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*  Mesangial cell
Mesangial cells can be categorised as either extraglomerular mesangial cells or intraglomerular mesangial cells, based on their ... B and mesangial cells have receptors for PDGF. This induces mesangial cells to attach to endothelial cells causing developing ... Mesangial cells are specialised cells in the kidney that make up the mesangium of the glomerulus. Together with the mesangial ... Damage to mesangial cells using Thy 1-1 antibody specific to mesangial cells causes the vasoconstriction of arterioles mediated ...
*  Intraglomerular mesangial cell
Intraglomerular mesangial cells have contractile activity. The initiation of contraction of mesangial cells is similar to that ... Intraglomerular mesangial cells aid neutrophils in removing other mesangial cells undergoing apoptosis, and other debris. ... Mesangium Extraglomerular mesangial cell Junqueira L.C., Carneiro J. in Kelley R.O. (2003). Basic histology, 10. izdaja. New ... Mesangial cells are of monocyte or smooth muscle origin, typically covering 30% of glomerular capillaries. They are both ...
*  Extraglomerular mesangial cell
Extraglomerular mesangial cells (also known as Lacis cells, Polkissen cells, or Goormaghtigh cells) are light-staining ... Extraglomerular mesangial cells are part of the juxtaglomerular apparatus, along with the macula densa cells of the distal ... mesangium intraglomerular mesangial cells Christensen, JA; Bohle, A; Mikeler, E; Taugner, R (January 1989). "Renin-positive ... The specific function of extraglomerular mesangial cells is not well understood, although it has been associated with the ...
*  SERPINB7
2003). "Mesangial cell-predominant gene, megsin". Nephrol. Dial. Transplant. 17 Suppl 9: 32-3. doi:10.1093/ndt/17.suppl_9.32. ...
*  Glomerulus (kidney)
Glomerular mesangial cells structurally support the tufts. Blood enters the capillaries of the glomerulus by a single arteriole ... There is two-way chemical cross talk among the mesangial cells, the capillaries, and the podocytes to fine-tune the GFR. Blood ... The space between the capillaries of a glomerulus is occupied by intraglomerular mesangial cells. They are not part of the ... The tuft is structurally supported by intraglomerular mesangial cells. The blood is filtered across the capillary walls of this ...
*  QSER1
A notable decrease in QSER1 expression has been noted in renal mesangial cells in response to treatment with 25 mM glucose. ... of QSER1 was also noted in mammary epithelial cells of immortalized cell lines than in mammary epithelial cells from cell lines ... This condition was studied as differential expression of genes involved in cell cycle regulation had been noted in these cells ... "High glucose-altered gene expression in mesangial cells. Actin-regulatory protein gene expression is triggered by oxidative ...
*  TGF beta 1
Schnaper HW, Hayashida T, Hubchak SC, Poncelet AC (2003). "TGF-beta signal transduction and mesangial cell fibrogenesis". Am. J ... Most immune cells (or leukocytes) secrete TGF-β1. Some T cells (e.g. regulatory T cells) release TGF-β1 to inhibit the actions ... It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell ... However, as with other cell types, TGF-β1 can also have the opposite effect on cells of myeloid origin. For example, TGF-β1 ...
*  Hemoglobin
... alveolar cells, and mesangial cells in the kidney. In these tissues, hemoglobin has a non-oxygen-carrying function as an ... Some nonerythroid cells (i.e., cells other than the red blood cell line) contain hemoglobin. In the brain, these include the A9 ... alveolar cells, and mesangial cells in the kidney. Historically, an association between the color of blood and rust occurs in ... The hemoglobin-derived iron in these cells is not the cause of the post-mortem darkness of these cells (origin of the Latin ...
*  Nephron
Podocytes, Endothelial cells, and Glomerular mesangial cell are present. Nephrology Urology Pocock, Gillian; Richards, ... It contains three components: the macula densa, juxtaglomerular cells, and extraglomerular mesangial cells.[citation needed] ... and the mesangial cells supporting these capillaries. These components function as the filtration unit and make up the renal ... Cells lining the tubule have numerous mitochondria to produce enough energy (ATP) for active transport to take place. Much of ...
*  Bacitracin
Weston, B.; Wahab, N.; Roberts, T.; Mason, R. (2001). "Bacitracin inhibits fibronectin matrix assembly by mesangial cells in ... We named this growth-antagonistic strain for the patient, "Tracy I." When cell-free filtrates of broth cultures of this ... These peptides disrupt gram positive bacteria by interfering with cell wall and peptidoglycan synthesis. Bacitracin is ... a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner ...
*  ITGA8
2004). "Role of alpha8 integrin in mesangial cell adhesion, migration, and proliferation". Kidney Int. 64 (1): 119-27. doi: ... 1999). "Alpha8 integrin in glomerular mesangial cells and in experimental glomerulonephritis". Kidney Int. 56 (4): 1468-80. doi ... a beta 1-associated alpha subunit expressed in smooth muscle cells". J Cell Sci. 108 (2): 537-44. PMID 7768999. "Entrez Gene: ... Littlewood Evans A, Müller U (2000). "Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in ...
*  KLF4
"Generation of induced pluripotent stem cells from human kidney mesangial cells". Journal of the American Society of Nephrology ... "Induction of pluripotent stem cells from adult human fibroblasts by defined factors". Cell. 131 (5): 861-72. doi:10.1016/j.cell ... "Induction of pluripotent stem cells from adult human fibroblasts by defined factors". Cell. 131 (5): 861-72. doi:10.1016/j.cell ... However, some studies have revealed that under certain conditions KLF4 may switch its role from pro-cell survival to pro-cell ...
*  AXL receptor tyrosine kinase
"Gas6 regulates mesangial cell proliferation through Axl in experimental glomerulonephritis". The American Journal of Pathology ... AXL is expressed on the tumor cells as well as adjacent immune cells including dendritic cells, macrophages, and NK cells. Axl ... "Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells". Cell Stem Cell. 18 (5): 591- ... AXL protein is expressed in normal tissues, particularly in bone marrow stroma and myeloid cells, and in tumour cells and ...
*  Mesangial proliferative glomerulonephritis
It is classified as type II lupus nephritis by the World Health Organization (WHO). Mesangial cells in the renal glomerulus use ... This normal process stimulates mesangial cell proliferation and matrix deposition. Therefore, during times of elevated ... one would expect to see an increased number of mesangial cells and matrix in the glomerulus. This is characteristic of ... Mesangial proliferative glomerulonephritis is a form of glomerulonephritis associated primarily with the mesangium. There is ...
*  Renal corpuscle
Endothelial cells, which have large fenestrae, are not covered by diaphragms. Mesangial cells are modified smooth muscle cells ... Mesangial cells also have phagocytic activity, removing proteins and other molecules trapped in the glomerular basement ... It consists of a glomerulus - a tuft of capillaries composed of endothelial cells, and a glomerular capsule known as Bowman's ... The lamina rara interna is adjacent to endothelial cells. This layer contains heparan sulfate, a negatively charged ...
*  TNS1
2004). "Tensin is potentially involved in extracellular matrix production in mesangial cells". Histochem. Cell Biol. 121 (3): ... doi:10.1016/j.cell.2006.09.026. PMID 17081983. Eto M, Kirkbride J, Elliott E, et al. (2007). "Association of the tensin N- ... The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the ... 1996). "p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL ...
*  Agkistrodon
Schlondorff D (October 1987). "The glomerular mesangial cell: an expanding role for a specialized pericyte". The FASEB Journal ... They cleave cytoskeleton filaments and DNA until the cell completely implodes. If this pathway can be activated in tumor cells ... If injected into mice, within 2 hours the venom begins a process known as mesangiolysis (the degeneration and death of cells ... Deinagkistrodon acutus snake venom contains a protein called ACTX-6. This protein was shown to induce apoptosis (cell death) in ...
*  ADAM15
2002). "The role of ADAM 15 in glomerular mesangial cell migration". J. Biol. Chem. 277 (37): 33683-9. doi:10.1074/jbc. ... Najy AJ, Day KC, Day ML (February 2008). "ADAM15 supports prostate cancer metastasis by modulating tumor cell-endothelial cell ... suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively ... Cell Res. 279 (2): 239-47. doi:10.1006/excr.2002.5606. PMID 12243749. Strausberg RL, Feingold EA, Grouse LH, et al. (2003). " ...
*  MST1
2002). "Macrophage-stimulating protein is produced by tubular cells and activates mesangial cells". J. Am. Soc. Nephrol. 13 (3 ... Cell. 5 (2): 257-71. doi:10.1016/S1534-5807(03)00201-6. PMID 12919677. Angeloni D, Danilkovitch-Miagkova A, Miagkov A, et al. ( ... "Regional localization of chromosome 3-specific DNA fragments by using a hybrid cell deletion mapping panel". Am J Hum Genet. 43 ...
*  FCGR3A
Morcos M, Hänsch GM, Schönermark M, Ellwanger S, Härle M, Heckl-Ostreicher B (December 1994). "Human glomerular mesangial cells ... CD45 and zeta and gamma chains on human natural killer cells". Immunology and Cell Biology. 72 (1): 87-96. doi:10.1038/icb. ... Le Coniat M, Kinet JP, Berger R (1990). "The human genes for the alpha and gamma subunits of the mast cell receptor for ... Cell type-specific expression of two genes that differ in single nucleotide substitutions". The Journal of Experimental ...
*  Myofibroblast
Pericytes and renal mesangial cells are some examples of modified myofibroblast-like cells. Myofibroblasts may interfere with ... Partial smooth muscle differentiation of a fibroblastic cell Activation of a stellate cell (e.g. hepatic Ito cells or ... A myofibroblast is a cell that is in between a fibroblast and a smooth muscle cell in phenotype. There are many possible ways ... of a smooth muscle cell. Direct myofibroblastic differentiation of a progenitor cell resident in a stromal tissue. Homing and ...
*  Zinc finger protein 236
Holmes, D. I.; Abdel Wahab, N; Mason, R. M. (1997). "Identification of glucose-regulated genes in human mesangial cells by mRNA ...
*  NT5E
Vlahović P, Stefanović V (1995). "Effect of dopamine on ecto-5'-nucleotidase expression in human glomerular mesangial cells". ... Airas L, Jalkanen S (September 1996). "CD73 mediates adhesion of B cells to follicular dendritic cells". Blood. 88 (5): 1755-64 ... Kirchhoff C, Hale G (March 1996). "Cell-to-cell transfer of glycosylphosphatidylinositol-anchored membrane proteins during ... on lymphocytes and endothelial cells". The Journal of Cell Biology. 136 (2): 421-31. doi:10.1083/jcb.136.2.421. PMC 2134816 . ...
*  Glomerulonephritis
At the same time, reactive changes, e.g. proliferation of mesangial cells,[which?] may result in a decrease in kidney blood ... The nephritic syndrome is characterised by blood in the urine (especially Red blood cell casts with dysmorphic red blood cells ... This is characterised by forms of glomerulonephritis in which the number of cells is not changed. These forms usually result in ... On microscopy, affected glomerules may show an increase in hyalin, a pink and homogenous material, fat cells, an increase in ...
*  PTX3
"The long pentraxin PTX3 is synthesized in IgA glomerulonephritis and activates mesangial cells". J. Immunol. 170 (3): 1466-72. ... Gershov D, Kim S, Brot N, Elkon KB (November 2000). "C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from ... In addition, preincubation of apoptotic cells with PTX3 enhances C1q binding and C3 deposition on the cell surface, suggesting ... Moreover, in the presence of dying cells, PTX3 restricts the cross presentation of antigens derived from dying cells. These ...
*  LECT2
Several cell types or tissues, e.g. osteoblasts, chondrocytes, cardiac tissue, gastrointestinal smooth muscle cells, and ... mesangial, glomerular, and/or vascular areas of the kidney and b) the identification of these deposits as containing mainly ... However, its expression in these cells is extremely low or undetectable even though these cells express very high levels of ... The protein was detected in and purified from cultures of Phytohaemagglutinin-activated human T-cell leukemia SKW-3 cells. ...