Reif K, Cyster J (2002). "The CDM protein DOCK2 in lymphocyte migration". Trends Cell Biol. 12 (8): 368-73. doi:10.1016/S0962- ... Lu M, Ravichandran KS (2006). "Dock180-ELMO cooperation in Rac activation". Methods Enzymol. Methods in Enzymology. 406: 388- ...
Cooperation between helper T cells and cytotoxic T lymphocyte precursors. Annals of the New York Academy of Sciences, 532(1), ... Vaccination with cytotoxic T lymphocyte epitope‐containing peptide protects against a tumor induced by human papillomavirus ... and CD8+ cytotoxic T lymphocytes (CTLs) are able to induce tumor killing upon direct recognition of peptide antigens presented ...
CD8+ T lymphocytes destroy melanocytes in some parts of the skin what manifest like white spots on the skin. Multiple genes as ... Cooperation of TRM cells with other memory T cell populations provide tissue surveillance and clearance of the infections. ... Cytotoxic CD8+ T lymphocytes are able to recognize malignant cells. Production of neoantigens by tumour cells can lead to ... Skin TRM: TRM cells in the skin express cutaneous lymphocyte antigen (CLA) and CCR8 which are skin homing antigens. They have ...
"Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes". The Journal of Experimental Medicine. ... Cytotoxic T lymphocytes (CTLs) can recognize and destroy cancer cells. However, an inhibitory mechanism interrupts this ... T lymphocytes can recognize and destroy cancer cells. However, an inhibitory mechanism interrupts this destruction. Ipilimumab ... That signal binds to a receptor, cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), on the CTL and turns off the cytotoxic ...
Fakhri decided to investigate the cooperation between antibodies and lymphocytes to see if there might be parallels with the ... He called these lymphocytes "co-optable lymphocytes." As other scientists began to explore this phenomenon these lymphocytes ... He found that when lymphocytes were mixed with cancerous cells in the presence of antibodies the lymphocytes encircled the ... the cooperation between antibodies and lymphocytes and their role in immune response, the use of peritoneal macrophages in the ...
Zhang Q, Li Y, Howard TH (2002). "Hair-forming activity of human lymphocyte specific protein 1 requires cooperation between its ... Lymphocyte-specific protein 1 is a protein that in humans is encoded by the LSP1 gene. This gene encodes an intracellular F- ... "Entrez Gene: LSP1 lymphocyte-specific protein 1". Jongstra-Bilen J, Young AJ, Chong R, Jongstra J (1990). "Human and mouse LSP1 ... 1993). "Human lymphocyte-specific pp52 gene is a member of a highly conserved dispersed family". Genomics. 15 (3): 515-20. doi: ...
Sallusto, F.; Lenig, D.; Förster, R.; Lipp, M.; Lanzavecchia, A. (1999). "Two subsets of memory T lymphocytes with distinct ... This study uncovered a critical step in the process of T-B cell cooperation that is essential for high affinity antibody ... Viola, A.; Schroeder, S.; Sakakibara, S.; Lanzavecchia, A. (1999). "T lymphocyte costimulation mediated by reorganization of ... lymphocyte activation and immunological memory and iii) human monoclonal antibodies. In 1985, using antigen-specific T and B ...
In patients with active sarcoidosis, which is characterized by lymphocyte-macrophage cooperation, lymphocyte peripolesis ... The lymphocytes could be seen moving around a macrophage while maintaining contact. Sharp, J. A.; Burwell, R. G. (1960-11-05 ... Lyons DJ, Gautam A, Clark J, Harries MG, Mitchell EB, Milledge JS, Balfour BM (Jan 1992). "Lymphocyte macrophage interactions: ... It was observed between lymphocytes and macrophages following skin grafts between subjects, and after immune challenge with ...
Bhattacharya S, Eckner R, Grossman S, Oldread E, Arany Z, D'Andrea A, Livingston DM (September 1996). "Cooperation of Stat2 and ... "Differential regulation of constitutive major histocompatibility complex class I expression in T and B lymphocytes". The ... Bhattacharya S, Eckner R, Grossman S, Oldread E, Arany Z, D'Andrea A, Livingston DM (September 1996). "Cooperation of Stat2 and ...
T and B cell cooperation in immune response 1965 - Discovery of lymphocyte mitogenic activity, "blastogenic factor" (Shinpei ... Discovery of lymphocyte circulation (James Gowans) 1960 - Discovery of lymphocyte "blastogenic transformation" and ... The lymphocyte cytolysis Cr51 release assay (Theodore Brunner) and (Jean-Charles Cerottini) 1971 - Peter Perlmann and Eva ... Demonstration that glucocorticoids inhibit PHA-induced lymphocyte proliferation (Peter Nowell) 1963 - Development of the plaque ...
Target cell death without added complement after cooperation of 7S-antibodies with non-immune lymphocytes. (1972) Nature New ... Mixed lymphocyte reaction T-cell receptors. Phagocyte function. First to fully describe IgA deficiency. IgM deficiency ... 6. 38-44 Yamamura, M., Nikbin, B., Hobbs, J.R. Standardisation of the mixed lymphocyte reaction (1976) Journal of Immunological ... 219-317 Foroozanfar, N., Yamamura, M. and Hobbs, J.R. Standardization of lymphocyte transformation to candida immunogen, (1974 ...
In 2000, Hoerr published his doctoral thesis entitled "RNA vaccine for the induction of specific cytotoxic T-lymphocytes (CTL) ... in cooperation with Hans-Georg Rammensee, Institute of Immunology and Cell Biology (both: University of Tübingen) on the topic ... "In vivo application of RNA leads to induction of specific cytotoxic T lymphocytes and antibodies". European Journal of ... of RNA vaccines for the induction of specific cytotoxic T lymphocytes (CTL) and antibodies. ...
Lymphocytes including CD4+, CD8+, gamma-delta T (γδ-T), invariant NKT and innate lymphoid cells (ILCs) are primary sources of ... "Cooperation of interleukin-17 and interferon-gamma on chemokine secretion in human fetal intestinal epithelial cells". Clinical ... Shin HC, Benbernou N, Esnault S, Guenounou M (April 1999). "Expression of IL-17 in human memory CD45RO+ T lymphocytes and its ... "Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation". Nature Medicine. 13 (10 ...
McDonald C, Reich NC (July 1999). "Cooperation of the transcriptional coactivators CBP and p300 with Stat6". J. Interferon ... "Regulation of E2A activities by histone acetyltransferases in B lymphocyte development". J. Biol. Chem. 278 (4): 2370-6. doi: ... modulates co-operation between myocyte enhancer factor 2A (MEF2A) and thyroid hormone receptor-retinoid X receptor". Biochem. J ...
It was first identified in cytotoxic lymphocyte (CTL) target cells. TIA1 acts in the nucleus to regulate splicing and ... As part of the translational stress response, TIA1 works in cooperation with other RNA binding proteins to sequester RNA ... Stress granule T-cell large granular lymphocyte leukemia GRCm38: Ensembl release 89: ENSMUSG00000071337 - Ensembl, May 2017 " ... monoclonal antibody reactive with a 15-kDa cytoplasmic granule-associated protein defines a subpopulation of CD8+ T lymphocytes ...
Retrieved 2012-06-23.; "Monoclonal antibodies that bind to soluble IGE but do not bind IGE on IGE expressing B lymphocytes or ... "Tripartite Cooperation Agreement". Archived from the original on 2016-08-22. Retrieved 2017-09-07. "Genentech: Press Releases ... Retrieved 2012-06-23.. Tripartite Cooperation Agreement, by and between NOVARTIS PHARMA AG, GENENTECH, INC, AND TANOX, INC. " ... on the surface of mIgE-expressing B lymphocytes. Unlike an ordinary anti-IgE antibody, it does not bind to IgE that is already ...
He is also known for his early work on oncogenes carried by retroviruses and oncogene cooperation in leukemia formation. In the ... Later (2004) he managed to convert B lymphocytes into functional macrophages, using C/EBPa as a driver. Using the same approach ... Finally, he found that forced C/EBPa expression in malignant lymphocyte precursors leads to the formation of macrophages and ...
Additionally, mice deficient in pre-mir-155 showed clear defects in lymphocyte development and generation of B- and T-cell ... in this fashion of selective pressure those B Cells that demonstrated high-affinity receptors and cooperation with T cells ( ... 2007), maturation and specificity of miR-155-deficient B-lymphocytes are impaired since the process relies on AID enzyme which ... MiR-155 is crucial for proper lymphocyte development and maturation. Details of various manifestations of miR-155 levels and ...
This allowed him to conclude that chromatin remodeling affects lymphocyte differentiation. One of the biggest discoveries that ... The CBX family of proteins in transcriptional repression and memory Cooperation between complexes that regulate chromatin ... "Ikaros DNA-Binding Proteins Direct Formation of Chromatin Remodeling Complexes in Lymphocytes". Immunity. 10 (3): 345-355. doi: ...
CXCL13/BLC in B lymphocytes and CCL19/ELC in thymocytes (immature lymphocytes) emigrating from the thymus as well as CCL21/SLC ... Lu M, Ravichandran KS (2006). Dock180-ELMO cooperation in Rac activation. Methods in Enzymology. Vol. 406. pp. 388-402. doi: ... Reif K, Cyster J (2003). "The CDM protein DOCK2 in lymphocyte migration". Trends in Cell Biology. 12 (8): 368-73. doi:10.1016/ ... The HIV-1 protein Nef is able to constitutively activate Dock2 in T lymphocytes which disrupts chemotaxis and immunological ...
He wrote his thesis on "mixed cultures of lymphocytes: search for a specific inhibition of the immunological response to the ... he signed a cooperation agreement with the Laotian Minister of Health, Pomnek Dalaloy, and the French Ambassador to Laos. He ... Cultures mixtes de lymphocytes : recherche d'une inhibition spécifique de la réponse immunologique aux spécificités ...
In 2007, Cohen earned the International Scientific and Technological Cooperation Award of Shanghai Municipality. In 2008, the ... University of the Health Sciences in 1993 having completed a thesis entitled The Effects of Cocaine and Stress on Lymphocyte ... "International Scientific and Technological Cooperation Award". Archived from the original on 2015-04-14. "Shanghai Silver ...
Lu M, Ravichandran KS (2006). "Dock180-ELMO cooperation in Rac activation". Meth. Enzymol. Methods in Enzymology. 406: 388-402 ... This disorder is considered a combined immunodeficiency because it includes both decreased lymphocyte numbers and defective ... lymphocyte function. It can also be classified as a type of autosomal recessive hyperimmunoglobulinemia E syndrome. Laboratory ...
In vivo application of RNA leads to the induction of specific cytotoxic T lymphocytes and antibodies. In: Eur.J.Immunol, 30, ... has been determined for the first time by Günther Jung's PhD student Stefan Stevanovic in cooperation with the cell-biological ... "In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine". Nature. Springer Science and ... PhD thesis Ingmar Hoerr was the first to develop an RNA vaccine for the induction of specific cytotoxic T-lymphocytes (CTL) and ...
For example, Klf4 transactivates the iNOS promoter in cooperation with p65 (RelA), and the p21Cip1/Waf1 promoter in cooperation ... and in B lymphocytes. Recently, KLF3 was shown to be important in heart development. KLF4 (originally Gut KLF) is an important ... acts as a transcriptional activator or repressor depending on the promoter context and/or cooperation with other transcription ...
... karyotype knockout leukemia List of human genetic disorders locus LOD score lymphocyte malformation Gene mapping marker ... On the Origin of Species Charles Darwin The eclipse of Darwinism Common descent Evidence of common descent Speciation Co-operation ...
Transmission relies primarily on the transfer of infected lymphocytes from one animal to the next, and BLV positive animals ... Willems, L.; Heremans, H.; Chen, G.; Portetelle, D.; Billiau, A.; Burny, A.; Kettmann, R. (May 1990). "Cooperation between ... lymphocytes as a DNA intermediate (the provirus), or exist as unintegrated circular or linear forms. Besides structural and ... "Ablation of non-coding RNAs affects bovine leukemia virus B lymphocyte proliferation and abrogates oncogenesis". PLOS Pathogens ...
The patient's cooperation and age of the patient are very important as well. Patients may experience pain or discomfort during ... The lesion is predominantly composed of plasma cells that are mixed with macrophages and lymphocytes with endothelial cells and ...
TLRs often activate MZ B cells after recognizing microbial molecular structures in cooperation with the BCR. These innate-like ... Cerutti A, Cols M, Puga I (February 2013). "Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes". ... Lopes-Carvalho T, Foote J, Kearney JF (2005). "Marginal zone B cells in lymphocyte activation and regulation". Curr Opin ... Hardy, Richard (2008). "Chapter 7: B Lymphocyte Development and Biology". In Paul, William (ed.). Fundamental Immunology (Book ...
Lin and Hamann's group show all human cytotoxic lymphocytes, including CD56dull NK cells and CD27-CD45RA+ effector-type CD8+ T ... indicating cooperation of GPR56 and α3β1 integrin in modulation of the development of the cerebral cortex. More recently, the ... October 2011). "Specific expression of GPR56 by human cytotoxic lymphocytes". Journal of Leukocyte Biology. 90 (4): 735-40. doi ...