"DrugBank: Methimazole (DB00763)". drugbank.ca. Retrieved 21 July 2015. "Methimazole Monograph for Professionals". Drugs.com. ... "Methimazole - Drug Usage Statistics". ClinCalc. Retrieved 11 April 2020. Fumarola, A; Di Fiore, A; Dainelli, M; Grani, G; ... October 2007). "Methimazole inhibits CXC chemokine ligand 10 secretion in human thyrocytes". J. Endocrinol. 195 (1): 145-55. ... "Methimazole Use During Pregnancy". Drugs.com. Retrieved 8 April 2019. World Health Organization (2019). World Health ...
The main antithyroid drugs are carbimazole (in the UK), methimazole (in the US), and propylthiouracil/PTU. A less common ... A randomized control trial testing single dose treatment for Graves' found methimazole achieved euthyroid state more ... "Efficacy of single daily dosage of methimazole vs. propylthiouracil in the induction of euthyroidism". Clin. Endocrinol. 54 (3 ... "Agranulocytosis with tonsillitis associated with methimazole therapy". Brazilian Journal of Otorhinolaryngology. 71 (3): 374- ...
A well-known FMO inhibitor is methimazole (MMI). The FMO catalytic cycle proceeds as follows: The cofactor NADPH binds to the ...
In a thyrotoxic crisis it is generally more effective than methimazole. Otherwise it is typically only used when methimazole, ... PTU is preferred over methimazole (which is also a class D) only in the first trimester of pregnancy and in women who may ... In the second and third trimester, this risk is diminished and methimazole is preferred to avoid the risk of liver ... This is in contrast to methimazole, which shares propylthiouracil's central mechanism, but not its peripheral one.) It is ...
Guo Z, Raeissi S, White RB, Stevens JC (March 1997). "Orphenadrine and methimazole inhibit multiple cytochrome P450 enzymes in ...
TPO is inhibited by the thioamide drugs, such as propylthiouracil and methimazole. In laboratory rats with insufficient iodine ...
The exact etiology of ACC is still unclear but intrauterine infection by varicella or herpes virus, drugs such as methimazole, ... It can also seen with exposure to methimazole and carbimazole in utero. This dermatological manifestation has been linked to ... "Aplasia cutis congenita and other anomalies associated with methimazole exposure during pregnancy". Pediatric Dermatology. 28 ( ...
Methimazole is available as an oral solution, a tablet, and compounded as a topical gel that is applied using a finger cot to ... Medical and dietary management using methimazole and Hill's y/d cat food will give hyperthyroid cats an average of 2 years ... Drugs used to help manage the symptoms of hyperthyroidism are methimazole and carbimazole. Drug therapy is the least expensive ... Medications such as beta blockers may control the symptoms, and anti-thyroid medications such as methimazole may temporarily ...
... methimazole, itopride, ketoconazole, tamoxifen and sulindac sulfide; and agrichemicals, such as organophosphates and carbamates ...
The main antithyroid drugs are carbimazole (in the UK), methimazole (in the US), and propylthiouracil/PTU. These drugs block ... Medications such as beta blockers may control some of the symptoms, and antithyroid medications such as methimazole may ... A randomized control trial testing single-dose treatment for Graves' found methimazole achieved euthyroid state more ... "Efficacy of single daily dosage of methimazole vs. propylthiouracil in the induction of euthyroidism". Clinical Endocrinology. ...
"Probing the substrate specificity of the ergothioneine transporter with methimazole, hercynine, and organic cations". ...
To form NaTm {Na+ HB(mt)3−), Methimazole and sodium borohydride are heated together. Coordination chemistry with ruthenium, ...
Members of the thioamide group include methimazole, carbimazole (converted in vivo to methimazole), and propylthiouracil. ...
Iodide was used to treat hyperthyroidism before antithyroid drugs such as propylthiouracil and methimazole were developed. ...
... is a pro-drug as after absorption it is converted to the active form, methimazole. Methimazole prevents thyroid ...
Propylthiouracil is preferred over methimazole due to its additional effects on reducing peripheral conversion of T4 to T3, ... Antithyroid drugs (propylthiouracil or methimazole) are used to reduce the synthesis and release of thyroid hormone. ... propylthiouracil or methimazole) to reduce synthesis and release of thyroid hormone. Temperature control and intravenous fluids ...
The main antithyroid drugs are carbimazole (in the UK), methimazole (in the US), and propylthiouracil/PTU. These drugs block ... A randomized control trial testing single-dose treatment for Graves' found methimazole achieved euthyroid state more ... and antithyroid medications such as methimazole may temporarily help people while other treatments are having effect.[1] ... "Efficacy of single daily dosage of methimazole vs. propylthiouracil in the induction of euthyroidism". Clinical Endocrinology. ...
... carbimazole and methimazole. Alternatively, radioactive iodine-131 can be used to destroy thyroid tissue: radioactive iodine is ...
"Extensive gingival necrosis and sequestration of the alveolar bone caused by methimazole-induced neutropenia and three-year ...
... carbimazole or methimazole, or rarely with Lugol's solution. Additionally, hyperthyroidism and thyroid tumors may be treated ...
It is easily prepared by the reaction of molten methimazole (1-methylimidazole-2-thione) with sodium borohydride, giving the ...
For this reason, sometimes patients are pre-treated with thyrostatic medications such as methimazole, and/or they are given ...
... is structurally similar to methimazole, which is used to inhibit thyroid hormone synthesis, and has been linked to ...
The anti-thyroid medication methimazole has been associated with the development of choanal atresia in rare cases if given ...
Methimazole is available as an oral solution, a tablet, and compounded as a topical gel that is applied using a finger cot to ... Medical and dietary management using methimazole and Hill's y/d cat food will give hyperthyroid cats an average of 2 years ... and methimazole (used in the US, Germany and Russia), and propylthiouracil. Thyrostatics are believed to work by inhibiting the ... and anti-thyroid medications such as methimazole may temporarily help people while other treatments are having effect.[1] ...
Medical therapy with anti-thyroid medications is the treatment of choice for hyperthyroidism in pregnancy.Methimazole and ... should be on PTU during the first trimester of pregnancy due to lower tetragenic effect and then be switched to methimazole ...
Medications such as propylthiouracil and methimazole are administered to block the release of thyroxine from the thyroid and to ...
... methimazole or propylthiouracil). This animal model has proven to be an extremely valuable tool for investigating the cross- ...
Toxic multinodular goiter can be treated with antithyroid medications such as propylthiouracil or methimazole, radioactive ...
However, interaction of disulfide bond in the insulin molecule with sulfhydryl group drugs such as methimazole, carbimazole, ...