... of the potency of metiamide) however, the NH form (the guanidine analog of metiamide) did not show agonistic effects to prevent ... Metiamide is a histamine H2 receptor antagonist developed from another H2 antagonist, burimamide. It was an intermediate ... The clinical trials that began in 1973 demonstrated the ability of metiamide to provide symptomatic relief for ulcerous ... Finally, condensation of the amine with methyl isothiocyanate gives metiamide (6). Clayden, Jonathan; Greeves, Nick; Warren, ...

The discovery of burimamide ultimately led to the development of cimetidine (Tagamet). Metiamide Cimetidine Clayden, Jonathan; ...

... led to the development of metiamide. Metiamide was an effective agent; however, it was associated with unacceptable ...

... led to the development of metiamide. Metiamide was an effective agent; it was associated, however, with unacceptable ...

"Inhibition of nocturnal acid secretion in duodenal ulcer by one oral dose of metiamide". Lancet. 1 (7860): 693-4. doi:10.1016/ ... "Relief of Duodenal Ulcer Symptoms By Oral Metiamide". The British Medical Journal. 2 (5966): 307-309. doi:10.1136/bmj.2.5966. ...

They quickly identified a similar drug, metiamide, which appeared to have clinical potential. However, metiamide also had a ... The end result of their trials was cimetidine, an H2-receptor antagonist superior to both burimamide and metiamide. The ...

... burimamide and metiamide. Recent studies have found that phosphodiesterase 4 (PDE4) inhibitors, such as Rolipram, cause emesis ...

Meti-Derm Metiamide (INN) Metiapine (INN) Metiazinic acid (INN) Metibride (INN) Meticillin (INN) Meticortelone Meticorten ...

... metiamide MeSH D02.886.904.500 - noxythiolin MeSH D02.886.904.601 - phenylthiourea MeSH D02.886.904.601.600 - ... metiamide MeSH D02.948.898.500 - noxythiolin MeSH D02.948.898.601 - phenylthiourea MeSH D02.948.898.601.600 - ...