Loading...
*  Tumor-associated macrophage
However, it remains unclear when M1 tumor-associated macrophages are transformed to M2 tumor-associated macrophages, but tumor ... Patients with more M1 tumor-associated macrophages displayed the opposite effect. . Macrophages are the most common cells in ... growth factors and immunosuppressive cytokines that convert trophic macrophages to tumor-associated macrophages (TAM). These ... Tumor-associated macrophages are mainly of the M2 phenotype, and seem to actively promote tumor growth. The designation of M1 ...
*  Macrophage inflammatory protein
... s (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are ... Macrophage Inflammatory Proteins at the US National Library of Medicine Medical Subject Headings (MeSH). ... Both are major factors produced by macrophages after they are stimulated with bacterial endotoxins. They are crucial for immune ... They are produced by many cells, particularly macrophages, dendritic cells, and lymphocytes. MIP-1 are best known for their ...
*  Regulatory macrophages
... (Mregs) represent one of basic macrophage population according fundamental macrophage function. These ... Coculuration of macrophages and regulatory T cells (Tregs) elicited differentiation of macrophages toward Mregs. Similar effect ... Surprisingly, Mregs resemble classically activated macrophages more than alternatively activated macrophages. It means that ... Unlike classically activated macrophages, Mregs produce high levels of anti-inflammatory cytokine interleukin 10 (IL-10) and ...
*  Adipose tissue macrophages
For example, macrophages stimulated with IL-4 and IL-13 are defined as M2a, whereas macrophages stimulated with LPS and ... Macrophages displaying M1 phenotype have been characterized by expression of F4/80, CD11c and iNOS whereas macrophages ... Adipose tissue macrophages (abbr. ATMs) comprise tissue resident macrophages present in adipose tissue. Adipose tissue apart ... M1 macrophages are microbicidal and tumoricidal, and stimulate adaptive immune response. M2 macrophages are associated with ...
*  Macrophage
HIV and the Macrophage A book on the role of macrophages in AIDS pathogenesis The role of macrophages in HIV pathogenesis ... M1 macrophages: as mentioned earlier (previously referred to as classically activated macrophages), M1 "killer" macrophages are ... Macrophages News Macrophages News provided by insciences organisation www.macrophages.com The Macrophage Community Website. ... thereby using macrophages for their own replication and causing macrophage apoptosis. Macrophages can digest more than 100 ...
*  Macrophage elastase
... (EC 3.4.24.65, metalloelastase, human macrophage metalloelastase (HME), MMP-12) is an enzyme. This enzyme ... Matrix metallopeptidase 12 Macrophage elastase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular ... Kettner, C.; Shaw, E.; White, R.; Janoff, A. (1981). "The specificity of macrophage elastase on the insulin B-chain". Biochem. ... Banda, M.J.; Werb, Z. (1981). "Mouse macrophage elastase. Purification and characterization as a metalloproteinase". Biochem. J ...
*  Macrophage polarization
... is a process by which macrophage expresses different functional programs in response to ... Granulocyte - macrophage colony stimulation factor (GM-CSF) stimulates M1 too. Alternatively activated macrophages cover a ... "Macrophage polarization: tumour-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes." Trends in ... M2a macrophages are connected with Th2 immune response. Th2 cells, eosinophils, basophils and macrophages themselves produce IL ...
*  Alveolar macrophage
An alveolar macrophage (or dust cell) is a type of macrophage found in the pulmonary alveolus, near the pneumocytes, but ... Alveolar macrophages are also involved in the phagocytosis of apoptotic and necrotic cells that have undergone cell-death. They ... Alveolar macrophages are frequently seen to contain granules of exogenous material such as particulate carbon that they have ... IFN-γ induces both an increased affinity of the NADPH oxidase for NADPH in macrophages, as well as an increased rate of gene ...
*  Macrophage (ecology)
The terms "macrophage" and "microphage" are used in ecology to describe heterotrophs that consume food in two different ways. ... Both macrophages and microphages "ingest solid food and may process it through some sort of alimentary canal." However, a ... The terms "macrophage" and "microphage" were originally used in this sense by Jordan and Hirsch (1927; cited in Yonge 1928). ... Although they have been used in ecology texts as recently as 2002, the terms macrophage and microphage today are primarily used ...
*  Tingible body macrophage
A tingible body macrophage is a type of macrophage predominantly found in germinal centers, containing many phagocytized, ... Smith JP, Burton GF, Tew JG, Szakal AK (1998). "Tingible body macrophages in regulation of germinal center reactions". ... Horst Ibelgaufts' COPE: Cytokines & Cells Online Pathfinder Encyclopaedia > tingible body macrophages Retrieved on June 27, ... Tingible body macrophages contain condensed chromatin fragments. It is thought that they may play a role in downregulating the ...
*  Macrophage-activating factor
The phrase 'alternatively activated macrophage' is used to refer to M2 macrophages. Regulatory macrophages do not fit into the ... Analysis of the macrophage population and signaling in a tumor may provide useful clinical data. Macrophages have been ... A macrophage-activating factor (MAF) is a lymphokine or other receptor based signal that primes macrophages towards ... Macrophages inherently display tissue and environment-dependent plasticity. In addition, the phenotypes of the macrophages in a ...
*  Macrophage activation syndrome
Macrophage-activation syndrome (MAS) is a severe, potentially life-threatening, complication of several chronic rheumatic ... In addition, other specific markers of macrophage activation (e.g. soluble CD163), and lymphocyte activation (e.g. soluble IL-2 ... Badugu, Srinivasarao (2010). "MACROPHAGE ACTIVATIONS SYNDROME, AN IMPORTANT DIFFERENTIAL DIAGNOSIS FOR SEPTIC SHOCK". Critical ... There is uncontrolled activation and proliferation of macrophages, and T lymphocytes, with a marked increase in circulating ...
*  Pancreatic islet macrophage
... showing that islet resident macrophages promote beta cell proliferation suggest that islet macrophages are likely important ... Islet resident macrophages depend on the expression of colony stimulating factor (CSF1). Knockout mice for the CSF-1 gene cause ... As opposed to macrophages in the islet stroma (tissue), whose developmental origin is from the yolk sac (primitive ... Islet resident macrophages are uniquely found within the endocrine tissue (islet), while nearby in the nearby acinar tissue, ...
*  Macrophage-capping protein
... (CAPG) also known as actin regulatory protein CAP-G is a protein that in humans is encoded by the ... Southwick FS (1995). "Gain-of-function mutations conferring actin-severing activity to human macrophage cap G". J. Biol. Chem. ... A unique member of the gelsolin/villin family expressed primarily in macrophages". J Biol Chem. 267 (23): 16545-52. PMID ... "Molecular cloning of human macrophage capping protein cDNA. ...
*  Macrophage-1 antigen
... (or integrin αMβ2 or macrophage integrin or Mac-1) is a complement receptor ("CR3") consisting of CD11b ( ... CR3 CD11b/CD18 Macrophage 1 antigen (Mac-1) Macrophage Todd R (1996). "The continuing saga of complement receptor type 3 (CR3 ... Macrophage-1 antigen at the US National Library of Medicine Medical Subject Headings (MeSH). ... and mononuclear phagocytes like macrophages. CR3 is a pattern recognition receptor, capable of recognizing and binding to many ...
*  Bone marrow-derived macrophage
Bone-marrow-derived macrophage (BMDM) refers to macrophage cells that are generated in a research laboratory from mammalian ... Undifferentiated bone marrow cells are cultured in the presence of macrophage colony-stimulating factor (M-CSF; CSF1). M-CSF is ... Weischenfeldt, Joachim; Porse, Bo (2008-12-01). "Bone Marrow-Derived Macrophages (BMM): Isolation and Applications". Cold ...
*  Macrophage colony-stimulating factor
... macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating ... driving proliferation of a pro-inflammatory macrophage phenotype. Macrophage colony-stimulating factor has been shown to ... Macrophage Colony-Stimulating Factor at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ... The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor ( ...
*  Macrophage migration inhibitory factor
... has been reported to interact with: BNIPL, CD74, COPS5, CXCR4, and RPS19. MIF is an ... Chen PF, Luo YL, Wang W, Wang JX, Lai WY, Hu SM, Cheng KF, Al-Abed Y (2010). "ISO-1, a macrophage migration inhibitory factor ... Macrophage migration inhibitory factor is also a potential drug target for sepsis, rheumatoid arthritis, and cancer. It has ... Takahashi K, Koga K, Linge HM, Zhang Y, Lin X, Metz CN, Al-Abed Y, Ojamaa K, Miller EJ (May 2009). "Macrophage CD74 contributes ...
*  Granulocyte-macrophage colony-stimulating factor
In macrophages, it has also been shown to signal via STAT3. The cytokine activates macrophages to inhibit fungal survival. It ... "Granulocyte macrophage-colony stimulating factor induced Zn sequestration enhances macrophage superoxide and limits ... Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric ... Thus, it is part of the immune/inflammatory cascade, by which activation of a small number of macrophages can rapidly lead to ...
*  Macrophage migration inhibitory factor domain
... is an evolutionary conserved protein domain. Macrophage migration inhibitory ... MIF is released from T-cells and macrophages, and acts within the neuroendocrine system. MIF is capable of tautomerase activity ... Matsunaga J, Sinha D, Solano F, Santis C, Wistow G, Hearing V (November 1999). "Macrophage migration inhibitory factor (MIF)-- ... Donn RP, Ray DW (July 2004). "Macrophage migration inhibitory factor: molecular, cellular and genetic aspects of a key ...
*  Natural Resistance-Associated Macrophage Proteins
... (NRAMPs) are members of the Metal Ion (Mn2+-iron) Transporter (NRAMP) Family ... In contrast to the widely expressed NRAMP2, NRAMP1 is expressed primarily in macrophages and monocytes and appears to have a ... macrophage proteins because one of the animal homologues plays a role in resistance to intracellular bacterial pathogens such ... for Mn2+ or some other metal prevents the generation of reactive oxygenic and nitrogenic compounds that are used by macrophage ...
*  Granulocyte-macrophage colony-stimulating factor receptor
The granulocyte-macrophage colony-stimulating factor receptor also known as CD116 (Cluster of Differentiation 116), is a ... Gearing DP, King JA, Gough NM, Nicola NA (Dec 1989). "Expression cloning of a receptor for human granulocyte-macrophage colony- ... Lia F, Rajotte D, Clark SC, Hoang T (Nov 1996). "A dominant negative granulocyte-macrophage colony-stimulating factor receptor ... Doyle SE, Gasson JC (Aug 1998). "Characterization of the role of the human granulocyte-macrophage colony-stimulating factor ...
*  Goblet cell
"Pulmonary macrophages". European Respiratory Journal. 7 (9): 1678-1689. doi:10.1183/09031936.94.07091678. PMID 7995399. "goblet ...
*  Innate lymphoid cell
M1 macrophages. ILC1 also recruit DC and cytotoxic T cells. On the other hand, IFN g and TNF a play important role in induction ...
*  Necrosis
... and peritoneal macrophages. Pathogen-induced necrosis programs in cells with immunological barriers (intestinal mucosa) may ...