"BALB/c". Inbred Strains of Mice. Jackson Laboratory. Retrieved 2007-04-16. "BALB/cByJ". Jax Mice Data Sheet. Jackson Laboratory ... When compared directly to BALB/c mice, C57BL/6 mice also express both a robust response to social rewards and empathy. BALB/c ... BALB/c mice are distributed globally and are among the most widely used inbred strains used in animal experimentation. BALB/c ... inbred mouse strain and initiated the systematic generation of inbred strains. The mouse has since been used extensively as a ...
Schwartz WJ, Zimmerman P. Circadian timekeeping in BALB/c and C57BL/6 inbred mouse strains. J Neurosci. 1990; 10: 3685-3694. ...
1985 - Started producing BALB/c mice. 1991 - Became the first commercial provider of the C.B-17 SCID mouse model. 1994 - ... Contracted with National Institute for Allergy and Infectious Disease to maintain a repository of inbred, congenic, and ... "Mice in microgravity: how rodent research in space accelerates study timelines". outsourcing-pharma.com. Retrieved 9 June 2017 ... They continue to supply NCI with BDF1 mice. 1975 - Began offering the SHR hypertensive rat and the WKY control strain. 1980 - ...
Mouse NLRP1B is not activated by a receptor-ligand type mechanism. NLRP1B variants from certain inbred mouse strains, BALB/c ... "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine. Thorpe KL, Abdulla ... Mice have three paralogs of the Nlrp1 gene (Nlrp1a, b, c). Nlrp1c is a pseudogene. ... Polymorphisms of NLRP1 were found in lupus erythematosus and diabetes type 1. Variants of mouse NLRP1 were found to be ...
Some inbred laboratory mouse strains, such as BALB/c and C57BL/6, also have different proteins expressed in their urine. ... using white-footed mice, it was found that when mice derived from wild populations were inbred, there was reduced survival when ... Wild mice breeding freely in semi-natural enclosures showed inbreeding avoidance. This avoidance resulted from a strong deficit ... These findings suggest that inbreeding reduces fitness, and that scent signal recognition has evolved in mice as a means of ...
... and only three un-pedigreed mice remained alive. Soon after World War I, inbreeding in mice was started on a much larger scale ... A/J C3H C57BL/6 CBA DBA/2 BALB/c G. M. Rommel first started conducting inbreeding experiments on guinea pigs in 1906. Strain 2 ... "The period before World War I led to the initiation of inbreeding in rats by Dr Helen King in about 1909 and in mice by Dr C. C ... A genealogical chart of mouse inbred strains can be found here on the Jackson Laboratory website and is currently being ...
Mice of the inbred strain BALB/c were immunized with recombinant human CD28-Fc fusion proteins and boosted with a B lymphoma ... Animal trials on mice were not necessarily predictive of human responses, as it would require a much greater dosage to get the ... In 2016, a study carried out on humanized mice evaluated TGN1412's effects on the immune system, and confirmed that it could ... The more active of the two, 5.11A1, is a mouse IgG1 immunoglobulin. The complementarity-determining regions of 5.11A1 were ...
... mice, inbred a MeSH B01.050.157.520.318 - mice, inbred akr MeSH B01.050.157.520.338 - mice, inbred balb c MeSH B01.050.157.520. ... mice, inbred a MeSH B01.050.199.520.520.318 - mice, inbred akr MeSH B01.050.199.520.520.338 - mice, inbred balb c MeSH B01.050. ... mice, inbred mdx MeSH B01.050.157.520.440 - mice, inbred cba MeSH B01.050.157.520.445 - mice, inbred cftr MeSH B01.050.157.520. ... mice, inbred hrs MeSH B01.050.157.520.510 - mice, inbred icr MeSH B01.050.157.520.555 - mice, inbred mrl lpr MeSH B01.050. ...
In the case of a typical mouse recombinant inbred strain made by crossing maternal strain BALB/cBy (C) with paternal strain ... Recombinant inbred strains or lines were first developed using inbred strains of mice but are now used to study a wide range of ... pairs of the F2 progeny are then mated to establish inbred strains through long-term inbreeding. Families of recombinant inbred ... Williams RW, Gu J, Qi S, Lu L (2001). "The genetic structure of recombinant inbred mice: high-resolution consensus maps for ...
Examples include the BALB/c mouse and Wistar and Sprague Dawley rat strains, laboratory rabbits and ferrets. Some researchers ... Familiar albino animals include in-bred strains of laboratory animals (rats, mice and rabbits), but populations of naturally ... In mice, a total of 100 genes are known to affect albinism. Most forms of albinism follow a recessive pattern of inheritance. ... Brilliant, Murray H. (2001). "The Mouse p (pink-eyed dilution) and Human P Genes, Oculocutaneous Albinism Type 2 (OCA2), and ...
"Dirty" mice are possibly better suitable for mimicking human pathologies. In addition, inbred mouse strains are used in the ... Animal testing Animal model BALB/c C57BL/6 Fe, Fi, Fo, Fum, and Phooey, five mice who orbited the Moon in 1972 Mouse models of ... Mice differ from humans in several immune properties: mice are more resistant to some toxins than humans; have a lower total ... Thirty to fifty live mice are normally born from this number of injected blastocysts. Normally, the skin color of the mice from ...
... several strains of mice (including BALB/c mice) and in three common monkey species. In addition to natural killer cells being ... Smith HJ (December 1966). "Antigenicity of carcinogen-induced and spontaneous tumours in inbred mice". British Journal of ... in the mouse, and by Hugh Pross and doctoral student Mikael Jondal in the human. The mouse and human work was carried out under ... In both mice and humans, NKs can be seen to play a role in tumor immunosurveillance by directly inducing the death of tumor ...