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*  Thymus
These mice are an important model of primary T cell deficiency. Severe combined immunodeficiency syndromes (SCID) are group of ... A fully functional thymus derived from reprogrammed mouse embryonic fibroblasts has been grown in the kidney capsule of mice. ... In mice, the nude mouse strain are congenitally thymic deficient. ... and upon transplantation it was able to restore immune function in immunocompromised mice. The mouse embryonic fibroblasts were ...
*  Bare lymphocyte syndrome type II
"SCID due to absent class II HLA antigens (Concept Id: C0242583) - MedGen - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2017-07-28. ... of mice and men". Human Immunology. 65 (4): 282-290. doi:10.1016/j.humimm.2004.01.005. ISSN 0198-8859. PMID 15120183. - via ...
*  Taenia asiatica
Moreover, SCID mice and Mongolian gerbil can be experimentally infected. The life cycle is basically similar to those of other ...
*  Helicobacter rodentium
Myles MH, Livingston RS, Franklin CL (October 2004). "Pathogenicity of Helicobacter rodentium in A/JCr and SCID mice". ... Its type strain is MIT 95-1707 (= ATCC 700285). Its name refers to the species first being isolated from mice. Shen, Z.; Fox, J ... Feng, S.; Ku, K.; Hodzic, E.; Lorenzana, E.; Freet, K.; Barthold, S. W. (2005). "Differential Detection of Five Mouse-Infecting ... nov., a Urease-Negative Helicobacter Species Isolated from Laboratory Mice". International Journal of Systematic Bacteriology. ...
*  Isotype (immunology)
Smith, C. I., Hassan, M. S. (1991). "Biological half-life of normal and truncated human IgG3 in scid mice". Eur J Immunol. ...
*  Helicobacter bilis
"Helicobacter bilis-induced inflammatory bowel disease in scid mice with defined flora". Infection and Immunity. 65 (11): 4858- ... 2000]. H. rappini has also been isolated from the feces of healthy people, dogs, and mice, as well as from patients with ... Like Helicobacter hepaticus, it colonizes the bile, liver, and intestine of mice, and is associated with multifocal chronic ... nov., a novel Helicobacter species isolated from bile, livers, and intestines of aged, inbred mice". Journal of Clinical ...
*  Tumour heterogeneity
"High level engraftment of NOD/SCID mice by primitive normal and leukemic hematopoietic cells from patients with chronic myeloid ... "A cell initiating human acute myeloid leukaemia after transplantation into SCID mice". Nature. 367 (6464): 645-648. doi:10.1038 ... Cancer stem cell Somatic evolution in cancer Genome instability Mouse models of breast cancer metastasis Marusyk, A; Polyak, K ...
*  John Edgar Dick
Dick developed an in vivo repopulation assay using the NOD/SCID mouse. This technique of using an immune-deficient mouse to ... "A cell initiating human acute myeloid leukaemia after transplantation into SCID mice". Nature. 367 (6464): 645-8. doi:10.1038/ ... "Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene ... Dick is also known for his demonstration of a blood stem cell's ability to replenish the blood system of a mouse, his ...
*  LAPC4
"Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice". Nature Medicine. 3 (4 ... the lymph node metastasis of a male patient with hormone refractory prostate cancer which was then xenografted into SCID mice ...
*  Fox Chase Cancer Center
1980 Discovery of the SCID mouse, a mouse strain with no natural immunity, by Melvin Bosma. The SCID mouse is an essential ... 1981 Beatrice Mintz's laboratory is one of the first to introduce a cloned gene into fertilized mouse eggs and prove that it is ... 1979 Beatrice Mintz shows that a fatal genetic anemia of mice can be prevented in utero by injecting normal blood-forming stem ... 1993 Beatrice Mintz produces the first mouse model of human malignant melanoma, in which the disease resembles the human ...
*  NSG mouse
NOD scid gamma mice (NSG mice) is a brand of immunodeficient laboratory mice developed and marketed by The Jackson Laboratory ... 2008). "A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in ... NSG branded mice lack mature T cells, B cells, and natural killer (NK) cells. NSG branded mice are also deficient in multiple ... 2005). "Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human ...
*  Brian V. Jegasothy
"Establishment of a Human Cutaneous T-Cell Lymphoma in C.B-17 SCID Mice". Journal of Investigative Dermatology. 94: 381-384. doi ...
*  Dean H. Kedes
KSHV targets multiple leukocyte lineages during long-term productive infection in NOD/SCID mice. JOURNAL OF CLINICAL ...
*  NOG mouse
Cancer Infectious Diseases Regenerative Medicine Hematology Humanized mouse Nude mouse SCID mouse M. Ito and, et al. (2002). " ... nude mouse and NOD/scid mouse. Thus, the mouse can be the best model as a highly efficient recipient of human cells to engraft ... A NOG (NOD/Shi-scid/IL-2Rγnull) mouse is a new generation of severely immunodeficient mouse, developed by Central Institute for ... "NOD/SCID/γnull mouse: an excellent recipient mouse model for engraftment of human cells". Blood. 100 (9): 3175-3182. doi: ...
*  DNA damage theory of aging
"DNA repair kinetics in SCID mice Sertoli cells and DNA-PKcs-deficient mouse embryonic fibroblasts". Chromosoma. 126 (2): 287- ... However, in mice there is no increase in mutation in the brain with aging. Mice defective in a gene (Pms2) that ordinarily ... mutant mice defective in Ku70, or Ku80, or double mutant mice deficient in both Ku70 and Ku80 exhibit early aging. The mean ... and the three mutant mice were found to display the same aging signs as the control mice, but at a much earlier age. Cancer ...
*  Ronald S. Weinstein
"Development of an orthotopic SCID mouse-human tumor xenograft model displaying the multidrug-resistant phenotype". Cancer ... WEINSTEIN, R. "Effects of continuous inhalation of dichloromethane in the mouse: Morphologic and functional observations*1". ...
*  DNA repair-deficiency disorder
"DNA repair kinetics in SCID mice Sertoli cells and DNA-PKcs-deficient mouse embryonic fibroblasts". Chromosoma. 126 (2): 287- ... Tian M, Jones DA, Smith M, Shinkura R, Alt FW (2004). "Deficiency in the nuclease activity of xeroderma pigmentosum G in mice ... Bonsignore LA, Tooley JG, Van Hoose PM, Wang E, Cheng A, Cole MP, Schaner Tooley CE (2015). "NRMT1 knockout mice exhibit ... Hasty P, Campisi J, Hoeijmakers J, van Steeg H, Vijg J (February 2003). "Aging and genome maintenance: lessons from the mouse ...
*  Sphingosine-1-phosphate
S1P has protected ovarian tissue xenografts in SCID mouse models from radiation induced atresia. In animal models these ... September 2002). "Sphingosine 1-phosphate preserves fertility in irradiated female mice without propagating genomic damage in ... September 2006). "Sphingosine-1 phosphate prevents monocyte/endothelial interactions in type 1 diabetic NOD mice through ... "Sphingosine-1-Phosphate Prevents Tumor Necrosis Factor-α-Mediated Monocyte Adhesion to Aortic Endothelium in Mice". ...
*  Taconic Biosciences
1985 - Started producing BALB/c mice. 1991 - Became the first commercial provider of the C.B-17 SCID mouse model. 1994 - ... They continue to supply NCI with BDF1 mice. 1975 - Began offering the SHR hypertensive rat and the WKY control strain. 1980 - ... 1949 - Robert Phelan began shipping mice from his garage in Canajoharie, NY. 1952 - Taconic Farms is officially founded in ... 1963 - Contracted to provide BDF1 mice for the National Cancer Institute. 1969 - Began offering rats, including Sprague Dawley ...
*  CD47
... administration of the antibody prolonged survival of SCID mice implanted with JOK-1 cells. Apoptosis induction appears to be ... In a mouse model of multiple myeloma, tumor metastasis to bone was decreased in CD47-deficient mice compared with wild type ... In mice xenografted with human non-Hodgkin lymphoma (NHL) cells, blocking CD47 function with shRNA or antibodies led to a ... CD47 knockout mice show reduced recruitment of blood T cells as well as neutrophils and monocytes in areas of inflammation. ...
*  Fiona Powrie
B-17 scid mice". International Immunology. 5 (11): 1461-71. doi:10.1093/intimm/5.11.1461. PMID 7903159. Powrie F, Leach MW, ... CD45RBhi T cells to Rag deficient or SCID mice led to the development of severe intestinal inflammation and wasting disease. ... Mauze S, Menon S, Caddle LB, Coffman RL (1994). "Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice ... This work identified that CD4+OX22hi (OX22 is CD45RC in rats and the equivalent of CD45RB in mice, both isoforms of CD45) T ...
*  Sleeping Beauty transposon system
"Systemic correction of storage disease in MPS I NOD/SCID mice using the sleeping beauty transposon system". Mol. Ther. 17 (7): ... When a gene is inactivated by insertion of a transposon (or other mechanism), that gene is "knocked out". Knockout mice and ... Dupuy AJ (August 2010). "Transposon-based screens for cancer gene discovery in mouse models". Semin. Cancer Biol. 20 (4): 261- ... Carlson CM, Largaespada DA (July 2005). "Insertional mutagenesis in mice: new perspectives and tools". Nat. Rev. Genet. 6 (7): ...
*  Transfusion transmitted infection
... isolation of Babesia microti-like parasites with hu-RBC-SCID mice. "UK buys "safe" blood supply for NHS". British Broadcasting ...
*  BCP-1 cells
... from peripheral blood and characterizing its growth in Nod/SCID mice". Blood. 91 (5): 1671-9. PMID 9473233. Cellosaurus entry ...
*  Non-specific effect of vaccines
In SCID mice that have no adaptive immune system, BCG reduced mortality from an otherwise lethal candida infection. The effects ...
*  Follicular dendritic cells
Severe combined immunodeficiency (SCID) mice models demonstrate that these precursors may be transmitted to recipients with ... Deficit of this factor in mice leads to a state resembling systemic lupus erythematosus (SLE). Furthermore, mice lacking LT or ... In mice lacking B cells, or with blocked TNF-a and lymphotoxin (LT) production, cells with FDC phenotype are missing. In normal ... "Impaired prion replication in spleens of mice lacking functional follicular dendritic cells". Science. 288 (5469): 1257-9. doi: ...
*  Helicobacter muridarum
Jiang HQ, Kushnir N, Thurnheer MC, Bos NA, Cebra JJ (May 2002). "Monoassociation of SCID mice with Helicobacter muridarum, but ... Feng, S.; Ku, K.; Hodzic, E.; Lorenzana, E.; Freet, K.; Barthold, S. W. (2005). "Differential Detection of Five Mouse-Infecting ... with Enterohepatic Helicobacter Species Can Ameliorate or Promote Helicobacter pylori-Induced Gastric Pathology in C57BL/6 Mice ...