N-methylurea, and related compounds". Canadian Journal of Biochemistry. 58 (12): 1335-1344. doi:10.1139/o80-181. PMID 6788353. ...
Most of these compounds cause DNA damage by forming DNA adducts or by inducing other alterations in DNA.[citation needed] DNA ... Genotoxins include chemical agents like N-nitroso-N-methylurea (NMU) or non-chemical agents such as ultraviolet light and ... These include hormones and some organic compounds. The International Agency for Research on Cancer (IARC) is an ... Using this approach, the most important tumorigenic compounds in tobacco smoke were, in order of importance, acrolein, ...
The compound is basically a conjugate between the well-known cytotoxic and mutagenic residue of N-nitroso-N-methylurea and the ... improved tolerability over other nitrosourea antineoplastic compounds available at that time. In 1996 the compound obtained a ...
The formation of an reactive epoxide, leads to the formation of the compounds mentioned. Experiments in man indicated the major ... Another pathway for hexobarbital synthesis is reacting methylcyclohexenylcyanoacetic acid ethyl ester with N-methylurea. This ... "COMPOUNDS USEFUL AS MODULATORS OF TRPM8". worldwide.espacenet.com. Retrieved 2021-03-07.CS1 maint: multiple names: authors list ... The Fate of Foreign Compounds in Biological Systems. 23 (8): 925-34. doi:10.3109/00498259309059419. PMID 8284947. Smith, D. A ...
... may refer to: Compounds sharing the molecular formula: Biuret N-Nitroso-N-methylurea This set index page lists ...
The traditional precursor is N-nitroso-N-methylurea, but this compound is itself somewhat unstable, and nowadays compounds such ... The compound is a popular methylating agent in the laboratory, but it is too hazardous to be employed on an industrial scale ... The compound explodes when heated beyond 100 °C, exposed to intense light, alkali metals, or calcium sulfate. Use of a blast ... It is the simplest diazo compound. In the pure form at room temperature, it is an extremely sensitive explosive yellow gas; ...
Nimustine N-Nitroso-N-methylurea (NMU) Ranimustine (MCNU) Semustine Streptozocin (Streptozotocin) Nitrosourea compounds are DNA ... Nitrosourea is both the name of a molecule, and a class of compounds that include a nitroso (R-NO) group and a urea. Examples ... Nitrosourea+Compounds at the US National Library of Medicine Medical Subject Headings (MeSH) Diseases Database (DDB): 9052 v t ... Arabinopyranosyl-N-methyl-N-nitrosourea Carmustine Chlorozotocin Ethylnitrosourea Fotemustine Lomustine N-Nitroso-N-methylurea ...
... it has become obsolete for this purpose and replaced by other N-nitroso compounds: (N-methyl)nitrosamides and nitrosamines. ... N-Nitroso-N-methylurea (NMU) is a highly reliable carcinogen, mutagen, and teratogen. NMU is an alkylating agent, and exhibits ...
Most of these compounds cause DNA damage by forming DNA adducts or by inducing other alterations in DNA.[33] DNA damages are ... Genotoxins include chemical agents like N-nitroso-N-methylurea (NMU) or non-chemical agents such as ultraviolet light and ... Dioxins and dioxin-like compounds, benzene, kepone, EDB, and asbestos have all been classified as carcinogenic.[6] As far back ... the most important tumorigenic compounds in tobacco smoke were, in order of importance, acrolein, formaldehyde, acrylonitrile, ...
Most of these compounds cause DNA damage by forming DNA adducts or by inducing other alterations in DNA.[citation needed] DNA ... Genotoxins include chemical agents like N-nitroso-N-methylurea (NMU) or non-chemical agents such as ultraviolet light and ... Dioxins and dioxin-like compounds, benzene, kepone, EDB, and asbestos have all been classified as carcinogenic.[6] As far back ... Beyersmann, Detmar; Hartwig, Andrea (2008). "Carcinogenic metal compounds: Recent insight into molecular and cellular ...
Cole studied the origins of the nonlinear optics observed in N-methylurea, where solid-state intermolecular interactions and ... Structural studies of organic and organometallic compounds using x-ray and neutron techniques (PhD thesis). Durham University. ... "Molecular and Supramolecular Origins of Optical Nonlinearity in N-Methylurea". The Journal of Physical Chemistry C. 117 (48): ... Structural studies of organic and organometallic compounds using x-ray and neutron techniques, described the structure-property ...
The traditional precursor is N-nitroso-N-methylurea, but this compound is itself somewhat unstable, and nowadays compounds such ... The compound is a popular methylating agent in the laboratory, but it is too hazardous to be employed on an industrial scale ... The compound explodes when heated beyond 100 °C, exposed to intense light, alkali metals, or calcium sulfate. Use of a blast ... Related compounds. Diazomethane is both isomeric and isoelectronic with the more stable cyanamide, but they cannot interconvert ...
Derivatives of these compounds include epirubicin and idarubicin. Other clinically used drugs in the anthracycline group are ... Nitrosoureas include N-Nitroso-N-methylurea (MNU), carmustine (BCNU), lomustine (CCNU) and semustine (MeCCNU), fotemustine and ... The first modern chemotherapeutic agent was arsphenamine, an arsenic compound discovered in 1907 and used to treat syphilis. ... Liu YQ, Yang L, Tian X (2007). "Podophyllotoxin: current perspectives". Current Bioactive Compounds. 3 (1): 37-66. doi:10.1016/ ...
Nitrosoureas include N-Nitroso-N-methylurea (MNU), carmustine (BCNU), lomustine (CCNU) and semustine (MeCCNU), fotemustine and ... Current Bioactive Compounds. 3 (1): 37-66. doi:10.1016/j.jallcom.2006.06.070.. CS1 maint: Multiple names: authors list (link) ... an arsenic compound discovered in 1907 and used to treat syphilis.[146] This was later followed by sulfonamides (sulfa drugs) ... Derivatives of these compounds include epirubicin and idarubicin. Other clinically used drugs in the anthracyline group are ...
In the final step, reaction of the disubstituted malonic ester with N-methylurea gives methohexital. ... Bromide compounds (e.g., lithium bromide, potassium bromide, sodium bromide). *Carbamazepine. *Chloralose ...