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*  Inner mitochondrial membrane
The inner mitochondrial membrane (IMM) is the mitochondrial membrane which separates the mitochondrial matrix from the ... In the inner mitochondrial membrane, the protein-to-lipid ratio is 80:20, in contrast to the outer membrane, which is 50:50. ... The inner mitochondrial membrane is both an electrical insulator and chemical barrier. Sophisticated ion transporters exist to ... In pig heart mitochondria, phosphatidylethanolamine makes up the majority of the inner mitochondrial membrane at 37.0% of the ...
*  Mitochondrial membrane transport protein
Mitochondrial carrier Membrane transport protein Mitochondrial Membrane Transport Proteins at the US National Library of ... Mitochondrial membrane transport proteins are proteins which exist in the membranes of mitochondria and which serve to ... Examples of mitochondrial transport proteins include the following: The mitochondrial permeability transition pore, which opens ... The mitochondrial permeability transition pore and its role in cell death. Biochemical Journal. Volume 341, Pages 233-249. PMID ...
*  Crista
Three models proposed were: Baffle model - According to Palade, the mitochondrial inner membrane is convoluted in a baffle-like ... Griparic, L; van der Bliek, AM (April 2001). "The many shapes of mitochondrial membranes". Traffic (Copenhagen, Denmark). 2 (4 ... With the discovery of the dual-membrane nature of mitochondria, the pioneers of mitochondrial ultrastructural research proposed ... across the inner mitochondrial membrane known as the proton-motive force. As a result, chemiosmosis occurs, and the enzyme ATP ...
*  ATP10 protein
ATP10 is associated with the mitochondrial membrane. It is suggested that the ATP10 product is not a subunit of the ATPase ... It is essential for the assembly of the mitochondrial F1-F0 complex. A yeast nuclear gene (ATP10) encodes a product that is ... Ackerman SH, Tzagoloff A (June 1990). "ATP10, a yeast nuclear gene required for the assembly of the mitochondrial F1-F0 complex ... Mutations in ATP10 induce a loss of rutamycin sensitivity in the mitochondrial ATPase, but do not affect the respiratory ...
*  Porin (protein)
"Porins from Mitochondrial and Bacterial Outer Membranes: Structural and Functional Aspects". Anion Carriers of Mitochondrial ... In gram-negative bacteria, the inner membrane is the major permeability barrier. The outer membrane is more permeable to ... The Mitochondrial and Plastid Porin (MPP) Family 1.B.9 - The FadL Outer Membrane Protein (FadL) Family 1.B.10 - The Nucleoside- ... The Peroxysomal Membrane Porin 4 (PxMP4) Family 3.A.8 - The Mitochondrial Protein Translocase (MPT) Family 1.B.34 - The ...
*  TXN2
Involvement in mitochondrial membrane potential and cell death". The Journal of Biological Chemistry. 277 (36): 33249-57. doi: ... Involvement in mitochondrial membrane potential and cell death". The Journal of Biological Chemistry. 277 (36): 33249-57. doi: ... It may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced ... The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection ...
*  Deborah Doniach
"Mitochondrial antibodies in primary biliary cirrhosis. I. Localization of the antigen to mitochondrial membranes". The Journal ...
*  Carnitine palmitoyltransferase I
CPT1 is an integral membrane protein that associates with the mitochondrial outer membrane through transmembrane regions in the ... on the outer mitochondrial membrane, the activated fatty acids must be oxidized within the mitochondrial matrix. Long chain ... CPT1 is associated with the outer mitochondrial membrane. This enzyme can be inhibited by malonyl CoA, the first committed ... A translocase then shuttles the acyl carnitine across the inner mitochondrial membrane where it is converted back into ...
*  PARL
... mitochondrial also known as mitochondrial intramembrane cleaving protease PARL is an inner mitochondrial membrane protein that ... OPA1 mainly regulates mitochondrial fusion in the mitochondrial inner membrane, but after proteolytic cleavage by PARL, its ... This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide ... McQuibban GA, Saurya S, Freeman M (May 2003). "Mitochondrial membrane remodelling regulated by a conserved rhomboid protease". ...
*  IMMP2L
Inner mitochondrial membrane peptidase subunit 2 (IMMP2L) is an enzyme that in humans is encoded by the IMMP2L gene on ... The gene IMMP2L encodes protein Inner mitochondrial membrane peptidase subunit 2 in human. The human IMMP2L gene has 18 exons ... The human protein Inner mitochondrial membrane peptidase subunit 2 has two isoforms due to alternative splicing. One isoform is ... "Entrez Gene: IMMP2L Inner mitochondrial membrane peptidase subunit 2". "Q96T52 - IMP2L_HUMAN". Uniprot. Kozlowski, LP (21 ...
*  Apo2.7
... is a protein confined to the mitochondrial membrane. It can be detected during early stages of apoptosis. It can be used ...
*  8-Anilinonaphthalene-1-sulfonic acid
Its permeability to mitochondrial membranes makes it particularly useful. Andras Malnasi-Csizmadia; György Hegyi; Ferenc ... of double-reciprocal plots in the derivation of binding parameters for fluorescent probes binding to mitochondrial membranes". ...
*  Rhodamine 123
"Mitochondrial membrane potential in living cells."Annu Rev Cell Biol. 4 (1988) 155-181 M. Huang, A. K. S. Camara, D. F. Stowe, ... "Mitochondrial inner membrane electrophysiology assessed by rhodamine-123 transport and fluorescence" Annals of Biomedical ... This use relies on the fact that rhodamine 123 accumulates in membranes in a manner which is dependent on membrane polarization ... Rhodamine fluorescence can also be used as a measure of membrane polarization in live cell assays both within mitochondria and ...
*  Intrinsic apoptosis
Kroemer, G., Galluzzi, L., and Brenner, C. (2007). Mitochondrial membrane permeabilization in cell death. Physiol Rev 87, 99- ... The caspases can be activated through either the intrinsic (mitochondrial mediated) or extrinsic (death receptor mediated) ...
*  SLC25A6
Deniaud A, Brenner C, Kroemer G (2004). "Mitochondrial membrane permeabilization by HIV-1 Vpr". Mitochondrion. 4 (2-3): 223-33 ... 2002). "The human mitochondrial ADP/ATP carriers: kinetic properties and biogenesis of wild-type and mutant proteins in the ... 2002). "Close location of the first loop to the third loop of the mitochondrial ADP/ATP carrier deduced from cross-linking ... Jang JY, Lee CE (2003). "Mitochondrial adenine nucleotide translocator 3 is regulated by IL-4 and IFN-gamma via STAT-dependent ...
*  NUPL2
Deniaud A, Brenner C, Kroemer G (2005). "Mitochondrial membrane permeabilization by HIV-1 Vpr". Mitochondrion. 4 (2-3): 223-233 ...
*  Israel Hanukoglu
These proteins are located on the inner mitochondrial membrane. Israel reconstituted this system using proteins he purified, ... Yet, in the eccrine sweat glands, ENaC was localized on the apical cell membrane exposed to the duct of these sweat glands. ... Implications for membrane organization and gene regulation". European Journal of Biochemistry. 157 (1): 27-31. doi:10.1111/j. ... During his Ph.D. thesis research, Israel isolated the mitochondrial enzymes that catalyze the first step in the synthesis of ...
*  Phosphatidylglycerophosphatase
Cardiolipin is a unique dimeric phosphoglycerolipid predominantly present in mitochondrial membranes. The inverted phosphatase ... This is a family of proteins that acts as a mitochondrial phosphatase in cardiolipin biosynthesis. ... Osman, Christof; Haag, Mathias; Wieland, Felix T; Brügger, Britta; Langer, Thomas (2010). "A mitochondrial phosphatase required ...
*  Late embryogenesis abundant proteins
Tolleter D, Hincha DK, Macherel D (2010). "A mitochondrial late embryogenesis abundant protein stabilizes model membranes in ... LEA proteins are particularly protective of mitochondrial membranes against dehydration damage. Cryptobiosis Antifreeze ... conformational changes in transcription factors or integral membrane proteins due to water loss have been suggested. ...
*  Voltage-dependent anion channel
Benz R (1994). "Permeation of hydrophilic solutes through mitochondrial outer membranes: review on mitochondrial porins". ... Voltage-dependent anion channels are a class of porin ion channel located on the outer mitochondrial membrane. There is debate ... This protein contains about 280 amino acids and forms a beta barrel which spans the mitochondrial outer membrane. Since its ... This major protein of the outer mitochondrial membrane of eukaryotes forms a voltage-dependent anion-selective channel (VDAC) ...
*  Choline transporter
They are also found on the mitochondrial membrane. CTL2 was found to be highly expressed on the mitochondria. Meanwhile, CTL1 ... Moreover, it was found that the choline uptake is also influenced by the electronegativity of the plasma membrane. When the ... The choline absorption decreases majorly as a result of the membrane depolarization by the potassium ions. The choline uptake ... It is a cell membrane transporter and carries choline into acetylcholine-synthesizing neurons. Hemicholinium-3 is an inhibitor ...
*  Ion channel hypothesis of Alzheimer's disease
Aβ injection in rats has been shown to damage mitochondrial structure in neurons, decrease mitochondrial membrane potential, ... generation of mitochondrial reactive oxygen species (ROS), rupture of the outer mitochondrial membrane, and release of ... Ca2+ influx into mitochondria can collapse mitochondrial membrane potential, causing MPTP opening, which then induces ... Aβ channels may also trigger apoptosis through insertion in mitochondrial membranes. ...
*  Glyceraldehyde 3-phosphate dehydrogenase
VDAC1 to induce mitochondrial membrane permeabilization (MMP) and apoptosis; Inositol 1,4,5-trisphosphate receptor to regulate ... a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization". Oncogene. 26 (18): 2606-20. doi:10.1038/sj.onc ... Recent studies have also revealed that GAPDH is expressed in an iron dependent fashion on the exterior of the cell membrane a ... In red blood cells, GAPDH and several other glycolytic enzymes assemble in complexes on the inside of the cell membrane. The ...
*  Rhomboid protease
In Drosophila, the mitochondrial rhomboid also regulates mitochondrial membrane fusion. In mammals too, mitochondrial function ... In yeast this has been shown to control mitochondrial function and morphology by regulating membrane fusion via the cleavage of ... McQuibban, G. A.; Saurya, S.; Freeman, M. (2003). "Mitochondrial membrane remodelling regulated by a conserved rhomboid ... What is unique about intramembrane proteases is that their active sites are buried in the lipid bilayer of cell membranes, and ...
*  Lithocholic acid
The bile acid accumulates in the inner and outer mitochondrial membranes, altering the mitochondria's lipid composition by ... Therefore, various age-related mitochondrial processes are elevated: the membrane potential, the electron transport chain, ATP ... Mitochondrial membrane lipidome defines yeast longevity. Aging 2013, 5, 551-574. Goldberg, AA; Richard, VR; Kyryakov, P; ... The remodelling of the membranes changed the shape and number of mitochondria in the cell by (1) increasing their size, (2) ...
*  Metabolism
Their main structural uses are as part of biological membranes both internal and external, such as the cell membrane, or as a ... Hegardt F (1999). "Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase: a control enzyme in ketogenesis". Biochem J. 338 (Pt ... This is done in eukaryotes by a series of proteins in the membranes of mitochondria called the electron transport chain. In ... The electrons then flow to the cytochrome b6f complex, which uses their energy to pump protons across the thylakoid membrane in ...