Current data not only indicate the presence of resident CNS macrophages (known as microglia) within the CNS, but there is also ... Kern S, Robertson SA, Mau VJ, Maddocks S (1995). "Cytokine secretion by macrophages in the rat testis". Biol. Reprod. 53 (6): ... Fujihara Y, Takato T, Hoshi K (2014). "Macrophage-inducing FasL on chondrocytes forms immune privilege in cartilage tissue ... such as macrophages and dendritic cells. These APC carry the antigen to local lymph nodes to be sampled by T cells and B cells ...

As a member of the family Arteriviridae, PRRSV has an in vivo and in vitro tropism for cells like macrophages or monocytes. ... It has been found that a 210-kDa membrane protein expressed on porcine alveolar macrophages (PAMS) allows PRRSV to attach to ... PRRSV can then infect a subpopulation of macrophages. These can then be identified by the expression of sialoadhesin PRRSV type ... "Identification of a Putative Receptor for Porcine Reproductive and Respiratory Syndrome Virus on Porcine Alveolar Macrophages ...

Macrophages known as Hofbauer cells are also present. In 1983, an Italian biologist named Giuseppe Simoni discovered a new ...

Ivins BE, Wyrick PB (November 1978). "Response of C3H/HeJ and C3H/HeN mice and their peritoneal macrophages to the toxicity of ... His earliest known published work pertained to the response of peritoneal macrophages, a type of white blood cell, to infection ... Wyrick PB, Brownridge EA, Ivins BE (March 1978). "Interaction of Chlamydia psittaci with mouse peritoneal macrophages". Infect ...

Godwin, James W.; Pinto, Alexander R.; Rosenthal, Nadia (April 24, 2013). "Macrophages are required for adult salamander limb ...

Expression is found on macrophages and dendritic cells. It can also be found at low levels in Langerhans cells and peripheral ... This in turn leads to activation of macrophages and contributes to fungal eradication. Anti-inflammatory cytokines such as IL-2 ...

It is believed that during limb generation, axolotls have a different system to regulate their internal macrophage level and ... Goodwin, James W.; Pinto, Alexander R.; Rosenthal, Nadia A. (June 4, 2013). Olson, Eric N. (ed.). "Macrophages are required for ...

Activin A also increases inflammatory cytokines in macrophages. A mutation in the gene for the activin receptor ACVR1 results ...

1985 Macrophages and their acid esterase in atherosclerosis. Pearse Prize Lecture Speech delivered 5 January 1988) Pro Roy ...

Leishmania then invades human macrophages and replicates intracellularly. A raised, red lesion develops at the site of the bite ... Histology demonstrates a mixture of chronic inflammatory cells; there can be macrophage or epitheloid granuloma. Parasite ...

Racoosin, E. L.; Swanson, J. A. (1993). "Macropinosome maturation and fusion with tubular lysosomes in macrophages". The ... "Macropinosome formation by tent pole ruffling in macrophages". J Cell Biol. 217 (11): 3873-3885. doi:10.1083/jcb.201804137. ... "M-CSF-induced macropinocytosis increases solute endocytosis but not receptor-mediated endocytosis in mouse macrophages". ...

"Cyclin D1 governs adhesion and motility of macrophages". Molecular Biology of the Cell. 14 (5): 2005-15. doi:10.1091/mbc.02-07- ...

However, macrophages, especially alveolar macrophages, usually produce far lower levels of ROS than neutrophils, and may ... Myeloid cells, including macrophages and neutrophils, are especially implicated in the respiratory burst. They are phagocytic, ... Herb M, Schramm M (February 2021). "Functions of ROS in Macrophages and Antimicrobial Immunity". Antioxidants. 10 (2): 313. doi ... Forman HJ, Torres M (December 2002). "Reactive oxygen species and cell signaling: respiratory burst in macrophage signaling". ...

These can be macrophages that secrete IL-12, which stimulates the proliferation of further CD4+ Th1 cells. CD4+ T cells secrete ... The hyper-activated macrophages secrete TNF-α which recruits multiple monocytes to the site of infection. These cells ... This response involves the interaction of T cells, monocytes, and macrophages. This reaction is caused when CD4+ Th1 cells ... An example of a tuberculosis (TB) infection that comes under control: M. tuberculosis cells are engulfed by macrophages after ...

... which is selectively required for the differentiation of monocytes to macrophages. The monocytes differentiate into macrophages ... To attract and stimulate macrophages, the cholesterol must be released from the LDL particles and oxidized, a key step in the ... On the other hand, unstable plaques are rich in macrophages and foam cells, and the extracellular matrix separating the lesion ... The actions of macrophages drive atherosclerotic plaque progression. Immunomodulation of atherosclerosis is the term for ...

Upon phagocytosis by macrophages or other immune cells, the complex may release the virus due to poor binding with the antibody ... Cells that express this receptor are represented by monocytes, macrophages, and some categories of dendritic cells and B-cells ... Chen YC, Wang SY (October 2002). "Activation of terminally differentiated human monocytes/macrophages by dengue virus: ... May 2014). "Antibody-dependent infection of human macrophages by severe acute respiratory syndrome coronavirus". Virology ...

In wound-healing in urodeles it is the quick response of anti-inflammatory macrophages which have been shown to be key to their ... In one study, it was found that limbs would not regenerate in those urodeles with depleted macrophages and instead would scar ... Godwin, James W.; Pinto, Alexander R.; Rosenthal, Nadia A. (2013-06-04). "Macrophages are required for adult salamander limb ... macrophages, monocytes, lymphocytes and also inflammatory mediators, compared with adult wounds. Physiologically, adult and ...

Kuznetsova, T.; Prange KHM; Glass, C. K.; de Winther MPJ (2020). "Transcriptional and epigenetic regulation of macrophages in ...

Meconium-laden macrophages in meconium stained fetal membranes. H&E stain. Opened uterus with cat fetus in midgestation: 1 ...

Perivillous monocyte-macrophages and histiocytic giant cells were of maternal origin. Foetal macrophages in VUE proliferate and ... The macrophages present are mainly Mac387-, followed by CD68 and HAM56+. Class 2 major histocompatibility complex (MHC) ... Macrophages, intervillous lymphocytes, multinucleated giant cells were maternal; 10.5% of intravillous CD68+ cells and 96.4% of ... The composition of inflammatory infiltrate in VUE on a cellular level is primarily macrophages and lymphocytes. The relative ...

Macrophages may restrain the contraction phase. Scientists have reported that removing the macrophages from a salamander ... Once they are in the wound site, monocytes mature into macrophages. Macrophages also secrete a number of factors such as growth ... T cells also increase the activity of macrophages. One of the roles of macrophages is to phagocytize other expended phagocytes ... suggests that the presence of macrophages actually delays wound contraction and thus the disappearance of macrophages from the ...

alpinum), Promotes Cholesterol Efflux from THP-1 Macrophages. J Nat Prod. 2016 Jun 24;79(6):1651-7. doi: 10.1021/acs.jnatprod. ...

Das PC, Roberts JD, White SL, Olden K (1995). "Activation of resident tissue-specific macrophages by swainsonine". Oncology ... Swainsonine's activity against tumors is attributed to its stimulation of macrophages. Swainsonine also has potential uses as ...

IL-1 was the name given to the macrophage product, whereas IL-2 was used to define the lymphocyte product. At the time of the ... IL-1β seems to be an amplifier of inflammation by recruitment of macrophages in the context of sterile inflammation. IL-1β is ... In contrast, monocytes and macrophages do not contain preformed IL-1α precursors, but instead rely on de novo synthesis. The IL ... It acts either independently or synergizes with IL-12, which may lead to rapid activation of the monocyte / macrophage system. ...

Usually, it is the macrophages that see an antigen first, and thus are the first cells to release IL-8 to recruit other cells. ... Interleukin 8 (IL-8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types ... In culture, a 72 amino acid peptide is the major form secreted by macrophages. There are many receptors on the surface membrane ... macrophages, mast cells, and keratinocytes) that respond to this chemokine. The chemoattractant activity of IL-8 in similar ...

... is primarily secreted by monocytes, macrophages and dendritic cells. Platelet derived growth factor is a major inducer of ... Dean RA, Cox JH, Bellac CL, Doucet A, Starr AE, Overall CM (October 2008). "Macrophage-specific metalloelastase (MMP-12) ... Administration of anti-CCL2 antibodies in a model of glomerulonephritis reduces infiltration of macrophages and T cells, ... and rescues granulocyte macrophage colony-stimulating factor suppression of osteoclast formation". The Journal of Biological ...

... tissue-bound macrophages, fibroblasts, and immature dendritic cells; vascular endothelial and smooth muscle cells; various ...

... + macrophages from human tumors also express CD68, CD163, CSF1R, and nuclear MAFB. TREM2 expressed by human monocyte ... Immunosuppressive tumor-associated macrophages (TAMs) have been characterized by expression of TREM2. TREM2 signaling leads to ... In the liver, TREM2 is expressed by several cell types, including macrophages, that respond to injury. In the intestine, TREM2 ... Monocyte-, macrophage-, and neutrophil-mediated inflammatory responses can be stimulated through G protein-linked 7- ...

... mainly macrophages. This spread can be rapid, and lethal effects may occur within a few days of challenge, affecting tissues ...

... alternative macrophage activation-associated CC chemokine-1 (AMAC-1), and macrophage inflammatory protein-4 (MIP-4). The gene ... These cells include dendritic cells, monocytes, and macrophages. Neither T-cells nor B-cells are known to produce CCL18. Its ... CCL18 is located on chromosome 17, along with many other macrophage inflammatory proteins (MIPs). The gene itself has 3 exons ... Kodelja V, Müller C, Politz O, Hakij N, Orfanos CE, Goerdt S (February 1998). "Alternative macrophage activation-associated CC- ...