... required for cellular function but are unable to diffuse freely across a membrane enter through a membrane transport protein or ... Certain proteins and lipids rest only on one surface of the membrane and not the other. • Both the plasma membrane and internal ... For all cells, membrane fluidity is important for many reasons. It enables membrane proteins to diffuse rapidly in the plane of ... Integral proteins span the membranes with different domains on either side. Integral proteins hold strong association with the ...

Hicke L, Dunn R (2003). "Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins". Annual Review ... Vesicles also transport molecules directly back to the plasma membrane, but many molecules are transported in vesicles that ... Transmembrane proteins can be delivered to the perimeter membrane or the lumen of lysosomes. Transmembrane proteins destined ... and the iron transport protein transferrin. Internalization of these receptors from the plasma membrane occurs by receptor- ...

A carboxylate transporter is a membrane transport protein that transports carboxylate. They are responsible for the ... ISBN 1-4160-2328-3. Page 799 v t e (Transport proteins, All stub articles, Microbiology stubs). ... there are several kinds of carboxylate transporters in the apical membrane and the basolateral membrane. Na-monocarboxylate ...

... is a membrane transport protein associated with primary carnitine deficiency. This protein is involved in the active ... transporting one sodium ion with one molecule of carnitine. Organic cations transported by this protein include ... The SLC22A5 gene codes for a plasma integral membrane protein which functions as both an organic cation transporter and a ... The gene produces a 63 kDa protein composed of 557 amino acids. The protein has 12 putative transmembrane domains, with a long ...

2004). "Phylogeny as a guide to structure and function of membrane transport proteins". Mol Membr Biol. 21 (3): 171-181. doi: ... The membrane potential alters the conformation of the channel proteins, regulating their opening and closing. Cell membranes ... thus they must diffuse through the membrane through transmembrane protein channels. They have a crucial role in excitable cells ... which are located on the inner surface of the cell membrane and do not cross the membrane, and which are coassembled with the α ...

The Holin superfamily VI is a superfamily of integral membrane transport proteins. It is one of the seven different holin ... Portal: Biology v t e (Holins, Protein families, Protein superfamilies, All stub articles, Membrane protein stubs). ... In general, these proteins are thought to play a role in regulated cell death, although functionality varies between families ... These proteins appear to have one N-terminal transmembrane segment (TMS), followed by an amphipathic, weakly hydrophobic peak ...

The Holin superfamily VII is a superfamily of integral membrane transport proteins. It is one of the seven different holin ... Portal: Biology v t e (Holins, Protein superfamilies, All stub articles, Membrane protein stubs). ... In general, these proteins are thought to play a role in regulated cell death, although functionality varies between families ... includes proteins displaying 4 putative TMSs. Holin Lysin Transporter Classification Database "Holin Superfamily VII". ...

Protein families, Membrane proteins, Transmembrane proteins, Transmembrane transporters, Transport proteins, Integral membrane ... The KefC ancillary protein is YabF while the KefB ancillary protein is YheR. These ancillary proteins stimulate transport ... "Phylogeny as a guide to structure and function of membrane transport proteins". Molecular Membrane Biology. 21 (3): 171-81. doi ... Its transport function is not known. The GerN and GrmA proteins of Bacillus cereus and Bacillus megaterium, respectively, are ...

The Holin Superfamily III is a superfamily of integral membrane transport proteins. It is one of the seven different holin ... Portal: Biology v t e (Holins, Protein superfamilies, All stub articles, Membrane protein stubs). ... In general, these proteins are thought to play a role in regulated cell death, although functionality varies between families ... The average size of proteins in the entire superfamily is 114 aas with a standard deviation o 23 aas. Holin Lysin Transporter ...

The Holin superfamily V is a superfamily of integral membrane transport proteins. It is one of the seven different holin ... Portal: Biology v t e (Holins, Protein superfamilies, All stub articles, Membrane protein stubs). ... Proteins of this superfamily all appear to have 3 transmembrane segments (TMSs) and have average sizes of 97 and 101 amino acyl ... In general, these proteins are thought to play a role in regulated cell death, although functionality varies between families ...

"Phylogeny as a guide to structure and function of membrane transport proteins". Molecular Membrane Biology. 21 (3): 171-81. doi ... pathological and therapeutic implications of human membrane transport proteinsIntroduction". Pflügers Archiv: European Journal ... Family There are several APC proteins expressed in humans, and they are SLC proteins. There are 11 SLC families including APC ... Natural Resistance-Associated Macrophage Protein), CstA (Carbon starvation A protein), KUP (K+ Uptake Permease), BenE (Benzoate ...

Membrane proteins, Transmembrane proteins, Transmembrane transporters, Transport proteins, Integral membrane proteins, Protein ... "Phylogeny as a guide to structure and function of membrane transport proteins". Molecular Membrane Biology. 21 (3): 171-81. doi ... This transport process is dependent on several cytoplasmic phosphoryl transfer proteins - Enzyme I (I), HPr, Enzyme IIA (IIA), ... "Phylogenetic characterization of transport protein superfamilies: superiority of SuperfamilyTree programs over those based on ...

Membrane proteins, Transmembrane proteins, Transmembrane transporters, Transport proteins, Integral membrane proteins, Protein ... "Phylogeny as a guide to structure and function of membrane transport proteins". Molecular Membrane Biology. 21 (3): 171-181. ... The cation:proton antiporter (CPA) superfamily is a superfamily of transport proteins named after one of its constituent ... 2011). "Phylogenetic Characterization of Transport Protein Superfamilies: Superiority of SuperfamilyTree Programs over Those ...

Membrane proteins, Transmembrane proteins, Transmembrane transporters, Transport proteins, Integral membrane proteins, Protein ... "Phylogeny as a guide to structure and function of membrane transport proteins". Molecular Membrane Biology 21 (3): 171-181.doi: ... This transport process is dependent on several cytoplasmic phosphoryl transfer proteins - Enzyme I (I), HPr, Enzyme IIA (IIA), ... "Phylogenetic Characterization of Transport Protein Superfamilies: Superiority of SuperfamilyTree Programs over Those Based on ...

It is able to transport proteins and DNA across the cell membrane. The type IV secretion system is just one of many bacterial ... A single protein, VirB10 is integral in both the inner and outer membranes. It inserts into the outer membrane using an α- ... Either VirB6 or VirB8 is believed to form the inner membrane pore, as they are integral proteins on the inner membrane and have ... The type IV secretion system is a protein complex found in prokaryotes used to transport DNA, proteins, or effector molecules ...

Peripheral membrane proteins, Protein complexes, Protein families, Molecular evolution, Vesicular transport proteins). ... AP2 adaptor complex Vesicular transport adaptor protein Umasankar PK, Ma L, Thieman JR, Jha A, Doray B, Watkins SC, Traub LM ( ... The muniscin protein family was initially defined in 2009 as proteins having 2 homologous domains that are involved in clathrin ... The muniscins are early arriving proteins involved in CME. FCHO proteins are required for CME, but do not appear to be required ...

The Holin superfamily IV is a superfamily of integral membrane transport proteins. It is one of the seven different holin ... Portal: Biology v t e (Holins, Protein superfamilies, All stub articles, Membrane protein stubs). ... The extra TMS in these proteins is at their N-termini. Holin Lysin Transporter Classification Database "Holin Superfamily IV". ... which has members larger than the other proteins in this superfamily. All members of families 10 and 19 and many members of ...

Protein families, Membrane proteins, Transmembrane proteins, Transmembrane transporters, Transport proteins, Integral membrane ... "Phylogeny as a guide to structure and function of membrane transport proteins". Molecular Membrane Biology. 21 (3): 171-81. doi ... The bacterial proteins have 520-550 amino acyl residues (aas) while eukaryotic proteins are generally larger, varying in size ... "Phylogenetic characterization of novel transport protein families revealed by genome analyses". Biochimica et Biophysica Acta ( ...

Protein families, Membrane proteins, Transmembrane proteins, Transmembrane transporters, Transport proteins, Integral membrane ... "Phylogeny as a guide to structure and function of membrane transport proteins". Molecular Membrane Biology. 21 (3): 171-181. ... "Topological predictions for integral membrane permeases of the phosphoenolpyruvate:sugar phosphotransferase system". Journal of ...

Wagegg, W; Braun, V (January 1981). "Ferric citrate transport in Escherichia coli requires outer membrane receptor protein fecA ... This change was partly the result of a mutation that changed the expression of a gene for a penicillin-binding protein, which ... The duplicated segment contained the gene citT for the citrate transporter protein used in anaerobic growth on citrate. The ... Philippe, Nadège; Pelosi, Ludovic; Lenski, Richard E.; Schneider, Dominique (2008). "Evolution of Penicillin-Binding Protein 2 ...

Protein families, Membrane proteins, Transmembrane proteins, Transmembrane transporters, Transport proteins, Integral membrane ... APC Superfamily Transporter Classification Database Membrane transport protein Saier MH (August 2000). "Families of ... The Amino Acid-Polyamine-Organocation (APC) Family (TC# 2.A.3) of transport proteins includes members that function as solute: ... The larger eukaryotic and archaeal proteins possess N- and C-terminal hydrophilic extensions. Some animal proteins, for example ...

This pathway is referred to as retrograde transport. Before the COP I protein can coat vesicles on the Golgi membrane, it must ... The coatomer is a protein complex that coats membrane-bound transport vesicles. Two types of coatomers are known: COPI ( ... Membrane bound Sar1 attracts the Sec23-Sec24 protein heterodimer to the ER membrane. Sar1 directly binds to Sec23 while Sec24 ... Once Sar1 interacts with the ER membrane, a membrane protein called Sec12 acts a guanine nucleotide exchange factor and ...

"Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells". Cell. 175 (2): 514-529. ... These proteins are mammalian representatives of the yeast lipid transfer proteins anchored at a membrane contact site (LAM) ... When the plasma membrane contains high levels of cholesterol, GRAMD1a like GRAMD1b and GRAMD1c moves to sites of contact ... GRAM domain containing 1A also known as Aster-A is a protein that is encoded by the GRAMD1A gene. It contains a transmembrane ...

Transport proteins, Transmembrane transporters, All stub articles, Membrane protein stubs). ... A chloride hydroxyl exchanger is a purported membrane transport protein responsible for the exchange of chloride and hydroxyl ... However, little is known about the protein responsible for this action. "Functional identity of a purified proximal tubule ... anion exchanger protein: Mediation of chloride/formate and chloride/bicarbonate exchange". v t e ( ...

"Aster proteins facilitate nonvesicular plasma membrane to ER cholesterol transport in mammalian cells". Cell. 175 (2): 514-529. ... Analysis of the crystal structure of unbound and bound forms of VASt domains in lipid transfer proteins anchored at a membrane ... Like LAM proteins, GRAMD1 proteins preferentially transfer sterols. Khafif M, Cottret L, Balagué C, Raffaele S (2014). " ... These sterol transfer proteins together with GRAMD2A and GRAMD2B are LAM family proteins, although the latter two lack the VASt ...

Membrane proteins, Transmembrane proteins, Transmembrane transporters, Transport proteins, Integral membrane proteins). ... The Na+ Transporting Mrp Superfamily is a superfamily of integral membrane transport proteins. It includes the TC families: 2.A ... As of this edit, this article uses content from "Na+ Transporting Mrp Superfamily", which is licensed in a way that permits ... These homologous subunits may catalyze Na+/K+ and/or H+ transport. Transporter Classification Database Zickermann, Volker; ...

The protein belongs to the solute carrier 26 family of membrane transport proteins. More than 20 mutations in the gene are ... Kere J, Lohi H, Höglund P (January 1999). "Genetic Disorders of Membrane Transport III. Congenital chloride diarrhea". The ... "The solute carrier 26 family of proteins in epithelial ion transport". Physiology. 23 (2): 104-14. doi:10.1152/physiol. ... a gene that encodes a membrane protein of intestinal cells. ...

... s are a subcategory of membrane transport proteins (transporters) that couple the favorable movement of one ... Articles with short description, Short description matches Wikidata, Integral membrane proteins, Transport phenomena). ... "Proteins for Transport of Water and Mineral Nutrients across the Membranes of Plant Cells". The Plant Cell. 11 (4): 661-675. ... anion transport protein. This cotransporter is an important integral protein in mammalian erythrocytes and moves chloride ion ...

Transport of PEP across the mitochondrial membrane is accomplished by dedicated transport proteins; however no such proteins ... it triggers phosphorylation of enzymes and regulatory proteins by Protein Kinase A (a cyclic AMP regulated kinase) resulting in ... Lactate is transported back to the liver where it is converted into pyruvate by the Cori cycle using the enzyme lactate ... In the liver, the FOX protein FOXO6 normally promotes gluconeogenesis in the fasted state, but insulin blocks FOXO6 upon ...

4 October 2018). "Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells". Cell ... Homologs of GramD proteins (Lam/Ltc proteins) are found in yeast. The protein is expressed in the liver and testes. When the ... GRAM domain containing 1C also known as Aster-C is a cholesterol transport protein that is encoded by the GRAMD1C gene. It ... GRAMD1 proteins then facilitate the transport of cholesterol into the endoplasmic reticulum. Reduction of GRAMD1B and GRAMD1C ...