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*  Cysteinyl leukotriene receptor 1
"Effects of cysteinyl leukotrienes in small human bronchus and antagonist activity of montelukast and its metabolites". Clinical ... Cysteinyl leukotriene receptor 1, also termed CYSLTR1, is a receptor for cysteinyl leukotrienes (LT) (see leukotrienes# ... "Up-regulation of cysteinyl leukotriene 1 receptor by IL-13 enables human lung fibroblasts to respond to leukotriene C4 and ... "Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand ...
*  Leukotriene D4
Pharmacological agents that inhibit the function of these leukotrienes are leukotriene receptor antagonists (e.g. Zafirlukast, ... Leukotriene D4 (LTD4) is one of the leukotrienes. Its main function in the body is to induce the contraction of smooth muscle, ... Other leukotrienes that function in a similar manner are leukotrienes C4 and E4. ...
*  Antileukotriene
Leukotriene receptor antagonists are sometimes colloquially referred to as leukasts. Leukotriene receptor antagonists, such as ... or leukotriene receptor antagonist (cysteinyl leukotriene receptors) and consequently opposes the function of these ... Leukotriene antagonists at the US National Library of Medicine Medical Subject Headings (MeSH). ... Sulfido-peptide leukotrienes (LTC4, LTD4, LTE4, also known as the slow-releasing substances of anaphylaxis) and LTB4, a ...
*  Leukotriene receptor antagonist-associated Churg-Strauss syndrome
... may occur in asthma patients being treated with leukotriene ... Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome) Leukotriene antagonist Skin lesion James, William; ... receptor antagonists, occurring 2 days to 10 months after the antagonist has been started, with features of the syndrome ...
*  L 663536
... is a leukotriene antagonist. It may perform this by blocking the 5-lipoxygenase activating protein (FLAP), thus ...
*  Mastocytosis
Leukotriene antagonists block receptors targeted by leukotrienes released from mast cells. Mast cell stabilizers help prevent ...
*  Eicosanoid
"The employment of leukotriene antagonists in cutaneous diseases belonging to allergological field". Mediators of Inflammation. ... LTA4 is then metabolized either to LTB4 by Leukotriene A4 hydrolase or Leukotriene C4 (LTC4) by either LTC4 synthase or ... "Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand ... Bäck M, Powell WS, Dahlén SE, Drazen JM, Evans JF, Serhan CN, Shimizu T, Yokomizo T, Rovati GE (2014). "Update on leukotriene, ...
*  Ketotifen
Besides its anti-histaminic activity, it is also a functional leukotriene antagonist and a phosphodiesterase inhibitor. "[O]ral ...
*  Gerd Rasp
Rasp G. Is there a role for leukotriene antagonists in the prevention of recurrent nasal polyps? In: Current Opinion in Allergy ...
*  Leukotriene
... antagonists are used to treat these disorders by inhibiting the production or activity of leukotrienes. The name ... Several leukotriene receptor antagonists such as montelukast and zafirlukast are used to treat asthma. Recent research points ... Leukotrienes also have a powerful effect in bronchoconstriction and increase vascular permeability. Leukotrienes contribute to ... In excess, the cysteinyl leukotrienes can induce anaphylactic shock. A chemical synthesis of Leukotriene A methyl ester Eoxins ...
*  Ablukast
... (INN) is a leukotriene antagonist which has applications in the treatment of inflammatory skin conditions. Rosenbach, ... T; Csatò, M; Czarnetzki, BM (1988). "Studies on the role of leukotrienes in murine allergic and irritant contact dermatitis". ...
*  Mast cell
Leukotriene antagonists (such as montelukast and zafirlukast) block the action of leukotriene mediators and are being used ... leukotrienes, and varieties of chemokines and cytokines some of which are known to disrupt the integrity of the blood-brain ... leukotrienes, and eoxins). Research into an immunological contribution to autism suggests that autism spectrum disorder (ASD) ... thromboxane prostaglandin D2 leukotriene C4 platelet-activating factor cytokines TNF-α basic fibroblast growth factor ...
*  Exercise-induced bronchoconstriction
Some physicians prescribe inhaled anti-inflammatory mists such as corticosteroids or leukotriene antagonists, and mast cell ...
*  Fenbufen
Nonsteroidal Antiinflammatory Drugs and Leukotriene Receptor Antagonists. Chapter 22 in Drug-Induced Liver Disease, 3rd Edition ...
*  Pulmonology
... leukotriene antagonists). A common example being the usage of inhalers in the treatment of inflammatory lung conditions such as ...
*  Hives
Pacor ML, Di Lorenzo G, Corrocher R (2001). "Efficacy of leukotriene receptor antagonist in chronic urticaria. A double-blind, ... AU Erbagci Z SO (2002). "The leukotriene receptor antagonist montelukast in the treatment of chronic idiopathic urticaria: a ... Leukotrienes are released from mast cells along with histamine. The medications, montelukast and zafirlukast block leukotriene ... then to adding a leukotriene antagonist, then to using an older antihistamine, then to using systemic steroids and finally to ...
*  Perovskia atriplicifolia
... taxiresinol and five other compounds to act as leukotriene antagonists. The isorinic acid derivative perovskoate may also ...
*  Aspirin-induced asthma
... and leukotriene antagonists. Leukotriene antagonists and inhibitors (montelukast, zafirlukast, and zileuton) are often helpful ... Overexpression of both the cysteinyl leukotriene receptor 1 and the leukotriene C4 synthase enzyme has been shown in ... which likely relates to the increased response to leukotrienes and increased production of leukotrienes seen in the disorder. ... Urinary cystyl-leukotriene or urinary LTE4 can be used after a supervised challenge with aspirin. In aspirin sensitivity, no ...
*  Salicylate sensitivity
September 2007). "CysLTR1 promoter polymorphism and requirement for leukotriene receptor antagonist in aspirin-intolerant ...
*  Photoleukomelanodermatitis of Kobori
Leukotriene receptor antagonist-associated Churg-Strauss syndrome List of cutaneous conditions Rapini, Ronald P.; Bolognia, ...
*  Zafirlukast
Like other leukotriene receptor antagonists, zafirlukast is thought to be useful for the long-term treatment of asthma, but it ... These cysteinyl leukotrienes include leukotriene C4, leukotriene D4, and leukotriene E4, all of which are produced by ... Zafirlukast is an antagonist of cysteinyl leukotriene receptor 1 (CysLT1), a receptor found throughout the smooth muscle of the ... As a general rule, leukotriene receptor antagonists like zafirlukast are more effective in children that are younger and whose ...
*  Pharmaceutical drug
Leukotriene antagonists androgens, antiandrogens, estrogens, gonadotropin, corticosteroids, human growth hormone, insulin, ... dopamine antagonists, antihistamines, cholinergics, anticholinergics, emetics, cannabinoids, and 5-HT (serotonin) antagonists. ... H2-receptor antagonists, cytoprotectants, prostaglandin analogues Lower digestive tract: laxatives, antispasmodics, ...
*  Asthma
"Leukotriene receptor antagonists in addition to usual care for acute asthma in adults and children". Cochrane Database of ... Leukotriene receptor antagonists (such as montelukast and zafirlukast) may be used in addition to inhaled corticosteroids, ... Miligkos, M; Bannuru, RR; Alkofide, H; Kher, SR; Schmid, CH; Balk, EM (17 November 2015). "Leukotriene-receptor antagonists ... an leukotriene antagonist or a mast cell stabilizer by mouth is recommended. For those who have daily attacks, a higher dose of ...
*  Fluproquazone
Nonsteroidal Antiinflammatory Drugs and Leukotriene Receptor Antagonists, Ch 22 in Drug-induced Liver Disease (Third Edition). ...
*  Exhaled nitric oxide
Furthermore, drugs used to treat asthma (such as inhaled glucocorticoids or leukotriene receptor antagonists) also reduce eNO ...
*  Bronchoconstriction
Muscarinic antagonists (anti-cholinergics): Blocking the muscarinic acetylcholine receptors in pulmonary smooth muscle tissue ... During an episode of this type of bronchoconstriction, the levels of inflammatory mediators, particularly leukotrienes, ... These medications include short-acting muscarinic antagonists (SAMAs) such as ipratropium, and long-acting muscarinic ... antagonists (LAMA) such as tiotropium. Onset of action for SAMAs is typically between 30-60 minutes, making these drugs less ...
*  LTRA
... may refer to: Land Tenure Reform Association LeukoTriene Receptor Antagonist Long term response action LtrA, open reading ...