Promyelocytic leukemia protein
Experimental Cell Research. 297 (1): 118-26. doi:10.1016/j.yexcr.2004.03.014. PMID 15194430. Kurki S, Latonen L, Laiho M ( ... Promyelocytic leukemia protein (PML) (also known as MYL, RNF71, PP8675 or TRIM19) is the protein product of the PML gene. PML ... "PML promyelocytic leukemia [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2016-12-06. Pearson M, ... Promyelocytic leukemia protein has been shown to interact with: ANKRD2, CREB-binding protein, Cyclin T1, Death associated ...
Leukemia & Lymphoma Society
Krueger, Gretchen (2008). Hope and suffering: children, cancer, and the paradox of experimental medicine. Baltimore: Johns ... "Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K". vivo.health.unm.edu. Retrieved ... In 1987 the Leukemia Society of America partnered with the Leukemia Research Fund (U.K.). It launched the peer-reviewed medical ... In 1968, the Leukemia Society of America published Closing In, Research on Leukemia, a book summarizing its progress in ...
CD34
Nakamura Y, Komano H, Nakauchi H (February 1993). "Two alternative forms of cDNA encoding CD34". Experimental Hematology. 21 (2 ... Leukemia Research. 9 (1): 1-9. doi:10.1016/0145-2126(85)90016-5. PMID 3857402. Tindle RW. Katz F. Martin H. Watt D. Catovsky D ... Experimental Hematology. 21 (5): 614-622. PMID 8513861. Chen CZ, Li L, Li M, Lodish HF (October 2003). "The endoglin(positive) ... progenitor/stem cells in TEL/AML1-positive acute lymphoblastic leukemia are genetically and functionally normal". Blood. 100 (2 ...
ZNF384
"CIZ gene rearrangements in acute leukemia: report of a diagnostic FISH assay and clinical features of nine patients". Leukemia ... Experimental Cell Research. 312 (7): 1194-204. doi:10.1016/j.yexcr.2006.02.001. PMID 16510139. ZNF384+protein,+human at the U.S ... with the transcription factor CIZ/NMP4 in acute leukemia". Cancer Research. 62 (19): 5408-12. PMID 12359745. Suzuki Y, ... have been observed in acute leukemia. GRCh38: Ensembl release 89: ENSG00000126746 - Ensembl, May 2017 GRCm38: Ensembl release ...
NF-κB
Advances in Experimental Medicine and Biology. Vol. 788. pp. 7-17. doi:10.1007/978-94-007-6627-3_2. ISBN 978-94-007-6626-6. ... Garg A, Aggarwal BB (June 2002). "Nuclear transcription factor-kappaB as a target for cancer drug development". Leukemia. 16 (6 ... Advances in Experimental Medicine and Biology. Vol. 610. pp. 112-127. doi:10.1007/978-0-387-73898-7_9. ISBN 978-0-387-73897-0. ... Advances in Experimental Medicine and Biology. Vol. 928. Springer International Publishing. pp. 329-373. doi:10.1007/978-3-319- ...
K562 cells
Lozzio BB, Lozzio CB (1979). "Properties and usefulness of the original K-562 human myelogenous leukemia cell line". Leukemia ... Experimental Cell Research. 344 (1): 40-52. doi:10.1016/j.yexcr.2016.04.010. PMC 4879089. PMID 27086164. Yang C, Cai H, Meng X ... Drexler HG (2000). The Leukemia-Lymphoma Cell Line Factsbook. San Diego: Academic Press. Klein E, Ben-Bassat H, Neumann H, ... K562 cells were the first human immortalised myelogenous leukemia cell line to be established. K562 cells are of the ...
Thymidine kinase in clinical chemistry
The experimental method first developed by Gronowitz et al. used quantities of radioisotope much higher than those used in ... Leukemias normally do not normally present major diagnostic difficulties, as the microscopic analysis of the cells in blood ... A very interesting case is the myelodysplastic syndrome: some rapidly change to acute leukemia, whereas others remain indolent ... Identification of those tending to change to overt leukemia is important for the treatment. A relationship between the ...
Retinol
It has numerous applications in the experimental induction of stem cell differentiation; amongst these are the differentiation ... Oren T, Sher JA, Evans T (November 2003). "Hematopoiesis and retinoids: development and disease". Leukemia & Lymphoma. 44 (11 ... Evans T (September 2005). "Regulation of hematopoiesis by retinoid signaling". Experimental Hematology. 33 (9): 1055-1061. doi: ...
Primary myelofibrosis
... or chronic megakaryocytic leukemia? Further thoughts on the nosology of the clonal myeloid disorders". Leukemia. 19 (7): 1139- ... November 2010). "Oxidative stress is increased in primary and post-polycythemia vera myelofibrosis". Experimental Hematology. ... Primary myelofibrosis can begin with a blood picture similar to that found in polycythemia vera or chronic myeloid leukemia. ... Kröger N, Mesa RA (March 2008). "Choosing between stem cell therapy and drugs in myelofibrosis". Leukemia. 22 (3): 474-486. doi ...
Physical oncology
Thus, the experimental evidence showing that carcinogenesis is a process bound to emerge a break geometry of the tissue ... This "one-to-one and first-degree equation" allowed Chronic Myeloid Leukemia to be controlled by imatinib. The defective BCR- ... But the contradictory experimental facts are not lacking: the carcinogens are not all mutagens (hormones...); the target of ... Advances in Experimental Medicine and Biology. Vol. 773. Springer, New York, NY. pp. 435-470. doi:10.1007/978-1-4899-8032-8_20 ...
MicroRNA
Giza DE, Calin GA (2015). "MicroRNA and Chronic Lymphocytic Leukemia". MicroRNA: Cancer. Advances in Experimental Medicine and ... These experimental findings suggest that let-7 inhibition could represent a new therapy for obesity and type 2 diabetes. miRNAs ... The first human disease known to be associated with miRNA deregulation was chronic lymphocytic leukemia. Many other miRNAs also ... The first human disease associated with deregulation of miRNAs was chronic lymphocytic leukemia. In this disorder, the miRNAs ...
Shimon Slavin
Danny Cunniff Leukemia Research Laboratory, Hadassah Medical Center Siegel-Itzkovich J (6 July 2002). "Scientists use gene ... Karussis D, Slavin S (Aug 2004). "Hematopoietic stem cell transplantation in multiple sclerosis: experimental evidence to ... Slavin S, Naparstek E, Nagler A, Ackerstein A, Kapelushnik J, Or R (Dec 1995). "Allogeneic cell therapy for relapsed leukemia ... In 1977 Slavin discovered the first animal model of B-cell leukemia/lymphoma (BCL1), which provided an opportunity to ...
HOXB6
... has been implicated in the development of acute myeloid leukemia (AML). Acute myeloid leukemia is a cancer of the blood cells, ... The Journal of Experimental Zoology. 285 (1): 76-84. doi:10.1002/(SICI)1097-010X(19990415)285:1. 3.0.CO;2-K. PMID 10327653. ... "Modulation of homeobox B6 and B9 genes expression in human leukemia cell lines during myelomonocytic differentiation". Leukemia ... The Journal of Experimental Zoology. 264 (3): 323-36. doi:10.1002/jez.1402640311. PMID 1358998. Shen WF, Detmer K, Simonitch- ...
PRAME
However, unlike these other CT antigens, this gene is also expressed in acute leukemias. The overexpression of PRAME in tumor ... Experimental and Clinical Immunogenetics. 15 (1): 19-32. doi:10.1159/000019050. PMID 9619397. S2CID 25993773. Matsushita M, ... Steinbach D, Viehmann S, Zintl F, Gruhn B (Oct 2002). "PRAME gene expression in childhood acute lymphoblastic leukemia". Cancer ... Leukemia & Lymphoma. 44 (3): 439-44. doi:10.1080/1042819021000035725. PMID 12688312. S2CID 29064098. Bonaldo MF, Lennon G, ...
Deaths in June 2012
"O'Hara dies of leukemia". June 26, 2012. "Actress Doris Singleton dies". variety.com. 27 June 2012. Retrieved 2012-06-28. " ... Stephen Dwoskin, 73, American experimental filmmaker. Fred Dyke, 89, Canadian curler. Éric Gaudibert, 75, Swiss composer. Kamal ... Mario O'Hara, 68, Filipino film director, leukemia. Doris Singleton, 92, American actress (I Love Lucy, My Three Sons). ... Masazumi Harada, 77, Japanese doctor, researcher of Minamata disease, acute myeloid leukemia. Norman F. Lent, 81, American ...
John Auer
Auer rods are found only in neoplastic cells and are used in the diagnosis of acute promyelocytic leukemia, though they do not ... John Auer was a member of the following societies and organizations: American Society for Pharmacology and Experimental ... AUER, JOHN (June 1906). "Some Hitherto Undescribed Structures Found in the Large Lymphocytes of a Case of Acute Leukemia". The ... Roth, George B. (1949-03-01). "John Auer 1875-1948". Journal of Pharmacology and Experimental Therapeutics. 95 (3): 285-286. ...
Philadelphia chromosome
Burke BA, Carroll M (June 2010). "BCR-ABL: a multi-faceted promoter of DNA mutation in chronic myelogeneous leukemia". Leukemia ... The Journal of Experimental Medicine. 179 (6): 1855-1865. doi:10.1084/jem.179.6.1855. PMC 2191514. PMID 8195713. Steelman LS, ... and occasionally in acute myelogenous leukemia (AML) as well as mixed-phenotype acute leukemia (MPAL). The chromosomal defect ... Chronic myelogenous leukemia Wapner J (2014). The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the ...
Camidanlumab tesirine
... and for the treatment of B-cell acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). The human monoclonal ... The experimental drug, developed by ADC Therapeutics is being tested in clinical trials for the treatment of B-cell Hodgkin's ... CD25 is over-expressed in a wide range of hematological malignancies, such as leukemias and lymphomas. After binding to a CD25- ... August 1998). "Clinical trials with an anti-CD25 ricin A-chain experimental and immunotoxin (RFT5-SMPT-dgA) in Hodgkin's ...
CD19
... acute lymphoblastic leukemia (ALL), and chronic lymphocytic leukemia (CLL). The majority of B cell malignancies express normal ... The most current experimental anti-CD19 immunotoxins in development work by exploiting the widespread presence of CD19 on B ... "CD19 antigen in leukemia and lymphoma diagnosis and immunotherapy". Leukemia & Lymphoma. 18 (5-6): 385-97. doi:10.3109/ ... Haas KM, Tedder TF (2005). Mechanisms of Lymphocyte Activation and Immune Regulation X. Advances in Experimental Medicine and ...
Christine Harrison
"Leukemia caused by chromosome catastrophe". ScienceDaily. Retrieved 2019-07-31. www-core (webteam). "Leukaemia caused by ... Reviews in Clinical and Experimental Hematology. 6 (2): 91-113. doi:10.1046/j.1468-0734.2002.00069.x. ISSN 1468-0734. PMID ... She works on acute leukemia and used cytogenetics to optimise treatment protocols. Harrison attended an all girls school, where ... Harrison is investigating new treatments to target leukemia cells. Since 2008 Harrison has served as a Professor of ...
Bovine leukemia virus
Sheep are very susceptible to experimental inoculation and develop tumours more often and at a younger age than cattle. A ... "Bovine leukemia virus". NCBI Taxonomy Browser. 11901. "Bovine Leukemia Virus (BLV)". APHIS (Animal and Plant Health Inspection ... Bovine leukemia virus (BLV) is a retrovirus which causes enzootic bovine leukosis in cattle. It is closely related to the human ... One can use the experience with BLV for understanding HTLV-I induced diseases like ATL (adult T-cell leukemia) and HAM/TSP ( ...
Apolizumab
... using a stepped-up dosing schedule in patients with chronic lymphocytic leukemia and acute leukemia". Leukemia & Lymphoma. 50 ( ... Bayes M, Rabasseda X, Prous JR (November 2003). "Gateways to clinical trials". Methods and Findings in Experimental and ... Leukemia & Lymphoma. 47 (10): 2147-2154. doi:10.1080/10428190600757944. PMID 17071489. S2CID 24080973. Lin TS, Stock W, Xu H, ...
List of agnostics
He (along with Alan Hodgkin) won the 1963 Nobel Prize in Physiology or Medicine for his experimental and mathematical work on ... Thomas developed bone marrow transplantation as a treatment for leukemia. John Tyndall (1820-1893): Prominent 19th century ... He played a fundamental role in the first experimental demonstration of nuclear fusion and also the development of the atomic ... American experimental physicist. He, along with David Lee, as senior researchers, and then graduate student Douglas Osheroff, ...
ETV6
"ETV6 mutations in early immature human T cell leukemias". The Journal of Experimental Medicine. 208 (13): 2571-9. doi:10.1084/ ... chronic myelomonocytic leukemia, acute myelocytic leukemia, B cell acute lymphoblastic leukemia, mixed phenotype acute leukemia ... acute lymphocytic leukemia (ALL), Philadelphia chromosome negative chronic myelogenous leukemia (Ph(-)CML), myelodysplastic ... The acute lymphoblastic leukemia associated with L349P or N385fs mutations in ETV6 appeared far less sensitive to standard ...
STAT3
A direct connection between the PTEN-Akt-FOXO axis (suppressive) and the leukemia inhibitory factor receptor beta (LIFRbeta)- ... Experimental & Molecular Medicine. 40 (5): 479-85. doi:10.3858/emm.2008.40.5.479. PMC 2679355. PMID 18985005. Spiekermann K, ... "Constitutive activation of STAT transcription factors in acute myelogenous leukemia". European Journal of Haematology. 67 (2): ...
Cytochalasin B
Tanaka, Y.; Yoshihara, K.; Tsuyuki, M.; Kamiya, T. (1994). "Apoptosis Induced by Adenosine in Human Leukemia HL-60 Cells". ... Experimental Cell Research. 213 (1): 242-559. doi:10.1006/excr.1994.1196. PMID 8020596. Smith, GF; Ridler, MA; Faunch, JA (16 ... It blocks adenosine-induced apoptotic body formation without affecting activation of endogenous ADP-ribosylation in leukemia HL ... Experimental Cell Research. 204 (2): 268-277. doi:10.1006/excr.1993.1033. PMID 8440324. (CS1 errors: requires URL, Vague or ...
Deoxycytidine kinase
"Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication". The Journal of Experimental Medicine. ...
ARPC1B
Rassenti LZ, Kipps TJ (Apr 1997). "Lack of allelic exclusion in B cell chronic lymphocytic leukemia". The Journal of ... Experimental Medicine. 185 (8): 1435-45. doi:10.1084/jem.185.8.1435. PMC 2196272. PMID 9126924. Zhao X, Yang Z, Qian M, Zhu X ( ...
Michael Brecker
In late 2005, he was the recipient of an experimental partial matching stem cell transplant. By late 2006, he appeared to be ... Brecker died from complications of leukemia in a Manhattan hospital. His funeral was held on January 15, 2007, in Hastings-on- ... It documents Brecker's battle with leukemia, and the production of his final recording. By going public with his illness, ... Deaths from leukemia, Jazz musicians from Philadelphia, P-Funk members, Saturday Night Live Band members, Jazz tenor ...
SIGIRR
... is downregulated in chronic lymphocytic leukemia". Leukemia & Lymphoma. 58 (10): 2419-2425. doi:10.1080/10428194.2017.1295142. ... Clinical and Experimental Immunology. 162 (2): 348-61. doi:10.1111/j.1365-2249.2010.04254.x. PMC 2996602. PMID 21077278. Ueno- ... Its reduced expression was also found in patients with chronic lymphoid leukemia, or in cells from colonic cancer. In human ...
Cold Spring Harbor Laboratory
Richter, MN; MacDowell (1930). "Studies on Leukemia in Mice: I: The Experimental Transmission of Leukemia". J. Exp. Med. 51 (4 ... In 1904, the Carnegie Institution of Washington established the Station for Experimental Evolution at Cold Spring Harbor on an ... E. Carleton MacDowell in 1928 discovered a strain of mouse called C58 that developed spontaneous leukemia - an early mouse ... leukemia biologist, winner of the Paul Marks Prize for Cancer Research. Carol Greider, discovered relationship between cellular ...
Oxidative stress
In hematological cancers, such as leukemia, the impact of oxidative stress can be bilateral. Reactive oxygen species can ... Hwang O (March 2013). "Role of oxidative stress in Parkinson's disease". Experimental Neurobiology. 22 (1): 11-17. doi:10.5607/ ... Udensi UK, Tchounwou PB (December 2014). "Dual effect of oxidative stress on leukemia cancer induction and treatment". Journal ... DNA Double-Strand Break Accumulation in Alzheimer's Disease: Evidence from Experimental Models and Postmortem Human Brains. Mol ...