... (Scn), lipocalin-2, NGAL, 24p3 is a mammalian lipocalin-type protein that can prevent iron acquisition by ... The lipocalin family of binding proteins typically have a conserved eight-stranded β-barrel fold with a calyx binding site, ... Since lipocalin-2 cannot bind the long fatty acid chain carboxymycobactins of mycobacteria, it is apparent that a number of ... The lipocalin family of binding proteins are produced by the immune system and sequester ferric siderophore complexes from the ...
The lipocalins that have been identified as biliproteins have been found in a wide variety of insects, but mainly in the order ... In insects, biliprotein lipocalins generally function to facilitate the changing of colours during camouflage, but other roles ... Ganfornina, M. D.; Kayser, H.; Sanchez, D. (2006). "6. Lipocalins in Arthropoda: Diversification and Functional Explorations". ... and so their lipocalin nature is still open. In a 1988 study conducted by Hugo Scheer and Harmut Kayser, biliproteins were ...
The human gene encoding it was cloned in 1986 and the deduced protein sequence revealed that ApoD is a member of the lipocalin ... Sánchez D, Ganfornina MD, Martínez S (January 2002). "Expression pattern of the lipocalin apolipoprotein D during mouse ... Breustedt DA, Schönfeld DL, Skerra A (February 2006). "Comparative ligand-binding analysis of ten human lipocalins". Biochimica ... also known as lipocalins. It is a glycoprotein of estimated molecular weight 33 KDa. Apo-D is closely associated with the ...
This gene and a highly similar family member are located in a cluster of lipocalin genes on chromosome 9. Alternatively spliced ... This gene encodes a small extracellular protein belonging to the lipocalin superfamily. The protein is thought to transport ... Breustedt DA, Schönfeld DL, Skerra A (2006). "Comparative ligand-binding analysis of ten human lipocalins". Biochim. Biophys. ...
Bugos RC, Hieber AD, Yamamoto HY (June 1998). "Xanthophyll cycle enzymes are members of the lipocalin family, the first ... Hieber AD, Bugos RC, Yamamoto HY (October 2000). "Plant lipocalins: violaxanthin de-epoxidase and zeaxanthin epoxidase". ...
This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have ... Seppälä M, Taylor RN, Koistinen H, Koistinen R, Milgrom E (Aug 2002). "Glycodelin: a major lipocalin protein of the ... Salier JP (Oct 2000). "Chromosomal location, exon/intron organization and evolution of lipocalin genes". Biochimica et ... Halttunen M, Kämäräinen M, Koistinen H (Oct 2000). "Glycodelin: a reproduction-related lipocalin". Biochimica et Biophysica ...
Hurst J, Beynon RJ, Roberts SC, Wyatt TD (October 2007). Urinary Lipocalins in Rodenta:is there a Generic Model?. Chemical ...
They belong to a larger family of proteins known as lipocalins. Mups are encoded by a cluster of genes, located adjacent to ... Smith W, Butler AJ, Hazell LA, Chapman MD, Pomés A, Nickels DG, Thomas WR (November 2004). "Fel d 4, a cat lipocalin allergen ... The Mup found in pigs, named salivary lipocalin (SAL), is expressed in the salivary gland of males where it tightly binds ... Mups are members of a large family of low-molecular weight (~19 kDa) proteins known as lipocalins. They have a characteristic ...
doi:10.1007/978-1-4419-8602-3_7. ISBN 978-1-4419-8602-3. Sawyer L, Kontopidis G (October 2000). "The core lipocalin, bovine ... January 2018). "Retinoic acid prevents immunogenicity of milk lipocalin Bos d 5 through binding to its immunodominant T-cell ... β-lactoglobulin is a lipocalin protein, and can bind many hydrophobic molecules, suggesting a role in their transport. β- ...
Fel d 4 and Fel d 7 are cat lipocalins. Fel d 4 and Fel d 7 are one of the most common cat allergens after Fel d 1. Fel d 4 is ... a cat lipocalin allergen". Clinical & Experimental Allergy. 34 (11): 1732-1738. doi:10.1111/j.1365-2222.2004.02090.x. ISSN 0954 ...
It belongs to a protein family, the lipocalins, all members of which are shaped as a basket built from eight beta-strands of ... Åkerström, B.; Lögdberg, L.; Berggård, T.; Osmark, P.; Lindqvist, A. (2000). "Alpha-1-microglobulin: a yellow-brown lipocalin ...
LMBR1 is a known lipocalin transmembrane receptor. TMEM259 is another transmembrane protein. There are several promoters of the ...
Plant lipocalins: violaxanthin de-epoxidase and zeaxanthin epoxidase. „Biochim Biophys Acta". 1482 (1-2), s. 84-91, Oct 2000. ...
"An iron delivery pathway mediated by a lipocalin". Molecular Cell. 10 (5): 1045-56. doi:10.1016/s1097-2765(02)00710-4. PMID ...
... or canis familiaris allergen 1 is a lipocalin allergen produced by dogs in their tongue epithelial tissue. It is ... are salivary lipocalin proteins: cloning and immunological characterization of the recombinant forms". Immunology. 92 (4): 577- ... "Structural similarities of human and mammalian lipocalins, and their function in innate immunity and allergy". Allergy. 71 (3 ... homologous with the human lipocalin LCN1. Major allergen Can f 1 UniProtKB. Grammer, Leslie C. and Paul A. Greenberger (2009), ...
This resembles the lipocalin fold, although no sequence homology exists with lipocalins. In TTHA0802, the protein binds the ... In both cases, the protein is a homodimer, each monomer being characterized by a lipocalin fold. Stancik LM, Stancik DM, ...
Instead, they are derived from human lipocalins which are a family of naturally binding proteins. Anticalin proteins are being ... The main structure of Anticalin proteins is identical to wild type lipocalins. Conformational deviations are primarily located ... harnessing the structural plasticity of the lipocalin ligand pocket to engineer novel binding activities". FEBS J. 275 (11): ...
Members of the lipocalin family are known to bind a variety of small hydrophobic ligands, including biliverdin, in a similar ... The Rhodnius prolixus nitrophorin structures reveal lipocalin-like eight-stranded β-barrel, three α-helices and two disulfide ... Montfort, W.R., Weichsel, A. and Andersen, J.F. (2000). "Nitrophorins and related antihemostatic lipocalins from Rhodnius ...
The lipocalin family is a large and diverse family of proteins with functions as small hydrophobic molecule transporters. Beta- ... Lipocalins are known to have very low sequence similarity with high structural similarity.[citation needed] The only conserved ... These hydrogen bonds lie at the bottom of the cavity, which suggests that the closure of the entrance of a lipocalin starts ... The overall shape of beta-lactoglobulin is characteristic of the lipocalin family.[citation needed] In the absence of alpha- ...
In vertebrates, OBPs are a part of the lipocalin family. They are structurally characterized by a β-barrel motif composed of ...
... carbachol loses its capacity to promote the secretion of lipocalin. However, lacritin stimulates lipocalin secretion even in ... Also down regulated are tear lipocalin-1 and cystatin S. Fungal keratitis accounts for half of all corneal ulcers in Africa and ... Lacritin stimulated secretion of tear proteins lipocalin and lactoferrin from monkey lacrimal acinar cells does not appear to ... including that of lipocalin-1 and lactoferrin), cell survival and regeneration of the corneal epithelium after wounding. This ...
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A) in the blood. It delivers ... Newcomer ME, Ong DE (October 2000). "Plasma retinol binding protein: structure and function of the prototypic lipocalin". ...
... lipocalin-like protein". J. Biol. Chem. 278 (44): 43728-35. doi:10.1074/jbc.M304484200. PMID 12909634. Graham, AI; Hunt, S; ...
Other innate immune mediators include beta-defensin 2, and lipocalin-2; pro-inflammatory cytokines, interleukins IL6, and IL8; ...
Gaudineau B, Fougère M, Guaddachi F, Lemoine F, de la Grange P, Jauliac S (1 October 2012). "Lipocalin 2 (LCN2), the TNF-like ... NFAT1 regulates the expression of the TWEAKR and its ligand TWEAK with the Lipocalin 2 to increase breast cancer cell invasion[ ... "NFAT3 transcription factor inhibits breast cancer cell motility by targeting the Lipocalin 2 gene". Oncogene. 29 (15): 2292-301 ... 200] and NFAT3 inhibits Lipocalin 2 expression to blunt the cell invasion.[199] ...
This protein belongs to the lipocalin family and interacts with C8α. The binding site on C8α is known, however, the precise ...
Natural protease inhibitors include the family of lipocalin proteins, which play a role in cell regulation and differentiation ... Lipophilic ligands, attached to lipocalin proteins, have been found to possess tumor protease inhibiting properties. The ...
The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with ... Duan J, Dahlback B, Villoutreix BO (Jun 2001). "Proposed lipocalin fold for apolipoprotein M based on bioinformatics and site- ... Ahnström J, Faber K, Axler O, Dahlbäck B (2007). "Hydrophobic ligand binding properties of the human lipocalin apolipoprotein M ...
Eguchi Y, Eguchi N, Oda H, Seiki K, Kijima Y, Matsu-ura Y, Urade Y, Hayaishi O (Dec 1997). "Expression of lipocalin-type ... "Lipocalin-type prostaglandin D synthase in human male reproductive organs and seminal plasma". Biology of Reproduction. 58 (2 ...
One study suggests the drug amplifies production of neutrophil gelatinase-associated lipocalin (NGAL) in the skin, which has ... "Neutrophil gelatinase-associated lipocalin mediates 13-cis retinoic acid-induced apoptosis of human sebaceous gland cells" ...