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*  Polymer sponge
... blood transfusion, T lymphocyte modification and the similar techniques. The scope of polymer sponge in this field is still in ...
*  List of MeSH codes (E02)
... leukocyte transfusion MeSH E02.095.135.140.425.445 --- lymphocyte transfusion MeSH E02.095.135.140.650 --- platelet transfusion ... blood transfusion, intrauterine MeSH E02.095.135.469 --- exchange transfusion, whole blood MeSH E02.095.135.750 --- plasma ... File "2006 MeSH Trees".) MeSH E02.095.135.140 --- blood component transfusion MeSH E02.095.135.140.275 --- erythrocyte ... lymphocyte depletion MeSH E02.095.520.450.800 --- transplantation conditioning MeSH E02.095.520.750 --- radioimmunotherapy MeSH ...
*  Transfusion-related immunomodulation
Treatment of recurrent spontaneous abortion by immunization with paternal lymphocytes: results of a controlled trial. Am J ... Transfusion medicine. First of two parts--blood transfusion. N Engl J Med. 1999 Feb 11;340(6):438-47. Review. doi:10.1056/ ... Transfusion-related immunomodulation refers to the transient depression of the immune system following transfusion of blood ... However, other studies have not shown these differences and the degree of impact transfusion has on infection and tumor ...
*  Geoffrey Tovey
He was also president of the International Society of Blood Transfusion. He was Consultant Adviser on Blood Transfusion at the ... He performed early work on the typing of red cells and their antigens, white blood cells (Human Lymphocyte Antigens or HLAs), ... In that year he was appointed Director of the South West Regional Blood Transfusion Service. It was in the evening of J D R ... During the Second World War, he joined the Royal Army Medical Corps and was posted to the Army Blood Transfusion Service from ...
*  Jeanne Lusher
Diminished helper/suppressor lymphocyte ratios and natural killer activity in recipients of repeated blood transfusions. Blood ... Specifically, helper/suppressor lymphocyte ratios were diminished, a hallmark of acquired immunodeficiency syndrome (AIDS) in ... The available treatment for hemophilia at the time included transfusion of large volumes of fresh frozen plasma to replenish ... In the 1980s, Lusher and her colleagues recognized an immune dysfunction in patients who received repeated blood transfusions, ...
*  Major histocompatibility complex
... perhaps by previous blood transfusions (donor tissue that includes lymphocytes expressing HLA molecules), by anti-HLA generated ... T lymphocytes can detect a peptide displayed at 0.1%-1% of the MHC molecules. In their development in the thymus, T lymphocytes ... T lymphocytes of the recipient take the incompatible peptide-binding groove as nonself antigen. The T lymphocytes' recognition ... T lymphocytes are selected for their TCR incapacity to recognize self antigens, yet T lymphocytes can react against the donor ...
*  Transfusion-associated graft versus host disease
... is a rare complication of blood transfusion, in which the donor T lymphocytes mount an immune response against the recipient's ... "Complications of Transfusion: Transfusion Medicine: Merck Manual Professional". Retrieved 2009-02-09. Anwar M, Bhatti F (2003 ... and established by HLA analysis of the circulating lymphocytes. This testing can identify circulating lymphocytes with a ... Donor lymphocytes are usually identified as foreign and destroyed by the recipient's immune system. However, in situations ...
*  Misconceptions about HIV/AIDS
"Low CD4+ counts in a study of transfusion safety. The Transfusion Safety Study Group". N. Engl. J. Med. 328 (6): 441-442. doi: ... Infected lymphocytes express the Fas ligand, a cell-surface protein that triggers the death of neighboring uninfected T-cells ... The Transfusion Safety Study Group". Blood. 82 (4): 1351-7. PMID 8353293. Aledort, L.M.; Operskalski, E.A.; Dietrich, S.L.; ... Transfusion Safety Study Group". Blood. 84 (5): 1666-71. PMID 7915149. Goedert, JJ; Kessler, CM; Aledort, LM; Biggar, RJ; Andes ...
*  Blood transfusion
Allogeneic blood transfusion, through five major mechanisms including the lymphocyte-T set, myeloid-derived suppressor cells ( ... Blood transfusions fell into obscurity for the next 150 years. The science of blood transfusion dates to the first decade of ... Post-transfusion purpura is a complication that occurs after transfusion of platelets and is associated with the presence of ... Transfusions with large amounts of red blood cells, whether due to severe hemorrhaging and/or transfusion inefficacy (see above ...
*  Immunotherapy
Upon transfusion into the person, these activated cells present the antigen to the effector lymphocytes (CD4+ helper T cells, ... The extraction of G-CSF lymphocytes from the blood and expanding in vitro against a tumour antigen before reinjecting the cells ... Adoptive cell transfer in vitro cultivates autologous, extracted T cells for later transfusion. The T cells may already target ... Kida K, Isozumi R, Ito M (December 2000). "Killing of human Herpes virus 6-infected cells by lymphocytes cultured with ...
*  Experiments in immunology
In studying lymphocytes, the first step is to isolate them so that they can be studied in vitro. Lymphocytes can be isolated ... Hematopoietic cells are killed by ionizing radiation, and the hematopoietic system is replaced by transfusion of donor bone ... Upon isolation, the lymphocytes are characterized in terms of specificity, frequency and function. Frequently used assays ... Experiments Immunology Antibodies Lymphocyte Murphy, K., P. Travers, et al. (2008). Janeway's Immunobiology. New York and ...
*  Graft-versus-host disease
Transfusion-associated GvHD is rare in modern medicine. It is almost entirely preventable by controlled irradiation of blood ... products to inactivate the white blood cells (including lymphocytes) within. Thymus transplantation may be said to be able to ... GvHD can also occur after a blood transfusion if the blood products used have not been irradiated or treated with an approved ... Transfusion. 37 (10): 1084-92. doi:10.1046/j.1537-2995.1997.371098016450.x. PMID 9354830. Xia, G; Goebels, J; Rutgeerts, O; ...
*  Georges Mathé
Lymphocytes, Macrophages and Cancers, Springer Verlag Heidelberg, 1976; Mathé and Rappaport, Neoplastic diseases of ... Bone marrow transplantation and leucocyte transfusion, Springfield, 1971, Thomas; Mathé, Larysse and Kenis, Cancer chemotherapy ...
*  Omar Fakhri
He called these lymphocytes "co-optable lymphocytes." As other scientists began to explore this phenomenon these lymphocytes ... To his surprise, he found none, suggesting that transfusion might be possible. He then carried out transfusions of macrophages ... He found that when lymphocytes were mixed with cancerous cells in the presence of antibodies the lymphocytes encircled the ... Until the late 1960s, lymphocytes and antibodies were thought to act separately and have different functions. While working on ...
*  Alloimmunity
Activation of T-lymphocytes T-lymphocytes are fully activated under two conditions: T-lymphocytes must recognize complex MHC- ... A failure of cross-matching can allow donor blood of an incompatible blood group to be transfused, resulting in a transfusion ... B-lymphocytes, NK cells and cytokines also play a role in it. Cellular rejection - CD4+ and CD8+ T-lymphocytes, NK cells ... of CD8+ T-lymphocytes recognize these peptides when form the complex with MHC class I molecules and TCR of CD4+ T-lymphocytes ...
*  Transplant rejection
Lymphocytes include two classes that enact adaptive immunity, also called specific immunity. Lymphocytes of specific immunity T ... This is typical of minor blood group exposure (e.g. Kell) following allogenic blood transfusion or trauma during pregnancy. At ... There is a risk of graft-versus-host disease (GVHD), however, whereby mature lymphocytes entering with marrow recognize the new ... Alloreactive killer T cells, also called cytotoxic T lymphocytes (CTLs), have CD8 receptors that dock to the transplanted ...
*  Hepatitis C
Blood transfusion, transfusion of blood products, or organ transplants without HCV screening carry significant risks of ... In addition to replicating in the liver the virus can multiply in lymphocytes. The primary route of transmission in the ... and transfusions. Using blood screening, the risk from a transfusion is less than one per two million. It may also be spread ... The typical changes seen are lymphocytes within the parenchyma, lymphoid follicles in portal triad, and changes to the bile ...
*  Autologous immune enhancement therapy
Immediately after a cancer cell is recognized, the Lymphocytes and/or the NK cells attack the cancer cell to kill it. When the ... Journal of Hematology and Blood Transfusion. doi:10.1007/s12288-013-0327-3. Explore 'Killer Cell' Treatment to Cure rare ... with an aim of inducing the lymphocytes which will carry their activity of destroying the tumour cells. Thereafter the adverse ... The immune system is a complex network of cells and organs comprising lymphocytes, macrophages, Dendritic cells, Natural Killer ...
*  Cecil Kelley criticality accident
Numerous blood transfusions had no lasting helpful effect: 35 hours after his initial exposure and after a final bout of ... Within six hours his lymphocytes were all but gone. A bone biopsy performed 24 hours after the incident produced bone marrow ...
*  Induced stem cells
RBC transfusion is necessary for many patients. However, to date the supply of RBCs remains labile. In addition, transfusion ... iNKT cells act as innate T lymphocytes and serve as a bridge between the innate and acquired immune systems. They augment anti- ... Transfusion of in vitro-generated RBCs or erythroblasts does not sufficiently protect against tumor formation. The aryl ... See also overview A specialised type of white blood cell, known as cytotoxic T lymphocytes (CTLs), are produced by the immune ...
*  Chronic lymphocytic leukemia
Most often the lymphocyte count is greater than 5000 cells per microliter (µl) of blood, but can be much higher. The presence ... Blood transfusions have been ruled out as a risk factor. CLL is usually first suspected by a diagnosis of lymphocytosis, an ... Normal B lymphocytes consist of a stew of different antibody-producing cells, resulting in a mixture of both kappa- and lambda- ... CLL results in the build up of B cell lymphocytes in the bone marrow, lymph nodes, and blood. These cells do not function well ...
*  Microchimerism
Lymphocytes also influence the development of persisting fetomaternal microchimerism since natural killer cells compose about ... Reed W, Lee TH, Norris PJ, Utter GH, Busch MP (2007). "Transfusion-associated microchimerism: a new complication of blood ... Microchimerism had also been shown to exist after blood transfusions to a severely immunocompromised population of patients who ... 2006). "Maternal microchimerism in healthy adults in lymphocytes, monocyte/macrophages and NK cells". Lab Invest. 86 (11): 1185 ...
*  Influenza treatment
Human T lymphocytes can be expanded in vitro using beads holding specific antigens to activate the cells and stimulate growth. ... An alternative to vaccination used in the 1918 flu pandemic was the direct transfusion of blood, plasma, or serum from ...
*  Selective immunoglobulin A deficiency
2058 Litzman J, Vlková M, Pikulová Z, Stikarovská D, Lokaj J (February 2007). "T and B lymphocyte subpopulations and activation ... Patients with Selective IgA deficiency are at risk of anaphylaxis from blood transfusions. These patients should receive IgA ... They may present with severe reactions including anaphylaxis to blood transfusions or intravenous immunoglobulin due to the ... it does not present the same lymphocyte subpopulation abnormalities. IgA-deficient patients may progress to ...
*  Chang Yi Wang
Activation of autologous reactive helpter T lymphocytes for differentiation of human B lymphocytes. J Immunol 1981: 126:2483. ... Transfusion 1990; 30S: 513. 28. Kao HT, Gregerson PK, Tang JC, Takahashi T, Wang CY and Silver J, Molecular analysis of HLA ... Human lymphocyte bearing 1a-like antigens [now termed HLA-DK or class 1 MHC antigen]: Absence in patients with infantile ... Patterns and prevalence of hepatitis type C infection in post-transfusion non-A, non-B hepatitis. J Inf Dis 1993; 167: 1296- ...
*  Edmund Klein
... and was amongst the first to clinically explore the use of lymphocytes to help cancer patients, earning him the nickname "the ... greatly increasing the efficiency of the entire transfusion process; now three people could benefit from a single donor instead ...