This gene encodes a protein that binds to matrix attachment regions. The protein functions as a tumor suppressor and cell cycle ... binds the Scaffold/Matrix-associated region at the T cell receptor beta locus". Genomics. 68 (1): 93-6. doi:10.1006/geno. ... Protein BANP is a protein that can be found in humans, it is encoded by the BANP gene. It is a member of the human gene family ... Its official name is BTG3 associated with nuclear protein. It plays a role in DNA binding, chromatin regulation, repressor, ...

MARs is a special AT-rich sequence-binding protein 1, predominantly expressed in thymocytes, binds to matrix attachment regions ... Uncharacterized protein C1orf21, also known as Proliferation-Inducing Protein 13, is a protein that in humans is encoded by the ... "Protein BLAST: search protein databases using a protein query". blast.ncbi.nlm.nih.gov. Retrieved 2019-02-28. "C1orf21 Gene - ... binding sites have been predicted through Genomatix. Some important binding cites include MYRE, MARs, and Bright. MYRE is a ...

This gene encodes a DNA-binding protein that has specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA ... the nuclear matrix, or both. Scaffold attachment factors are a subset of nuclear matrix proteins (NMP) with enriched binding to ... a novel nuclear DNA binding protein from HeLa cells with high affinity for nuclear matrix/scaffold attachment DNA elements". ... Oesterreich S, Lee AV, Sullivan TM, Samuel SK, Davie JR, Fuqua SA (1997). "Novel nuclear matrix protein HET binds to and ...

... is a DNA-binding protein that specifically binds nuclear matrix attachment regions and is involved in transcriptional ... Special AT-rich sequence-binding protein 2 (SATB2) also known as DNA-binding protein SATB2 is a protein that in humans is ... The protein contains two degenerate homeodomain regions known as CUT domains (amino acid 352-437 and 482-560) and a classical ... Dobreva G, Dambacher J, Grosschedl R (December 2003). "SUMO modification of a novel MAR-binding protein, SATB2, modulates ...

Scaffold/Matrix attachment region-binding protein 1; also known as BANP), a tumour-suppressor MAR-binding protein that down- ... It has been suggested to mediate protein-DNA and protein-protein interactions during chromatin organization and transcription. ... 2022-02-10). "Distinct structural bases for sequence-specific DNA binding by mammalian BEN domain proteins". Genes & ... E5R protein from Chordopoxvirus virosomes, which is found in cytoplasmic sites of viral DNA replication. Several proteins of ...

... matrix attachment regions and cut-like protein x/CCAAT-displacement protein and B cell regulator of IgH transcription binding ... This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to ... AT-rich interactive domain-containing protein 3A is a protein that in humans is encoded by the ARID3A gene. ... "A novel E2F binding protein with Myc-type HLH motif stimulates E2F-dependent transcription by forming a heterodimer". Oncogene ...

The SAP domain can recognize and bind to AT-rich DNA sequences present in scaffold-attachment regions/matrix-attachment regions ... 2000). "SAF-Box, a conserved protein domain that specifically recognizes scaffold attachment region DNA". Mol Cell Biol. 20 (20 ... E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several ... The Pro-Ile-Asn-Ile-Thr (PINIT) motif represents a highly conserved region of PIAS proteins, which was shown to be involved in ...

"A novel DNA-binding motif in the nuclear matrix attachment DNA-binding protein SATB1". Molecular and Cellular Biology. 14 (3): ... Gotzmann J, Meissner M, Gerner C (May 2000). "The fate of the nuclear matrix-associated-region-binding protein SATB1 during ... region in the human CD8 gene complex by colocalization of DNase I hypersensitive sites and matrix attachment regions which bind ... of the Xlr nuclear protein in immature thymocytes and colocalization with the matrix-associated region-binding SATB1 protein". ...

These A/T rich regions are known as matrix-attachment regions. Once bound, the matrix-attachment regions anchor loops of ... In essence, the RING-finger-like zinc-binding domain of the PIAS protein assists in the attachment of a SUMO protein to the ... Attachment of a SUMO protein to the target allows for protein-protein interaction between PIAS and the transcription factor. ... The RING-finger-like zinc-binding domain is present in all PIAS proteins. RLD is essential for PIAS proteins to function as E3 ...

... scaffold/matrix attachment regions), the DNA regions that are known to attach genomic DNA to variety of nuclear proteins, show ... The nuclear matrix proteome consists of structural proteins, chaperones, DNA/RNA-binding proteins, chromatin remodeling and ... September 2007). "Genome-wide prediction of matrix attachment regions that increase gene expression in mammalian cells". Nature ... The presence of intra-cellular proteins is common ground, and it is agreed that proteins such as the Scaffold, or Matrix ...

... along with Differentially-methylated Region-1 (DMR1) and Matrix Attachment Region −3 (MAR3). These three DNA sequences bind to ... "Transferrin binds insulin-like growth factors and affects binding properties of insulin-like growth factor binding protein-3". ... The protein CTCF is involved in repressing expression of the gene, by binding to the H19 imprinting control region (ICR) ... "Structural determinants of ligand and cell surface binding of insulin-like growth factor-binding protein-3". The Journal of ...

Yamasaki, K.; Akiba, T.; Yamasaki, T.; Harata, K. (2007). "Structural basis for recognition of the matrix attachment region of ... Proteins display two modes of DNA binding, which hinge on the homeodomain and on the linker that separates it from the CUT ... In molecular biology, the CUT domain (also known as ONECUT) is a DNA-binding motif which can bind independently or in ... Lannoy VJ, Burglin TR, Rousseau GG, Lemaigre FP (May 1998). "Isoforms of hepatocyte nuclear factor-6 differ in DNA-binding ...

... nuclear matrix attachment region, and mitochondrial DNA sequence elements from cultured mouse and human fibroblasts". DNA Cell ... Cyclin-T2 is a protein that in humans is encoded by the CCNT2 gene. The protein encoded by this gene belongs to the highly ... Nguyen VT, Kiss T, Michels AA, Bensaude O (2001). "7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T ... Kwak YT, Ivanov D, Guo J, Nee E, Gaynor RB (1999). "Role of the human and murine cyclin T proteins in regulating HIV-1 tat- ...

... region in the human CD8 gene complex by colocalization of DNase I hypersensitive sites and matrix attachment regions which bind ... Marine J, Winoto A (Aug 1991). "The human enhancer-binding protein Gata3 binds to several T-cell receptor regulatory elements ... "Homo sapiens GATA binding protein 3 (GATA3), RefSeqGene on chromosome - Nucleotide - NCBI". www.ncbi.nlm.nih.gov. 2019-05-21. " ... "Homo sapiens GATA binding protein 3 (GATA3), transcript variant 2, mRN - Nucleotide - NCBI". www.ncbi.nlm.nih.gov. 2019-05-19 ...

... domains at specific DNA sequences called matrix attachment regions (MAR). A MAR has a length of approximately 300-1000 bp and ... The nuclear lamin-associated membrane proteins are either integral or peripheral membrane proteins. The most important are ... Lamin A and B can also bind core histones through a sequence element in their tail domain. Chromatin that interacts with lamina ... by the subsequent activation and regulation of other protein kinases or by direct phosphorylation of structural proteins ...

2004). "Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1". ... Like other DUBs, otubains cleave proteins precisely at the ubiquitin (UB; see MIM 191339)-protein bond. ENSG00000277276 GRCh38 ... "Entrez Gene: OTUB2 OTU domain, ubiquitin aldehyde binding 2". Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome- ... scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur.437.1173R. doi: ...

"Scaffold/matrix attachment region elements interact with a p300-scaffold attachment factor A complex and are bound by ... The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene contains a RNA binding ... Kiledjian M, Dreyfuss G (1992). "Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box". ... "The glucocorticoid receptor is associated with the RNA-binding nuclear matrix protein hnRNP U". J. Biol. Chem. 272 (45): 28471- ...

"Scaffold/matrix attachment region elements interact with a p300-scaffold attachment factor A complex and are bound by ... "cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response ... "p300/cAMP-response-element-binding-protein ('CREB')-binding protein (CBP) modulates co-operation between myocyte enhancer ... Ko L, Cardona GR, Chin WW (May 2000). "Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions ...

This CYC-CLK protein complex binds to E-box elements in promoter regions of the genes period and timeless, functioning as a ... melanogaster cycle gene can either be found in chromosome 3 or in scaffold/matrix attachment regions. In each case, the ... Cloning of the cyc gene revealed that it encodes a novel bHLH-PAS protein related to mammalian bmal1, and that it likely binds ... After the PER and TIM proteins accumulate in the cytoplasm and bind together, the PER-TIM complex translocates to the nucleus. ...

... aureus expresses fibronectin-binding proteins, which promote binding to mucosal cells and tissue matrices. This protein is also ... that binds IgG, but also other targets for MSCRAMMs are known, such as fibronectin. Protein M binds to the Fc region of certain ... adhesin proteins mediate the initial attachment of bacteria to host tissue, providing a critical step to establish infection. ... On its surface, protein A is expressed, which binds to the Fc region of IgG antibodies (the default antibody type, dealing with ...

"A nuclear matrix attachment region upstream of the T cell receptor beta gene enhancer binds Cux/CDP and SATB1 and modulates ... CASP protein is approximately 80 kD. It lacks the DNA binding region of CUTL1, but instead contains a trans-membrane domain ... The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It regulates gene expression, ... Cux1 (CUTL1, CDP, CDP/Cux) has been shown to interact with: CREB binding protein, Retinoblastoma protein, and SATB1 These ...

... through the cell membrane via transmembrane integrin proteins, to the extracellular matrix. Focal adhesions form and dissipate ... region of focal adhesion kinase is a four-helix bundle that binds paxillin". Nat. Struct. Biol. 9 (2): 101-6. doi:10.1038/ ... and migration by localizing its protein kinase activity at the junction of internal cytoskeleton and external cell attachment ... Programmed cell death protein 10 (PDCD10)/Cerebral Cavernous Malformation protein 3 (CCM3) and GIT1/GIT2. Hayashi I, Vuori K, ...

... also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans (e.g ... The V-region contains the binding site for α4β1 integrins. It is present in most cellular fibronectin, but only one of the two ... The RGD sequence (Arg-Gly-Asp) is located in III10 and is the site of cell attachment via α5β1 and αVβ3 integrins on the cell ... collagen-binding (I6-9), fibulin-1-binding (III13-14), heparin-binding and syndecan-binding (III12-14). Fibronectin has ...

The G glycoprotein ectodomain assembles as a homotetramer to form the viral anti-receptor or attachment protein, which binds to ... Six structural proteins are generated: N (nucleocapsid), P (phosphoprotein), M (matrix), F (fusion), G (glycoprotein) and L ( ... the linker region and finally, at the C-terminal, four heads which contain host cell receptor binding domains. Each head ... The G protein head domain is also highly antigenic, inducing head-specific antibodies in primate models. As such, it is a prime ...

... binds the juxtamembrane region of the cadherin. γ-catenin or gamma-catenin (plakoglobin) binds the catenin-binding region of ... They can appear as bands encircling the cell (zonula adherens) or as spots of attachment to the extracellular matrix (focal ... Adherens junctions are composed of the following proteins: cadherins. The cadherins are a family of transmembrane proteins that ... are protein complexes that occur at cell-cell junctions and cell-matrix junctions in epithelial and endothelial tissues, ...

Fusion proteins and attachment proteins appear as spikes on the virion surface. Matrix proteins inside the envelope stabilise ... H/HN/G - the cell attachment proteins span the viral envelope and project from the surface as spikes. They bind to proteins on ... Extracistronic (noncoding) regions include: A 3' leader sequence, 50 nucleotides in length, which acts as a transcriptional ... This is probably due to the advantage of having all RNA bound by N protein (since N binds hexamers of RNA). If RNA is left ...

On the surface of cells, there are many proteins. Some proteins are involved in recognition, attachment or transportation. The ... The space inside the mitochondria is called the mitochondrial matrix, while the region outside is the cytosol. The outer ... in the mitochondrial matrix. In the second step, citrate would bind to citrate transporters. The shuttle delivers citrate from ... These genes regulate different proteins synthesis, including carrier proteins and certain enzymes. The replication of ...

"Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1". Mammalian ... which are known as protein coding genes. A disease associated with this gene is emphysema, due to aat protein deficiency. ... Rollini P, Fournier RE (December 1997). "Molecular linkage of the human alpha 1-antitrypsin and corticosteroid-binding globulin ... The reference genome contains the start codon mutation and has a coding region deletion. A three-dimensional model of SERPINA2 ...

... a matrix protein (M), a fusion protein (F), a hemagglutinin-neuraminidase (Hn) protein and a large polymerase protein (L). A ... The Hn protein is made up of a stalk and a globular head that contains receptor-binding capabilities that bind to sialic acid ... The genome encodes six viral proteins that are separated from each other via intergenic regions that are between 3-23 ... interactions between the Hn and F proteins cause conformational changes in the respective proteins controlling the attachment ...

... matrix attachment regions MeSH G06.184.603.080.689 - regulatory sequences, nucleic acid MeSH G06.184.603.080.689.330 - enhancer ... protein conformation MeSH G06.184.603.790.709.550 - protein structure, quaternary MeSH G06.184.603.790.709.600 - protein ... MeSH G06.184.154.147 - allosteric site MeSH G06.184.154.290 - bay region (chemistry) MeSH G06.184.154.309 - binding, ... locus control region MeSH G06.184.603.080.689.650 - operator regions (genetics) MeSH G06.184.603.080.689.675 - promoter regions ...