*  Tropomyosin
... and one of the most ancient systems is based on filamentous polymers of the protein actin. A second polymer of the protein, ... The actin microfilament system is the fundamental cytoskeletal system involved in the development and maintenance of cell ... such as the Human Genome Project and EST data of expressed proteins that many eukaryotes produce a range of proteins from a ... These proteins consist of rod-shaped coiled-coil hetero- or homo-dimers that lie along the α-helical groove of most actin ...
*  Actin, alpha 1
Actin, alpha skeletal muscle is a protein that in humans is encoded by the ACTA1 gene. Actin alpha 1 which is expressed in ... 1992). "Epidermal growth factor induces rapid reorganization of the actin microfilament system in human A431 cells". J. Cell ... Bretscher A, Weber K (1980). "Villin is a major protein of the microvillus cytoskeleton which binds both G and F actin in a ... SRF may bring a number of other proteins to the promoter of skeletal actin, such as andogen receptor, and thereby contribute to ...
*  Actinin
... is a microfilament protein. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal ... The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore ...
*  Actin depolymerizing factor
... s are a family of microfilament proteins. They are used to regulate actin assembly. Actin ...
*  PFN2
1995). "The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins". EMBO J. 14 (8): 1583-9. PMC ... The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought ... "The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins". EMBO J. ENGLAND. 14 (8): 1583-9. ... 2000). "cAMP-dependent protein kinase phosphorylation of EVL, a Mena/VASP relative, regulates its interaction with actin and ...
*  DIAPH1
"The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins". The EMBO Journal. 14 (8): 1583-9. ... Protein diaphanous homolog 1 is a protein that in humans is encoded by the DIAPH1 gene. This gene is a homolog of the ... Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been ... Fujiwara T, Mammoto A, Kim Y, Takai Y (May 2000). "Rho small G-protein-dependent binding of mDia to an Src homology 3 domain- ...
*  Vasodilator-stimulated phosphoprotein
... and characterization of a zyxin-related protein that binds the focal adhesion and microfilament protein VASP (vasodilator- ... 2000). "Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins ... 1995). "The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins". EMBO J. 14 (8): 1583-9. PMC ... In the mid-region of the protein, family members have a proline-rich region that binds SH3 and WW domain-containing proteins. ...
*  Ezrin
... a microfilament-associated protein". Mol. Biol. Cell. 12 (10): 3060-73. doi:10.1091/mbc.12.10.3060. PMC 60155 . PMID 11598191. ... As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin ... The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli ... "NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ...
*  Palladin
... is a protein that in humans is encoded by the PALLD gene. Palladin is a component of actin-containing microfilaments ... 2002). "Characterization of Human Palladin, a Microfilament-associated Protein". Mol. Biol. Cell. 12 (10): 3060-73. doi:10.1091 ... 2001). "Myopalladin, a Novel 145-Kilodalton Sarcomeric Protein with Multiple Roles in Z-Disc and I-Band Protein Assemblies". J ... a Microfilament-associated Protein". Mol. Biol. Cell. 12 (10): 3060-73. doi:10.1091/mbc.12.10.3060. PMC 60155 . PMID 11598191. ...
*  Zyxin
... and characterization of a zyxin-related protein that binds the focal adhesion and microfilament protein VASP (vasodilator- ... Degenhardt YY, Silverstein S (2001). "Interaction of Zyxin, a Focal Adhesion Protein, with the E6 Protein from Human ... SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein ... Zyxin is a protein that in humans is encoded by the ZYX gene. Focal adhesions are actin-rich structures that enable cells to ...
*  DBN1
2000). "Drebrin is a widespread actin-associating protein enriched at junctional plaques, defining a specific microfilament ... Drebrin is a protein that in humans is encoded by the DBN1 gene. The protein encoded by this gene is a cytoplasmic actin- ... "Infection and Immunity Immunophenotyping (3i) Consortium". Shirao T (1995). "The roles of microfilament-associated proteins, ... 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs ...
*  Microfilament
Microfilaments at the US National Library of Medicine Medical Subject Headings (MeSH) Microfilament proteins at the US National ... including motor proteins, branching proteins, severing proteins, polymerization promoters, and capping proteins. Measuring ... Filament-severing proteins like gelsolin. Actin depolymerizing proteins such as ADF/cofilin. The actin filament network in non- ... Microfilaments are usually about 7 nm in diameter and composed of two strands of actin. Microfilament functions include ...
*  Destrin
... is a component protein in microfilaments. The product of this gene belongs to the actin-binding proteins ADF (Actin- ... This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin ... Destrin or DSTN (also known as actin depolymerizing factor or ADF) is a protein which in humans is encoded by the DSTN gene. ... There are three ordered layers to destrin which is a globular protein. There is a central β sheet that is composed of one ...
*  Espin (protein)
Espin is a microfilament binding protein. Espin is a multifunctional actin-bundling protein. It plays a major role in ... Espin, also known as autosomal recessive deafness type 36 protein or ectoplasmic specialization protein, is a protein that in ... 1998). "Small espin: a third actin-bundling protein and potential forked protein ortholog in brush border microvilli". J. Cell ... 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs ...
*  List of MeSH codes (D05)
... microfilament proteins MeSH D05.750.078.730.032 --- actin capping proteins MeSH D05.750.078.730.032.500 --- capz actin capping ... actin-related protein 2-3 complex MeSH D05.750.078.730.246.500 --- actin-related protein 2 MeSH D05.750.078.730.246.750 --- ... wiskott-aldrich syndrome protein family MeSH D05.750.078.730.912.500 --- wiskott-aldrich syndrome protein MeSH D05.750.078.730. ... photosystem i protein complex MeSH D05.500.562.496 --- photosystem ii protein complex MeSH D05.500.562.500 --- proteasome ...
*  RAVER1
... a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins". The Journal of Cell Biology. 155 ... Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (October 2006). "A probability-based approach for high-throughput protein ... The complete sequences of 50 new cDNA clones which code for large proteins". DNA Research. 8 (6): 319-27. doi:10.1093/dnares/ ...
*  PTBP1
2002). "Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins". J. Cell Biol. ... Polypyrimidine tract-binding protein 1 is a protein that in humans is encoded by the PTBP1 gene. This gene belongs to the ... The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein ... Kim, J H; Hahm B; Kim Y K; Choi M; Jang S K (May 2000). "Protein-protein interaction among hnRNPs shuttling between nucleus and ...
*  Actinin alpha 4
2002). "Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins". J. Cell Biol. ... "Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1". J. Biol. ... "Towards a proteome-scale map of the human protein-protein interaction network". Nature. England. 437 (7062): 1173-8. doi: ... El-Husseini, A E; Kwasnicka D; Yamada T; Hirohashi S; Vincent S R (Jan 2000). "BERP, a novel ring finger protein, binds to ...
*  Index of biochemistry articles
... microfilament - microfilament protein - microsatellite - microscope - microtiter plate - microtubule-associated protein - ... protein - protein biosynthesis - Protein Data Bank - protein design - protein expression - protein folding - protein isoform - ... protein P16 - protein P34cdc2 - protein precursor - protein structure prediction - protein subunit - protein synthesis - ... proto-oncogene protein C-kit - proto-oncogene proteins c-abl - proto-oncogene proteins c-bcl-2 - Proto-oncogene proteins c-fos ...
*  Cytoskeleton
... and they include motor proteins. Microfilaments are composed of linear polymers of G-actin proteins, and generate force when ... Microfilaments are polymers of the protein actin and are 7 nm in diameter. Microtubules are composed of tubulin and are 25 nm ... Microfilaments are composed of the most abundant cellular protein known as actin. During contraction of a muscle, within each ... In general, the major component or protein of microfilaments are actin. The G-actin monomer combines to form a polymer which ...
*  Cell (biology)
The subunit protein of microfilaments is a small, monomeric protein called actin. The subunit of microtubules is a dimeric ... The ER has two forms: the rough ER, which has ribosomes on its surface that secrete proteins into the ER, and the smooth ER, ... They each consist of two subunits, and act as an assembly line where RNA from the nucleus is used to synthesise proteins from ... They are long and thick thread-like appendages, protein in nature. A different type of flagellum is found in archaea and a ...
*  Cleavage (embryo)
Cytokinesis is mediated by the contractile ring made up of polymers of actin protein called microfilaments. Karyokinesis and ... The mitotic apparatus is made up of a central spindle and polar asters made up of polymers of tubulin protein called ... The rapid cell cycles are facilitated by maintaining high levels of proteins that control cell cycle progression such as the ...
*  Actin
Other proteins that bind to actin regulate the length of the microfilaments by cutting them, which gives rise to new active ... of these proteins is such that actin is thought to be the protein that takes part in the greatest number of protein-protein ... or in Hsp70 proteins (a protein family that play an important part in protein folding). G-actin is only functional when it ... An actin protein is the monomeric subunit of two types of filaments in cells: microfilaments, one of the three major components ...
*  Treadmilling
"Actin Binding Proteins: Regulation of Cytoskeletal Microfilaments". Physiological Reviews. 83 (2): 433-473. doi:10.1152/physrev ... This is due to the constant removal of the protein subunits from these filaments at one end of the filament while protein ...
*  Morphogenesis
... and intracellularly to microfilament-binding proteins α-actinin and talin to link the cytoskeleton with the outside. Integrins ... An important class of molecules involved in morphogenesis are transcription factor proteins that determine the fate of cells by ... The organelle consists of microtubules and microfilaments in mechanical opposition. It responds to local mechanical ... Morphogens typically act through binding to specific protein receptors. ...
*  RHOB
2000). "The HIV-1 vpr protein induces anoikis-resistance by modulating cell adhesion process and microfilament system assembly ... Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG". J. Biol. Chem. ... Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG". J. Biol. Chem. ... Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene. RHOB is a ...
*  Matrix (biology)
Integrins span the membrane and bind on the cytoplasmic side to associated proteins attached to microfilaments of the ... The Golgi matrix is a protein scaffold around the Golgi apparatus made up of Golgins, GRASP's and miscellaneous other proteins ... Fibronectin and other ECM proteins bind to cell surface receptor proteins called integrins that are built into the plasma ... In fact, collagen accounts for about 40% of the total protein in the human body. The collagen fibers are embedded in a network ...