... (musculoaponeurotic fibrosarcoma) proteins are basic region leucine zipper-type transcription factors that can bind ... Toki, T (1997). "Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif ... "NCBI Gene". Igarashi, K (1994). "Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf ... The Maf family is divided into two subfamilies, as follows: the large Maf subfamily (c-Maf, MafA, MafB, and NRL); and the small ...
"Small Maf proteins interact with the human transcription factor TCF11/Nrf1/LCR-F1". Nucleic Acids Res. 24 (21): 4289-97. doi: ... "Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif". Oncogene. 14 ( ... key transcription factor for eukaryotic initiation factor-2 alpha is strongly homologous to developmental transcription factors ... Marini MG, Chan K, Casula L, Kan YW, Cao A, Moi P (1997). "hMAF, a small human transcription factor that heterodimerizes ...
... is one of the small Maf proteins, which are basic region and leucine zipper (bZIP)-type transcription factors. The HUGO ... Transcription factor MafG is a bZip Maf transcription factor protein that in humans is encoded by the MAFG gene. ... "Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor". Molecular ... "Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor". Molecular ...
"Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif". Oncogene. 14 ( ... "Small Maf proteins interact with the human transcription factor TCF11/Nrf1/LCR-F1". Nucleic Acids Research. 24 (21): 4289-97. ... Marini MG, Chan K, Casula L, Kan YW, Cao A, Moi P (Jun 1997). "hMAF, a small human transcription factor that heterodimerizes ... "The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome- ...
MafF is one of the small Maf proteins, which are basic region and leucine zipper (bZIP)-type transcription factors. The HUGO ... Transcription factor MafF is a bZip Maf transcription factor protein that in humans is encoded by the MAFF gene. ... "Small Maf proteins interact with the human transcription factor TCF11/Nrf1/LCR-F1". Nucleic Acids Research. 24 (21): 4289-97. ... "Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins". Nature. 367 (6463): 568-72 ...
... is one of the small Maf proteins, which are basic region and leucine zipper (bZIP)-type transcription factors. The HUGO ... Transcription factor MafK is a bZip Maf transcription factor protein that in humans is encoded by the MAFK gene. ... "Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor". Molecular ... "Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif". Oncogene. 14 ( ...
"Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif". Oncogene. 14 ( ... "Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins". Nature. 367 (6463): 568-72 ... Transcription factor NF-E2 45 kDa subunit is a protein that in humans is encoded by the NFE2 gene. It is involved in ... Shivdasani RA, Rosenblatt MF, Zucker-Franklin D, Jackson CW, Hunt P, Saris CJ, Orkin SH (1995). "Transcription factor NF-E2 is ...
Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF2-E2 transcription factor. In mouse, ... bZIP Maf is a domain found in Maf transcription factor proteins. It contains a leucine zipper (bZIP) domain, which mediates the ... "Structural Basis of Alternative DNA Recognition by Maf Transcription Factors". Molecular and Cellular Biology. 29 (23): 6232- ... transcription factor's dimerization and DNA binding properties. The Maf extended homology region (EHR) is present at the N- ...
Transcription factor binding elements consist of TATA box binding elements, SMAD transcription factors, MAF/AP1 binding factors ... C5orf22 contains 2 globular domains and 3 small disordered regions. The molecular-weight is approximately 50 kDa. The ... January 2020). "A Proteomic Connectivity Map for Characterizing the Tumor Adaptive Response to Small Molecule Chemical ...
Nuclear factor erythroid 2-related factor 2 (NRF2), also known as nuclear factor erythroid-derived 2-like 2, is a transcription ... The Neh1 domain is a CNC-bZIP domain that allows Nrf2 to heterodimerize with small Maf proteins (MAFF, MAFG, MAFK). The Neh2 ... In the nucleus, it combines (forms a heterodimer) with one of small Maf proteins (MAFF, MAFG, MAFK) and binds to the ... NRF2 is a basic leucine zipper (bZip) transcription factor with a Cap "n" Collar (CNC) structure. NRF2 possesses seven highly ...
This condition is caused by mutations in the transcription factor MafB, or V-maf musculoaponeurotic fibrosarcoma oncogene ... The presentation is of gradual loss of the small bones in the carpus and tarsus. This may lead to joint subluxation and ... This gene encodes a basic leucine zipper (bZIP) transcription factor. The gene is located on the long arm of chromosome 20 ( ...
This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family ( ... Small Maf GRCh38: Ensembl release 89: ENSG00000156273 - Ensembl, May 2017 GRCm38: Ensembl release 89: ENSMUSG00000025612 - ... "A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/ ... Kanezaki R, Toki T, Yokoyama M, Yomogida K, Sugiyama K, Yamamoto M, Igarashi K, Ito E (Mar 2001). "Transcription factor BACH1 ...
... maf transcription factors, small MeSH D12.776.930.127.500.500.249 - maff transcription factor MeSH D12.776.930.127.500.500.500 ... mafk transcription factor MeSH D12.776.930.127.656.750 - maf transcription factors, small MeSH D12.776.930.127.656.750.249 - ... maf transcription factors, small MeSH D12.776.930.316.750.750.249 - maff transcription factor MeSH D12.776.930.316.750.750.500 ... maf transcription factors, large MeSH D12.776.930.127.500.061.500 - mafb transcription factor MeSH D12.776.930.127.500.061.625 ...
... nf-e2 transcription factor, p45 subunit MeSH D12.776.260.235.750.750 - maf transcription factors, small MeSH D12.776.260.235. ... maf transcription factors, small MeSH D12.776.260.108.500.500.249 - maff transcription factor MeSH D12.776.260.108.500.500.500 ... mafk transcription factor MeSH D12.776.260.108.656.750 - maf transcription factors, small MeSH D12.776.260.108.656.750.249 - ... maf transcription factors, large MeSH D12.776.260.108.500.061.500 - mafb transcription factor MeSH D12.776.260.108.500.061.625 ...
MAF), and heat shock transcription factor 4 (HSF4). All newborns should have screening eye examinations, including an ... Some congenital cataracts are too small to affect vision, therefore no surgery or treatment will be done. If they are ... paired-like homeodomain transcription factor 3 (PITX3), avian musculoaponeurotic fibrosarcoma ( ... Commonly, a patient with small congenital cataracts that do not affect vision will eventually be affected later in life; ...
... -associated transcription factor (MITF), located on chromosome 14q32, is associated with one form of isolated ... A key aspect of managing this condition is accounting for the small volume of the eye. The small orbit size characteristic of ... ERCC5 FADD FAM111A FNBP4 FOXL2 FRAS1 FREM1 FREM2 FZD5 GDF3 GDF6 GJA1 GRIP1 HCCS HMGB3 HMX1 IGBP1 KAT6B KMT2D LRP2 MAB21L2 MAF ... The following genes, many of which are transcription and regulatory factors, have been implicated in microphthalmia, ...
The transcription factors pancreas/duodenum homeobox protein 1 (PDX1), Neurogenin-3 (NEUROG3), and V-maf musculoaponeurotic ... Neurogenin3 is expressed in a small percentage of cells within the developing pancreas consisting of endocrine progenitor cells ... Neurogenin-3 is a pro-endocrine transcription factor that is a member of the basic helix-loop-helix (bHLH) transcription factor ... Transcription factors control gene expression by interacting with enhancer sequences. ...
Quintana's work identified important roles for the transcription factor AHR in the control of inflammation driven adaptive and ... The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27 ... Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses EAE. Proc Natl Acad Sci U S A, ... Identification of environmental factors that promote intestinal inflammation. Nature, 611(7937), 801-809 (2022). 27. Clark I.C ...
It is known that NRF3 can heterodimerize with small musculo-aponeurotic fibro-sarcoma (MAF genes) factors to bind antioxidant ... Nuclear factor (erythroid 2)-like factor 3, also known as NFE2L3 or 'NRF3', is a transcription factor that in humans is encoded ... transcription factor belonging to the Cap 'n' Collar (CNC) family of proteins. In 1989, the first CNC transcription factor ... Blank V, Andrews NC (November 1997). "The Maf transcription factors: regulators of differentiation". Trends in Biochemical ...
... a characteristic transcription factor for Th2 cells. Tr1 cells express high levels of regulatory factors, such as ... Proposed transcription biomarkers for type 1 regulatory cells differentiation are: musculoaponeurotic fibrosarcoma(c-Maf) the ... CD49b provides only little contribution to the differentiation and function of Tr1 cells. They characteristically produce high ... IL-6 and IL-21 also plays a role in differentiation as they regulate expression of transcription factors necessary for IL-10 ...
PMID 18701084.{{cite journal}}: CS1 maint: multiple names: authors list (link) "MAF bZIP transcription factor B (MAFB) [Homo ... ERICH4's highest levels of expression are within human tissue of the duodenum and small intestine, followed by the kidneys. ... 2002). "POZ domain transcription factor, FBI-1, represses transcription of ADH5/FDH by interacting with the zinc finger and ... "Transcription Factor B-Cell-Specific Activator Protein (BSAP) Is Differentially Expressed in B Cells and in Subsets of B-Cell ...
This happened when concentrations of two transcription factors named MafB and c-Maf were naturally low or were inhibited for a ... Mice exposed in vivo, to three cardiac transcription factors GMT (Gata4, Mef2c, Tbx5) and the small-molecules: SB-431542 (the ... However, brief expression of a single transcription factor, the ELT-7 GATA factor, can convert the identity of fully ... Najm FJ, Lager AM, Zaremba A, Wyatt K, Caprariello AV, Factor DC, et al. (May 2013). "Transcription factor-mediated ...
Pastorcic M, Das HK (November 2000). "Regulation of transcription of the human presenilin-1 gene by ets transcription factors ... Somatic mutations in the EP300 gene have been found in a small number of solid tumors, including cancers of the colon and ... MAF, MAML1, MEF2C, MEF2D, MYBL2, Mdm2, MyoD, MEF2A, NCOA6, NFATC2, NPAS2, P53, PAX6, PCNA, PROX1, PTMA, PPARA, PPARG, RORA, ... The p300 protein carries out its function of activating transcription by binding to transcription factors, and the ...
... coup transcription factor i MeSH D12.776.826.750.074.500 - coup transcription factor ii MeSH D12.776.826.750.350.174 - estrogen ... u2 small nuclear MeSH D12.776.664.962.500.875.615 - ribonucleoprotein, u4-u6 small nuclear MeSH D12.776.664.962.500.875.620 - ... oncogene protein v-maf MeSH D12.776.624.664.520.750.875 - oncogene proteins v-abl MeSH D12.776.624.664.520.750.882 - oncogene ... lymphoid enhancer-binding factor 1 MeSH D12.776.664.235.400.800.750 - t cell transcription factor 1 MeSH D12.776.664.962. ...
Key factors in the differentiation of Th17 cells are signal transducer and the activator of transcription 3 (Stat3) and ... In a steady state, TGF-beta and AhR ligands induce low expression of IL-22 along with high expression of AhR, c-MAF, IL-10, and ... July 2011). "Control of TH17 cells occurs in the small intestine". Nature. 475 (7357): 514-8. doi:10.1038/nature10228. PMC ... Intensive research starting in 2004 in mouse models elucidated its transcription factors and the cytokines that provoke ...
... encoding for a transcription factor. This small discrete sub-population of cells, called TFR cells (for T Follicular Regulatory ... "The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and ... Also Bcl-6 is a transcription factor identified in TFH cells, but it may have roles that extend beyond this subset, because it ... While TFH cells are found primarily in the secondary lymphoid organs, a small proportion circulate in the blood and are termed ...
Several factors could influence these data: the search strategy, the identification of relevant studies (publication bias), the ... MAF)] and the type of population (population-based or not, for example). Results of these meta-analyses need to be confirmed ... also called the alpha or small subunit or the light chain of the cytb) and gp91phox (renamed NOX2 in the 2000s) or the beta or ... suggesting that both subunits have an independent transcription process. P22phox is a transmembrane protein that contains 195 ...
Liu CH, Ren J, Liu CM, Liu PK (January 2014). "Intracellular gene transcription factor protein-guided MRI by DNA aptamers in ... Commonly, peptides, antibodies, or small ligands, and small protein domains, such as HER-2 affibodies, have been applied to ... ISBN 978-1-4160-5534-1. Aivazoglou, LU; GuimarĂ£es, JB; Link, TM; Costa, MAF; Cardoso, FN; de Mattos Lombardi Badia, B; Farias, ... A new class of gene targeting MR contrast agents has been introduced to show gene action of unique mRNA and gene transcription ...
... or entirely prevented because the proteins that make up these structures block access to the DNA by transcription factors, ... minor allele frequency (MAF) missense mutation A type of point mutation which results in a codon that codes for a different ... Because only a small population with a narrower range of genetic diversity remains afterward to pass on genes to future ... in particular through the interaction of genetic factors with environmental factors, and typically as observed in genetically ...