*  Melphalan
... Prescribing Information: Alkeran Melphalan Patient Information: MedlinePlus Melphalan Material Safety Data Sheet ( ... October 2007). "Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous ... Otherwise known as L-phenylalanine mustard, or L-PAM, melphalan is a phenylalanine derivative of mechlorethamine. Melphalan ... an experimental prodrug of melphalan "Melphalan". National Cancer Institute. Retrieved 4 August 2014. Facon T, Mary JY, Hulin C ...
*  DMOZ - Health: Pharmacy: Drugs and Medications: M: Melphalan
Melphalan is used in the treatment of cancer. ... "Health ... Melphalan" search on: AOL - Ask - Bing - DuckDuckGo ...
*  Cannabis in Iowa
Melphalan, Alkeran, and Leukeran). She has spoken out to legislators in an effort to help others. Introduced by a committee, ... In 1980 research for cancer, Melphalan chemotherapy, and marijuana was conducted at the University of Iowa Hospital. One of the ...
*  Alkylating antineoplastic agent
Examples include melphalan and chlorambucil. The following three groups are almost always considered "classical". Nitrogen ... Uramustine or uracil mustard Melphalan Chlorambucil Ifosfamide Bendamustine Nitrosoureas Carmustine Lomustine Streptozocin ...
*  Buthionine sulfoximine
Defty, CL; Marsden, JR (2012). "Melphalan in regional chemotherapy for locally recurrent metastatic melanoma". Current topics ...
*  Spectrum Pharmaceuticals
Evomela (melphalan) is an alkalyating drug for multiple myeloma. A number of drugs are currently investigated in clinical ...
*  Chemotherapy
Most chemotherapy is delivered intravenously, although a number of agents can be administered orally (e.g., melphalan, busulfan ... Dexamethasone along with either bortezomib or melphalan is commonly used as a treatment for AL amyloidosis. Recently, ... Nitrogen mustards include mechlorethamine, cyclophosphamide, melphalan, chlorambucil, ifosfamide and busulfan. Nitrosoureas ... melphalan) including CDDP could be reversed at least partially by the addition of heat. Chemotherapy is used in veterinary ...
*  Chromosome abnormality
Melphalan is a bifunctional alkylating agent frequently used in chemotherapy. Meiotic inter-strand DNA damages caused by ... melphalan can escape paternal repair and cause chromosomal aberrations in the zygote by maternal misrepair. Thus both pre- and ...
*  Melflufen
Substantial clinical experience has been accumulated about melphalan since then. Numerous derivatives of melphalan, designed to ... Compared to melphalan, melflufen exhibits significantly higher in vitro and in vivo activity in several models of human cancer ... Melflufen (melphalan flufenamide, previously designated J1) is an anticancer drug under development by Oncopeptides AB. It is a ... Chemically, the drug is best described as the ethyl ester of a dipeptide consisting of melphalan and the amino acid derivative ...
*  Multiple myeloma
Treatment with bortezomib, melphalan, and prednisone had an estimated overall survival of 83% at 30 months, lenalidomide plus ... 2008). "Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma". N. Engl. J. Med. 359 (9): 906-917 ... For these patients, the standard of care has been chemotherapy with melphalan and prednisone. Recent studies among this ... such as melphalan, cyclophosphamide, thalidomide or dexamethasone, alone or in combination), and a second autologous stem cell ...
*  Millennium Pharmaceuticals
"VELCADE as Initial Standard Therapy in multiple myeloma: Assessment with melphalan and prednisone". Millennium Corporate ...
*  Juvenile myelomonocytic leukemia
The EWOG-MDS study also involves cyclophosphamide and melphalan in its conditioning regimen. Graft versus leukemia: Graft ...
*  Sporadic late onset nemaline myopathy
Improvement has also been noted with autologous stem cell transplantation, and chemotherapy with melphalan. Chahin N, Selcen D ...
*  Specialty drugs in the United States
"Melphalan granted FDA Orphan Drug Designation for treatment of cholangiocarcinoma", News-Medical.Net, 20 July 2015, retrieved 6 ... NASDAQ: DCTH) a specialty pharmaceutical and medical device company manufactures melphalan. By 2011 the oral medications for ... melphalan (trade name Alkeran), busulfan, capecitabine). Delcath Systems, Inc. ( ...
*  Development of analogs of thalidomide
EMA has also approved it to treat MM in combination with prednisone and/or melphalan. Orphan indications by the FDA include ...
*  Light chain deposition disease
High-dose melphalan in conjunction with autologous stem cell transplantation has been used in some patients. A regimen of ...
*  Amyloidosis
Treatment with high dose melphalan, a chemotherapy agent, followed by stem cell transplantation has showed promise in early ... Chemotherapy and steroids, with melphalan plus dexamethasone, is mainstay treatment in AL people not eligible for transplant. ...
*  Fertility preservation
... melphalan, chlorambucil and chlormethine. Drugs with medium risk include doxorubicin and platinum analogs such as cisplatin and ...
*  CFU-GEMM
... with neutrophil and platelet recovery in patients receiving autologous marrow transplantation after high-dose melphalan ...
*  POEMS syndrome
Hematological response rates to the dexamethasone/melphalan regimens have been reported to be in the 80% range with ... a corticosteroid such as dexamethasone plus an alkylating agents such as melphalan. Dosage regimens are selected on the basis ... neurological response rates approaching 100%. Patients successfully treated with the high-dose dexamethasone/melphalan regimen ...
*  Female infertility
... melphalan, chlorambucil and chlormethine. Drugs with medium risk include doxorubicin and platinum analogs such as cisplatin and ...
*  SLC7A5
... polymorphisms in the amino acid transporters LAT1 and LAT2 in relation to the pharmacokinetics and side effects of melphalan". ...
*  Aspen Pharmacare
In France 3 people died after being given cyclophosphamide, an alternative drug to Aspen's melphalan which had gone up in price ...
*  Papular mucinosis
It has been reported that clearance of lesions can be done with melphalan and cyclophosphamide alone or in combination with ...
*  Carmustine
... usually with Fludarabine and Melphalan, was coined by oncologists at the University of Texas MD Anderson Cancer Center. In the ...