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*  Nippostrongylus brasiliensis
The availability of inbred and mutant mouse strains can be advantageous when examining the genetic basis of murine ... Characterization of Nippostrongylus brasiliensis infection in different strains of mice. The Journal of Parasitology 76:377-382 ... Studies performed on lab mice revealed that mice previously infected with N. brasiliensis had developed massive emphysema with ... The life-cycle of N. brasiliensis can be passed through lab mice and due to this parasite is invaluable when it comes to being ...
*  Laboratory mouse
Various mutant strains of mice have been created by a number of methods. A small selection from the many available strains ... inbred mouse strain and initiated the systematic generation of inbred strains. The mouse has since been used extensively as a ... "BALB/c". Inbred Strains of Mice. Jackson Laboratory. Retrieved 2007-04-16. "BALB/cByJ". Jax Mice Data Sheet. Jackson Laboratory ... The laboratory is also the world's source for more than 8,000 strains of genetically defined mice and is home of the Mouse ...
*  History of model organisms
He began developing large, mutant strain, colonies of mice. Under the charge of Dr. William Castle, Little helped to expand the ... 30-35 Rader, Making Mice Rader, Making Mice, pp. 190-195 Rader, Making Mice, p. 252 Allen, Garland E. Thomas Hunt Morgan: The ... in mice was one that may have created a negative response to the fertility of the mice thus discontinuing the strain. Little ... This necessity for funds all but stopped the continuation of these strains of mice. The transition for these laboratories to ...
*  DNA damage theory of aging
... or double mutant mice deficient in both Ku70 and Ku80 exhibit early aging. The mean lifespans of the three mutant mouse strains ... and the three mutant mice were found to display the same aging signs as the control mice, but at a much earlier age. Cancer ... A mouse mutant with a defect in this DNA polymerase is only able to replicate its mitochondrial DNA inaccurately, so that the ... However, in mice there is no increase in mutation in the brain with aging. Mice defective in a gene (Pms2) that ordinarily ...
*  Ku (protein)
... or double mutant mice deficient in both Ku70 and Ku80 exhibit early aging. The mean lifespans of the three mutant mouse strains ... and the three mutant mice were found to display the same aging signs as the control mice, but at a much earlier age. Cancer ... Both subunits of Ku have been experimentally knocked out in mice. These mice exhibit chromosomal instability, indicating that ... incidence was not increased in the mutant mice. These results suggest that Ku function is important for longevity assurance and ...
*  Mary F. Lyon
... where she characterised a mutant mice strain with a 'pallid' mutation and published the research. During the course of her PhD ... She also scrutinised a 'mottled' mutant, which had a different effect on male and female mice: male embryos sometimes died, and ... where there was room for more mouse facilities. There she continued to investigate the mouse mutations. ... She also did extensive work on the mouse t-complex. She was head of the Genetics Section of the MRC Radiology Unit at Harwell ...
*  Eyeblink conditioning
Classical conditioning of a Purkinje cell deficient mutant mouse strain helped to determine the extent to which spared regions ... Results of conditioning were similar to the cortical aspiration mice. Mice took significantly longer to produce CRs, and the ... These mice are born with PCs that die after about 3 weeks of life. Because PCs are the sole output neuron of the cortex, this ... including mice, rats, guinea pigs, rabbits, ferrets, cats, and humans. Historically, rabbits have been the most popular ...
*  International Mouse Phenotyping Consortium
Mouse strains generated by the IMPC partners are deposited at the KOMP repository and the European Mutant Mouse Archive. In ... "Knockout Mouse Project (KOMP) Repository". KOMP. 2010-08-01. Retrieved 2013-08-01. "EMMA - the European Mouse Mutant Archive". ... standardized protocols that are used by mouse research clinics to assess biological characteristics of mutant mouse strains. ... developed more than a 150 standardized protocols for the characterization of mutant mouse strains across European research ...
*  HRAS
Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects". Nature Genetics. 26 (1): 109-113. doi:10.1038 ... Tennant RW, Stasiewicz S, Eastin WC, Mennear JH, Spalding JW (2002). "The Tg.AC (v-Ha-ras) transgenic mouse: nature of the ... "Mouse PubMed Reference:". Wong-Staal F, Dalla-Favera R, Franchini G, Gelmann EP, Gallo RC (Jul 1981). "Three distinct genes in ...
*  Earmark (agriculture)
Earmarking a mutant strain of mice called MRL/MpJ led to the accidental discovery that they had the ability to regenerate ... It was later found that this strain of mice also heals damage to other body parts such as knee cartilage and heart muscle ... Laboratory mice are often kept with several animals in one cage since mice are social animals, therefore it is necessary to ... Microchips are less commonly used in mice because of their expense compared to the short life span of a mouse. ...
*  PDE6B
The albino FVB mouse laboratory strain become blind by weaning age due to a mutant allele of the PDE6b gene. There are ... Chang B, Hawes NL, Hurd RE, Davisson MT, Nusinowitz S, Heckenlively JR (Feb 2002). "Retinal degeneration mutants in the mouse ... pigmented derivative strains of FVB that lack this trait. Similar to rd1 in mice, Rod-cone dysplasia type 1 (rcd1-PRA) is a ... The rd1 mouse is a well-characterized animal model of retinitis pigmentosa caused by the mutation of Pde6b gene. The phenotype ...
*  Consortium for Functional Glycomics
All Core F strains are now archived at the Mutant Mouse Regional Resource Center (MMRRC) at the University of California, Davis ... At the discretion of the Mouse Subcommittee, Core G also occasionally evaluates mouse lines provided by investigators. Protein- ... Mouse Transgenics Core (F), formerly located at The Scripps Research Institute, is now closed. From 2001-2009, Core F generated ... Mouse Phenotype Core (G), located at the Sanford-Burnham Medical Research Institute, works with participating investigator " ...
*  Mouse News Letter
These included lists and maps of mouse genes and mutants, information on inbred strains, and brief reports of useful results ... 1997). A Life Story of Mouse News Letter and Mouse Genome. Mouse Genome 95:818-820. Searle AG. (1974). "The origins of Mouse ... This replaced Inbred Strains of Mice. The journal was run by a company Mouse News Letter Ltd, limited by guarantee and with ... 1996). "Chapter 4: Mouse Chromosome Atlas" in Genetic Variants and Strains of the Laboratory Mouse 3rd Edition Eds MF Lyon, S. ...
*  Staphyloxanthin
Wounds on mice were inoculated with the two strains. The pigmented strains created lingering abscesses. Wounds with the ... Colonies of the two strains were also exposed to human neutrophils. The mutant colonies quickly succumbed while many of the ... When comparing a normal strain of S. aureus with a strain modified to lack staphyloxanthin, the wildtype pigmented strain was ... more likely to survive incubation with an oxidizing chemical such as hydrogen peroxide than the mutant strain was. ...
*  Pygmy mouse
Thomas's pygmy mouse (Mus sorella) Gray-bellied pygmy mouse (Mus triton) Pygmy mouse (mutant) (pg), a mutant strain of the ... South African Pygmy Mouse, or just Pygmy Mouse (Mus minutoides) Subsaharan pygmy mouse (Mus musculoides) Free State pygmy mouse ... Pygmy mouse may refer to: Baiomys, a North American genus: Northern pygmy mouse (Baiomys taylori) Southern pygmy mouse (Baiomys ... musculus) Nannomys, an African subgenus: Desert pygmy mouse (Mus indutus) African pygmy mouse, ...
*  Carboxypeptidase E
Mice with mutant carboxypeptidase E, Cpefat, display endocrine disorders like obesity and infertility. In some strains of mice ... but this is not found in all strains of mice. The obesity and infertility in the Cpefat mice develop with age; young mice (. 50 ... This patient had intellectual disability (inability to read or write) and had abnormal glucose homeostasis, similar to mice ... mice". Cell. 88 (1): 73-83. doi:10.1016/S0092-8674(00)81860-7. PMID 9019408. Maeda K, Okubo K, Shimomura I, Mizuno K, Matsuzawa ...
*  Rat Genome Database
... congenic strains) or the location of the mutated sequence (mutant strains). RGD does not import data for mouse strains. Markers ... parental strains or substrains) and, where available, strain-specific nucleotide variants. For congenic and mutant strains, ... Strain Medical Records: RGD's Strain Medical Records (SMR) are designed to consolidate what is known about a particular strain ... Strain records include information about the origin and availability of the strain, associated phenotypes, whether the strain ...
*  Alexander Fleming Biomedical Sciences Research Center
Its main activity is the reproduction and maintenance of mice stocks either of inbred strains or genetically engineered mice, ... such as transgenic and knockout mouse lines, as well as chemically induced mutants developed by Fleming researchers. The Animal ... Fleming operates its own Animal House, which can house up to 20,000 mice and has its own complete mouse histopathology unit. ... to house more than 20,000 mice and is currently the largest Mouse Unit in Greece in terms of number and variety of mice. The ...
*  Animal model of schizophrenia
... heterozygous mutants can be produced by crossing sdy mice with a strain of normal mice. Play media Reelin is a protein which is ... As of 2011, seven different strains of DISC1 mouse models had been developed. As in schizophrenia patients, DISC1 mice have an ... Knockout mice in which the reelin gene is disrupted are called reeler mice. In homozygous reeler mice, extreme changes in gait ... mouse, has a number of anatomical changes compared to normal mice, including changes to the hippocampus. Sdy mice have ...
*  Harlan (company)
... mice, gerbils, and hamsters, as well as hybrid, mutant, and transgenic animals. Its brochure says it supplies more stocks and ... and stock and strain elimination. It also provides contract research services, which comprise toxicology, environmental science ... strains of lab animals than any other commercial supplier in the world. BUAV writes that the company breeds around 450 baby ...
*  Staphylococcus aureus
Mutant strains of S. aureus modified to lack staphyloxanthin are less likely to survive incubation with an oxidizing chemical, ... Mutant colonies are quickly killed when exposed to human neutrophils, while many of the pigmented colonies survive. In mice, ... whereas wounds infected with the unpigmented strains quickly heal. These tests suggest the Staphylococcus strains use ... Other strains of S. aureus can produce an enterotoxin that is the causative agent of a type of gastroenteritis. This form of ...
*  Marfan syndrome
A transgenic mouse has been created carrying a single copy of a mutant fibrillin-1, a mutation similar to that found in the ... This mouse strain recapitulates many of the features of the human disease and promises to provide insights into the ... Reducing the level of normal fibrillin 1 causes a Marfan-related disease in mice. Transforming growth factor beta (TGF-β) plays ... 1999). "Pathogenetic sequence for aneurysm revealed in mice underexpressing fibrillin-1". Proceedings of the National Academy ...
*  Staphylococcus aureus alpha toxin
... aureus directly correlates with the virulence of the strain. Recent research has shown that immunization with a mutant form of ... alpha-toxin that is no longer able to form pores protects against S. aureus pneumonia in mice. Also, introduction of alpha- ... As many strains of S. aureus are proving to be resistant to most available antibiotics, specific targeting of virulence factors ... Alpha-toxin has been shown to play a role in pathogenesis of disease, as hla knockout strains show reductions in invasiveness ...
*  List of MeSH codes (B01)
... mice, inbred sencar MeSH B01.150.900.649.865.635.505.500.550 --- mice, mutant strains MeSH B01.150.900.649.865.635.505.500. ... mice, inbred strains MeSH B01.050.157.520.300 --- mice, inbred a MeSH B01.050.157.520.318 --- mice, inbred akr MeSH B01.050. ... mice, inbred strains MeSH B01.050.199.520.520.300 --- mice, inbred a MeSH B01.050.199.520.520.318 --- mice, inbred akr MeSH ... Knockout mice,mice, knockout MeSH B01.150.900.649.865.635.505.500.550.480 --- mice, neurologic mutants MeSH B01.150.900.649. ...
*  Human mortality from H5N1
Significantly, mouse antibodies were 10 times less potent against the mutants than against the pre-mutated viruses. A graphic ... This strain caused asymptomatic infections in humans and may have died out, like the 1959 strain, so that its low mortality ... This relatively benign Korean strain of H5N1 has died out, and the remaining strains of H5N1 have a higher case fatality rate ... In fact, when less-virulent strains die off, the surviving strains are the more virulent. Such difficulties in interpretation ...
*  PDCD10
Twenty five tests were carried out on mutant mice and two significant abnormalities were observed. No homozygous mutant embryos ... doi:10.1161/01.STR.0000183616.99139.d3. PMID 16239636. Guclu B, Ozturk AK, Pricola KL, Bilguvar K, Shin D, O'Roak BJ, Gunel M ( ... The remaining tests were carried out on heterozygous mutant adult mice; no additional significant abnormalities were observed ... A conditional knockout mouse line, called Pdcd10tm1a(KOMP)Wtsi was generated as part of the International Knockout Mouse ...