Methylcholanthrene
... is also known as 3-methylcholanthrene, 20-methylcholanthrene or the IUPAC name 3-methyl-1,2-dyhydrobenzo[j] ... The most common isomer is 3-methylcholanthrene, although the methyl group can occur in other places. 3-Methylcholanthrene, a ... Methylcholanthrene is often tested on mice and rats to derive information for cancer medicine development. Due to the influence ... Methylcholanthrene is often used to induce tumors in rodents for carcinogenesis and mutagenesis research. In a study from 1991 ...
Zola Cooper
Cooper, Zola K.; Firminger, Harlan I.; Reller, Helen C. (October 1944). "Transplantable Methylcholanthrene Skin Carcinomas of ... 17: 589-. Cooper, Zola K.; Reller, Helen C. (February 1942). "Mitotic Frequency in Methylcholanthrene Epidermal Carcinogenesis ...
Glioma 261
Seligman AM, Shear MJ (1939). "Experimental production of brain tumors in mice with methylcholanthrene". Am J Cancer. 37: 364- ... It was induced via intracranial injection of methylcholanthrene followed by serial intracranial and subcutaneous ...
Alfred G. Gilman
Gilman, AG; Conney, AH (1963). "The induction of aminoazo dye N-demethylase in nonhepatic tissues by 3-methylcholanthrene". ... Conney, AH; Gilman, AG (1963). "Puromycin inhibition of enzyme induction by 3-methylcholanthrene and phenobarbital". The ...
Murine respirovirus
"Sialylation of 3-methylcholanthrene-induced fibrosarcoma determines antitumor immune responses during immunoediting". Journal ...
George Klein (biologist)
In 1960 the Kleins published an important paper in Cancer Research, "Demonstration of Resistance against Methylcholanthrene- ... "Demonstration of Resistance against Methylcholanthrene-induced Sarcomas in the Primary Autochthonous Host". Cancer Research. 20 ... "Demonstration of Resistance against Methylcholanthrene-induced Sarcomas in the Primary Autochthonous Host". Cancer Research. 20 ...
CD4+ T cells and antitumor immunity
NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcoma. Int. Immunol. 13, pp. 459- ...
Unspecific monooxygenase
Evidence for many unique P-450-mediated monooxygenase activities reconstituted from 3-methylcholanthrene-treated C57BL/6N mouse ... "Differences in soluble P-450 hemoproteins from livers of rats treated with phenobarbital and 3-methylcholanthrene". Chem. Biol ...
Ilya B. Tsyrlov
... in vivo model for analysis of the induction of liver microsomal monooxygenases by sodium phenobarbital and 3-methylcholanthrene ...
Mycobacterium vanbaalenii
3-methylcholanthrene and benzopyrene. First isolated from an environmental source, not known to be pathogenic. Strain PYR-1 = ...
Polychlorinated biphenyl
... induced P450s catalyze oxygenation to the meta-para positions of PCBs while 3-methylcholanthrene (3MC)-induced P450s add ...
Hepatotoxin
... idiosyncratic Methapyrilene Methotrexate 3-methylcholanthrene. All penicillins - idiosyncratic Sulfonamide antibiotics - ...
Robert D. Schreiber
"Tumor development after 3-methylcholanthrene in immunologically deficient athymic-nude mice", Science 183:1534, 1974 Meraz, M.A ...
MCA
... manufactured by chlorinating acetic acid Methylcholanthrene, a carcinogen Methyl cyanoacrylate, an organic compound Metabolic ...
Ernest Kennaway
... and also discovered a series of other carcinogenic hydrocarbons including methylcholanthrene. In 1930, Kennaway and Izrael ...
Tumor microenvironment
In 1960, Klein and colleagues found that in mice, primary methylcholanthrene-induced sarcomas exhibited an antitumor immune ...
Aryl hydrocarbon receptor
3-methylcholanthrene, benzo[a]pyrene, benzanthracenes and benzoflavones). A range of synthetic ligands have been designed to ...
List of MeSH codes (D04)
... methylcholanthrene MeSH D04.615.149.700 - perylene MeSH D04.615.181.384 - dibenzocycloheptenes MeSH D04.615.181.384.100 - ...