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*  Macrophage-1 antigen
... (or integrin αMβ2 or macrophage integrin or Mac-1) is a complement receptor ("CR3") consisting of CD11b ( ... CR3 CD11b/CD18 Macrophage 1 antigen (Mac-1) Macrophage Todd R (1996). "The continuing saga of complement receptor type 3 (CR3 ... Macrophage-1 antigen at the US National Library of Medicine Medical Subject Headings (MeSH). ... and mononuclear phagocytes like macrophages. CR3 is a pattern recognition receptor, capable of recognizing and binding to many ...
*  Intercellular adhesion molecule
The ICAM family consists of five members, designated ICAM-1 to ICAM-5. They are known to bind to leucocyte integrins CD11/CD18 ... In molecular biology, intercellular adhesion molecules (ICAMs) and vascular cell adhesion molecule-1 (VCAM-1) are part of the ... Mammalian intercellular adhesion molecules include: ICAM-1 ICAM2 ICAM3 ICAM4 ICAM5 Gahmberg CG, Tolvanen M, Kotovuori P (April ... such as LFA-1 and Macrophage-1 antigen, during inflammation and in immune responses. In addition, ICAMs may exist in soluble ...
*  Integrin alpha M
Integrin alphaM at the US National Library of Medicine Medical Subject Headings (MeSH) Mouse CD Antigen Chart Human CD Antigen ... In histopathology, immunohistochemistry with antibodies against CD11B is frequently used to identify macrophages and microglia ... also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A, and cluster of ... macrophages, and natural killer cells. It mediates inflammation by regulating leukocyte adhesion and migration and has been ...
*  CD11
... present on macrophages that is also called Macrophage-1 antigen (CR3) and αmβ2 integrin. CD11c/CD18 also called complement ... For example, LFA1 (CD11a/CD18) short representation of Lymphocyte Function-associated Antigen 1, also called αLβ2 integrin Mac1 ...
*  CD18
... antigen at the US National Library of Medicine Medical Subject Headings (MeSH) ITGB2 Info with links in the Cell Migration ... Macrophage-1 antigen (paired with CD11b) Integrin alphaXbeta2 (paired with CD11c) Integrin alphaDbeta2 (paired with CD11d) The ... Huang C, Springer TA (August 1995). "A binding interface on the I domain of lymphocyte function-associated antigen-1 (LFA-1) ... 16 (1): R42. doi:10.1186/ar4471. Wixler V, Geerts D, Laplantine E, Westhoff D, Smyth N, Aumailley M, Sonnenberg A, Paulsson M ( ...
*  RTX toxin
In host cells expressing the CD11b/CD18 integrin receptor (macrophage-1 antigen, αMβ2 integrin), CyaA binds the αMβ2 integrin ... haemolytica interacts only with alveolar macrophages, neutrophils, and lymphocytes of ruminants and is believed to promote ... 1778 (1): 260-269. doi:10.1016/j.bbamem.2007.09.026. ISSN 0006-3002. PMID 17976530. Frey J (November 2011). "The role of RTX ... Members of the RTX superfamily (RTX (TC# 1.C.11); HrpZ (TC# 1.C.56) and CCT (TC# 1.C.57)) contain repeat sequences that are ...
*  Alveolar macrophage
"Downregulation of the Antigen Presenting Cell Function(s) of Pulmonary Dendritic Cells in Vivo by Resident Alveolar Macrophages ... An alveolar macrophage (or dust cell) is a type of macrophage found in the pulmonary alveolus, near the pneumocytes, but ... Alveolar macrophages are also involved in the phagocytosis of apoptotic and necrotic cells that have undergone cell-death. They ... Alveolar macrophages are frequently seen to contain granules of exogenous material such as particulate carbon that they have ...
*  CR3
... or CR-3 may refer to: Macrophage-1 antigen, an immunological cell surface receptor for a complement component CR3, an x86 ...
*  List of MeSH codes (D12.776.543)
... antigens, cd46 MeSH D12.776.543.750.705.833.249 -- integrin alphaxbeta2 MeSH D12.776.543.750.705.833.500 -- macrophage-1 ... antigen, b-cell MeSH D12.776.543.750.705.816.821.500 -- antigens, cd79 MeSH D12.776.543.750.705.816.824 -- receptors, antigen, ... antigens, cd22 MeSH D12.776.543.550.200.124 -- antigens, cd24 MeSH D12.776.543.550.200.131 -- antigens, cd31 MeSH D12.776. ... antigens, cd27 MeSH D12.776.543.750.705.852.760.072 -- antigens, cd30 MeSH D12.776.543.750.705.852.760.097 -- antigens, cd40 ...
*  DNA vaccination
After IM and ID injections, dendritic cells present antigen in the draining lymph node and transfected macrophages have been ... The antigen-presenting cell then travels to the lymph nodes and presents the antigen peptide and costimulatory molecule ... This is true for intracellular and plasma membrane-bound antigens, but not for secreted antigens, which seem to generate TH2 ... Secreted or plasma membrane-bound antigens are more effective at inducing antibody responses than cytosolic antigens, while ...
*  Outline of immunology
Spleen Metallophilic macrophage - Spleen Red pulp macrophage - Splenic red pulp Tingible body macrophage (White pulp macrophage ... Antigen Antigenicity Immunogen Superantigen Allergen Hapten Epitope Linear Conformational Mimotope Tumor antigen Antigen- ... Adipose tissue macrophages Kupffer cell - Liver Alveolar macrophage (Dust cell) - Lung Langerhans cell - Skin Dermal macrophage ... CNS Perivascular macrophage Meningeal macrophage - Meninges Hofbauer cell - Placenta Osteoclasts - Bone Bone marrow macrophage ...
*  Neuroinflammation
ED1 macrophage antigen, CD4, and leukocyte common antigen. These activated microglia decrease the ability for neurons to ... A decreased population of M2 macrophages and an increased population of M1 macrophages is associated with chronic inflammation ... Wang X, Cao K, Sun X, Chen Y, Duan Z, Sun L, Guo L, Bai P, Sun D, Fan J, He X, Young W, Ren Y (April 2015). "Macrophages in ... Cells involved in the innate and adaptive immune responses, such as macrophages, T Cells, and B Cells, may then enter into the ...
*  CPM (gene)
Rehli M, Krause SW, Andreesen R (2000). "The membrane-bound ectopeptidase CPM as a marker of macrophage maturation in vitro and ... Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at ... 258 (1): 204-10. doi:10.1006/bbrc.1999.0619. PMID 10222261. Bektas A, Hughes JN, Warram JH, et al. (2001). "Type 2 diabetes ... 50 (1): 204-8. doi:10.2337/diabetes.50.1.204. PMID 11147789. Suzuki Y, Taira H, Tsunoda T, et al. (2001). "Diverse ...
*  Major histocompatibility complex, class II, DQ alpha 1
Class II molecules are expressed in antigen-presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha ... Marsh SG, Bodmer JG (1993). "HLA class II nucleotide sequences, 1992". Tissue Antigens. 40 (5): 229-43. doi:10.1111/j.1399- ... 1991). "Interaction of CD4 with HLA class II antigens and HIV gp120". Immunogenetics. 34 (2): 121-8. doi:10.1007/BF00211424. ... Major histocompatibility complex Human leukocyte antigen HLA-DQ ENSG00000196735, ENSG00000206305, ENSG00000225890, ...
*  Major histocompatibility complex, class II, DP alpha 1
Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha ... Major histocompatibility complex Human leukocyte antigen HLA-DP "Entrez Gene: HLA-DPA1 major histocompatibility complex, class ... Major histocompatibility complex, class II, DP alpha 1, also known as HLA-DPA1, is a human gene. The protein encoded by this ... II, DP alpha 1". This article incorporates text from the United States National Library of Medicine, which is in the public ...
*  CD68
"MACROPHAGE ANTIGEN CD68; CD68". omim.org. Retrieved 16 September 2017. Leong, Anthony S-Y; Cooper, Kumarason; Leong, F Joel W-M ... Damoiseaux, JG; Döpp, EA; Calame, W; Chao, D; MacPherson, GG; Dijkstra, CD (1994). "Rat macrophage lysosomal membrane antigen ... In this species, it is expressed in most macrophage populations and thus ED1 is commonly used as a pan-macrophage marker. ... by circulating macrophages, and by tissue macrophages (e.g., Kupffer cells, microglia). Human CD68 is a transmembrane ...
*  ICAM-1
Katz FE, Parkar M, Stanley K, Murray LJ, Clark EA, Greaves MF (Jan 1985). "Chromosome mapping of cell membrane antigens ... macrophages, and lymphocytes. ICAM-1 is a ligand for LFA-1 (integrin), a receptor found on leukocytes. When activated, ... Huang C, Springer TA (Aug 1995). "A binding interface on the I domain of lymphocyte function-associated antigen-1 (LFA-1) ... leukocyte function associated antigen-1 (LFA-1), and fibrinogen. These three proteins are generally expressed on endothelial ...
*  Gordon MacPherson
"Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1. (1994) Immunology, 83 (1), pp. 140-147. Cited ... Liu, L.M., MacPherson, G.G. "Antigen acquisition by dendritic cells: Intestinal dendritic cells acquire antigen administered ... He is recognized for his "pioneering work" on the modulation of the adaptive immune response by sub-populations of antigen- ... Relationship between macrophages, Lagerhans cells, reticular cells, and dendritic cells in lymphoid and hematopoietic organs" ( ...
*  CLEC10A
The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct ... "Molecular cloning and expression of cDNA encoding human macrophage C-type lectin. Its unique carbohydrate binding specificity ... for Tn antigen". J. Immunol. 156 (1): 128-35. PMID 8598452. "Entrez Gene: CLEC10A C-type lectin domain family 10, member A". ... 2009). "Single nucleotide polymorphism of TAG-1 influences IVIg responsiveness of Japanese patients with CIDP". Neurology. 73 ( ...
*  Oncolytic virus
Another way to help oncolytic viruses reach cancer growths after intravenous injection, is to hide them inside macrophages (a ... Efforts to induce this phenomenon have used cancer vaccines (derived from cancer cells or selected cancer antigens), or direct ... Abbreviations: 5-FC, 5-fluorocytosine; GM-CSF, granulocyte macrophage colony-stimulating factor; IFNγ, interferon γ; MAGEA3, ... melanoma antigen family A3; s.c., sub cutem.*initiated between 2014, March 1 and 2015, October 31. Talimogene laherparepvec was ...
*  Lymphocyte function-associated antigen 1
... macrophages, neutrophils and NK cells and is involved in recruitment to the site of infection. It binds to ICAM-1 on antigen- ... Lymphocyte function-associated antigen 1 (LFA-1) is found on all T-cells and also on B-cells, ... "Lymphocyte function-associated antigen 1 (LFA-1): a surface antigen distinct from Lyt-2,3 that participates in T lymphocyte- ... LFA-1 is part of the family of leukocyte integrins that are recognised by their common β-chains (β2, CD18). LFA-1 also has a ...
*  Brigitte Askonas
She went on to investigate macrophages and their role in antigen presentation (1962-1968). From 1963-66 she studied the fate of ... Askonas, B.A.; Rhodes, J.M. (1965). "Immunogenicity of Antigen-Containing Ribonucleic Acid Preparations from Macrophages". ... antigen in relation to antibody formation and later continued her study of B cells (1965-1970). Obituary, The Daily Telegraph, ... Askonasi, Brigitte A. (1 April 1990). "From Protein Synthesis to Antibody formation and Cellular Immunity: A Personal View". ...
*  CD163
Law SK, Micklem KJ, Shaw JM, Zhang XP, Dong Y, Willis AC, Mason DY (1993). "A new macrophage differentiation antigen which is a ... It has also been shown to mark cells of monocyte/macrophage lineage. The receptor was discovered in 1987. The molecular size is ... PMID 16189277 Lau SK, Chu PG, Weiss LM (2004). "CD163: a specific marker of macrophages in paraffin-embedded tissues". Am. J. ... sCD163 is upregulated in a large range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage ...
*  Macrophage
The antigen presentation on the surface of infected macrophages (in the context of MHC class II) in a lymph node stimulates TH1 ... HIV and the Macrophage A book on the role of macrophages in AIDS pathogenesis The role of macrophages in HIV pathogenesis ... M1 macrophages: as mentioned earlier (previously referred to as classically activated macrophages), M1 "killer" macrophages are ... Macrophages News Macrophages News provided by insciences organisation www.macrophages.com The Macrophage Community Website. ...
*  Testicular immunology
Macrophages are directly involved in the fight against invading micro-organisms as well as being antigen-presenting cells which ... Pöllänen P, Maddocks S (1988). "Macrophages, lymphocytes and MHC II antigen in the ram and the rat testis". J Reprod Fertil. 82 ... Pöllänen P, Niemi M (1987). "Immunohistochemical identification of macrophages, lymphoid cells and HLA antigens in the human ... They originate from blood monocytes which move into the testis then mature into macrophages. In the rat, testicular macrophages ...
*  LILRA3
... macrophages, and dendritic cells involved in antigen processing". The Journal of Experimental Medicine. 185 (10): 1743-51. doi: ... however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted ... Leukocyte immunoglobulin-like receptor subfamily A member 3 (LILR-A3) also known as CD85 antigen-like family member E (CD85e), ... doi:10.1007/s00251-003-0561-1. PMID 12750859. Zhang Z, Henzel WJ (October 2004). "Signal peptide prediction based on analysis ...