Kalkavan, Halime; Green, Douglas R. (2018). "MOMP, cell suicide as a BCL-2 family business". Cell Death & Differentiation. 25 ( ... During MOMP, it takes about five minutes for all mitochondrial membranes within a cell to permeabilize. MOMP has been referred ... Mitochondrial outer membrane permeabilization (MOMP), also known as the mitochondrial outer membrane permeability, is one of ... mitochondrial membranes become permeable in most, but not all, the cell's mitochondria. In minority MOMP, only a few ...

Regulation of cell differentiation, proliferation, division and movement. Translocation of proteins through membranes. ... GEF activity is stimulated by cell surface receptors in response to signals outside the cell (for heterotrimeric G proteins, ... regulatory GEFs for many other small GTPases are activated in response to intrinsic cell signals, not cell surface (external) ... In unstimulated cells, heterotrimeric G proteins are assembled as the GDP bound, inactive trimer (Gα-GDP-Gβγ complex). Upon ...

... is expressed close to the cancer cells in vivo, forming basement membrane like structures on the cancer cell ... It aids in cell adhesion, migration, survival, expansion, and differentiation. To begin, this type of collagen is synthesized ... 1996). "Type IV collagen in sponges, the missing link in basement membrane ubiquity". Biology of the Cell. 88 (1-2): 37-44. doi ... The interaction between type IV collagen produced by the cancer cell, and integrins on the surface of the cancer cells, are ...

... proteins have been found to accelerate differentiation of endothelial cells. The most notable examples of ... "Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like ... Fractones may be a type of basement membrane, serving as a niche for stem cells. Some diseases result from a poorly functioning ... 2005). Basement membranes: cell and molecular biology. Gulf Professional Publishing. ISBN 978-0-12-153356-4. (CS1: long volume ...

CLIP also can affect the differentiation of T cells. MHC II + CLIP complexes are upregulated on maturing dendritic cells, which ... MHC II with bound antigen is then transported to the plasma membrane for presentation. ... cells. Th cells can polarize into Th1 or Th2 effector cells depending on the presence of cytokines. High expression of CLIP ... This occurs in most cells expressing MHC II-however, in B cells, HLA-DO functions as the accessory protein. Both HLA-DM and HLA ...

Interbilayer Forces in Membrane Fusion Fusion mechanism Lipid bilayer fusion Cell-cell fusogens CAF-1 List of human cell types ... fat cells, and types of bone cells Epithelial stem cells (progenitor cells) that give rise to the various types of skin cells ... Cell differentiation is thus a transition of a cell from one cell type to another and it involves a switch from one pattern of ... During terminal differentiation, a precursor cell formerly capable of cell division permanently leaves the cell cycle, ...

... is released with perforin which inserts into a target cell's plasma membrane forming a pore. Perforin has a radius ... Cullen SP, Brunet M, Martin SJ (April 2010). "Granzymes in cancer and immunity". Cell Death and Differentiation. 17 (4): 616-23 ... Granzyme B is secreted by regulatory T cells (tregs) to kill CD4+ T cells that have not been exposed to host cells that are ... NK cells) and cytotoxic T cells. It is secreted by these cells along with the pore forming protein perforin to mediate ...

"A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation". Nat. Genet. 11 ( ... The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is ... The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. ... "Pancreatic islet cells express a family of inwardly rectifying K+ channel subunits which interact to form G-protein-activated ...

"Constitutive overexpression of the integral membrane protein Itm2A enhances myogenic differentiation of C2C12 cells". Cell Biol ... The protein encoded by this gene is involved in osteo- and chondrogenic cellular differentiation (the cells which are ... ITM2A is also involved in activation of T-cells in the immune system and in myocyte differentiation. GRCh38: Ensembl release 89 ... "Entrez Gene: ITM2A integral membrane protein 2A". Mao M, Fu G, Wu JS, Zhang QH, Zhou J, Kan LX, Huang QH, He KL, Gu BW, Han ZG ...

"A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation". Nature Genetics ... In non-excitable cells, the resting potential across the plasma membrane (Vmem) of individual cells propagate across distances ... "Asymmetries in H+/K+-ATPase and cell membrane potentials comprise a very early step in left-right patterning". Cell. 111 (1): ... The inside/outside discontinuity at the cell surface enabled by a lipid bilayer membrane (capacitor) is at the core of ...

"A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation". Nature Genetics ... Cox, D. R.; Burmeister, M.; Price, E. R.; Kim, S.; Myers, R. M. (1990-10-12). "Radiation hybrid mapping: a somatic cell genetic ... a method that uses high-energy x-rays to fragment human chromosomes that were recovered in somatic cell hybrids and then used ...

The cell signalling involved in the stimulation of the A2B receptor directs the route of differentiation to osteoblast, rather ... This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts ... Carroll SH, Ravid K (2013). "Differentiation of mesenchymal stem cells to osteoblasts and chondrocytes: a focus on adenosine ... Similarly to A2A receptor, the A2B receptor promotes osteoblast differentiation. The osteoblast cell is derived from the ...

... which are major components of HDL and cell membranes. The fact that apoD may bind such a large variety of ligands strongly ... which is involved in cellular differentiation; and sphingomyelin and sphingolipids, ... APOD is an androgen up-regulated gene in normal scrotal fibroblast cells in comparison to labia majora cells in females with ... Studies on several cell types have shown that ApoD expression can be induced by several stressing situations such as growth ...

2005). "Regulation of a novel cell differentiation-associated gene, JWA during oxidative damage in K562 and MCF-7 cells". J. ... The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated ... 2004). "[Effect of differentiation inducer and heat stress on the expression of JWA protein and Hsp70 of K562 cells]". Zhonghua ... 2006). "JWA, a novel signaling molecule, involved in all-trans retinoic acid induced differentiation of HL-60 cells". J. Biomed ...

Schwann cells create the myelin sheath, by wrapping its plasma membrane around the axon. Neurons, Schwann cells, and ... Schwann cells and neurons exchange molecular signals by gap junctions that regulate survival and differentiation.[citation ... The mutation can appear in GJB1 coding for connexin 32, a gap junction protein expressed in Schwann cells. Because this protein ... The myelin sheath allows nerve cells to conduct signals faster. When the myelin sheath is damaged, nerve signals are slower, ...

... cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM. The animal extracellular matrix ... Hyaluronic acid is found on the inner surface of the cell membrane and is translocated out of the cell during biosynthesis. ... ECM elasticity can direct cellular differentiation, the process by which a cell changes from one cell type to another. In ... Plant cells are tessellated to form tissues. The cell wall is the relatively rigid structure surrounding the plant cell. The ...

By choosing appropriate antibodies, the differentiation of leukemic cells can be accurately determined. The labelled cells are ... It involves the labelling of white blood cells with antibodies directed against surface proteins on their membrane. ... The whole procedure can be performed on cells from the blood, bone marrow or spinal fluid in a matter of a few hours.[citation ... This can be done on tissue section (fresh or fixed tissue), cell suspension, etc. An example is the detection of tumor markers ...

LEP-R has also been designated as CD295 (cluster of differentiation 295). Its location is the cell membrane, and it has ... regulation of energy metabolism and body weight depends on interactions of the receptor with gangliosides in the cell membrane ... Like other cytokine receptors, Leptin receptor protein has three different regions: i) extracellular, ii) trans-membrane, and ... December 1995). "Identification and expression cloning of a leptin receptor, OB-R". Cell. 83 (7): 1263-71. doi:10.1016/0092- ...

Cluster of Differentiation 2), CD4, CD80, and CD86; in myelin membrane adhesion molecules; in junctional adhesion molecules ( ... V-set domains are found in diverse protein families, including immunoglobulin light and heavy chains; in several T-cell ... IPR003596 T-cell surface antigen CD2 InterPro: IPR013285 ACAM; ACAN; ADAMTSL1; AGC1; AMICA1; BCAM; BCAN; BGP; BGPc; BT3.3; ... JAM); in tyrosine-protein kinase receptors; and in the programmed cell death protein 1 (PD1). Immunoglobulin V-set, subgroup ...

2001). "Human sperm membrane protein (hSMP-1): a developmental testis-specific component during germ cell differentiation". ... 2004). "Sperm membrane protein (hSMP-1) and RanBPM complex in the microtubule-organizing centre". J. Mol. Med. 82 (6): 383-8. ... This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region ... Liu QY, Wang LF, Miao SY, Catterall JF (Oct 1996). "Expression and characterization of a novel human sperm membrane protein". ...

FcεRII has multiple functions as a membrane-bound or soluble receptor; it controls B cell growth and differentiation and blocks ... CD4+ T cells (mature Th cells) provide help to B cells that produce antibodies. Several subsets of activated effector CD4+ T ... until the cell membrane of the phagocyte completely encloses the pathogen. The Fc receptor on NK cells recognize IgG that is ... B cells). They allow these cells to bind to antibodies that are attached to the surface of microbes or microbe infected cells, ...

... is widely-expressed and membrane-associated in cultured cell lines". FEBS Lett. 313 (1): 19-22. doi:10.1016/0014-5793(92)81174- ... In the human fetus during muscle differentiation, utrophin is found at the sarcolemma. It disappears when the fetus begins to ... "Localization of utrophin and aciculin at sites of cell-matrix and cell-cell adhesion in cultured cells". Exp. Cell Res. 221 (1 ... In normal muscle cells, utrophin is located at the neuromuscular synapse and myotendinous junctions. It is necessary for normal ...

"The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymis". Genes ... The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function ... Cell. 131 (6): 1190-203. doi:10.1016/j.cell.2007.11.025. PMID 18083107. S2CID 2316452. Takeuchi K, Soda M, Togashi Y, Suzuki R ... Cell. 131 (6): 1190-203. doi:10.1016/j.cell.2007.11.025. PMID 18083107. S2CID 2316452. Bergethon K, Shaw AT, Ou SH, Katayama R ...

... preferentially bound membrane-associated heterodimeric RGMc and was able to interact on cells only with wild-type RGMc and G92V ... RGMc/HJV, is transcriptionally regulated during muscle differentiation. Two classes of GPI-anchored and glycosylated HJV ... There appears to be two potential soluble isoforms and two membrane-associated isoforms. The predominant membrane-associated ... J. Physiol., Cell Physiol. 294 (4): C994-C1003. doi:10.1152/ajpcell.00563.2007. PMID 18287331. S2CID 32158124. Yang, Fan; West ...

Together the LNR and HD compose the negative regulatory region adjacent to the cell membrane and help prevent signaling in the ... There is evidence that activated Notch 1 and Notch 3 promote differentiation of progenitor cells into astroglia. Notch 1, then ... the role of cell-cell interactions in establishing separate identities for equivalent cells". Cell. 68 (2): 271-81. doi:10.1016 ... Later studies in early Drosophila neurogenesis provided some of the first indications of Notch's roll in cell-cell signaling, ...

... a membrane-associated protein that belongs to a family of proteins involved in stem cell differentiation". Molecular Biology of ... Collins FS, Rossant J, Wurst W (Jan 2007). "A mouse for all reasons". Cell. 128 (1): 9-13. doi:10.1016/j.cell.2006.12.018. PMID ... Chu CY, Rana TM (Jul 2006). "Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54". PLOS ... Nature Cell Biology. 7 (6): 633-6. doi:10.1038/ncb1265. PMID 15908945. S2CID 6085169. Liu J, Valencia-Sanchez MA, Hannon GJ, ...

There is evidence that activated Notch 1 and Notch 3 promote differentiation of progenitor cells into astroglia. Notch 1, when ... This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development. A deficiency ... Cell. Biol. 20 (7): 2400-10. doi:10.1128/mcb.20.7.2400-2410.2000. PMC 85419. PMID 10713164. Chastagner P, Israël A, Brou C ( ... Cell. Biol. 22 (21): 7688-700. doi:10.1128/mcb.22.21.7688-7700.2002. PMC 135662. PMID 12370315. Blokzijl A, Dahlqvist C, ...

... it was determined that stem cells from the amniotic membrane also have multipotent potential. AS their differentiation into ... Amniotic stem cells are the mixture of stem cells that can be obtained from the amniotic fluid as well as the amniotic membrane ... 2007). "Renal differentiation of amniotic fluid stem cells". Cell Proliferation. 40 (6): 936-948. doi:10.1111/j.1365-2184.2007. ... There is some debate whether c-Kit is a suitable marker to distinguish amniotic stem cells from other cell types because cells ...

Astral microtubules are those extending out of the centrosome toward the cell cortex. They can connect to the plasma membrane ... These deposits are determined via polarity cues, growth and differentiation factors, or adhesion contacts.[citation needed] ... They can be found in a variety of cells which include smooth muscle cells, fibroblasts, and white blood cells. Type 4 ... They will help to assemble an orthogonal network in these cells in the nuclear membrane. Type 6 intermediate filaments are ...

Once the granulosa cells have fully surrounded the remaining nuclei, a basement membrane is laid down and completely ... These spermatids then undergo differentiation into mature sperm. In these developing male germ cells, they undergo incomplete ... Male germ-line stem cells divide asymmetrically to give one stem cell and a spermatogonia cell (unspecialised male germ cell) ... Germ cell nest breakdown involves the degeneration of many germ cell nuclei and the invasion of pre-granulosa cells into the ...

SLC45A2 is also a melanocyte differentiation antigen that is expressed in a high percentage of melanoma cell lines. A similar ... Membrane-associated transporter protein (MATP), also known as solute carrier family 45 member 2 (SLC45A2) or melanoma antigen ... In melanocytic cell types, the SLC45A2 gene is regulated by microphthalmia-associated transcription factor. SLC45A2 has been ... 2015). "Membrane-Associated Transporter Protein (MATP) Regulates Melanosomal pH and Influences Tyrosinase Activity". PLOS ONE. ...