A mammary tumor is a neoplasm originating in the mammary gland. It is a common finding in older female dogs and cats that are ... There are many differences between mammary tumors in animals and breast cancer in humans, including tumor type, malignancy, and ... Benjamin S, Lee A, Saunders W (1999). "Classification and behavior of canine mammary epithelial neoplasms based on life-span ... Spayed rats have a decreased risk of developing mammary tumors. Most mammary tumors in mice are adenocarcinomas. They can be ...

Laboratory mouse Animal testing on rodents Morris water maze Rat Genome Database Vandenbergh, J. G. (1 January 2000). "Use of ... The most common are adenomas of the pituitary and adenomas/adenocarcinomas of the adrenal cortex in both sexes, mammary gland ... Mac Kenzie, William; Garner, F. (1973). "Comparison of Neoplasms in Six Sources of Rats". JNCI: Journal of the National Cancer ... Institute for Laboratory Animal Research (ILAR). 32 (3): 4-8. doi:10.1093/ilar.32.3.4. Suckow, Mark A.; Weisbroth, Steven H.; ...

In animals, the bioavailability of hydroxyprogesterone caproate with intramuscular injection is nearly 100%, but its oral ... Dao TL (1975). "Pharmacology and Clinical Utility of Hormones in Hormone Related Neoplasms". In Sartorelli AC, Johns DG (eds ... Crowley LG, Macdonald I (April 1965). "Delalutin and estrogens for the treatment of advanced mammary carcinoma in the ... Crowley LG, Macdonald I (1962). "Clinical trial of delautin in the treatment of advanced mammary carcinoma in postmenopausal ...

Dunn, Thelma B. "Morphology of Mammary Tumors in Mice" (1958). "Studies of the Mammary-Tumor Agent of Strain RIII Mice". JNCI: ... "Histology of Some Neoplasms and Non-Neo-plastic Lesions Found in Wild Mice Maintained Under Laboratory Conditions". JNCI: ... She developed methods of inducing malignant tumors in the stomachs and intestines of experimental animals and studied the ... "Studies of the Mammary-Tumor Agent of Strain RIII Mice" (1961), "Further Studies of the Mammary Tumor Agent of Strain RIII Mice ...

The majority of deaths were caused by neoplasms, mainly mammary tumours. The Siamese also has a higher rate of morbidity. They ... April 2006). "Albinism in the domestic cat (Felis catus) is associated with a tyrosinase (TYR) mutation". Animal Genetics. 37 ( ... London: Hodder & Stoughton Wilson, Staci Layne (2007). Animal Movies Guide. Running Free Press. p. 16. ISBN 9780967518534. New ... "Congenital Deafness and Its Recognition". Veterinary Clinics of North America: Small Animal Practice. Retrieved 15 January 2015 ...

During this period he first had the idea to use mice to find a cure for mammary cancer in animals. Ansfield received his M.D. ... Ansfield, Fred J (1973). Chemotherapy of Malignant Neoplasms (Second ed.). Springfield, Illinois: Charles C Thomas. ISBN 0-398- ... 1958 Chemotherapy of Malignant Neoplasms, 1973 Chemotherapy of Disseminated Solid Tumors, 1966 Mehta, Minesh P.; Paliwal, ...

Annual Review of Animal Biosciences. 4 (1): 199-222. doi:10.1146/annurev-animal-022114-110911. PMC 6314649. PMID 26566160. Pang ... Other significant risk factors were a high intake of red meat, especially beef and pork (...) We found mammary tumor risk to be ... Cancer alters the DNA of cells and the mutated genetic material is passed on to daughter cells, resulting in neoplasms. The ... Veterinary oncology is the medical study of cancer in animals, and can be diagnosed and treated by specialized veterinarians ...

Animal. 41 (1-2): 19-28. doi:10.1290/0502010.1. PMID 15926856. S2CID 1995302. Przyborski SA (2001). "Isolation of human ... Smalley MJ, Clarke RB (January 2005). "The mammary gland "side population": a putative stem/progenitor cell marker?". Journal ... Misago N, Narisawa Y (September 2006). "Cytokeratin 15 expression in neoplasms with sebaceous differentiation". Journal of ... Clarke RB (December 2005). "Isolation and characterization of human mammary stem cells". Cell Proliferation. 38 (6): 375-86. ...

FDA routinely requires long-term animal studies before any drug can be marketed for human use. Following animal studies with ... In the early 1970s, MGA was found to be associated with mammary tumors in beagle dogs, and along with several other ... Frick J, Marberger H, Swoboda HP (May 1971). "[Hormone therapy of prostatic neoplasms]". Der Urologe (in German). 10 (3): 117- ... Small Animal Practice. 33 (2): 365-404, vii. doi:10.1016/S0195-5616(02)00130-4. PMID 12701517. Canetta R, Florentine S, Hunter ...

Furthermore, it leads to a phase delay of circadian rhythm in nocturnal and diurnal animal models. N-benzothiazolyl-2-phenyl ... Besides those, reduced CK1δ activity owing to the site N172D mutation of CK1δ decelerated mammary carcinoma progression, and ... hematopoietic malignancies and lymphoid neoplasms. Also decreased CK1δ mRNA expression levels have been observed in some cancer ... Ever since, CK1δ was investigated and described in various animals, plants, as well as parasites (Caenorhabditis elegans, 1998 ...

"The role of animal behaviour in the study of endocrine-disrupting chemicals". Animal Behaviour. 68 (4): 665-676. doi:10.1016/j. ... Neoplasms occurring in epithelial tissue such as the liver, gastrointestinal tract, and the pancreas have been linked to ... In females, this includes mammary glands, fallopian tubes, uterus, cervix, and vagina. In males, this includes the prostate, ... Alternatives to Laboratory Animals 31: 277-281. Boelsterli, Urs. Mechanistic Toxicology: The molecular basis of how chemicals ...

... control animal - control group - controlled clinical trial - controlled study - conventional therapy - conventional treatment ... mammary - mammogram - mammography - Mammotome - mantle field - marimastat - mast cell - mastectomy - mastocytoma - matrix ... neoplasm - nephrotomogram - nephrotoxic - nephroureterectomy - nerve block - nerve grafting - nerve-sparing radical ... animal model - annamycin - anorexia - ansamycin - antagonist - anterior mediastinotomy - anterior mediastinum - anthracenedione ...

In 1968, Jackson and Langham published the first NMR signals from a living animal, an anesthetized rat. In the 1970s, it was ... Irwin Weisman also found in 1972 that neoplasms display different relaxation times than corresponding normal tissue. Zenuemon ... "Distinction between the preneoplastic and neoplastic state of murine mammary glands". Proceedings of the National Academy of ... In research laboratories, human studies have been performed at 9.4 T (2006) and up to 10.5 T (2019). Non-human animal studies ...

Dissociated mammary cells from MMTV-PyMT: IRES: Luc; MTB (Internal ribosome entry site: Luciferin) animals (which were not ... It also confirms the genetic heterogeneity between the primary neoplasm of breast cancer patients and their respective ... In the non-fused mouse, the mammary gland would revert to a near virgin, but with this addition the mammary gland maintained ... Whey acidic protein (WAP), is another common promoter used to generate mouse mammary cancer models. For a list of other mammary ...

"A glimpse into Canada's highest containment laboratory for animal health: The National Centre for Foreign Animal Diseases". ... Male reproductive system - Mammary gland - Mandible - The mandible, lower jaw or jawbone is the largest, strongest and lowest ... Papillary - In oncology, papillary refers to neoplasms with projections ("papillae", from Latin, 'nipple') that have ... Plant life and animal life rely on many organs that co-exist in organ systems. Oral and maxillofacial surgery - is a surgical ...

As a mammary gland, the breast comprises lobules (milk glands at each lobe-tip) and the lactiferous ducts (milk passages), ... Obesity or being overweight in humans and most animals does not depend on body weight but on the amount of body fat - to be ... liposuction mammoplasty also is contraindicated for any woman whose mammograms indicate the presence of unevaluated neoplasms; ... The 2nd, 3rd, 4th, 5th, and 6th ribs of the thoracic cage are the structural supports for the mammary glands. Chest muscles. ...

Acral lentiginous melanoma Amelanotic melanoma Animal-type melanoma Desmoplastic melanoma (neurotropic melanoma, spindled ... neoplasms, and cysts are skin lesions that develop from the epidermal layer of the skin. Aberrant basal cell carcinoma ... Turner syndrome Ulnar-mammary syndrome Van Der Woude syndrome Von Hippel-Lindau syndrome Watson syndrome Werner syndrome (adult ... an overview with emphasis on the myeloid neoplasms". Chem. Biol. Interact. 184 (1-2): 16-20. doi:10.1016/j.cbi.2009.10.009. ...

Clark JH, Hardin JW, McCormack SA (1979). "Mechanism of action of estrogen agonists and antagonists". Journal of Animal Science ... Estrogens and Androgens in Mammary Cancer". JAMA: The Journal of the American Medical Association. 140 (15): 1214. doi:10.1001/ ... "Pharmacology and Clinical Utility of Hormones in Hormone Related Neoplasms". In Alan C. Sartorelli, David G. Johns (eds.). ... "Androgens and estrogens in the treatment of disseminated mammary carcinoma. Retrospective study of nine hundred forty-four ...

Rusyn I, Lemon SM (April 2014). "Mechanisms of HCV-induced liver cancer: what did we learn from in vitro and animal studies?". ... In 1936 John Joseph Bittner identified the mouse mammary tumor virus, an "extrachromosomal factor" (i.e. virus) that could be ... Stewart SE, Eddy BE, Borgese N (June 1958). "Neoplasms in mice inoculated with a tumor agent carried in tissue culture". ... A minority of persons (or animals) will go on to develop cancers after infection. This has complicated efforts to determine ...

TGF-β, which acts in the epithelial cells of the mammary gland as a potent tumor suppressor at the early stages of cancer, can ... Studies in animal models have demonstrated that metastases more often form after intravenous injection of tumor clusters rather ... The factors limiting the growth of malignant neoplasms include the basement membrane and various components of the surrounding ... The results of numerous experimental and clinical studies of malignant neoplasms have indicated that invasive growth and ...

Transgenic mice expressing either p75, p110 or p200 CUX1 in mammary epithelial cells develop mammary tumours with a low ... CUX1 is an animal gene. The name stands for Cut like homeobox 1. The term "cut" derives from the "cut wing" phenotype observed ... "Genome integrity of myeloproliferative neoplasms in chronic phase and during disease progression". Blood 2011, 118:167-76. ... Transgenic mice expressing this transcript in mammary epithelial cells were shown to develop mammary tumours with metastasis to ...

Animals, typically rodents, are often used in cancer research and studies of natural cancers in larger animals may benefit ... They form a subset of neoplasms. A neoplasm or tumor is a group of cells that have undergone unregulated growth and will often ... The German professor Wilhelm Fabry believed that breast cancer was caused by a milk clot in a mammary duct. The Dutch professor ... Across wild animals, there is still limited data on cancer. Nonetheless, a study published in 2022, explored cancer risk in ( ...

The Notch signaling pathway is a highly conserved cell signaling system present in most animals. Mammals possess four different ... "Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells". Breast Cancer Research. 6 (6): R605 ... is broken by chromosomal translocations in T lymphoblastic neoplasms". Cell. 66 (4): 649-61. doi:10.1016/0092-8674(91)90111-B. ... Hedgehog signaling and Scl T cell lineage commitment from common lymphoid precursor regulation of cell-fate decision in mammary ...

There are also reports of the use of thymidine kinase as a tumor marker in domestic animals, in horse, in dogs in cats and in ... Lipkin M, Deschner E, Troncale F (1970). "Cell differentiation and the development of colonic neoplasms". CA: A Cancer Journal ... and canine mammary tumors (CMTs): implications for TK1 as a proliferation biomarker". BMC Veterinary Research. 10: 228. doi: ... "Increased activities of thymidine kinase isozymes in human mammary tumours". The British Journal of Surgery. 73 (4): 272-3. doi ...

... as well as eliminating infected animals and screening incoming animals, should clear the problem very quickly. Imported animals ... Its expression is also increased in a wide range of other malignant neoplasms. Factor X (F10) is frequently expressed in normal ... immunohistochemical analysis in mammary carcinoma in situ, invasive carcinomas and their lymph node metastasis". Anticancer ... and has oncolytic properties demonstrated in animal models and in naturally-occurring cancers in animals. SeV's ability to fuse ...