Acute megakaryoblastic leukemia
... (AMKL) is life-threatening leukemia in which malignant megakaryoblasts proliferate abnormally ... Wang SA, Hasserjian RP (July 2015). "Acute Erythroleukemias, Acute Megakaryoblastic Leukemias, and Reactive Mimics: A Guide to ... Gassmann W, Löffler H (1995). "Acute megakaryoblastic leukemia". Leukemia & Lymphoma. 18 Suppl 1: 69-73. doi:10.3109/ ... "GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome". Blood. 101 (11): 4301-4. doi: ...
List of hematologic conditions
Gassmann W, Winfried; Löffler H. (1995). "Acute megakaryoblastic leukemia". Leuk. Lymphoma. 18 Suppl 1: Leukemia and Lymphoma. ... Löwenberg B, Downing JR, Burnett A (Sep 30, 1999). "Acute myeloid leukemia". N Engl J Med (Review). 341 (14): 1051-62. doi: ... Leukemia is a malignancy producing of white blood cells in bone marrow. It can be a serious disease if not treated early. ... These cancers include leukemias, lymphomas, and myelomas. These particular types of cancers can arise as defected mature cell ...
Transient myeloproliferative disease
TMD may be followed within weeks to ~5 years by a subtype of myeloid leukemia, acute megakaryoblastic leukemia. AMKL is ... Gassmann W, Löffler H (1995). "Acute megakaryoblastic leukemia". Leukemia & Lymphoma. 18 Suppl 1: 69-73. doi:10.3109/ ... It is not known if these regimens have an impact on the development of acute megakaryoblastic leukemia. Currently, it is ... Moreover, ~10% of individuals diagnosed with TMD develop acute megakaryoblastic leukemia at some time during the 5 years ...
GATA1
Acute megakaryoblastic leukemia is a subtype of acute myeloid leukemia that is extremely rare in adults and, although still ... It resolves totally within ~3 months but in the following 1-3 years progresses to acute megakaryoblastic leukemia in 20% to 30 ... These same individuals can develop secondary mutations in other genes that results in acute megakaryoblastic leukemia. GATA1 ... Gruber TA, Downing JR (August 2015). "The biology of pediatric acute megakaryoblastic leukemia". Blood. 126 (8): 943-9. doi: ...
Acute myeloid leukemia
Bloomfield CD, Brunning RD (September 1985). "FAB M7: acute megakaryoblastic leukemia--beyond morphology". Annals of Internal ... "Acute Myeloid Leukemia Staging". Retrieved 26 August 2011. Mihova D. "Leukemia acute - Acute myeloid leukemia with minimal ... Acute leukemias of ambiguous lineage (also known as mixed phenotype or biphenotypic acute leukemia) occur when the leukemic ... "acute leukemia" in 1889 to differentiate rapidly progressive and fatal leukemias from the more indolent chronic leukemias. The ...
Acute panmyelosis with myelofibrosis
May 2005). "Acute panmyelosis with myelofibrosis: an entity distinct from acute megakaryoblastic leukemia". Mod. Pathol. 18 (5 ... Acute myeloid leukemia Panmyelosis Myelofibrosis (Articles with short description, Short description is different from Wikidata ... Controversy remains today whether this disorder is a subtype of acute myeloid leukemia or myelodysplastic syndromes; however, ... All articles with unsourced statements, Articles with unsourced statements from December 2008, Acute myeloid leukemia). ...
RBM6
2007). "A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia". Blood. 110 (1): 323-33. doi:10.1182/blood-2006-10- ...
Mediastinal germ cell tumor
Rare cases of adult onset acute megakaryoblastic leukemia are associated with malignant mediastinal germ cell tumor. In these ... the mediastinal germ cell tumor develops before or concomitantly with but not after acute megakaryoblastic leukemia. The three ...
Myeloid leukemia
Chronic myelogenous leukemia: A cancer of the white blood cells. Acute megakaryoblastic leukemia: A life-threatening leukemia ... Myeloid leukemia is a type of leukemia affecting myeloid tissue. Types include: Acute myeloid leukemia: A cancer of the myeloid ...
TMEM241
For instance, in cases of acute megakaryoblastic leukemia, TMEM241 was found to be one of the most upregulated genes. In ... "Integrated differential transcriptome maps of Acute Megakaryoblastic Leukemia (AMKL) in children with or without Down Syndrome ...
MKL1
July 2001). "Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia". Nature ... MKL/megakaryoblastic leukemia 1 (also termed MRTFA/myocardin related transcription factor A) is a protein that in humans is ... "Entrez Gene: MKL1 megakaryoblastic leukemia (translocation) 1". Vartiainen MK, Guettler S, Larijani B, Treisman R (June 2007 ... Cen B, Selvaraj A, Burgess RC, Hitzler JK, Ma Z, Morris SW, Prywes R (September 2003). "Megakaryoblastic leukemia 1, a potent ...
RBM15
... of acute megakaryoblastic leukemia". Nat Genet. 28 (3): 220-1. doi:10.1038/90054. PMID 11431691. S2CID 36236342. Mercher T, ... 2005). "RBM15-MKL1 (OTT-MAL) fusion transcript in an adult acute myeloid leukemia patient". Am. J. Hematol. 79 (1): 43-5. doi: ... translocation of acute megakaryocytic leukemia". Proc Natl Acad Sci U S A. 98 (10): 5776-9. Bibcode:2001PNAS...98.5776M. doi: ...
MiR-125
Upregulation of miR-125b occurs in patients with B-cell acute lymphoblastic leukemia, megakaryoblastic leukemia, myelodysplasia ... and acute myeloid leukemia. While miR-125a acts as an oncogenic miRNA in non-blood cancers, its oncogenic functions have been ... Leukemia. 26 (9): 2011-2018. doi:10.1038/leu.2012.90. ISSN 0887-6924. PMID 22456625. S2CID 30128839. Emmrich, Stephan; Rasche, ...
PICALM
"High incidence of CALM-AF10 fusion and the identification of a novel fusion transcript in acute megakaryoblastic leukemia in ... 2007). "Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/ ... 2003). "A novel chromosomal inversion at 11q23 in infant acute myeloid leukemia fuses MLL to CALM, a gene that encodes a ... "Expression of a CALM-AF10 fusion gene leads to Hoxa cluster overexpression and acute leukemia in transgenic mice". Cancer Res. ...
Janus kinase 3
In addition, oncogenic JAK3 mutations have been identified in acute megakaryoblastic leukemia, T-cell prolymphocytic leukemia, ... JAK3 activating mutations are found in 16% of T-cell acute lymphoblastic leukemia (T-ALL) patients. ... causing T-cell acute lymphoblastic leukemia in a mouse model". Blood. 124 (20): 3092-100. doi:10.1182/blood-2014-04-566687. ... sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia ...
LL-100 panel
"Acute megakaryoblastic leukemia: establishment of a new cell line (MKPL-1) in vitro and in vivo". Leukemia. 6 (6): 588-94. PMID ... Asou, H; Tashiro, S; Hamamoto, K; Otsuji, A; Kita, K; Kamada, N (1 May 1991). "Establishment of a human acute myeloid leukemia ... Findley HW, Jr; Cooper, MD; Kim, TH; Alvarado, C; Ragab, AH (December 1982). "Two new acute lymphoblastic leukemia cell lines ... Kishi, K (1985). "A new leukemia cell line with Philadelphia chromosome characterized as basophil precursors". Leukemia ...
Down syndrome
... acute megakaryoblastic leukemia), is 500 times more common. Acute megakaryoblastic leukemia (AMKL) is a leukemia of ... In particular, acute lymphoblastic leukemia is 20 times more common and the megakaryoblastic form of acute myeloid leukemia ( ... including acute lymphoblastic leukemia (ALL) and acute megakaryoblastic leukemia (AMKL) is increased while the risk of other ... pathogenesis and clinical aspects of acute lymphoblastic leukemia in children with Down syndrome". Leukemia. 30 (9): 1816-23. ...
List of diseases (A)
... aniridia Acute lymphocytic leukemia Acute megakaryoblastic leukemia Acute monoblastic leukemia Acute monocytic leukemia Acute ... leukemia without maturation Acute myelocytic leukemia Acute myelogenous leukemia Acute myeloid leukemia Acute myeloid leukemia ... leukemia type 1 Acute myeloblastic leukemia type 2 Acute myeloblastic leukemia type 3 Acute myeloblastic leukemia type 4 Acute ... myeloblastic leukemia type 5 Acute myeloblastic leukemia type 6 Acute myeloblastic leukemia type 7 Acute myeloblastic leukemia ...
Myelodysplastic syndrome
... progresses to acute megakaryoblastic leukemia. The elimination of other causes of cytopenias, along with a dysplastic bone ... September 2007). "Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia". Journal of ... Seewald L, Taub JW, Maloney KW, McCabe ER (September 2012). "Acute leukemias in children with Down syndrome". Molecular ... Block M, Jacobson LO, Bethard WF (July 1953). "Preleukemic acute human leukemia". Journal of the American Medical Association. ...
Hematologic disease
Acute myelogenous leukemia (AML) Acute megakaryoblastic leukemia (AMKL), a sub-type of acute myelogenous leukemia Chronic ... T-cell prolymphocytic leukemia (T-PLL) B-cell prolymphocytic leukemia (B-PLL) Chronic neutrophilic leukemia (CNL) Hairy cell ... Myelomas Multiple myeloma Waldenström macroglobulinemia Plasmacytoma Leukemias increased WBC Acute lymphocytic leukemia (ALL) ... leukemia (HCL) T-cell large granular lymphocyte leukemia (T-LGL) Aggressive NK-cell leukemia Hemochromatosis Asplenia ...
List of OMIM disorder codes
... acute myeloid; 601626; FLT3 Leukemia, acute myeloid; 601626; KIT Leukemia, acute myeloid; 601626; LPP Leukemia, acute myeloid; ... PTPN11 Leukemia, megakaryoblastic, of Down syndrome; 190685; GATA1 Leukemia, megakaryoblastic, with or without Down syndrome; ... acute myelogenous; 601626; JAK2 Leukemia, acute myeloid; 601626; MLF1 Leukemia, acute myeloid; 601626; NSD1 Leukemia, acute ... acute myeloid; 601626; NUP214 Leukemia, acute myeloid; 601626; PICALM Leukemia, acute myeloid; 601626; RUNX1 Leukemia, acute ...
Tumors of the hematopoietic and lymphoid tissues
Lymphomas, lymphocytic leukemias, and myeloma are from the lymphoid line, while acute and chronic myelogenous leukemia, ... leukaemia Acute monoblastic and monocytic leukaemia Pure erythroid leukaemia Acute megakaryoblastic leukaemia Acute basophilic ... NOS Mixed-phenotype acute leukaemia, T/myeloid, NOS Mixed-phenotype acute leukaemia, NOS, rare types Acute leukaemias of ... dendritic cell neoplasm Acute leukaemias of ambiguous lineage Acute undifferentiated leukaemia Mixed-phenotype acute leukaemia ...
GNLY
Kitamura N, Koshiba M, Horie O, Ryo R (2002). "Expression of granulysin mRNA in the human megakaryoblastic leukemia cell line ... June 2004). "Enhanced granulysin mRNA expression in urinary sediment in early and delayed acute renal allograft rejection". ...
Leukemia
Subtypes of AML include acute promyelocytic leukemia, acute myeloblastic leukemia, and acute megakaryoblastic leukemia. Chronic ... Nearly all leukemias appearing in pregnant women are acute leukemias. Acute leukemias normally require prompt, aggressive ... There are four main types of leukemia-acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic ... Subtypes include precursor B acute lymphoblastic leukemia, precursor T acute lymphoblastic leukemia, Burkitt's leukemia, and ...
International Classification of Diseases for Oncology
MLL M9910/3 Acute megakaryoblastic leukemia, NOS Megakaryocytic leukemia (FAB-M7) M9920/3 Acute myeloid leukemia and ... Acute myelogenous leukemia Acute non-lymphocytic leukemia Acute granulocytic leukemia Acute myelogenous leukemia Acute ... NOS Acute lymphocytic leukemia Acute lymphoid leukemia Acute lymphatic leukemia Acute lymphoblastic leukemia, L2 type, NOS FAB ... Stem cell leukemia M9805/3 Acute biphenotypic leukemia Acute leukemia of ambiguous lineage Acute mixed lineage leukemia Acute ...