*Mixed lymphocyte reaction

... (MLR) is a test used by pharmaceutical and biotech organizations to show the safety of a drug or ... A reaction between leukocytes in mixed peripheral blood cultures. Fed. Proc. 22:4281. 3. Bach, F.H. and K. Hirschhorn. 1964. ... "Why are Mixed Lymphocyte Reactions Performed?". Retrieved 7 January 2017. 1. Meo, T.: The MLR test in the mouse. 1979. In ... Two way mixed lymphocyte reaction) will replicate in the presence of the Responder cells, therefore for a One way mixed ...

*Fritz Bach

The mixed lymphocyte culture (MLC) test as it was called, was an important step in transplant science. It was based on study of ... One of his main achievements was the development of the mixed lymphocyte culture (MLC) test, which furthered research on ... By 1975 Bach had improved his technique so that the test would not take days anymore, but hours. This led to the possibility to ... Bach's major contribution to transplant science was the invention of a technique to mix cells from donor material to cells from ...

*List of MeSH codes (E01)

... lymphocyte culture test, mixed MeSH E01.450.495.400 --- immune adherence reaction MeSH E01.450.495.410 --- immunoassay MeSH ... intradermal tests MeSH E01.370.750.300.400 --- kveim test MeSH E01.370.750.300.750 --- skin test end-point titration MeSH ... intradermal tests MeSH E01.450.495.750.300.540 --- kveim test MeSH E01.450.495.750.300.750 --- skin test end-point titration ... lactose tolerance test MeSH E01.370.372.460 --- liver function tests MeSH E01.370.372.600 --- pancreatic function tests MeSH ...

*Tissue typing

One technique of tissue typing, "mixed leukocyte reaction", is performed by culturing lymphocytes from the donor together with ... Tissue typing is a procedure in which the tissues of a prospective donor and recipient are tested for compatibility prior to ... In this technique a donor's blood cells are MHC typed by mixing them with serum containing the anti-HLA antibodies. If the ...

*Bovine malignant catarrhal fever

... lesions of MCF are lymphocytic arteritis with necrosis of the blood vessel wall and the presence of large T lymphocytes mixed ... Developing a vaccine has been difficult because the virus will not grow in cell culture and until recently it was not known why ... OIE Manual of Diagnostic Tests and Vaccines for terrestrial Animal, fifth ed., France. pp. 570-579. Carter, G.R.; Flores, E.F ... This phenomenon explains why it has been impossible to grow the virus on any one particular cell culture. Because the virus is ...

*Jan Klein

... proliferation of lymphocytes in an in vitro culture challenged with H2-incompatible stimulating cell (the so-called mixed ... The tests revealed that closely related species such as M. domesticus and M. musculus, the many haplochromine fish species in ... Lymphocytes isolated from the high responder proliferated to a much higher degree than those isolated from a low responder ... In this set-up the question reduced itself to: Are the T lymphocytes or the APCs responsible for the difference in ...

*Scarring hair loss

... lymphocytes, neutrophils, or mixed inflammatory cells. Treatment strategies are different for each subtype and detailed ... A hair "pull test" is performed to see if growing, or anagen, where hairs are pulled out easily. The pulled hairs are mounted ... In addition, if pustules are present, cultures are taken to identify which microbes, if any, may be contributing to the ... Treatment of the mixed group of cicatricial alopecias (folliculitis keloidalis) may include antimicrobials, isotretinoin, and ...

*Adoptive cell transfer

They then produce pure cultures of lymphocytes that can be tested for reactivity against other tumors, in coculture assays. ... harboring rearrangement of the mixed lineage leukemia (MLL). The transfer of regulatory T cells has been used to treat Type 1 ... "Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapy". Journal of ... "Clinical responses in a phase II study using adoptive transfer of short-term cultured tumor infiltration lymphocytes in ...

*Saponin

Froth Test Uses plant Gogo (bark) Entada phaseoloides as control. The positive result shows a honeycomb froth that is higher ... They would pulverize the roots, mixing in water to create a foam, and then add the suds to a stream. This would kill or ... Since prehistoric times, cultures throughout the world have used piscicidal (fish-killing) plants, mostly those containing ... to stimulate both the Th1 immune response and the production of cytotoxic T-lymphocytes (CTLs) against exogenous antigens. This ...

*Comparative genomic hybridization

8-12µl of each of labelled test and labelled reference DNA are mixed and 40 µg Cot-1 DNA® is added, then precipitated and ... Phytohaemagglutinin stimulated peripheral blood lymphocytes are used. 1mL of heparinised blood is added to 10ml of culture ... relative to ploidy level in the DNA of a test sample compared to a reference sample, without the need for culturing cells. The ... DNA from the sample to be tested is labeled with a red fluorophore (Cyanine 5) and a reference DNA sample is labeled with green ...

*Antibody

The B lymphocyte, in this ready-to-respond form, is known as a "naive B lymphocyte." The naive B lymphocyte expresses both ... Preclinical pharmacology and toxicity testing : Preclinical safety testing of antibody is designed to identify possible ... In the case of an Rh-incompatible mother and child, consequential blood mixing may sensitize an Rh- mother to the Rh antigen on ... The fused cells are called hybridomas, and will continually grow and secrete antibody in culture. Single hybridoma cells are ...

*Index of genetics articles

S-9 mix Sanger sequence Sanger sequencing Sarcoma Satellite Satellite chromosome Satellite DNA Scaffold Scanning hypothesis ... Species Specific-locus test Spectral karyotype Sperm Spermatid Spermatocyte Spermatogenesis Spermatogonium Spermatozoon ... Linkage analysis Linkage equilibrium Linkage group Linkage map Linking number Locus Lod score Lod score method Lymphocyte ... Cri du chat cRNA Cross Cross-fertilization Crossbreed Crossover Crossover suppressor Crossovers Cryptic coloration Culture ...

*Probiotic

... it must be tested for toxin production. One possible scheme for testing toxin production has been recommended by the EU ... Active Cultures Seal to refrigerated yogurt products that contain 100 million cultures per gram or frozen yogurt products ... Currently, the success of such treatment has been mixed since the use of probiotics to restore healthy populations of ... as well as increasing the proportion of T lymphocytes and natural killer cells. Clinical trials have demonstrated that ...

*Freemartin

Bruere AN, Fielden ED, Hutchings H (March 1968). "XX-XY mosaicism in lymphocyte cultures from a pig with freemartin ... Genetic testing for the Y-chromosome can be performed within days of birth and can aid in the early identification of a sterile ... A freemartin is the normal outcome of mixed twins in all cattle species which have been studied. It does not normally occur in ... Freemartins behave and grow in a similar way to castrated male cattle (steers). If suspected, a test can be done to detect the ...

*Regulatory T cell

CD4+ helper T cells from skin-test positive adults killed CD8+ T cells but not CD4+ helper T cells when added to culture media ... In vitro experiments have given mixed results regarding the requirement of cell-to-cell contact with the cell being suppressed ... Read, S; Malmström, V; Powrie, F (17 July 2000). "Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the ... This causes large numbers of tumor-infiltrating lymphocytes (TILs) to be found in the tumor microenvironment. Although it is ...

*QuantiFERON

This test was approved by the U.S. Food and Drug Administration (FDA) in 2005. Blood samples are mixed with antigens ( ... The test is based on the quantification of interferon-gamma (IFN-γ) released from sensitized lymphocytes in whole blood ... Clinical evaluation and additional tests (such as a chest radiograph, sputum smear, and culture) are needed to differentiate ... Assessment of the accuracy of these tests is limited by lack of a standard for confirming LTBI. As a diagnostic test, QFT: ...

*Human herpesvirus 6

A study of 259 patients with a "CFS-like" illness published shortly after HHV-6 was discovered used primary lymphocyte cultures ... A variety of tests are used in the detection HHV-6, some of which do not differentiate the two species. During 1986, Syed Zaki ... studies employing only serological techniques that do not distinguish active from latent infection have produced mixed results ... HHV-6A and HHV-6B infect almost all of the human populations that have been tested. HHV-6A has been described as more ...

*Cell culture

... other enzyme mixes are now available for this purpose. A small number of detached cells can then be used to seed a new culture ... In brief, lymphocytes isolated from the spleen (or possibly blood) of an immunised animal are combined with an immortal myeloma ... Cabrera CM, Cobo F, Nieto A, Cortés JL, Montes RM, Catalina P, Concha A (June 2006). "Identity tests: determination of cell ... Plant cell cultures are typically grown as cell suspension cultures in a liquid medium or as callus cultures on a solid medium ...

*Measles vaccine

It comes as a dried powder which is mixed with a specific liquid before being injected either just under the skin or into a ... The measles component of the MMR vaccine uses Attenuvax, which is grown in a chick embryo cell culture using the Enders' ... HIV-infected children may receive measles vaccines if their CD4+ lymphocyte count is greater than 15%. As a fellow at ... Verification that the vaccine was effective can be determined by blood tests. About 85% of children globally have received this ...

*Allergic contact dermatitis

The tests are again read at 72 or 96 hours after application. Patch testing is used for patients who have chronic, recurring ... In a similar fashion, cytotoxic T lymphocytes patrol an area of skin and play an important role in controlling both the ... Found by itself, or in Neosporin or Triple Antibiotic Fragrance mix - group of the eight most common fragrance allergens found ... be used to diagnose contact dermatitis and rule out other potential causes of the symptoms include a skin biopsy and culture of ...

*John Raymond Hobbs

Mixed lymphocyte reaction T-cell receptors. Phagocyte function. First to fully describe IgA deficiency. IgM deficiency ... Density and inducibility of T-cell receptors in relation to the age of the lymphocyte donor and the conditions of culture. ... Established the first non-invasive screening test of the newborn to detect those affected by cystic fibrosis 1968 As Chairman ... 6. 38-44 Yamamura, M., Nikbin, B., Hobbs, J.R. Standardisation of the mixed lymphocyte reaction (1976) Journal of Immunological ...

*Index of oncology articles

... cultured cell - cultured cell line - cumulative dose - curcumin - cutaneous breast cancer - cutaneous T-cell lymphoma - ... extrapleural pneumonectomy false-negative test result - false-positive test result - familial adenomatous polyposis - familial ... B lymphocyte - B3 antigen - B43-PAP immunotoxin - B7-1 - Bacillus Calmette Guérin - bacterial toxin - barium enema - barium ... mixed glioma - MLN2704 - modafinil - modality - modified radical mastectomy - Mohs surgery - molar pregnancy - molecular risk ...

*Helicteres isora

In-vitro cytoprotection activity of Foeniculum vulgare and Helicteres isora in cultured human blood lymphocytes and antitumour ... The fruit powder mixed along some other herbs and spices is given to new mothers as laddoo (Indian sweet dish) in order to cope ... Ayurvedic tests have described Murva as Helicteres isora and Sansevieria roxburghiana. B) Physical Identification There is a ...

*Severe combined immunodeficiency

A full blood lymphocyte count is often considered a reliable manner of diagnosing SCID, but higher lymphocyte counts in ... Due to the genetic nature of SCID, a higher prevalence is found in areas and cultures among which there is a higher rate of ... Transduction of the missing gene to hematopoietic stem cells using viral vectors is being tested in ADA SCID and X-linked SCID ... Severe combined immunodeficiency, SCID, also known as alymphocytosis, Glanzmann-Riniker syndrome, severe mixed immunodeficiency ...

*Arenavirus

Ribavirin displays mixed success in treating severe Arenaviral disease and is associated with significant toxicities. Effective ... The results of genetic sequencing tests conducted by epidemiologists at Columbia University in New York City, USA, and at the ... 2012). "Identification, characterization, and in vitro culture of highly divergent arenaviruses from boa constrictors and ... characteristically accompanied by large numbers of lymphocytes in the CSF (as the name LCM suggests). Lassa fever virus causes ...

*Effects of cannabis

... long-term users can produce positive tests for two to three months after ceasing cannabis use (see drug test). No fatal ... In the tonsils the CB2 receptors appear to be restricted to B-lymphocyte-enriched areas. THC and its endogenous equivalent ... system and neuronal cultures. Cannabidiol was significantly more protective than either vitamin E or vitamin C. The cannabinoid ... cannabis exhibits a mix of all properties, perhaps leaning the most towards hallucinogenic or psychedelic properties, though ...