen 2- ... Takeda H, Hayaishi O (1966). "Crystalline L-lysine oxygenase". J. Biol. Chem. 241 (11): 2733-6. PMID 5911646. Takeda H, ... oxygenases). The oxygen incorporated need not be derived from O with incorporation of one atom of oxygen ( ... oxidoreductase (decarboxylating). Other names in common use include lysine oxygenase, lysine monooxygenase, and L-lysine-2- ...
Arginine 2-monooxygenase
... internal monooxygenases o internal mixed-function oxidases). The systematic name of this enzyme class is L-arginine:oxygen 2- ... Olomucki A, Pho DB, Lebar R, Delcambe L, Thoai NV (1968). "[Arginine oxygenase (decarboxylating). V. Purification and flavin ... oxygenases). The oxygen incorporated need not be derived from O with incorporation of one atom of oxygen ( ... arginine oxygenase (decarboxylating), and arginine decarboxy-oxidase. This enzyme participates in urea cycle and metabolism of ...
Joanna Wilson
Measuring the potency of pulp mill effluents for induction of hepatic mixed-function oxygenase activity in fish. Journal of ...
Alkylglycerol monooxygenase
... is a membrane-bound mixed-function oxidase and harbours a fatty acid hydroxylase motif. The iron is ... Other names in use are glyceryl-ether monooxygenase, glyceryl-ether cleaving enzyme, glyceryl ether oxygenase, glyceryl ...
Oplophorus-luciferin 2-monooxygenase
... internal monooxygenases o internal mixed-function oxidases). Although the enzyme is part of the group of enzymes that act on ... oxygenases). The oxygen incorporated need not be derived from O with incorporation of one atom of oxygen ( ... however its exact function is not known [3,4,7]. Although originally thought to have the exact same mechanism as the Renilla ... but functions ineffectively without its larger, subunit counterpart [3,4]. Although the crystal structure of OpLec has yet to ...
Lactate 2-monooxygenase
... internal monooxygenases o internal mixed-function oxidases). The systematic name of this enzyme class is (S)-lactate:oxygen 2- ... lactic oxygenase, lactate oxygenase, lactic oxidase, L-lactate monooxygenase, lactate monooxygenase, and L-lactate-2- ... oxygenases). The oxygen incorporated need not be derived from O with incorporation of one atom of oxygen ( ...
Cypridina-luciferin 2-monooxygenase
Tryptophan 2-monooxygenase
Phenylalanine 2-monooxygenase
Apo-beta-carotenoid-14',13'-dioxygenase
Watasenia-luciferin 2-monooxygenase
Camphor 1,2-monooxygenase
Conrad HE, Dubus R, Namtvedt MJ, Gunslaus IC (1965). "Mixed Function Oxidation. II. Separation and Properties of the Enzymes ... oxygenase, camphor 1,2-mono, and ketolactonase I. It employs one cofactor, iron. ... Trudgill PW, DuBus R, Gunsalus IC (1966). "Mixed function oxidation. VI. Purification of a tightly coupled electron transport ...
Methanol
These enzymes are mixed-function oxygenases, i.e. oxygenation is coupled with production of water and NAD+: CH4 + O2 + NADPH + ... Similarly, the alcohol can be gelled to reduce risk of leaking or spilling, as with the brand "Sterno". Methanol is mixed with ...
List of MeSH codes (D08)
Mixed-function oxidase
Mixed+Function+Oxygenases at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Moskwa PS, Vadi H, and ... Mixed-function oxidase is the name of a family of oxidase enzymes that catalyze a reaction in which each of the two atoms of ... The mixed-function oxidase reaction proceeds as follows: AH + BH2 + O2 --> AOH + B + H2O (H2O as catalyst.) High levels of ... The name "mixed-function oxidase" indicates that the enzyme oxidizes two different substrate simultaneously. Desaturation of ...
Methacrylonitrile
It has been shown that treatment of mice with carbon tetrachloride, which acts on the mixed function oxygenase system, results ...
Dinoflagellate luciferase
... internal monooxygenases or internal mixed-function oxidases). Dinoflagellate luciferase is a single protein with three ... oxygenases) that are not necessarily derived from O2, with incorporation of one atom of oxygen ( ...
Cytochrome P450 reductase
... impact on plasma cholesterol homeostasis and the function and regulation of microsomal cytochrome P450 and heme oxygenase". The ... who dissected the P450-containing mixed function oxidase system into three constituent components: POR, cytochrome P450, and ... The reduction of cytochrome P450 is not the only physiological function of POR. The final step of heme oxidation by mammalian ... Pandey AV, Flück CE (May 2013). "NADPH P450 oxidoreductase: structure, function, and pathology of diseases". Pharmacology & ...
Catechol 1,2-dioxygenase
The function of this hydrophobic tunnel is unknown, though two hypotheses have been postulated concerning its utility. The ... Hayaishi O, Lardy H, Myrbäck K (1963). "Direct oxygenation by O2, oxygenases". In Boyer PD (ed.). The Enzymes. Vol. 8 (2nd ed ... Each catalytic domain is composed of two stacked, mixed topology β sheets and several random coils. These sheets and coils ... Hayaishi S, Katagiri M, Rothberg S (1957). "Pioneering the Field of Oxygenases through the Study of Tryptophan Metabolism: the ...
Oxylipin
Both groups were given Vitamin C (ascorbyl palmitate) and Vitamin E (mixed tocopherol) supplements. Wasternack C (2007). " ... to modify adipocyte formation and function. Most oxylipins in the body are derived from linoleic acid or alpha-linolenic acid. ... heme-dependent fatty acid oxygenases (plants, fungi), and cyclooxygenases (animals). Fatty acid hydroperoxides or endoperoxides ...
Phosphoribulokinase
Its main function is to regenerate RuBP, which is the initial substrate and CO2-acceptor molecule of the Calvin Cycle. PRK ... In Rhodobacter sphaeroides, PRK (or RsPRK) exists as a homooctomer with protomers composed of seven-stranded mixed β-sheets, ... Along with ribulose 1,5-bisphosphate carboxylase/oxygenase (RuBisCo), phosphoribulokinase is unique to the Calvin Cycle. ... Miziorko HM (2000). "Phosphoribulokinase: Current Perspectives on the Structure/Function Basis for Regulation and Catalysis". ...
Bacterial cell structure
In addition to these functions, prokaryotic membranes also function in energy conservation as the location about which a proton ... Deep lakes that experience winter mixing expose the cells to the hydrostatic pressure generated by the full water column. This ... especially ribulose bisphosphate carboxylase/oxygenase, RuBisCO, and carbonic anhydrase). It is thought that the high local ... Fimbriae usually function to facilitate the attachment of a bacterium to a surface (e.g. to form a biofilm) or to other cells ( ...
Bradykinin receptor B2
Binding of an inhibitory peptide to the oxygenase domain blocks uncoupled NADPH oxidation". J. Biol. Chem. 275 (8): 5291-6. doi ... 1993). "Cloned murine bradykinin receptor exhibits a mixed B1 and B2 pharmacological selectivity". Mol. Pharmacol. 44 (2): 346- ... motif in the first extracellular loop with other human G-protein coupled receptors implications for HIV-1 coreceptor function ...
Iron in biology
Once iron enters the ocean, it can be distributed throughout the water column through ocean mixing and through recycling on the ... ISBN 0-935702-73-3. Kikuchi, G.; Yoshida, T.; Noguchi, M. (2005). "Heme oxygenase and heme degradation". Biochemical and ... Neilands, J.B. (1995). "Siderophores: structure and function of microbial iron transport compounds". The Journal of Biological ... but there the major effect is by far its interference with the proper functioning of the electron transport protein cytochrome ...
Sulfur
"The Function of Biotin". www.chem.uwec.edu. Retrieved 10 June 2022. Edwards, Katie A. "Thiamine Biochemistry". thiamine.dnr. ... Elemental sulfur (ES) is sometimes mixed with bentonite to amend depleted soils for crops with high requirement in organo- ... They depend on enzymes such as sulfur oxygenase and sulfite oxidase to oxidize sulfur to sulfate. Some lithotrophs can even use ... Sulfur is one of the core chemical elements needed for biochemical functioning and is an elemental macronutrient for all living ...
Vitamin A
Each subtype has functions driven by the types of cytokines secreted and organs to which the cells preferentially migrate, also ... For malaria, clinical trial results are mixed, either showing that vitamin A treatment did not reduce the incidence of probable ... oxygenase 2 in carotenoid metabolism and diseases". Exp Biol Med (Maywood). 241 (17): 1879-87. doi:10.1177/1535370216657900. ... It functions as a retinoic acid receptor (RAR)-γ agonist. Non-prescription topical products that have health claims for ...
Sulfurimonas
However, as shown below, not all species can use each of the mentioned electron donors (Table 2). Sulfur Oxygenase Reductase ( ... This enriched layer moves down and mixes with underlying sediment. Oxygen that is taken from the water penetrates this ... The researchers found that Type VI SQR functioning in high sulfide environments, and hypothesized that S. 'denitrificans ... Janosch, Claudia (2015). "Sulfur Oxygenase Reductase (Sor) in the Moderately Thermoacidophilic Leaching Bacteria: Studies in ...
Opioid
Sydenham's 1669 recipe for laudanum mixed opium with wine, saffron, clove and cinnamon. Sydenham's laudanum was used widely in ... Brennan MJ (March 2013). "The effect of opioid therapy on endocrine function". The American Journal of Medicine. 126 (3 Suppl 1 ... It also decreases cyclo-oxygenase activity. It has recently been discovered that most or all of the therapeutic efficacy of ... Patients with chronic pain using opioids had small improvements in pain and physically functioning and increased risk of ...