"Matrix metalloproteinases collagenase-2, macrophage elastase, collagenase-3, and membrane type 1-matrix metalloproteinase ... Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... "Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human optic nerve head astrocytes". Glia ... Matrix metalloproteinase-12 (MMP-12) also known as macrophage metalloelastase (MME) or macrophage elastase (ME) is an enzyme ...

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... 1997). "Matrix metalloproteinases, tumor necrosis factor and multiple sclerosis: an overview". J. Neuroimmunol. 72 (2): 155-61 ... Neutrophil collagenase, also known as matrix metalloproteinase-8 (MMP-8) or PMNL collagenase (MNL-CL), is a collagen cleaving ... A distinct gene product with homology to other matrix metalloproteinases". J. Biol. Chem. 265 (20): 11421-4. doi:10.1016/S0021- ...

... matrix metalloproteinase pump 1, PUMP-1 proteinase, PUMP, metalloproteinase pump-1, putative metalloproteinase, MMP). Human MMP ... Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... Matrilysin also known as matrix metalloproteinase-7 (MMP-7), pump-1 protease (PUMP-1), or uterine metalloproteinase is an ... Woessner JF, Taplin CJ (November 1988). "Purification and properties of a small latent matrix metalloproteinase of the rat ...

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix (ECM) in normal ... "Structural insight into the complex formation of latent matrix metalloproteinase 2 with tissue inhibitor of metalloproteinase 2 ... "Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia ... "Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity". J. Biol. ...

Hua, H.; Li, M.; Luo, T; Yin, Y.; Jiang, Y (2011). "Matrix Metalloproteinases in Tumorigenesis: an Evolving Paradigm". Cellular ... They all contain twelve cysteine residues that form six disulfide bonds. These bonds are critical for the conformation of the N ... Metalloprotease inhibitors are cellular inhibitors of the Matrix metalloproteinases (MMPs). MMPs belong to a family of zinc- ... Brown, P. D. (1997). "Matrix metalloproteinase inhibitors in the treatment of cancer". Medical Oncology. 14 (1): 1-10. doi: ...

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix proteins and during ... The mechanism for MMP-3 is a variation on a larger theme seen in all matrix metalloproteinases. In the active site, a water ... Stromelysin-1 also known as matrix metalloproteinase-3 (MMP-3) is an enzyme that in humans is encoded by the MMP3 gene. The ... Lee JY, Choi HY, Ahn HJ, Ju BG, Yune TY (Nov 2014). "Matrix metalloproteinase-3 promotes early blood-spinal cord barrier ...

The activity of matrix metalloproteinase-9 was decreased by treatment. Clinical and MRI outcomes in this study were supported ... Levels of interleukin-12 (IL-12), which at high levels might antagonize the proinflammatory IL-12 receptor, were elevated over ... 118 (12): 989-992. doi:10.1001/archderm.1982.01650240033017. PMID 6216858. Eady EA, Gloor M, Leyden JJ (2003). " ... 166 (12): 7527-7533. doi:10.4049/jimmunol.166.12.7527. PMID 11390507. Nirmalananthan N, Greensmith L (December 2005). " ...

Matrix metalloproteinases (MMPs) MMP-2 is the main metalloprotease secreted by breast-cancer cells or induced in the adjacent ... Cell-cell and cell-ECM matrix adhesion, motility, and localised proteolysis are mediated mainly by matrix metalloproteases ( ... "Cancer cell-associated fibronectin induces release of matrix metalloproteinase-2 from normal fibroblasts". Cancer Research. ... The primary extracellular matrix components and cell-surface receptors which aid in metastasis are: Integrin signalling ...

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... Köhrmann A, Kammerer U, Kapp M, Dietl J, Anacker J (2009). "Expression of matrix metalloproteinases (MMPs) in primary human ... Hegedüs L, Cho H, Xie X, Eliceiri GL (2008). "Additional MDA-MB-231 breast cancer cell matrix metalloproteinases promote ... Yang M, Kurkinen M (1998). "Cloning and characterization of a novel matrix metalloproteinase (MMP), CMMP, from chicken embryo ...

"Dentin Matrix Protein 1 Enhances Invasion Potential of Colon Cancer Cells by Bridging Matrix Metalloproteinase-9 to Integrins ... Dentin matrix acidic phosphoprotein 1 is a protein that in humans is encoded by the DMP1 gene. Dentin matrix acidic ... Ogbureke KU, Fisher LW (2005). "Renal expression of SIBLING proteins and their partner matrix metalloproteinases (MMPs)". ... 2004). "Dentin matrix protein 1 is expressed in human lung cancer". J. Bone Miner. Res. 18 (8): 1506-12. doi:10.1359/jbmr. ...

"Entrez Gene: MMP21 matrix metallopeptidase 21". Brinckerhoff CE, Matrisian LM (2002). "Matrix metalloproteinases: a tail of a ... Matrix metalloproteinase-21 (MMP-21) is an enzyme that in humans is encoded by the MMP21 gene. This gene encodes a member of ... 2004). "The matrix metalloproteinase-21 gene 572C/T polymorphism and the risk of breast cancer". Anticancer Res. 24 (1): 199- ... 2003). "Matrix metalloproteinase-21, the human orthologue for XMMP, is expressed during fetal development and in cancer". Gene ...

Matrix metalloproteinase 28, also known as epilysin, belongs to a family of proteins known as matrix metalloproteinases which ... Matrix metalloproteinases are commonly known to degrade the extracellular matrix, alongside regulating cell surface receptors ... June 2009). "Expression and function of matrix metalloproteinase (MMP)-28". Matrix Biology. 28 (5): 263-272. doi:10.1016/j. ... Matrix metalloproteinase 28 also known as epilysin is an enzyme that in humans is encoded by the MMP28 gene. ...

For example, Matrix metalloproteinases (MMPs) are known to be up-regulated in cancer sites. By inserting an infection blocking ... 2011). "Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting". FEBS J. 278 (1): 16-27. ... 17 (12): 2088-2095. doi:10.1038/mt.2009.184. PMC 2788045. PMID 19672246. Gialeli, C.; et al. ( ...

... places it in the mammalian matrix metalloproteinase family". Biochemistry. 30 (25): 6115-23. doi:10.1021/bi00239a005. PMID ... 9 (9): 3003-12. doi:10.1002/j.1460-2075.1990.tb07493.x. PMC 552018. PMID 2167841. Nomura K, Tanaka H, Kikkawa Y, Yamaguchi M, ...

2006). "Overexpression of cathepsin F, matrix metalloproteinases 11 and 12 in cervical cancer". BMC Cancer. 5 (1): 68. doi: ... 380 (12): 1439-42. doi:10.1515/BC.1999.185. PMID 10661872. S2CID 28469574. Shi GP, Bryant RA, Riese R, et al. (2000). "Role for ... 114 (12): 4571-4578. doi:10.1007/s00436-015-4703-9. ISSN 0932-0113. PMC 4917378. PMID 26344868. Korkmaz, Huseyin; Findik, Duygu ...

Fini ME, Cui TY, Mouldovan A, Grobelny D, Galardy RE, Fisher SJ (1991). "An inhibitor of the matrix metalloproteinase ... Ilomastat (INN), (codenamed GM6001, proprietary name Galardin®) is a broad-spectrum matrix metalloproteinase inhibitor. This ... Santiskulvong C, Rozengurt E (November 2003). "Galardin (GM 6001), a broad-spectrum matrix metalloproteinase inhibitor, blocks ... "Treatment of alkali-injured rabbit corneas with a synthetic inhibitor of matrix metalloproteinases". Invest. Ophthalmol. Vis. ...

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... "Entrez Gene: MMP11 matrix metallopeptidase 11 (stromelysin 3)". Nagase H, Woessner JF (1999). "Matrix metalloproteinases". J. ... 2003). "Hepatocyte growth factor receptor, matrix metalloproteinase-11, tissue inhibitor of metalloproteinase-1, and ... Stromelysin-3 (SL-3) also known as matrix metalloproteinase-11 (MMP-11) is an enzyme that in humans is encoded by the MMP11 ...

Melting ulcers reflect inappropriate collagenolysis of the corneal stroma, by matrix-metalloproteinases (MMPs). Bacterial ... Untreated this can lead to perforation within 12 hours (so act hard and fast!). There are several therapeutic options for ...

Ekbote AV, Danda S, Zankl A, Mandal K, Maguire T, Ungerer K (2014). "Patient with mutation in the matrix metalloproteinase 2 ( ... In 2005, a patient with Winchester syndrome was shown to have mutations in the matrix metalloproteinase 2 (MMP2) gene. A 2006 ... The protein inactivation mutation is found on the matrix metalloproteinase 2 gene (MMP2). MM2 is responsible for bone ... "Winchester syndrome caused by a homozygous mutation affecting the active site of matrix metalloproteinase 2". Clin Genet. 67 (3 ...

2008). "Correlation between beta-catenin widespread nuclear expression and matrix metalloproteinase-7 overexpression in ... 39 (12): 1802-8. doi:10.1016/j.humpath.2008.05.005. PMID 18715618. Wang L, O'Leary H, Fortney J, Gibson LF (2007). "Ph+/VE- ...

"High glucose alters matrix metalloproteinase expression in two key vascular cells: potential impact on atherosclerosis in ... "Effects of glucose on matrix metalloproteinase and plasmin activities in mesangial cells: possible role in diabetic nephropathy ... "12 Questions with Professor Alison Heather - Otago Medical Research Foundation". www.omrf.org.nz. "Otago Professor finds ...

"Melanoma expression of matrix metalloproteinase-23 is associated with blunted tumor immunity and poor responses to ... MMP-23 belongs to the family of zinc- and calcium-dependent matrix metalloproteases. It is anchored in the cell membrane by an ... Pan T, Gröger H, Schmid V, Spring J (July 1998). "A toxin homology domain in an astacin-like metalloproteinase of the jellyfish ... ShK-186 also shares sequence and structural similarity to a ShK-like domain in matrix metalloprotease 23, which may cause the ...

"Testican 2 abrogates inhibition of membrane-type matrix metalloproteinases by other testican family proteins". Cancer Research ... are components of the extracellular matrix. SPOCK2 encodes a member of a novel Ca(2+)-binding proteoglycan family.[supplied by ... 63 (12): 3364-9. PMID 12810672. Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, ... 12 (11): 1773-84. doi:10.1101/gr.406902. PMC 187542. PMID 12421765. Nakada M, Miyamori H, Yamashita J, Sato H (June 2003). " ...

Nakada M, Miyamori H, Yamashita J, Sato H (2003). "Testican 2 abrogates inhibition of membrane-type matrix metalloproteinases ... 63 (12): 3364-9. PMID 12810672. Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of ...

Cox JH, Starr AE, Kappelhoff R, Yan R, Roberts CR, Overall CM (December 2010). "Matrix metalloproteinase 8 deficiency in mice ... validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy". Nature Reviews Cancer. 6 (3): 227- ... 62 (12): 3645-3655. doi:10.1002/art.27757. PMID 21120997.{{cite journal}}: CS1 maint: multiple names: authors list (link) ... 12 (5): e1001869. doi:10.1371/journal.pbio.1001869. PMC 4035269. PMID 24865846.{{cite journal}}: CS1 maint: multiple names: ...

"Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity". The Journal ... matrix metalloproteinase, thrombin, cathepsin, and elastase. Thrombospondin-1 binds to the reelin receptors, ApoER2 and VLDLR, ... This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to ... It is a multi-domain matrix glycoprotein that has been shown to be a natural inhibitor of neovascularization and tumorigenesis ...

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal ... Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the ... Nguyen Q, Murphy G, Hughes CE, Mort JS, Roughley PJ (October 1993). "Matrix metalloproteinases cleave at two distinct sites on ... Conca W, Willmroth F (June 1994). "Human T lymphocytes express a member of the Matrix Metalloproteinase gene family". Arthritis ...

Lyu J, Joo CK (2005). "Wnt-7a up-regulates matrix metalloproteinase-12 expression and promotes cell proliferation in corneal ... 4 (12): 1267-75. doi:10.1091/mbc.4.12.1267. PMC 275763. PMID 8167409. Huguet EL, McMahon JA, McMahon AP, et al. (1994). " ...

1998). "Serum amyloid A protein induces production of matrix metalloproteinases by human synovial fibroblasts". Lab. Invest. 78 ... 1997). "Extracellular matrix-anchored serum amyloid A preferentially induces mast cell adhesion". Am. J. Physiol. 273 (1 Pt 1 ... 24 (11-12): 795-803. doi:10.1007/BF00554519. PMID 3800865. S2CID 8124689. Meek RL, Hoffman JS, Benditt EP (1986). " ... 46 (12): 1377-84. doi:10.1177/002215549804601206. PMID 9815279. v t e (Articles with short description, Short description ...

Clinical assessment of the effect of a matrix metalloproteinase inhibitor on aphthous ulcers. Acta Odontol Scand. 2009;67(1):25 ... 2007;152(12):2225-36. Holbrook, W. P., Kristmundsdóttir, T., Loftsson, T. Aqueous hydrocortisone mouthwash solution: clinical ... 2017). Fundargerð háskólaráðs 12. janúar 2017. Retrieved March 27, 2020. Mbl.is. (2001, May 11). Markmiðið er efling ...