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*  Hairy cell leukemia
They may be related to pre-plasma marginal zone B cells or memory cells. Cytokine production is disturbed in HCL. Hairy cells ... In 2013 the Hairy Cell Leukemia Foundation was created when the Hairy Cell Leukemia Consortium and the Hairy Cell Leukemia ... "Integrated human T-cell leukemia virus II genome in CD8 + T cells from a patient with "atypical" hairy cell leukemia: evidence ... Hairy cell leukemia-variant, or HCL-V, is usually described as a prolymphocytic variant of hairy cell leukemia. It was first ...
*  Plasma cell leukemia
Secondary plasma cell leukemia (sPCL) results from the comparatively slow development of plasma cell/plasma cell precursor ... Plasma cell leukemia (PCL) is a plasma cell dyscrasia, i.e. a disease involving the malignant degeneration of a subtype of ... PCL may present as primary plasma cell leukemia, i.e. in patients without prior history of a plasma cell dyscrasia or as ... circulating plasma cells had a prognosis much worse than that for multiple myeloma and similar to that for plasma cell leukemia ...
*  Plasma cell dyscrasia
In the most malignant form of plasma cell dyscrasias, primary plasma cell leukemia, the plasma cell population contains >1900 ... There are two forms of plasma cell leukemia: Primary plasma cell leukemia in which patients without a history of multiple ... Plasma cell dyscrasias (also termed plasma cell disorders and plasma cell proliferative diseases) are a spectrum of ... Plasma cell leukemia is a form of multiple myeloma in which significant numbers of typically immature appearing plasma cells, i ...
*  Waldenström's macroglobulinemia
"Chronic Lymphoid Leukemias and Plasma Cell Disorders". In Dale DD, Federman DD. ACP Medicine. New York, NY: WebMD Professional ... lymphoplasmacytoid cells and plasma cells. Both cell types are white blood cells. WM is characterized by having high levels of ... WM is commonly classified as a form of plasma cell dyscrasia. Similar to other plasma cell dyscrasias that, for example, lead ... One recent investigation showed that a population of cells, lacking both B-cell and plasma cell markers, has characteristics of ...
*  2016 in Taiwan
21 May - Ku Chin-shui, 56, Taiwanese aboriginal athlete, plasma cell leukemia. 27 May - Wang You-theng, 89, Taiwanese ...
*  List of hematologic conditions
... cyclophosphamide and dexamethasone may be effective for plasma cell leukemia". Jpn. J. Clin. Oncol. 37 (5): 382-4. doi:10.1093/ ... "Complete remission of primary plasma cell leukemia with bortezomib, doxorubicin, and dexamethasone: a case report". Cases J. 2 ... Leukemia is a malignancy producing of white blood cells in bone marrow. It can be a serious disease if not treated early. ... These cancers include leukemias, lymphomas, and myelomas. These particular types of cancers can arise as defected mature cell ...
*  Smouldering myeloma
Thus, some patients with smouldering myeloma progress to multiple myeloma and plasma cell leukemia. Smouldering myeloma, ... 500 mg per 24 h AND/OR Clonal plasma cells >10% and 60% plasma cells in bone marrow OR Involved/Uninvolved light chain ratio> ... stage of multiple myeloma and can subsequently lead to the extremely malignant stage of secondary plasma cell leukemia. ... In this spectrum of diseases, a clone of plasma cells secreting monoclonal paraprotein (also termed myeloma protein or M ...
*  Multiple myeloma
... plasma cell leukemia. Thus, a fundamental genetic instability in plasma cells or their precursors leads to the following ... Multiple myeloma, also known as plasma cell myeloma, is a cancer of plasma cells, a type of white blood cell normally ... The plasma cells seen in multiple myeloma have several possible morphologies. Typical of plasma cells, they will usually have ... Plasma cell dyscrasia, the spectrum of plasma cell disorders which evolve from benign to malignant conditions Development of ...
*  CA-125
... in primary plasma cell leukemia: a case report and review of the literature". Clinical Lymphoma & Myeloma. 8 (5): 312-4. doi: ... MUC16 is also thought to participate in cell-to-cell interactions that enable the metastasis of tumor cells. This is supported ... Evidence suggests that expression of the cytoplasmic tail of MUC16 enables tumor cells to grow, promotes cell motility and may ... thereby protecting cancer cells from the immune response. Further evidence that MUC16 can protect tumor cells from the immune ...
*  Serum protein electrophoresis
... plasma cell leukemia and solitary plasmacytomas also produce an M-spike. Oligoclonal gammopathy is indicated by one or more ... Fibrinogen from plasma samples will be seen in the beta gamma region. Fibrinogen, a beta-2 protein, is found in normal plasma ... Cold insoluble globulin forms a band here which is not seen in plasma because it is precipitated by heparin. There are low ... Lysozyme may be seen as a band cathodal to gamma in myelomonocytic leukaemia in which it is released from tumour cells. Jenkins ...
*  Ku Chin-shui
Ku was diagnosed with cancer in 2014, and died of plasma cell leukemia on 25 May 2016 at National Taiwan University Hospital in ...
*  Macroglobulinemia
It is a plasma cell dyscrasia, resembling leukemia, with cells of lymphocytic, plasmacytic, or intermediate morphology, which ... There is diffuse infiltration by the malignant cells of the bone marrow and also, in many cases, of the spleen, liver, or lymph ...
*  PCL
... a radar system exploiting commercial broadcast signals Phosphorus pentachloride or Phosphorus trichloride Plasma cell leukemia ...
*  Plasma cell gingivitis
Histologically plasma cell gingivitis shows mainly plasma cells. The differential diagnosis is with acute leukemia and multiple ... Plasma cell gingivits is rare, and plasma cell cheilitis is very rare. Most people with plasma cell cheilitis have been elderly ... plasma cell cheilitis, where the lips are involved, and other terms such as plasma cell orifacial mucositis, or plasma cell ... Plasma cell gingivits and plasma cell cheilitis are thought to be hypersensitivity reactions to some antigen. Possible sources ...
*  Clinical Lymphoma, Myeloma & Leukemia
... and plasma-cell dyscrasias. The journal is abstracted and indexed in Index Medicus/MEDLINE/Pubmed, EMBASE, Excerpta Medica, ... Clinical Lymphoma, Myeloma & Leukemia is a peer-reviewed medical journal published by Elsevier (previously by CIG Media Group ... "Clinical Lymphoma, Myeloma & Leukemia". 2014 Journal Citation Reports. Web of Science (Science ed.). Thomson Reuters. 2015. ... The journal covers research on detection, diagnosis, prevention, and treatment of lymphoma, myeloma, leukemia, and related ...
*  Plasma cell
Waldenström macroglobulinemia and plasma cell leukemia are malignant neoplasms ("cancer") of the plasma cells. Multiple myeloma ... Plasma cells, also called plasma B cells, plasmocytes, plasmacytes, or effector B cells, are white blood cells that secrete ... In humans, CD27 is a good marker for plasma cells, naive B cells are CD27-, memory B-cells are CD27+ and plasma cells are ... Germinal center B cells may differentiate into memory B cells or plasma cells. Most of these B cells will become plasmablasts ( ...
*  Cryoglobulinemia
... see plasma cell dyscrasia, Waldenström's macroglobulinemia, and chronic lymphocytic leukemia). This involves appropriate ... B-cell chronic lymphocytic leukemia, and Castleman's disease; they occur rarely in non-B cell hematological disorders such as ... The cryoglobulins in plasma or serum precipitate at lower temperatures (e.g. 4°C). Since cryofibrinogens are present in plasma ... promotes cell death by apoptosis in cells accumulating immunoglobulins) in patients with monoclonal immunoglobulin-induced ...
*  ICD-10 Chapter II: Neoplasms
Plasma cell leukemia (C90.2) Plasmacytoma, extramedullary (C91) Lymphoid leukemia (C91.0) Acute lymphoblastic leukemia (C91.1) ... Leukemia of unspecified cell type (C95.0) Acute leukemia of unspecified cell type (C95.1) Chronic leukemia of unspecified cell ... Chronic lymphocytic leukemia (C91.4) Hairy cell leukemia (C92) Myeloid leukemia (C92.0) Acute myeloid leukemia (C92.1) Chronic ... Subacute leukemia of unspecified cell type (C95.7) Other leukemia of unspecified cell type (C95.9) Leukemia, unspecified (C96) ...
*  Tumors of the hematopoietic and lymphoid tissues
... macrophages and mast cells; the lymphoid cell line produces B, T, NK and plasma cells. Lymphomas, lymphocytic leukemias, and ... Hematological malignancies may derive from either of the two major blood cell lineages: myeloid and lymphoid cell lines. The ... "Facts & Statistics". The Leukemia and Lymphoma Society. Retrieved 3 November 2009. "Facts about blood cancers". Leukaemia & ... The use of rituximab has been established for the treatment of B-cell-derived hematologic malignancies, including follicular ...
*  Proteinuria
... plasma cell dyscrasias Multiple myeloma Waldenstrom's macroglobulinemia Other malignancies Chronic lymphocytic leukemia Rare ... Amyloidosis Pre-malignant plasma cell dyscrasias: Monoclonal Gammopathy of Undetermined Significance Smoldering multiple ... cases of other Lymphoid leukemias Rare cases of Lymphomas Conventionally, proteinuria is diagnosed by a simple dipstick test, ... Fanconi syndrome in association with Wilson disease Hypertensive nephrosclerosis Interstitial nephritis Sickle cell disease ...
*  Paraproteinemia
... but usually B-cell Non-Hodgkin lymphomas with a plasma cell component. Myeloma Plasmacytoma Lymphoplasmacytic lymphoma ... Causes of paraproteinemia include the following:[citation needed] Leukemias and lymphomas of various types, ... It is sometimes considered equivalent to plasma cell dyscrasia. ... Plasma cell dyscrasia Monoclonal gammopathy of undetermined ... Idiopathic (no discernible cause): some of these will be revealed as leukemias or lymphomas over the years. Monoclonal ...
*  Isatuximab
... it is in phase II trials for multiple myeloma and T-cell leukemia. A phase III combination trial for plasma cell myeloma is ... Clinical trial number NCT02999633 for "Safety and Efficacy of Isatuximab in Lymphoblastic Leukemia" at ClinicalTrials.gov ...
*  Heavy chain disease
... is a form of paraproteinemia and plasma cell dyscrasia that involves the proliferation of cells producing ... The IgM type of heavy chain disease, μHCD, is often misdiagnosed as chronic lymphoid leukemia (CLL) because the two diseases ... "Heavy Chain Diseases: Plasma Cell Disorders: Merck Manual Home Edition". Retrieved 2008-02-29. Goossens T, Klein U, Küppers R ( ... Franklin's disease (gamma heavy chain disease) It is a very rare B-cell lymphoplasma cell proliferative disorder which may be ...
*  Erythrocyte sedimentation rate
... sickle cell anemia, leukemia, low plasma protein (due to liver or kidney disease) and congestive heart failure. The basal ESR ... the high proportion of fibrinogen in the blood causes red blood cells to stick to each other. The red cells form stacks called ... The red blood cell count, whose values are inversely related to ESR, is affected in carriers of this SNP. This mutation is ... The erythrocyte sedimentation rate (ESR or sed rate) is the rate at which red blood cells sediment in a period of one hour. It ...
*  CD20
... but not on either early pro-B cells or plasma blasts and plasma cells. It is found on B-cell lymphomas, hairy cell leukemia, B- ... Because CD20 remains present on the cells of most B-cell neoplasms, and is absent on otherwise similar appearing T-cell ... cell chronic lymphocytic leukemia, and melanoma cancer stem cells. The expression of CD20 is regulated by the chemokine ... Tamayose K, Sato N, Ando J, Sugimoto K, Oshimi K (December 2002). "CD3-negative, CD20-positive T-cell prolymphocytic leukemia: ...
*  Dock10
... cells in response to the cytokine IL-4. This suggests that Dock10 may have a role in B-cell activation and proliferation. ... mediates recruitment to the plasma membrane. The DHR2 domain of Dock10 appears to bind to the small G proteins Cdc42, TC10 and ... a study in lymphocytes has shown that Dock10 expression is upregulated in B-lymphocytes and Chronic Lymphocytic Leukemia (CLL) ... Meller N, Merlot S, Guda C (2005). "CZH proteins: a new family of Rho-GEFs". J. Cell Sci. 118 (Pt 21): 4937-46. doi:10.1242/jcs ...
*  Đái Duy Ban
Surface Coat of Plasma Membrane of L 1210 lymphoid Leukemia Cells. A Cytochemical study, Folia Histochemica et cytochemica. 19 ... Membrane Surrounding Lipid Vacuoles in L 1210 lymphoid Leukemic Cells. Cell structure and Function 5, 211-215, 1980. Dai Duy ... Cytochemical visualization of calcium binding to the plasma membrane of L 1210 lymphoid leukemic cells. Acta histochem 65, 160 ... When the test has been carried out later, the tumor has become normal and no longer had the cancer cell. He is not only spends ...