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*  Protein kinase, AMP-activated, alpha 1
"Stimulation of glucose transport by AMP-activated protein kinase via activation of p38 mitogen-activated protein kinase". J. ... 1996). "Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the ... Bolster DR, Crozier SJ, Kimball SR, Jefferson LS (2002). "AMP-activated protein kinase suppresses protein synthesis in rat ... AMP-activated protein kinase catalytic subunit alpha-1 is an enzyme that in humans is encoded by the PRKAA1 gene. The protein ...
*  MAPK3
Mitogen-activated protein kinase 3 is an enzyme that in humans is encoded by the MAPK3 gene. The protein encoded by this gene ... "Entrez Gene: MAPK3 mitogen-activated protein kinase 3". Buggele WA, Johnson KE, Horvath CM (2012). "Influenza A virus infection ... Meloche S, Pouysségur J (2007). "The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S- ... "The mitogen-activated protein kinase phosphatase-3 N-terminal noncatalytic region is responsible for tight substrate binding ...
*  PLCB2
Barr AJ, Marjoram R, Xu J, Snyderman R (2002). "Phospholipase C-beta 2 interacts with mitogen-activated protein kinase kinase 3 ... "Phospholipase C-beta 2 interacts with mitogen-activated protein kinase kinase 3". Biochem. Biophys. Res. Commun. 293 (1): 647- ... Buhl AM, Osawa S, Johnson GL (1995). "Mitogen-activated protein kinase activation requires two signal inputs from the human ... This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11, as well as G-beta gamma subunits. PLCB2 has been ...
*  MicroRNA
... -21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase- ... binding protein], PACT (protein activator of the interferon-induced protein kinase), the SMN complex, fragile X mental ... HMGA proteins (HMGA1a, HMGA1b and HMGA2) are implicated in cancer, and expression of these proteins is regulated by microRNAs. ... HMGA2 protein specifically targets the promoter of ERCC1, thus reducing expression of this DNA repair gene. ERCC1 protein ...
*  MAP2K3
"Human mitogen-activated protein kinase kinase kinase mediates the stress-induced activation of mitogen-activated protein kinase ... the protein kinase TAO2 and identification of its mitogen-activated protein kinase/extracellular signal-regulated kinase kinase ... The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase ... "Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated ...
*  DUSP6
... a novel cytosolic protein-tyrosine phosphatase that exemplifies a new class of mitogen-activated protein kinase phosphatase". ... a novel cytosolic protein-tyrosine phosphatase that exemplifies a new class of mitogen-activated protein kinase phosphatase". ... "Extracellular signal-regulated kinases phosphorylate mitogen-activated protein kinase phosphatase 3/DUSP6 at serines 159 and ... Saha M, Skopelja S, Martinez E, Alvarez DL, Liponis BS, Romero-Sandoval EA (Oct 2013). "Spinal mitogen-activated protein kinase ...
*  GATA2
"Regulation of GATA-2 phosphorylation by mitogen-activated protein kinase and interleukin-3". J. Biol. Chem. 270 (8): 4101-7. ... GATA2 is a human gene which makes a protein called GATA binding protein 2 - a transcription factor. The GATA family of ... complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1". Proc. Natl. Acad. Sci. U.S.A. 92 (21): 9585-9. ... complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1". Proc. Natl. Acad. Sci. U.S.A. 92 (21): 9585-9. ...
*  Betacellulin
"Betacellulin induces angiogenesis through activation of mitogen-activated protein kinase and phosphatidylinositol 3'-kinase in ... Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. Betacellulin is ... This protein is a ligand for the EGF receptor. BTC is a polymer of about 62-111 amino acid residues. Secondary Structure: 6% ... The structure for the small protein Betacellulin that is shown was determined by two-dimensional nuclear magnetic resonance ...
*  Mothers against decapentaplegic homolog 7
... cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3 ... Erk-family MAP kinases, the Ca2+ /calmodulin-dependent protein kinase II (CamKII) and protein kinase C (PKC). Smad7 does not ... contains important regulatory peptide motifs including potential phosphorylation sites for mitogen-activated protein kinases( ... Yakymovych I, Ten Dijke P, Heldin CH, Souchelnytskyi S (March 2001). "Regulation of Smad signaling by protein kinase C". FASEB ...
*  MAP4K3
This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates ... Mitogen-activated protein kinase kinase kinase kinase 3 is a protein that in humans is encoded by the MAP4K3 gene. ... Mitogen-activated protein kinase kinase kinase kinase 3". Retrieved 2017-09-22. Lam D, Dickens D, Reid EB, Loh SH, Moisoi N, ... "The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells". Nat. Immunol. 12 (11): ...
*  Vascular endothelial growth inhibitor
Involvement of activation of stress protein kinases (stress-activated protein kinase and p38 mitogen-activated protein kinase) ... a new member of the TNF family activates nuclear factor-kappa B and c-Jun N-terminal kinase and modulates cell growth". ... is protein that in humans is encoded by the TNFSF15 gene. VEGI is an anti-angiogenic protein. It belongs to tumor necrosis ... The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is ...
*  DHRS7B
... and on the positive strand is the gene Mitogen-activated protein kinase, kinase 3 (MAP2K3). Microarray and EST data indicates ... "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi:10.1016/j.cell ... Other proteins interacting with DHRS7B have only been identified through text-mining. Conservation of the DHRS7B protein ... DHRS7B encodes a protein that is predicted to function in steroid hormone regulation. A deletion in the chromosomal region ...
*  HSF1
"Sequential phosphorylation by mitogen-activated protein kinase and glycogen synthase kinase 3 represses transcriptional ... a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase ... The genes activated by HSF1 under heat shock conditions have been recently shown to differ from those activated in malignant ... transcription factor 1 binds selectively in vitro to Ku protein and the catalytic subunit of the DNA-dependent protein kinase ...
*  MAP3K3
... and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase ... Mitogen-activated protein kinase kinase kinase 3 is an enzyme that in humans is encoded by the MAP3K3 gene, which is located on ... "Entrez Gene: MAP3K3 mitogen-activated protein kinase kinase kinase 3". Gilmore PM, McCabe N, Quinn JE, Kennedy RD, Gorski JJ, ... "BRCA1 interacts with and is required for paclitaxel-induced activation of mitogen-activated protein kinase kinase kinase 3". ...
*  FGFR1OP
... translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR ... The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic ... This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) ... Yan X, Habedanck R, Nigg EA (2006). "A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule ...
*  Lipoteichoic acid
Its activation also induces mitogen-activated protein kinases (MAPK) activation along with Phosphoinositide 3-kinase activation ...
*  MAP3K7IP3
Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 is an enzyme that in humans is encoded by the MAP3K7IP3 ... "Entrez Gene: MAP3K7IP3 mitogen-activated protein kinase kinase kinase 7 interacting protein 3". Bouwmeester T, Bauch A, Ruffner ... and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 ... Cheung PC, Nebreda AR, Cohen P (Feb 2004). "TAB3, a new binding partner of the protein kinase TAK1". Biochem J. 378 (Pt 1): 27- ...
*  MAPK phosphatase
"Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete ... Wu, J. J.; Zhang, L.; Bennett, A. M. (16 May 2005). "The Noncatalytic Amino Terminus of Mitogen-Activated Protein Kinase ... Wu, J. J.; Zhang, L.; Bennett, A. M. (16 May 2005). "The Noncatalytic Amino Terminus of Mitogen-Activated Protein Kinase ... Wu, J. J.; Zhang, L.; Bennett, A. M. (16 May 2005). "The Noncatalytic Amino Terminus of Mitogen-Activated Protein Kinase ...
*  SPRED3
... family of proteins that regulate growth factor-induced activation of the MAP kinase cascade. GRCh38: Ensembl release 89: ... Sprouty-related, EVH1 domain-containing protein 3 also known as Spread-3 is a protein that in humans is encoded by the SPRED3 ... kinase activation in hematopoietic cells". The Journal of Biological Chemistry. 279 (50): 52543-51. doi:10.1074/jbc.M405189200 ... Spread-3 is a member of the Sprouty (see SPRY1/SPRED) ... "Eve-3: a liver enriched suppressor of Ras/MAPK signaling". ...
*  SPRED1
The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. ... Spread-1 is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth ... Sprouty-related, EVH1 domain-containing protein 1 (Spread-1) is a protein that in humans is encoded by the SPRED1 gene located ... This mutation may result in a truncated nonfunctional protein. Blast cells analysis displayed the same abnormality as germline ...
*  HER2/neu
Signaling pathways activated by HER2 include: mitogen-activated protein kinase (MAPK) phosphoinositide 3-kinase (PI3K/Akt) ... "Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation ... Receptor tyrosine-protein kinase erbB-2, also known as CD340 (cluster of differentiation 340), proto-oncogene Neu, Erbb2 ( ... phospholipase C γ protein kinase C (PKC) Signal transducer and activator of transcription (STAT) In summary, signaling through ...
*  Mitogen-activated protein kinase
Signal transduction MAP kinase kinase MAP kinase kinase kinase MAP kinase kinase kinase kinase MAPK1 (ERK2) MAPK3 (ERK1) MAPK7 ... MAP Kinase Resource . Table of names for mitogen-activated kinases. MAPK cascade picture Mitogen-Activated Protein Kinases at ... A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of protein kinase that is specific to the amino acids serine ... The closest relatives of MAPKs are the cyclin-dependent kinases (CDKs). The first mitogen-activated protein kinase to be ...
*  Mitogen-activated protein kinase 9
... is an enzyme that in humans is encoded by the MAPK9 gene. The protein encoded by this gene ... a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase ... virus type 1 and its coat protein gp120 induce apoptosis and activate JNK and ERK mitogen-activated protein kinases in human ... "The JIP group of mitogen-activated protein kinase scaffold proteins". Molecular and Cellular Biology. 19 (10): 7245-54. doi: ...
*  PIK3C2G
... kinase and mitogen-activated protein (MAP) kinase pathways". J. Leukoc. Biol. 78 (4): 1016-23. doi:10.1189/jlb.0105056. PMID ... and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain ... "Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and - ... 1998). "Extracellular HIV-1 Tat protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat ...
*  Granulocyte colony-stimulating factor
... and Ras/mitogen-activated protein kinase (MAPK) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signal ... The natural human glycoprotein exists in two forms, a 174- and 177-amino-acid-long protein of molecular weight 19,600 grams per ... Loop mobility in a four-helix-bundle protein". Biochemistry. 33 (28): 8453-63. doi:10.1021/bi00194a009. PMID 7518249. Corcione ... G-CSF regulates them using Janus kinase (JAK)/signal transducer and activator of transcription (STAT) ...
*  MAPK8IP3
"Entrez Gene: MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3". Matsuura, Hiroshi; Nishitoh Hideki; Takeda ... "Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3". Mol Cell Biol. 20 (3): 1030 ... MAPK8IP3 has been shown to interact with ASK1, C-Raf, PTK2, MAPK10, Mitogen-activated protein kinase 9, MAPK8, MAP2K1, KLC2, ... 2002). "A scaffold protein in the c-Jun N-terminal kinase signaling pathway is associated with focal adhesion kinase and ...
*  CXCR3
Other names for CXCR3 are G protein-coupled receptor 9 (GPR9) and CD183. There are three isoforms of CXCR3 in humans: CXCR3-A, ... CXCR3 is expressed primarily on activated T lymphocytes and NK cells, and some epithelial cells. CXCR3 and CCR5 are ... Binding of CXCL9, CXCL10, and CXCL11 to CXCR3 is able to elicit increases in intracellular Ca2++ levels and activate ... Chemokine receptor CXCR3 is a Gαi protein-coupled receptor in the CXC chemokine receptor family. ...