Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... 1997). "Matrix metalloproteinases, tumor necrosis factor and multiple sclerosis: an overview". J. Neuroimmunol. 72 (2): 155-61 ... Neutrophil collagenase, also known as matrix metalloproteinase-8 (MMP-8) or PMNL collagenase (MNL-CL), is a collagen cleaving ... 1996). "Chondrocyte matrix metalloproteinase-8. Human articular chondrocytes express neutrophil collagenase". J. Biol. Chem. ...
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... Lee JM, Yin K, Hsin I, Chen S, Fryer JD, Holtzman DM, Hsu CY, Xu J (March 2005). "Matrix metalloproteinase-9 in cerebral- ... Li M, Yang G, Xie B, Babu K, Huang C (February 2014). "Changes in matrix metalloproteinase-9 levels during progression of ... Ramos-DeSimone N, Hahn-Dantona E, Sipley J, Nagase H, French DL, Quigley JP (May 1999). "Activation of matrix metalloproteinase ...
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... Nguyen Q, Murphy G, Hughes CE, Mort JS, Roughley PJ (October 1993). "Matrix metalloproteinases cleave at two distinct sites on ... Conca W, Willmroth F (June 1994). "Human T lymphocytes express a member of the Matrix Metalloproteinase gene family". Arthritis ... Lichtinghagen R, Helmbrecht T, Arndt B, Böker KH (February 1995). "Expression pattern of matrix metalloproteinases in human ...
Matrix metalloproteinase-14 is an enzyme that in humans is encoded by the MMP14 gene. Proteins of the matrix metalloproteinase ... Matrix metalloproteinase ARK5 GRCh38: Ensembl release 89: ENSG00000157227 - Ensembl, May 2017 GRCm38: Ensembl release 89: ... Nagase H, Woessner JF (1999). "Matrix metalloproteinases". J. Biol. Chem. 274 (31): 21491-4. doi:10.1074/jbc.274.31.21491. PMID ... membrane type 1-matrix metalloproteinase 1 (MT1-MMP)". J. Biol. Chem. 273 (2): 1216-22. doi:10.1074/jbc.273.2.1216. PMID ...
Matrix metalloproteinase-25 is an enzyme that in humans is encoded by the MMP25 gene. Proteins of the matrix metalloproteinase ... "Entrez Gene: MMP25 matrix metallopeptidase 25". Nagase H, Woessner JF (1999). "Matrix metalloproteinases". J. Biol. Chem. 274 ( ... 1996). "The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and ... 2000). "Membrane-type 6 matrix metalloproteinase (MT6-MMP, MMP-25) is the second glycosyl-phosphatidyl inositol (GPI)-anchored ...
doi:10.1007/s10555-006-7894-9. Hua, H.; Li, M.; Luo, T; Yin, Y.; Jiang, Y (2011). "Matrix Metalloproteinases in Tumorigenesis: ... doi:10.1111/j.1747-0285.2011.01148.x. Brown, P. D. (1997). "Matrix metalloproteinase inhibitors in the treatment of cancer". ... Metalloprotease inhibitors are cellular inhibitors of the Matrix metalloproteinases (MMPs). MMPs belong to a family of zinc- ... Matrix metalloproteinase MMP inhibitors Collagen Cancer Periodontitis Arthritis Rheumatoid arthritis Osteoarthritis ...
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix proteins and during ... The mechanism for MMP-3 is a variation on a larger theme seen in all matrix metalloproteinases. In the active site, a water ... Stromelysin-1 also known as matrix metalloproteinase-3 (MMP-3) is an enzyme that in humans is encoded by the MMP3 gene. The ... Lee JY, Choi HY, Ahn HJ, Ju BG, Yune TY (Nov 2014). "Matrix metalloproteinase-3 promotes early blood-spinal cord barrier ...
Matrix metalloproteinase-16 is an enzyme that in humans is encoded by the MMP16 gene. Proteins of the matrix metalloproteinase ... "Entrez Gene: MMP16 matrix metallopeptidase 16 (membrane-inserted)". Nagase H, Woessner JF (1999). "Matrix metalloproteinases". ... Mattei MG, Roeckel N, Olsen BR, Apte SS (1997). "Genes of the membrane-type matrix metalloproteinase (MT-MMP) gene family, ... Jung M, Römer A, Keyszer G (2003). "mRNA expression of the five membrane-type matrix metalloproteinases MT1-MT5 in human ...
Matrix metalloproteinase-19 (MMP-19) also known as matrix metalloproteinase RASI is an enzyme that in humans is encoded by the ... Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... 2000). "Matrix metalloproteinases 19 and 20 cleave aggrecan and cartilage oligomeric matrix protein (COMP)". FEBS Lett. 478 (1- ... 2002). "Matrix metalloproteinase-19 is expressed in myeloid cells in an adhesion-dependent manner and associates with the cell ...
Matrix metalloproteinase-20 (MMP-20) also known as enamel metalloproteinase or enamelysin is an enzyme that in humans is ... Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... 2000). "Matrix metalloproteinases 19 and 20 cleave aggrecan and cartilage oligomeric matrix protein (COMP)". FEBS Lett. 478 (1- ... Nagase H, Woessner JF (1999). "Matrix metalloproteinases". J. Biol. Chem. 274 (31): 21491-21494. doi:10.1074/jbc.274.31.21491. ...
Bein K, Simons M (Oct 2000). "Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of ... matrix metalloproteinase, thrombin, cathepsin, and elastase. Thrombospondin-1 binds to the reelin receptors, ApoER2 and VLDLR, ... This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to ... It is a multi-domain matrix glycoprotein that has been shown to be a natural inhibitor of neovascularization and tumorigenesis ...
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix (ECM) in normal ... "Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia ... 72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is ... The ectodomain of the 44-kDa form of membrane type-1 matrix metalloproteinase does not modulate gelatinase A activation". J. ...
Loukopoulos P, Mungall BA, Straw RC, Thornton JR, Robinson WF (July 2003). "Matrix metalloproteinase-2 and -9 involvement in ... 2 (635). doi:10.1038/ncprheum0347. Retrieved 22 July 2013. Xue S, Qiao J, Pu F, Cameron M, Yang JJ (January 2013). "Design of a ... 35 (2): 128-40. doi:10.1016/j.nbd.2008.10.003. PMC 2747727 . PMID 19010417. Egerer K, Feist E, Burmester GR (March 2009). "The ... Commonly, peptides, antibodies, or small ligands, and small protein domains, such as HER-2 affibodies, have been applied to ...
Egeblad, M; Werb, Z (March 2002). "New functions for the matrix metalloproteinases in cancer progression". Nature Reviews. ... particularly matrix metalloproteinases. The group also investigates the role of these effects on biological processes such as ... Kain, K. H. (10 August 2010). "The extracellular matrix and disease: an interview with Zena Werb". Disease Models & Mechanisms ... Werb's research group studies the effects on cells of the extracellular matrix microenvironment and its component proteases, ...
Deshane J, Garner CC, Sontheimer H (February 2003). "Chlorotoxin inhibits glioma cell invasion via matrix metalloproteinase-2 ... 264 (2 Pt 1): C361-9. PMID 8383429. Lippens G, Najib J, Wodak SJ, Tartar A (January 1995). "NMR sequential assignments and ... 39 (2): 162-73. doi:10.1002/glia.10083. PMID 12112367. Mamelak AN, Rosenfeld S, Bucholz R, et al. (August 2006). "Phase I ... Chlorotoxin exerts a dual effect on MMP-2: it inhibits the enzymatic activity of MMP-2 and causes a reduction in the surface ...
Another major contributor to angiogenesis is matrix metalloproteinase (MMP). MMPs help degrade the proteins that keep the ... "Matrix metalloproteinase activity is required for activity-induced angiogenesis in rat skeletal muscle". American Journal of ... These cells begin laying collagen fibers into the core to provide an extracellular matrix for growth of the vessel lumen. ... The endothelial cells then proliferate into the surrounding matrix and form solid sprouts connecting neighboring vessels. As ...
"Chlorotoxin Inhibits Glioma Cell Invasion via Matrix Metalloproteinase-2". The Journal of Biological Chemistry. 278 (6): 4135- ... 7 (2): 369-79. Chowdhury, F. R.; Ahasan, H A M. Nazmul; Rashid, A K M. Mamunur; Mamun, A. Al; Khaliduzzaman, S. M. (2007). " ... doi:10.1016/0166-2236(94)90092-2. Ahasan, H A M N, A. A. Mamun, S. R. Karim, M. A. Baker, E. A. Gazi, and C. S. Bala (2004) " ... 64 (2): 283-303. doi:10.1016/j.brainresrev.2010.04.011. Griffith, Harold R.; Johnson, G. Enid (1942). "The Use Of Curare In ...
Nagase, H; Woessner Jr, JF (1999). "Matrix metalloproteinases". J. Biol. Chem. 274 (31): 21491-21494. doi:10.1074/jbc.274.31. ... Hiller, O; Allen, E; Apel, IJ; Gyetko, MR; Weiss, SJ (1998). "Matrix metalloproteinases regulate meovascularization by acting ... Schlingemann, R; Oosterwijk, E; Wesseling, P; Rietveld, FJ; Ruiter, DJ (1996). "Stromal matrix metalloproteinase-9 regulates ... Coussens, L; Fingleton, B; Matrisian, LM (2002). "Matrix metalloproteinase inhibitors and cancer: trials and tribulations". ...
"MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators". Molecular and Cellular Biology. 28 (17 ... 133 (2): 647-58. doi:10.1053/j.gastro.2007.05.022. PMC 4285346 . PMID 17681183. Gabriely G, Wurdinger T, Kesari S, Esau CC, ... 6 (2): e16979. doi:10.1371/journal.pone.0016979. PMC 3037403 . PMID 21347332. Schramedei K, Mörbt N, Pfeifer G, Läuter J, ... 114 (2): 404-14. doi:10.1182/blood-2008-09-179150. PMC 2927176 . PMID 19398721. Yelamanchili SV, Chaudhuri AD, Chen LN, Xiong H ...
Like other tetracyclines, incyclinide inhibits matrix metalloproteinases. Reuters: CollaGenex says incyclinide ineffective for ... CS1 maint: Multiple names: authors list (link) H. Spreitzer (2 July 2007). "Neue Wirkstoffe - Incyclinid". Österreichische ...
"Matrix metalloproteinases: regulators of the tumor microenvironment". Cell. 141 (1): 52-67. doi:10.1016/j.cell.2010.03.015. PMC ... 7 (2): 225-30. doi:10.1038/sj.embor.7400600. PMC 1369251 . PMID 16374507. Zhong, ZH; Jiang, WQ; Cesare, AJ; Neumann, AA; Wadhwa ... 66 (2): 83-92. PMID 22525466. Chang, F; Lee, JT; Navolanic, PM; Steelman, LS; Shelton, JG; Blalock, WL; Franklin, RA; McCubrey ... 1796 (2): 75-90. doi:10.1016/j.bbcan.2009.03.002. PMID 19306912. Reddel, RR (2014). "Telomere maintenance mechanisms in cancer ...
... (EC 3.4.24.35, 92-kDa gelatinase, matrix metalloproteinase 9, type V collagenase, 92-kDa type IV collagenase, ... and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant ... "Matrix metalloproteinase-9 activates TGF-β and stimulates fibroblast contraction of collagen gels". American Journal of ... "Matrix metalloproteinase gelatinase B (MMP-9) coordinates and effects epithelial regeneration". The Journal of Biological ...
Maskos K, Bode W (November 2003). "Structural basis of matrix metalloproteinases and tissue inhibitors of metalloproteinases". ... Okada Y, Hashimoto G (2001). "[Degradation of extracellular matrix by matrix metalloproteinases and joint destruction]". ... Matrix metalloproteinase-1 (MMP-1) also known as interstitial collagenase and fibroblast collagenase is an enzyme that in ... A specific region (183)RWTNNFREY(191) as been identified as a critical segment of matrix metalloproteinase 1 for the expression ...
"Engineered Sarafotoxins as Tissue Inhibitor of Metalloproteinases-like Matrix Metalloproteinase Inhibitors". Journal of ... 2007), are using C-terminally truncated SRTX-b to act as a matrix metalloproteinase inhibitor. The removal of the C-terminal ... the matrix metalloproteinase inhibitory activity is regained and enhanced. This modified sarafotoxin is useful for treating ... eliminates its toxic vasopressive activity and also the matrix metalloproteinase inhibitor activity, however with further amino ...
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... "Entrez Gene: MMP11 matrix metallopeptidase 11 (stromelysin 3)". Nagase H, Woessner JF (1999). "Matrix metalloproteinases". J. ... 2003). "Hepatocyte growth factor receptor, matrix metalloproteinase-11, tissue inhibitor of metalloproteinase-1, and ... Stromelysin-3 (SL-3) also known as matrix metalloproteinase-11 (MMP-11) is an enzyme that in humans is encoded by the MMP11 ...
The involvement of AP-1 in the aforementioned inflammatory cascade activates matrix metalloproteinases, which contribute to ... 12 (2): e30-5. PMID 23377402.. *^ a b Danby FW (27 January 2015). Acne: Causes and Practical Management. John Wiley & Sons. pp ... 50 (Pt 2): 95-107. doi:10.1258/acb.2012.012159. PMID 23431485.. *^ a b c Katsambas AD, Dessinioti C (2010). "Hormonal therapy ... p. 2. ISBN 978-0071440196. .. *^ Hoeger PH, Irvine AD, Yan AC (2011). "Chapter 79: Acne". Harper's Textbook of Pediatric ...